메뉴 건너뛰기




Volumn 96, Issue 3, 2004, Pages 341-345

C677T polymorphism of the methylenetetrahydrofolate reductase gene is a risk factor of adverse events after coronary revascularization

Author keywords

Coronary artery bypass graft; Coronary artery disease; Follow up; Homocysteine; MTHFR genotype; Percutaneous transluminal coronary angioplasty

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 4143111407     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2003.06.022     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 0025756673 scopus 로고
    • Hyperhomocysteinemia: An independent risk factor for vascular disease
    • Clarke R., Daly L., Robinson K., et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N. Engl. J. Med. 324:1991;1149-1155
    • (1991) N. Engl. J. Med. , vol.324 , pp. 1149-1155
    • Clarke, R.1    Daly, L.2    Robinson, K.3
  • 2
    • 0033304841 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and the endocrine system: Implications for atherosclerosis and thrombosis
    • Fonseca V., Guba S.C., Fink L.M. Hyperhomocysteinemia and the endocrine system: implications for atherosclerosis and thrombosis. Endocr. Rev. 20:1999;738-759
    • (1999) Endocr. Rev. , vol.20 , pp. 738-759
    • Fonseca, V.1    Guba, S.C.2    Fink, L.M.3
  • 4
    • 0034641652 scopus 로고    scopus 로고
    • Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease
    • Anderson J.L., Muhlestein J.B., Horne B.D., et al. Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease. Circulation. 102:2000;1227-1232
    • (2000) Circulation , vol.102 , pp. 1227-1232
    • Anderson, J.L.1    Muhlestein, J.B.2    Horne, B.D.3
  • 5
    • 0033934944 scopus 로고    scopus 로고
    • Homocysteine as a risk factor for restenosis after coronary angioplasty
    • Morita H., Kurihara H., Kuwaki T., et al. Homocysteine as a risk factor for restenosis after coronary angioplasty. Thromb. Haemost. 84:2000;27-31
    • (2000) Thromb. Haemost. , vol.84 , pp. 27-31
    • Morita, H.1    Kurihara, H.2    Kuwaki, T.3
  • 7
    • 0036558642 scopus 로고    scopus 로고
    • Association of plasma homocysteine with restenosis after percutaneous coronary angioplasty
    • Schnyder G., Roffi M., Flammer Y., Pin R., Hess O.M. Association of plasma homocysteine with restenosis after percutaneous coronary angioplasty. Eur. Heart J. 23:2002;726-733
    • (2002) Eur. Heart J. , vol.23 , pp. 726-733
    • Schnyder, G.1    Roffi, M.2    Flammer, Y.3    Pin, R.4    Hess, O.M.5
  • 8
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P., Blom H.J., Milos R., et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat. Genet. 10:1995;111-113
    • (1995) Nat. Genet. , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 9
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques P.F., Bostom A.G., Williams R.R., et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation. 93:1996;7-9
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 10
    • 0030934392 scopus 로고    scopus 로고
    • Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
    • Christensen B., Frosst P., Lussier-Cacan S., et al. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 17:1997;569-573
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 569-573
    • Christensen, B.1    Frosst, P.2    Lussier-Cacan, S.3
  • 11
    • 0030826587 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
    • Kluijtmans L.A., Kastelein J.J., Lindemans J., et al. Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 96:1997;2573-2577
    • (1997) Circulation , vol.96 , pp. 2573-2577
    • Kluijtmans, L.A.1    Kastelein, J.J.2    Lindemans, J.3
  • 12
    • 0029827313 scopus 로고    scopus 로고
    • Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation
    • Gallagher P.M., Meleady R., Shields D.C., et al. Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation. Circulation. 94:1996;2154-2158
    • (1996) Circulation , vol.94 , pp. 2154-2158
    • Gallagher, P.M.1    Meleady, R.2    Shields, D.C.3
  • 13
