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Volumn 68, Issue 8, 2004, Pages 1507-1514

The GABA-glutamate connection in schizophrenia: Which is the proximate cause?

Author keywords

d Serine; GABA; Glutamate; Glycine B receptor; NMDA receptor; Schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; CARRIER PROTEIN; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 4644228386     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.07.034     Document Type: Note
Times cited : (169)

References (88)
  • 1
    • 0019462450 scopus 로고
    • Dopamine receptors, neuuroleptics, and schizophrenia
    • S.H. Snyder Dopamine receptors, neuuroleptics, and schizophrenia Am J Psychiatr 138 1981 460 464
    • (1981) Am J Psychiatr , vol.138 , pp. 460-464
    • Snyder, S.H.1
  • 2
    • 0023883767 scopus 로고
    • Deficit and nondeficit forms of schizophrenia: The concept
    • W.T. Carpenter Jr., D.W. Heinrichs, and A.M. Wagman Deficit and nondeficit forms of schizophrenia: the concept Am J Psychiatr 145 1988 578 583
    • (1988) Am J Psychiatr , vol.145 , pp. 578-583
    • Carpenter Jr., W.T.1    Heinrichs, D.W.2    Wagman, A.M.3
  • 3
    • 10744221335 scopus 로고    scopus 로고
    • Early and late neurodevelopmental influences in the prodrome to schizophrenia: Contributions of genes, environment, and their interactions
    • T.D. Cannon, T.G. van Erp, C.E. Bearden, R. Loewy, P. Thompson, and A.W. Toga Early and late neurodevelopmental influences in the prodrome to schizophrenia: contributions of genes, environment, and their interactions Schizophr Bull 29 2003 653 669
    • (2003) Schizophr Bull , vol.29 , pp. 653-669
    • Cannon, T.D.1    Van Erp, T.G.2    Bearden, C.E.3    Loewy, R.4    Thompson, P.5    Toga, A.W.6
  • 6
    • 0037308528 scopus 로고    scopus 로고
    • Genes for schizophrenia? Recent findings and their pathophysiological implications
    • P.J. Harrison, and M.J. Owen Genes for schizophrenia? Recent findings and their pathophysiological implications Lancet 61 2003 417 419
    • (2003) Lancet , vol.61 , pp. 417-419
    • Harrison, P.J.1    Owen, M.J.2
  • 8
    • 0018287816 scopus 로고
    • Differential effects of agonal status on measurements of GABA and glutamate decarboxylase in human post-mortem brain tissue from control and Huntington's chorea subjects
    • E.G. Spokes, N.J. Garrett, and L.L. Iversen Differential effects of agonal status on measurements of GABA and glutamate decarboxylase in human post-mortem brain tissue from control and Huntington's chorea subjects J Neurochem. 33 1979 773 778
    • (1979) J Neurochem. , vol.33 , pp. 773-778
    • Spokes, E.G.1    Garrett, N.J.2    Iversen, L.L.3
  • 9
    • 0018373509 scopus 로고
    • Gamma-aminobutyric acid in the brain in schizophrenia
    • A.J. Cross, T.J. Crow, and F. Woen Gamma-aminobutyric acid in the brain in schizophrenia Lancet 1 1979 560 561
    • (1979) Lancet , vol.1 , pp. 560-561
    • Cross, A.J.1    Crow, T.J.2    Woen, F.3
  • 10
    • 3142726152 scopus 로고    scopus 로고
    • Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: A novel target for the treatment of working memory dysfunction
    • D.A. Lewis, D.W. Volk, and T. Hashimoto Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction Psychopharmacology 174 2003 143 150
    • (2003) Psychopharmacology , vol.174 , pp. 143-150
    • Lewis, D.A.1    Volk, D.W.2    Hashimoto, T.3
  • 11
    • 0031595945 scopus 로고    scopus 로고
    • Distribution of glutamate decarboxylase65 immunoreactive puncta on pyramidal and nonpyramidal neurons in hippocampus of schizophrenic brain
    • M.S. Todtenkopf, and F.M. Benes Distribution of glutamate decarboxylase65 immunoreactive puncta on pyramidal and nonpyramidal neurons in hippocampus of schizophrenic brain Synapse 29 1998 323 332
    • (1998) Synapse , vol.29 , pp. 323-332
    • Todtenkopf, M.S.1    Benes, F.M.2
  • 12
    • 0028948389 scopus 로고
    • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
    • S. Akbarian, J.J. Kim, S.G. Potkin, J.O. Hagman, A. Tafazzoli, and W.E. Bunney Jr. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics Arch Gen Psychiatr 52 1995 258 266
