메뉴 건너뛰기




Volumn 99, Issue 4, 2008, Pages 816-823

Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CIMETIDINE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DIPHENHYDRAMINE; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN 1; RANITIDINE;

EID: 41349107395     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00744.x     Document Type: Article
Times cited : (104)

References (48)
  • 1
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling VA. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976; 455: 152-62.
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.A.2
  • 2
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O et.al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97: 3473-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 3
    • 18144370731 scopus 로고    scopus 로고
    • Mechanisms of resistance to anticancer drugs: The role of the polymorphic ABC transporters ABCB1 and ABCG2
    • Lepper ER, Nooter K, Verweij J, Acharya MR, Figg WD, Sparreboom A. Mechanisms of resistance to anticancer drugs: The role of the polymorphic ABC transporters ABCB1 and ABCG2. Pharmacogenomics 2005; 6: 115-38.
    • (2005) Pharmacogenomics , vol.6 , pp. 115-138
    • Lepper, E.R.1    Nooter, K.2    Verweij, J.3    Acharya, M.R.4    Figg, W.D.5    Sparreboom, A.6
  • 4
    • 3042767682 scopus 로고    scopus 로고
    • Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1
    • Pauli-Magnus C, Kroetz DL. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharm Res 2004; 21: 904-13.
    • (2004) Pharm Res , vol.21 , pp. 904-913
    • Pauli-Magnus, C.1    Kroetz, D.L.2
  • 5
    • 12444273301 scopus 로고    scopus 로고
    • MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects
    • Morita Y, Sakaeda T, Horinouchi M et.al. MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects. Pharm Res 2003; 20: 552-6.
    • (2003) Pharm Res , vol.20 , pp. 552-556
    • Morita, Y.1    Sakaeda, T.2    Horinouchi, M.3
  • 6
    • 0038106665 scopus 로고    scopus 로고
    • Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs
    • Sakaeda T, Nakamura T, Okumura K. Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs. Pharmacogenomics 2003; 4: 397-410.
    • (2003) Pharmacogenomics , vol.4 , pp. 397-410
    • Sakaeda, T.1    Nakamura, T.2    Okumura, K.3
  • 7
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF et.al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-99.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3
  • 8
    • 0035999902 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
    • Drescher S, Schaeffeler E, Hitzl M et.al. MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine. Br J Clin Pharmacol 2002; 53: 526-34.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 526-534
    • Drescher, S.1    Schaeffeler, E.2    Hitzl, M.3
  • 9
    • 7944236606 scopus 로고    scopus 로고
    • A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
    • Yi SY, Hong KS, Lim HS et.al. A variant 2677A allele of the MDR1 gene affects fexofenadine disposition. Clin Pharmacol Ther 2004; 76: 418-27.
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 418-427
    • Yi, S.Y.1    Hong, K.S.2    Lim, H.S.3
  • 10
    • 18144399975 scopus 로고    scopus 로고
    • Clinical pharmacogenetics of immunosuppressive drugs in organ transplantation
    • Szekeres T, Haushofer A. Clinical pharmacogenetics of immunosuppressive drugs in organ transplantation. Pharmacogenomics 2005; 6: 163-8.
    • (2005) Pharmacogenomics , vol.6 , pp. 163-168
    • Szekeres, T.1    Haushofer, A.2
  • 11
    • 21444449731 scopus 로고    scopus 로고
    • ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation
    • Hauser IA, Schaeffeler E, Gauer S et.al. ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation. J Am Soc Nephrol 2005; 16: 1501-11.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1501-1511
    • Hauser, I.A.1    Schaeffeler, E.2    Gauer, S.3
  • 12
    • 33749989048 scopus 로고    scopus 로고
    • MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells
    • Salama NN, Yang Z, Bui T, Ho RJ. MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells. J Pharm Sci 2006; 95: 2293-308.
    • (2006) J Pharm Sci , vol.95 , pp. 2293-2308
    • Salama, N.N.1    Yang, Z.2    Bui, T.3    Ho, R.J.4
  • 13
    • 3042600927 scopus 로고    scopus 로고
    • Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms
    • Meissner K, Jedlitschky G, Meyer zu Schwabedissen H et.al. Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms. Pharmacogenetics 2004; 14: 381-5.