    • 0029806746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
    • Ma J., Stampfer M.J., Hennekens C.H., et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation. 94:1996;2410-2416
    • (1996) Circulation , vol.94 , pp. 2410-2416
    • Ma, J.1    Stampfer, M.J.2    Hennekens, C.H.3
  • 14
    • 0029968008 scopus 로고    scopus 로고
    • Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study
    • Schmitz C., Lindpaintner K., Verhoef P., Gaziano J.M., Buring J. Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study. Circulation. 94:1996;1812-1814
    • (1996) Circulation , vol.94 , pp. 1812-1814
    • Schmitz, C.1    Lindpaintner, K.2    Verhoef, P.3    Gaziano, J.M.4    Buring, J.5
  • 15
    • 0030897112 scopus 로고    scopus 로고
    • Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
    • Morita H., Taguchi J., Kurihara H., et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation. 95:1997;2032-2036
    • (1997) Circulation , vol.95 , pp. 2032-2036
    • Morita, H.1    Taguchi, J.2    Kurihara, H.3
  • 16
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
    • Brattstrom L., Wilcken D.E., Ohrvik J., Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation. 98:1998;2520-2526
    • (1998) Circulation , vol.98 , pp. 2520-2526
    • Brattstrom, L.1    Wilcken, D.E.2    Ohrvik, J.3    Brudin, L.4
  • 17
    • 0031950779 scopus 로고    scopus 로고
    • Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and the risk of coronary artery disease
    • Reinhardt D., Sigusch H.H., Vogt S.F., Farker K., Muller S., Hoffmann A. Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and the risk of coronary artery disease. Eur. J. Clin. Invest. 28:1998;20-23
    • (1998) Eur. J. Clin. Invest. , vol.28 , pp. 20-23
    • Reinhardt, D.1    Sigusch, H.H.2    Vogt, S.F.3    Farker, K.4    Muller, S.5    Hoffmann, A.6
  • 18
    • 0035880967 scopus 로고    scopus 로고
    • MTHFR 677 C→T mutation: A predictor of early-onset coronary artery disease risk
    • Payne D.A., Chamoun A.J., Seifert S.L., Stouffer G.A. MTHFR 677 C→T mutation: a predictor of early-onset coronary artery disease risk. Thromb. Res. 103:2001;275-279
    • (2001) Thromb. Res. , vol.103 , pp. 275-279
    • Payne, D.A.1    Chamoun, A.J.2    Seifert, S.L.3    Stouffer, G.A.4
  • 19
    • 0037090494 scopus 로고    scopus 로고
    • Plasma homocysteine methylenetetrahydrofolate reductase genotypes and age at onset of symptoms of myocardial ischemia
    • Mager A., Battler A., Birnbaum Y., Magal N., Shohat M. Plasma homocysteine methylenetetrahydrofolate reductase genotypes and age at onset of symptoms of myocardial ischemia. Am. J. Cardiol. 89:2002;919-923
    • (2002) Am. J. Cardiol. , vol.89 , pp. 919-923
    • Mager, A.1    Battler, A.2    Birnbaum, Y.3    Magal, N.4    Shohat, M.5
  • 20
    • 0035942244 scopus 로고    scopus 로고
    • Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary stenting
    • Kosokabe T., Okumura K., Sone T., et al. Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary stenting. Circulation. 103:2001;2048-2054
    • (2001) Circulation , vol.103 , pp. 2048-2054
    • Kosokabe, T.1    Okumura, K.2    Sone, T.3
  • 21
    • 0033879570 scopus 로고    scopus 로고
    • Homocysteine, lipoprotein(a), and restenosis after percutaneous transluminal coronary angioplasty: A prospective study
    • Miner S.E., Hegele R.A., Sparkes J., et al. Homocysteine, lipoprotein(a), and restenosis after percutaneous transluminal coronary angioplasty: a prospective study. Am. Heart J. 140:2000;272-278
    • (2000) Am. Heart J. , vol.140 , pp. 272-278
    • Miner, S.E.1    Hegele, R.A.2    Sparkes, J.3
  • 22
    • 0031969688 scopus 로고    scopus 로고
    • The high prevalence of thermolabile 5,10-methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD)
    • Abbate R., Sardi I., Pepe G., et al. The high prevalence of thermolabile 5,10-methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD). Thromb. Haemost. 79:1998;727-730
    • (1998) Thromb. Haemost. , vol.79 , pp. 727-730
    • Abbate, R.1    Sardi, I.2    Pepe, G.3