    • (1995) Arch Gen Psychiatr , vol.52 , pp. 258-266
    • Akbarian, S.1    Kim, J.J.2    Potkin, S.G.3    Hagman, J.O.4    Tafazzoli, A.5    Bunney Jr., W.E.6
  • 13
    • 0034011252 scopus 로고    scopus 로고
    • Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia
    • D.W. Volk, M.C. Austin, J.N. Pierri, A.R. Sampson, and D.A. Lewis Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia Arch Gen Psychiatr 57 2000 237 245
    • (2000) Arch Gen Psychiatr , vol.57 , pp. 237-245
    • Volk, D.W.1    Austin, M.C.2    Pierri, J.N.3    Sampson, A.R.4    Lewis, D.A.5
  • 14
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • K. Mimics, F.A. Middleton, A. Marquez, D.A. Lewis, and P. Levitt Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex Neuron 28 2000 53 67
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mimics, K.1    Middleton, F.A.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 15
    • 0033759439 scopus 로고    scopus 로고
    • Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: A postmortem brain study
    • A. Guidotti, J. Auta, J.M. Davis, V. Di-Giorgi-Gerevini, Y. Dwivedi, and D.R. Grayson Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study Arch Gen Psychiatr 57 2000 1061 1069
    • (2000) Arch Gen Psychiatr , vol.57 , pp. 1061-1069
    • Guidotti, A.1    Auta, J.2    Davis, J.M.3    Di-Giorgi-Gerevini, V.4    Dwivedi, Y.5    Grayson, D.R.6
  • 16
    • 0036843296 scopus 로고    scopus 로고
    • Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: A preliminary study
    • M.P. Vawter, J.M. Crook, T.M. Hyde, J.E. Kleinman, D.R. Weinberger, and K.G. Becker Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study Schizophr Res. 58 2002 11 20
    • (2002) Schizophr Res. , vol.58 , pp. 11-20
    • Vawter, M.P.1    Crook, J.M.2    Hyde, T.M.3    Kleinman, J.E.4    Weinberger, D.R.5    Becker, K.G.6
  • 17
    • 0037705995 scopus 로고    scopus 로고
    • Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia
    • T. Hashimoto, D.W. Volk, S.M. Eggan, K. Mimics, J.N. Pierri, and Z. Sun Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia J Neurosci. 16 2003 6315 6326
    • (2003) J Neurosci. , vol.16 , pp. 6315-6326
    • Hashimoto, T.1    Volk, D.W.2    Eggan, S.M.3    Mimics, K.4    Pierri, J.N.5    Sun, Z.6
  • 18
    • 0025208187 scopus 로고
    • Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia
    • G.P. Reynolds, C. Czudek, and H.B. Andrews Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia Biol Psychiatr 27 1990 1038 1044
    • (1990) Biol Psychiatr , vol.27 , pp. 1038-1044
    • Reynolds, G.P.1    Czudek, C.2    Andrews, H.B.3
  • 20
    • 0032530782 scopus 로고    scopus 로고
    • Comparison of gl7utamate and gamma-aminobutyric acid uptake binding sites in frontal and temporal lobes in schizophrenia
    • M.D. Simpson, P. Slater, and J.F. Deakin Comparison of gl7utamate and gamma-aminobutyric acid uptake binding sites in frontal and temporal lobes in schizophrenia Biol Psychiatr 44 1998 423 427
    • (1998) Biol Psychiatr , vol.44 , pp. 423-427
    • Simpson, M.D.1    Slater, P.2    Deakin, J.F.3
  • 21
    • 0035140656 scopus 로고    scopus 로고
    • GABA transporter-1 mRNA in prefrontal cortex in schizophrenia: Decreased expression in a subset of neurons
    • D.W. Volk, M.C. Austin, J.N. Pierri, A.R. Sampson, and D.A. Lewis GABA transporter-1 mRNA in prefrontal cortex in schizophrenia: decreased expression in a subset of neurons Am J Psychiatr 158 2001 256 265
    • (2001) Am J Psychiatr , vol.158 , pp. 256-265
    • Volk, D.W.1    Austin, M.C.2    Pierri, J.N.3    Sampson, A.R.4    Lewis, D.A.5
  • 22
    • 0032574841 scopus 로고    scopus 로고
    • A subclass of prefrontal gama-aminobutyric acid axon terminals are selectively altered in schizophrenia
    • T.U. Woo, R.E. Whitehead, D.S. Melchitzky, and D.A. Lewis A subclass of prefrontal gama-aminobutyric acid axon terminals are selectively altered in schizophrenia Proc Natl Acad Sci USA 28 1998 5341 5346
    • (1998) Proc Natl Acad Sci USA , vol.28 , pp. 5341-5346
    • Woo, T.U.1    Whitehead, R.E.2    Melchitzky, D.S.3    Lewis, D.A.4