    • (2004) Pharmacogenetics , vol.14 , pp. 381-385
    • Meissner, K.1    Jedlitschky, G.2    Meyer zu Schwabedissen, H.3
  • 14
    • 11144358432 scopus 로고    scopus 로고
    • CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation
    • Anglicheau D, Thervet E, Etienne I et.al. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation. Clin Pharmacol Ther 2004; 75: 422-33.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 422-433
    • Anglicheau, D.1    Thervet, E.2    Etienne, I.3
  • 15
    • 0037330517 scopus 로고    scopus 로고
    • Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
    • Chowbay B, Cumaraswamy S, Cheung YB, Zhou Q, Lee EJ. Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients. Pharmacogenetics 2003; 13: 89-95.
    • (2003) Pharmacogenetics , vol.13 , pp. 89-95
    • Chowbay, B.1    Cumaraswamy, S.2    Cheung, Y.B.3    Zhou, Q.4    Lee, E.J.5
  • 16
    • 10744222684 scopus 로고    scopus 로고
    • Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
    • Kroetz DL, Pauli-Magnus C, Hodges LM et.al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics 2003; 13: 481-94.
    • (2003) Pharmacogenetics , vol.13 , pp. 481-494
    • Kroetz, D.L.1    Pauli-Magnus, C.2    Hodges, L.M.3
  • 17
    • 0036881149 scopus 로고    scopus 로고
    • Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
    • Johne A, Köpke K, Gerloff T et.al. Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene. Clin Pharmacol Ther 2002; 72: 584-94.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 584-594
    • Johne, A.1    Köpke, K.2    Gerloff, T.3
  • 18
    • 0036693051 scopus 로고    scopus 로고
    • Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
    • Kurata Y, Ieiri I, Kimura M et.al. Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein. Clin Pharmacol Ther 2002; 72: 209-19.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 209-219
    • Kurata, Y.1    Ieiri, I.2    Kimura, M.3
  • 19
    • 11344272181 scopus 로고    scopus 로고
    • Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer
    • Wong M, Evans S, Rivory LP et.al. Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer. Clin Pharmacol Ther 2005; 77: 33-42.
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 33-42
    • Wong, M.1    Evans, S.2    Rivory, L.P.3
  • 20
    • 0035870289 scopus 로고    scopus 로고
    • Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
    • Maliepaard M, Scheffer GL, Faneyte IF et.al. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res 2001; 61: 3458-64.
    • (2001) Cancer Res , vol.61 , pp. 3458-3464
    • Maliepaard, M.1    Scheffer, G.L.2    Faneyte, I.F.3
  • 21
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD et.al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001; 7: 1028-34.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3
  • 22
    • 0032895533 scopus 로고    scopus 로고
    • Molecular cloning of cDNAs which is highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes
    • Miyake K, Mickley L, Litman T et.al. Molecular cloning of cDNAs which is highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes. Cancer Res 1999; 59: 8-13.
    • (1999) Cancer Res , vol.59 , pp. 8-13
    • Miyake, K.1    Mickley, L.2    Litman, T.3
  • 23
    • 0034817098 scopus 로고    scopus 로고
    • Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells
    • Kawabata S, Oka M, Shiozawa K et.al. Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. Biochem Biophys Res Commun 2001; 280: 1216-23.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 1216-1223
    • Kawabata, S.1    Oka, M.2    Shiozawa, K.3
  • 24
    • 0037218382 scopus 로고    scopus 로고
    • Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors
    • Wang X, Furukawa T, Nitanda T et.al. Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors. Mol Pharmacol 2003; 63: 65-72.
    • (2003) Mol Pharmacol , vol.63 , pp. 65-72
    • Wang, X.1    Furukawa, T.2    Nitanda, T.3
  • 25
    • 0036598543 scopus 로고    scopus 로고
    • C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance
    • Imai Y, Nakane M, Kage K et.al. C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther 2002; 1: 611-6.
    • (2002) Mol Cancer Ther , vol.1 , pp. 611-616
    • Imai, Y.1    Nakane, M.2    Kage, K.3
  • 26
    • 3042651340 scopus 로고    scopus 로고
    • Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype
    • Sparreboom A, Gelderblom H, Marsh S et.al. Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype. Clin Pharmacol Ther 2004; 76: 38-44.
