A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia

Journal of Clinical Investigation

Volumn 117, Issue 9, 2007, Pages 2611-2620

  Steidl, Ulrich ^a   Steidl, Christian ^b,c   Ebralidze, Alexander ^a   Chapuy, Björn ^b   Han, Hye Jung ^d   Will, Britta ^a,e   Rosenbauer, Frank ^a,f   Becker, Annegret ^b   Wagner, Katharina ^a,g   Koschmieder, Steffen ^a,h   Kobayashi, Susumu ^a   Costa, Daniel B ^a   Schulz, Thomas ^b   O'Brien, Karen B ^a   Verhaak, Roel G W ⁱ   Delwel, Ruud ⁱ   Haase, Detlef ^b   Trümper, Lorenz ^b   Krauter, Jürgen ^g   Kohwi Shigematsu, Terumi ^d   Griesinger, Frank ^b   Tenen, Daniel G ^a,j   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e UNIVERSITY OF FREIBURG   (Germany)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h UNIVERSITY HOSPITAL MÜNSTER   (Germany)

ⁱ ERASMUS MEDICAL CENTER   (Netherlands)

^j HARVARD INSTITUTES OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; PROTEIN SATB1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; COLONY FORMING UNIT GM; CONTROLLED STUDY; ERYTHROCYTE; GENE CONTROL; GENE MUTATION; GENE OVEREXPRESSION; HOMOZYGOSITY; HUMAN; HUMAN CELL; KARYOTYPE; MEGAKARYOCYTE; MYELOID PROGENITOR CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; BASE SEQUENCE; CELL ADHESION MOLECULES, NEURONAL; CELL LINE, TUMOR; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS; RECEPTORS, LYMPHOCYTE HOMING; STEM CELLS; TRANS-ACTIVATORS;

EID: 34848850741     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI30525     Document Type: Article

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