Dexamethasone exposure of neonatal rats modulates biliary lipid secretion and hepatic expression of genes controlling bile acid metabolism in adulthood without interfering with primary bile acid kinetics

Pediatric Research

Volumn 63, Issue 4, 2008, Pages 375-381

  Liu, Yan ^a   Havinga, Rick ^a   Van Der Leij, Feike R ^a,b   Boverhof, Renze ^a   Sauer, Pieter J J ^a   Kuipers, Folkert ^a   Stellaard, Frans ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Unit Life Sciences   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; DEXAMETHASONE; MESSENGER RNA; PROTEIN BSEP; PROTEIN NTCP; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE ACID METABOLISM; BILE ACID SYNTHESIS; BILE SECRETION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; LIPID BILE LEVEL; LIVER; MALE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; ANIMALS, NEWBORN; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLIC ACID; CYTOCHROME P-450 CYP27A1; DEXAMETHASONE; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOCORTICOIDS; LIPIDS; LIVER; MALE; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; PREGNANCY; RNA, MESSENGER; STEROID 12-ALPHA-HYDROXYLASE; SYMPORTERS;

EID: 41349089776     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e318165b8af     Document Type: Article

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