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 38-44
    • Sparreboom, A.1    Gelderblom, H.2    Marsh, S.3
  • 27
    • 17144413348 scopus 로고    scopus 로고
    • Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer
    • Zhou Q, Sparreboom A, Tan EH et.al. Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer. Br J Clin Pharmacol 2005; 59: 415-24.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 415-424
    • Zhou, Q.1    Sparreboom, A.2    Tan, E.H.3
  • 28
    • 0037038407 scopus 로고    scopus 로고
    • Determination of doxorubicin and its metabolites in rat serum and bile by LC: Application to preclinical pharmacokinetic studies
    • Zhou Q, Chowbay B. Determination of doxorubicin and its metabolites in rat serum and bile by LC: Application to preclinical pharmacokinetic studies. J Pharm Biomed Anal 2002; 30: 1063-74.
    • (2002) J Pharm Biomed Anal , vol.30 , pp. 1063-1074
    • Zhou, Q.1    Chowbay, B.2
  • 30
    • 34547788826 scopus 로고    scopus 로고
    • Role of UGT1A1*6, UGT1A1*28 and ABCG2 c. 421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients
    • Jada SR, Lim R, Wong CI et.al. Role of UGT1A1*6, UGT1A1*28 and ABCG2 c. 421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients. Cancer Sci 2007; 98: 1461-7.
    • (2007) Cancer Sci , vol.98 , pp. 1461-1467
    • Jada, S.R.1    Lim, R.2    Wong, C.I.3
  • 31
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C4T affects mRNA stability
    • Wang D, Johnson AD, Papp AC, Kroetz DL, Sadee W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C4T affects mRNA stability. Pharmacogenet Genomics 2005; 15: 693-704.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 693-704
    • Wang, D.1    Johnson, A.D.2    Papp, A.C.3    Kroetz, D.L.4    Sadee, W.5
  • 32
    • 0024362996 scopus 로고
    • P-glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance
    • Kioka N, Tsubota J, Kakehi Y et.al. P-glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance. Biochem Biophys Res Commun 1989; 162: 224-31.
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 224-231
    • Kioka, N.1    Tsubota, J.2    Kakehi, Y.3
  • 33
    • 0036731995 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
    • Illmer T, Schuler US, Thiede C et.al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62: 4955-62.
    • (2002) Cancer Res , vol.62 , pp. 4955-4962
    • Illmer, T.1    Schuler, U.S.2    Thiede, C.3
  • 34
    • 33846504706 scopus 로고    scopus 로고
    • A 'silent' polymorphism in the MDR1 gene changes substrate specificity
    • Kimchi-Sarfaty C, Oh JM, Kim IW et.al. A 'silent' polymorphism in the MDR1 gene changes substrate specificity. Science 2007; 315: 525-8.
    • (2007) Science , vol.315 , pp. 525-528
    • Kimchi-Sarfaty, C.1    Oh, J.M.2    Kim, I.W.3
  • 35
    • 12144286615 scopus 로고    scopus 로고
    • Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan
    • Sai K, Kaniwa N, Itoda M et.al. Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan. Pharmacogenetics 2003; 13: 741-57.
    • (2003) Pharmacogenetics , vol.13 , pp. 741-757
    • Sai, K.1    Kaniwa, N.2    Itoda, M.3
  • 36
    • 41349119954 scopus 로고    scopus 로고
    • Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism
    • October 9: [Epub ahead of print]
    • Rodríguez-Antona C, Niemi M, Backman JT et.al. Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism. Pharmacogenomics J 2007 October 9: [Epub ahead of print].
    • (2007) Pharmacogenomics J
    • Rodríguez-Antona, C.1    Niemi, M.2    Backman, J.T.3
  • 37
    • 19944399722 scopus 로고    scopus 로고
    • Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta
    • Kobayashi D, Ieiri I, Hirota T et.al. Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta. Drug Metab Dispos 2005; 33: 94-101.
    • (2005) Drug Metab Dispos , vol.33 , pp. 94-101
    • Kobayashi, D.1    Ieiri, I.2    Hirota, T.3
  • 38
    • 4444381535 scopus 로고    scopus 로고
    • ABCG2 pharmacogenetics: Ethnic differences in allele frequency and assessment of influence on irinotecan disposition
    • de Jong FA, Marsh S, Mathijssen RH et.al. ABCG2 pharmacogenetics: Ethnic differences in allele frequency and assessment of influence on irinotecan disposition. Clin Cancer Res 2004; 10: 5889-94.