  • 23
    • 0036784474 scopus 로고    scopus 로고
    • Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cells inputs to pyramidal neurons in schizophrenia
    • D.W. Volk, J.N. Pierri, J.M. Fritschy, S. Auh, A.R. Sampson, and D.A. Lewis Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cells inputs to pyramidal neurons in schizophrenia Cereb Cortex 12 2002 1063 1070
    • (2002) Cereb Cortex , vol.12 , pp. 1063-1070
    • Volk, D.W.1    Pierri, J.N.2    Fritschy, J.M.3    Auh, S.4    Sampson, A.R.5    Lewis, D.A.6
  • 24
    • 0023162690 scopus 로고
    • 3H]Muscimol binding sites increased in autopsied brains of chronic schizophrenics
    • 3H]Muscimol binding sites increased in autopsied brains of chronic schizophrenics Life Sci. 40 1987 259 266
    • (1987) Life Sci. , vol.40 , pp. 259-266
    • Hanada, S.1    Mita, T.2    Nishino, N.3    Tanaka, C.4
  • 25
    • 0030331175 scopus 로고    scopus 로고
    • Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects
    • F.M. Benes, S.L. Vincent, A. Marie, and Y. Khan Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects Neuroscience 75 1996 1021 1031
    • (1996) Neuroscience , vol.75 , pp. 1021-1031
    • Benes, F.M.1    Vincent, S.L.2    Marie, A.3    Khan, Y.4
  • 26
    • 0030007814 scopus 로고    scopus 로고
    • Differences in the subregional and cellular distribution of GABAA receptor binding in the hippocampal formation of schizophrenic brain
    • F.M. Benes, Y. Khan, S.L. Vincent, and R. Wickramasinghe Differences in the subregional and cellular distribution of GABAA receptor binding in the hippocampal formation of schizophrenic brain Synapse 22 1996 338 439
    • (1996) Synapse , vol.22 , pp. 338-439
    • Benes, F.M.1    Khan, Y.2    Vincent, S.L.3    Wickramasinghe, R.4
  • 27
    • 0032586747 scopus 로고    scopus 로고
    • Changes in serotonin2A and GABA(A) receptors in schizophrenia: Studies on the human dorsolateral prefrontal cortex
    • B. Dean, T. Hussain, W. Hayes, E. Scarr, S. Kitsoulis, and C. Hill Changes in serotonin2A and GABA(A) receptors in schizophrenia: studies on the human dorsolateral prefrontal cortex J Neurochem. 72 1999 1593 1599
    • (1999) J Neurochem. , vol.72 , pp. 1593-1599
    • Dean, B.1    Hussain, T.2    Hayes, W.3    Scarr, E.4    Kitsoulis, S.5    Hill, C.6
  • 28
    • 0030994817 scopus 로고    scopus 로고
    • Uncoupling of GABA(A) and benzodiazepine receptor binding activity in the hippocampal formation of schizophrenic brain
    • F.M. Benes, R. Wickramasinghe, S.L. Vincent, Y. Khan, and M. Todtenkopf Uncoupling of GABA(A) and benzodiazepine receptor binding activity in the hippocampal formation of schizophrenic brain Brain Res 755 1997 121 129
    • (1997) Brain Res , vol.755 , pp. 121-129
    • Benes, F.M.1    Wickramasinghe, R.2    Vincent, S.L.3    Khan, Y.4    Todtenkopf, M.5
  • 30
    • 0027405968 scopus 로고
    • Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development
    • S. Akbarian, A. Vinuela, J.J. Kim, S.G. Potkin, W.E. Bunney Jr., and E.G. Jones Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development Arch Gen Psychiatr 50 1993 178 187
    • (1993) Arch Gen Psychiatr , vol.50 , pp. 178-187
    • Akbarian, S.1    Vinuela, A.2    Kim, J.J.3    Potkin, S.G.4    Bunney Jr., W.E.5    Jones, E.G.6
  • 31
    • 0037163433 scopus 로고    scopus 로고
    • In Patas monkey, glutamic acid decarobxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas
    • M.A. Rodriguez, H.J. Caruncho, E. Costa, C. Pesold, W.S. Liu, and A. Guidotti In Patas monkey, glutamic acid decarobxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas J Comp Neurol. 451 2002 279 288
    • (2002) J Comp Neurol. , vol.451 , pp. 279-288
    • Rodriguez, M.A.1    Caruncho, H.J.2    Costa, E.3    Pesold, C.4    Liu, W.S.5    Guidotti, A.6
  • 32
    • 0033646608 scopus 로고    scopus 로고
    • Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression
    • S.H. Fatemi, J.A. Earle, and T. McMenomy Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression Mol Psychiatr 5 2000 654 663
    • (2000) Mol Psychiatr , vol.5 , pp. 654-663
