Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells

European Journal of Pharmacology

Volumn 584, Issue 2-3, 2008, Pages 229-236

  Ryhänen, Tuomas ^a   Mannermaa, Eliisa ^a   Oksala, Niku ^c   Viiri, Johanna ^a   Paimela, Tuomas ^a   Salminen, Antero ^a   Atalay, Mustafa ^a   Kaarniranta, Kai ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Geldanamycin; Heat shock protein; Oxidative stress; Radicicol; Retinal pigment epithelium

Indexed keywords

GELDANAMYCIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; RADICICOL;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

BENZOQUINONES; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MACROLIDES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; OXIDATIVE STRESS; PIGMENT EPITHELIUM OF EYE; PROTEIN CARBONYLATION; PROTEIN KINASE INHIBITORS; TIME FACTORS;

EID: 41249091413     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.02.010     Document Type: Article

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