    • (2004) Clin Cancer Res , vol.10 , pp. 5889-5894
    • de Jong, F.A.1    Marsh, S.2    Mathijssen, R.H.3
  • 39
    • 34250825286 scopus 로고    scopus 로고
    • Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer
    • Han JY, Lim HS, Yoo YK et.al. Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. Cancer 2007; 110: 138-47.
    • (2007) Cancer , vol.110 , pp. 138-147
    • Han, J.Y.1    Lim, H.S.2    Yoo, Y.K.3
  • 40
    • 34250644339 scopus 로고    scopus 로고
    • Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients
    • Lal S, Wong ZW, Jada SR et.al. Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients. Pharmacogenomics 2007; 6: 567-75.
    • (2007) Pharmacogenomics , vol.6 , pp. 567-575
    • Lal, S.1    Wong, Z.W.2    Jada, S.R.3
  • 41
    • 20144364789 scopus 로고    scopus 로고
    • ABCB5 -mediated doxorubicin transport and chemoresistance in human malignant melanoma
    • Frank NY, Margaryan A, Huang Y et.al. ABCB5 -mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res 2005; 65: 4320-33.
    • (2005) Cancer Res , vol.65 , pp. 4320-4333
    • Frank, N.Y.1    Margaryan, A.2    Huang, Y.3
  • 42
    • 20044383925 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
    • Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry W 3rd, Dantzig AH. The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 2005; 4: 855-63.
    • (2005) Mol Cancer Ther , vol.4 , pp. 855-863
    • Pratt, S.1    Shepard, R.L.2    Kandasamy, R.A.3    Johnston, P.A.4    Perry III, W.5    Dantzig, A.H.6
  • 43
    • 0034622633 scopus 로고    scopus 로고
    • Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin
    • Awasthi S, Cheng J, Singhal SS et.al. Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin. Biochemistry 2000; 39: 9327-34.
    • (2000) Biochemistry , vol.39 , pp. 9327-9334
    • Awasthi, S.1    Cheng, J.2    Singhal, S.S.3
  • 44
    • 0028081258 scopus 로고
    • Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells
    • Slapak CA, Mizunuma N, Kufe DW. Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells. Blood 1994; 84: 3113-21.
    • (1994) Blood , vol.84 , pp. 3113-3121
    • Slapak, C.A.1    Mizunuma, N.2    Kufe, D.W.3
  • 45
    • 0035918322 scopus 로고    scopus 로고
    • Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines
    • Zhang DW, Cole SP, Deeley RG. Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines. J Biol Chem 2001; 276: 13231-9.
    • (2001) J Biol Chem , vol.276 , pp. 13231-13239
    • Zhang, D.W.1    Cole, S.P.2    Deeley, R.G.3
  • 46
    • 0017258828 scopus 로고
    • Adriamycin metabolism in man. Evidence from urinary metabolites
    • Takanashi S, Bachur NR. Adriamycin metabolism in man. Evidence from urinary metabolites. Drug Metab Dispos 1976; 4: 79-87.
    • (1976) Drug Metab Dispos , vol.4 , pp. 79-87
    • Takanashi, S.1    Bachur, N.R.2
  • 47
    • 34249009348 scopus 로고    scopus 로고
    • A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity
    • Gonzalez-Covarrubias V, Ghosh D, Lakhman SS, Pendyala L, Blanco JG. A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug Metab Dispos 2007; 35: 973-80.
    • (2007) Drug Metab Dispos , vol.35 , pp. 973-980
    • Gonzalez-Covarrubias, V.1    Ghosh, D.2    Lakhman, S.S.3    Pendyala, L.4    Blanco, J.G.5
  • 48
    • 13544253732 scopus 로고    scopus 로고
    • Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3)
    • Lakhman SS, Ghosh D, Blanco JG. Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3). Drug Metab Dispos 2005; 33: 254-7.
    • (2005) Drug Metab Dispos , vol.33 , pp. 254-257
    • Lakhman, S.S.1    Ghosh, D.2    Blanco, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.