    • Fatemi, S.H.1    Earle, J.A.2    McMenomy, T.3
  • 33
    • 3042696847 scopus 로고    scopus 로고
    • Molecular abnormalities of the hippocampus in severe psychiatric illness: Postmortem findings from the Stanley neuropathology Consortium
    • M.B. Knable, B.M. Bard, M.J. Webster, J. Meador-woodruff, and E.F. Torrey Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley neuropathology Consortium Mol Psychiatr 9 2004 609 620
    • (2004) Mol Psychiatr , vol.9 , pp. 609-620
    • Knable, M.B.1    Bard, B.M.2    Webster, M.J.3    Meador-Woodruff, J.4    Torrey, E.F.5
  • 34
    • 0042329918 scopus 로고    scopus 로고
    • Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: Towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis
    • S.L. Eastsood, and P.J. Harrison Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis Mol Psychiatr 8 2003 821 831
    • (2003) Mol Psychiatr , vol.8 , pp. 821-831
    • Eastsood, S.L.1    Harrison, P.J.2
  • 35
    • 0035968886 scopus 로고    scopus 로고
    • Altered levels of Reelin and its isoforms in schizophrenia and mood disorders
    • S.H. Fatemi, J.L. Kroll, and J.M. Stary Altered levels of Reelin and its isoforms in schizophrenia and mood disorders Neuroreport 12 2001 3209 3215
    • (2001) Neuroreport , vol.12 , pp. 3209-3215
    • Fatemi, S.H.1    Kroll, J.L.2    Stary, J.M.3
  • 36
    • 0036844074 scopus 로고    scopus 로고
    • Association analysis of polymorphic CGG repeat in 5′ UT‰ of the reelin and VLDLR genes with schizophrenia
    • A. Akahane, H. Kunugi, H. Tanaka, and S. Nanko Association analysis of polymorphic CGG repeat in 5′ UT‰ of the reelin and VLDLR genes with schizophrenia Schizophr Res. 58 2002 37 41
    • (2002) Schizophr Res. , vol.58 , pp. 37-41
    • Akahane, A.1    Kunugi, H.2    Tanaka, H.3    Nanko, S.4
  • 37
    • 0025855720 scopus 로고
    • Benzodiazepines in the treatment of schizophrenia: A review and reappraisal
    • O.M. Wolkowitz, and D. Pickar Benzodiazepines in the treatment of schizophrenia: a review and reappraisal Am J Psychiatr 148 1991 714 726
    • (1991) Am J Psychiatr , vol.148 , pp. 714-726
    • Wolkowitz, O.M.1    Pickar, D.2
  • 39
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • D.C. Javitt, and S.R. Zukin Recent advances in the phencyclidine model of schizophrenia Am J Psychiatr 148 1991 1301 1308
    • (1991) Am J Psychiatr , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 42
    • 0030861444 scopus 로고    scopus 로고
    • Clozapine blunts N-methyl-d-aspartate antagonist-induced psychosis: A study with ketamine
    • A.K. Malhortra, C.M. Adler, S.D. Kennison, I. Elman, D. Pickar, and A. Breier Clozapine blunts N-methyl-d-aspartate antagonist-induced psychosis: a study with ketamine Biol Psychiatr 42 1997 664 668
    • (1997) Biol Psychiatr , vol.42 , pp. 664-668
    • Malhortra, A.K.1    Adler, C.M.2    Kennison, S.D.3    Elman, I.4    Pickar, D.5    Breier, A.6
  • 43
    • 0036711792 scopus 로고    scopus 로고
    • Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia
    • M.T. Avila, M.A. Weiler, A.C. Lahti, C.A. Tamminga, and G.K. Thaker Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia Am J Psychiatr 159 2002 1490 1496
    • (2002) Am J Psychiatr , vol.159 , pp. 1490-1496
    • Avila, M.T.1    Weiler, M.A.2    Lahti, A.C.3    Tamminga, C.A.4    Thaker, G.K.5
  • 44
    • 0033988526 scopus 로고    scopus 로고
    • Effects of 9S-ketamine on striatal dopamine: A [11C] raclopride PET study of a model psychosis in humans
    • F.X. Vollenweider, P. Vontobel, I. Oye, D. Hell, and K.L. Leenders Effects of 9S-ketamine on striatal dopamine: a [11C] raclopride PET study of a model psychosis in humans J Psychiatr Res. 34 2000 35 43
    • (2000) J Psychiatr Res. , vol.34 , pp. 35-43
    • Vollenweider, F.X.1    Vontobel, P.2    Oye, I.3    Hell, D.4    Leenders, K.L.5
  • 45
    • 0036132260 scopus 로고    scopus 로고
    • NMDA antagonist effects on striatal dopamine release: Positron emission tomography studies in humans
    • L.S. Kegeles, D. Martinez, L.D. Kochan, D.R. Hwang, Y. Huang, and O. Mawlawi NMDA antagonist effects on striatal dopamine release: positron emission tomography studies in humans Synapse 43 2002 19 29