  • 23
    • 0026262262 scopus 로고
    • Determinants of early versus late cardiac death in patients undergoing coronary artery bypass graft surgery
    • Smith L.R., Harrel F.E., Rankin J.S., et al. Determinants of early versus late cardiac death in patients undergoing coronary artery bypass graft surgery. Circulation. 84(Suppl. III):1991;III245-III253
    • (1991) Circulation , vol.84 , Issue.SUPPL. III , pp. 245-III253
    • Smith, L.R.1    Harrel, F.E.2    Rankin, J.S.3
  • 24
    • 0033599973 scopus 로고    scopus 로고
    • Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women
    • Bostom A.G., Silbershatz H., Rosenberg I.H., et al. Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women. Arch. Intern. Med. 159:1999;1077-1080
    • (1999) Arch. Intern. Med. , vol.159 , pp. 1077-1080
    • Bostom, A.G.1    Silbershatz, H.2    Rosenberg, I.H.3
  • 25
    • 0033526594 scopus 로고    scopus 로고
    • Plasma homocysteine and all-cause mortality in diabetes
    • Kark J.D., Selhub J., Bostom A., Adler B., Rosenberg I.H. Plasma homocysteine and all-cause mortality in diabetes. Lancet. 353:1999;1936-1937
    • (1999) Lancet , vol.353 , pp. 1936-1937
    • Kark, J.D.1    Selhub, J.2    Bostom, A.3    Adler, B.4    Rosenberg, I.H.5
  • 26
    • 0034972871 scopus 로고    scopus 로고
    • Plasma total homocysteine and cardiovascular and noncardiovascular mortality: The Hordaland homocysteine study
    • Vollset S.E., Refsum H., Tverdal A., et al. Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland homocysteine study. Am. J. Clin. Nutr. 74:2001;130-136
    • (2001) Am. J. Clin. Nutr. , vol.74 , pp. 130-136
    • Vollset, S.E.1    Refsum, H.2    Tverdal, A.3
  • 27
    • 0035969545 scopus 로고    scopus 로고
    • Decrease rate of coronary restenosis after lowering of plasma homocysteine levels
    • Schnyder G., Roffi M., Pin R., et al. Decrease rate of coronary restenosis after lowering of plasma homocysteine levels. N. Engl. J. Med. 345:2001;1593-1600
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1593-1600
    • Schnyder, G.1    Roffi, M.2    Pin, R.3
  • 28
    • 0035830389 scopus 로고    scopus 로고
    • Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury
    • Morita H., Kurihara H., Yoshida S., et al. Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury. Circulation. 103:2001;133-139
    • (2001) Circulation , vol.103 , pp. 133-139
    • Morita, H.1    Kurihara, H.2    Yoshida, S.3
  • 29
    • 0034906768 scopus 로고    scopus 로고
    • Increasing levels of dietary homocysteine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia
    • Southern F., Eidt J., Drouilhet J., et al. Increasing levels of dietary homocysteine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia. Atherosclerosis. 158:2001;129-138
    • (2001) Atherosclerosis , vol.158 , pp. 129-138
    • Southern, F.1    Eidt, J.2    Drouilhet, J.3
  • 30
    • 0033533527 scopus 로고    scopus 로고
    • Homocyst(e)ine and cardiovascular disease: A critical review of the epidemiologic evidence
    • Eikelboom J.W., Lonn E., Genest J. Jr., Hankey G., Yusuf S. Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann. Intern. Med. 131:1999;363-375
    • (1999) Ann. Intern. Med. , vol.131 , pp. 363-375
    • Eikelboom, J.W.1    Lonn, E.2    Genest Jr., J.3    Hankey, G.4    Yusuf, S.5
  • 31
    • 0034023742 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis - Mechanisms for injury
    • Thambyrajah J., Townend J.N. Homocysteine and atherothrombosis - mechanisms for injury. Eur. Heart J. 21:2000;967-974
    • (2000) Eur. Heart J. , vol.21 , pp. 967-974
    • Thambyrajah, J.1    Townend, J.N.2
  • 32
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocyst(e)inemia
    • Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J. Clin. Invest. 98:1996;5-7
    • (1996) J. Clin. Invest. , vol.98 , pp. 5-7
    • Loscalzo, J.1
  • 33
    • 0035906327 scopus 로고    scopus 로고
    • The role of folic acid and vitamin B12 in genomic stability of human cells