    • (2002) Synapse , vol.43 , pp. 19-29
    • Kegeles, L.S.1    Martinez, D.2    Kochan, L.D.3    Hwang, D.R.4    Huang, Y.5    Mawlawi, O.6
  • 46
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • D.L. Braff, M.A. Geyer, and N.R. Swerdlow Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies Psychophannacology 156 2001 234 258
    • (2001) Psychophannacology , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 47
    • 0036501435 scopus 로고    scopus 로고
    • Mismatch negativity predicts psychotic experiences induced by NMDA receptor antagonist in healthy volunteers
    • D. Umbricht, R. Roller, F.X. Vollenweider, and L. Schmid Mismatch negativity predicts psychotic experiences induced by NMDA receptor antagonist in healthy volunteers Biol Psychiatr 1 2002 400 406
    • (2002) Biol Psychiatr , vol.1 , pp. 400-406
    • Umbricht, D.1    Roller, R.2    Vollenweider, F.X.3    Schmid, L.4
  • 48
    • 3142737856 scopus 로고    scopus 로고
    • The NMDA receptor glycine modulatory site: A therapeutic target for improving cognition and reducing negative symptoms in schizophrenia
    • J.T. Coyle, and G. Tsai The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia Psychopharmacology 174 2004 32 38
    • (2004) Psychopharmacology , vol.174 , pp. 32-38
    • Coyle, J.T.1    Tsai, G.2
  • 49
    • 0032441894 scopus 로고    scopus 로고
    • Modulation of N-methyl-d-aspartate receptor function by glycine transport
    • R. Bergeron, T.M. Meyer, J.T. Coyle, and R.W. Greene Modulation of N-methyl-d-aspartate receptor function by glycine transport Proc Natl Acad Sci USA 95 1998 15730 15734
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15730-15734
    • Bergeron, R.1    Meyer, T.M.2    Coyle, J.T.3    Greene, R.W.4
  • 51
    • 0037108758 scopus 로고    scopus 로고
    • Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia
    • I. Chumakov, M. Blumenfeld, O. Guerassimenko, L. Cavarec, M. Palicio, and H. Abderrahim Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia Proc Natl Acad Sci USA 99 2002 13675 13680
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13675-13680
    • Chumakov, I.1    Blumenfeld, M.2    Guerassimenko, O.3    Cavarec, L.4    Palicio, M.5    Abderrahim, H.6
  • 52
    • 2942521644 scopus 로고    scopus 로고
    • Association of G72/G30 with schizophrenia in the Chinese population
    • X. Wang, G. He, N. Gu, J. Yang, J. Tang, and Q. Chen Association of G72/G30 with schizophrenia in the Chinese population Biochem Biophys Res Commun. 319 2004 1281 1286
    • (2004) Biochem Biophys Res Commun. , vol.319 , pp. 1281-1286
    • Wang, X.1    He, G.2    Gu, N.3    Yang, J.4    Tang, J.5    Chen, Q.6
  • 53
    • 3442888075 scopus 로고    scopus 로고
    • The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations
    • D. Hall, J.A. Gogos, and M. Karayiorgou The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations Genes Brain Behav. 4 2004 240 248
    • (2004) Genes Brain Behav. , vol.4 , pp. 240-248
    • Hall, D.1    Gogos, J.A.2    Karayiorgou, M.3
  • 54
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of d-serine in patients with schizophrenia: Evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia
    • K. Hashimoto, T. Fukushima, E. Shimizu, N. Komatsu, H. Watanabe, and N. Shinoda Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia Arch Gen Psychiatr 60 2003 572 576
    • (2003) Arch Gen Psychiatr , vol.60 , pp. 572-576
    • Hashimoto, K.1    Fukushima, T.2    Shimizu, E.3    Komatsu, N.4    Watanabe, H.5    Shinoda, N.6
  • 55
    • 0030690403 scopus 로고    scopus 로고
    • The nagging question of the function of N-acetylaspartylglutamate
    • J.T. Coyle The nagging question of the function of N- acetylaspartylglutamate Neurobiol Dis. 4 1997 231 238
    • (1997) Neurobiol Dis. , vol.4 , pp. 231-238
    • Coyle, J.T.1
  • 56
    • 11144285440 scopus 로고    scopus 로고
    • NAAG reduces NMDA receptor current in CA1 hippocampel pyramidal neurons of acute slices and dissociated neurons
    • in press.