    • Fenech M. The role of folic acid and vitamin B12 in genomic stability of human cells. Mutat. Res. 475:2001;57-67
    • (2001) Mutat. Res. , vol.475 , pp. 57-67
    • Fenech, M.1
  • 34
    • 0034703084 scopus 로고    scopus 로고
    • Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation
    • Yi P., Melnyk S., Pogribna M., Pogribny I.P., Hine R.J., James S.J. Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation. J. Biol. Chem. 275:2000;29318-29323
    • (2000) J. Biol. Chem. , vol.275 , pp. 29318-29323
    • Yi, P.1    Melnyk, S.2    Pogribna, M.3    Pogribny, I.P.4    Hine, R.J.5    James, S.J.6
  • 35
    • 0035282903 scopus 로고    scopus 로고
    • Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
    • Chen Z., Karaplis A.C., Ackerman S.L., et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum. Mol. Genet. 10:2001;433-443
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 433-443
    • Chen, Z.1    Karaplis, A.C.2    Ackerman, S.L.3
  • 36
    • 0033846460 scopus 로고    scopus 로고
    • Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene
    • Stern L.L., Mason J.B., Selhub J., Choi S.W. Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene. Cancer Epidemiol. Biomarkers Prev. 9:2000;849-853
    • (2000) Cancer Epidemiol. Biomarkers Prev. , vol.9 , pp. 849-853
    • Stern, L.L.1    Mason, J.B.2    Selhub, J.3    Choi, S.W.4
  • 37
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • Friso S., Choi S.W., Girelli D., et al. A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc. Natl. Acad. Sci. U. S. A. 99:2002;5606-56011
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 5606-56011
    • Friso, S.1    Choi, S.W.2    Girelli, D.3
  • 38
    • 0033918175 scopus 로고    scopus 로고
    • Genetic instability and atherosclerosis: Can somatic mutations account for the development of cardiovascular diseases?
    • Andreassi M.G., Botto N., Colombo M.G., Biagini A., Clerico A. Genetic instability and atherosclerosis: can somatic mutations account for the development of cardiovascular diseases? Environ. Mol. Mutagen. 35:2000;265-269
    • (2000) Environ. Mol. Mutagen. , vol.35 , pp. 265-269
    • Andreassi, M.G.1    Botto, N.2    Colombo, M.G.3    Biagini, A.4    Clerico, A.5
  • 39
    • 0037221513 scopus 로고    scopus 로고
    • Coronary atherosclerosis and somatic mutations: An overview of the contributive factors for oxidative DNA damage
    • Andreassi M.G. Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage. Mutat. Res. 543:2003;67-86
    • (2003) Mutat. Res. , vol.543 , pp. 67-86
    • Andreassi, M.G.1
  • 40
    • 0035853412 scopus 로고    scopus 로고
    • Reactive oxygen species and death: Oxidative DNA damage in atherosclerosis
    • Bennett M.R. Reactive oxygen species and death: oxidative DNA damage in atherosclerosis. Circ. Res. 88:2001;648-650
    • (2001) Circ. Res. , vol.88 , pp. 648-650
    • Bennett, M.R.1
  • 41
    • 0037019585 scopus 로고    scopus 로고
    • Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty
    • Andreassi M.G., Botto N., Rizza A., et al. Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty. JACC. 40:2002;862-868
    • (2002) JACC , vol.40 , pp. 862-868
    • Andreassi, M.G.1    Botto, N.2    Rizza, A.3
  • 42
    • 0037316039 scopus 로고    scopus 로고
    • Methylentetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease
    • Andreassi M.G., Botto N., Cocci F., et al. Methylentetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease. Hum. Genet. 112:2003;171-177
    • (2003) Hum. Genet. , vol.112 , pp. 171-177
    • Andreassi, M.G.1    Botto, N.2    Cocci, F.3
  • 43
    • 0036998067 scopus 로고    scopus 로고
    • Can screening for genetic markers improve peripheral artery bypass patency?
    • Kibbe M.R., Hasset A.L., McSherry F., et al. Can screening for genetic markers improve peripheral artery bypass patency? J. Vasc. Surg. 36:2002;1198-1206
    • (2002) J. Vasc. Surg. , vol.36 , pp. 1198-1206
    • Kibbe, M.R.1    Hasset, A.L.2    McSherry, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.