    • Bergeron R, Coyle JT, Tsai G, Greene RW. NAAG reduces NMDA receptor current in CA1 hippocampel pyramidal neurons of acute slices and dissociated neurons. Neuropsychopharmacology, in press.
    • Neuropsychopharmacology
    • Bergeron, R.1    Coyle, J.T.2    Tsai, G.3    Greene, R.W.4
  • 58
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Y. Hakak, J.R. Walker, C. Li, W.H. Wong, K.L. Davis, and J.D. Buxbaum Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia Proc Natl Acad Sci USA 98 2001 4746 4751
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4746-4751
    • Hakak, Y.1    Walker, J.R.2    Li, C.3    Wong, W.H.4    Davis, K.L.5    Buxbaum, J.D.6
  • 59
    • 0035309305 scopus 로고    scopus 로고
    • Identification of genes from a schizophrenia-linked translocation breakpoint region
    • C.A. Semple, R.S. Devon, S. Le Hellard, and D.J. Porteous Identification of genes from a schizophrenia-linked translocation breakpoint region Genomics 73 2001 123 126
    • (2001) Genomics , vol.73 , pp. 123-126
    • Semple, C.A.1    Devon, R.S.2    Le Hellard, S.3    Porteous, D.J.4
  • 61
    • 0035798252 scopus 로고    scopus 로고
    • Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
    • S. Erhardt, K. Blennow, C. Nordin, E. Skogh, L.H. Lindstrom, and G. Engberg Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia Neurosci Lett 313 2001 96 98
    • (2001) Neurosci Lett , vol.313 , pp. 96-98
    • Erhardt, S.1    Blennow, K.2    Nordin, C.3    Skogh, E.4    Lindstrom, L.H.5    Engberg, G.6
  • 62
    • 1842419381 scopus 로고    scopus 로고
    • Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia
    • C.L. Miller, I.C. Llenos, J.R. Dulay, M.M. Barillo, R.H. Yolken, and S. Weis Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia Neurobiol Dis. 15 2004 618 629
    • (2004) Neurobiol Dis. , vol.15 , pp. 618-629
    • Miller, C.L.1    Llenos, I.C.2    Dulay, J.R.3    Barillo, M.M.4    Yolken, R.H.5    Weis, S.6
  • 64
    • 18744366911 scopus 로고    scopus 로고
    • Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia
    • K. Toyooka, S. Iritani, T. Makifuchi, O. Shirakawa, N. Kitamura, and K. Maeda Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia J Neuroochem. 83 2002 797 806
    • (2002) J Neuroochem. , vol.83 , pp. 797-806
    • Toyooka, K.1    Iritani, S.2    Makifuchi, T.3    Shirakawa, O.4    Kitamura, N.5    Maeda, K.6
  • 65
    • 1242319331 scopus 로고    scopus 로고
    • Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia
    • E.S. Emamian, M. Karayiorgou, and J.A. Gogos Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia J Neurosci. 24 2004 1561 1564
    • (2004) J Neurosci. , vol.24 , pp. 1561-1564
    • Emamian, E.S.1    Karayiorgou, M.2    Gogos, J.A.3
  • 66
    • 2942590969 scopus 로고    scopus 로고
    • Human dysbindin (DTNBPl)gene expression in noimal brain and in schizophrenic prefrontal cortex and midbrain
    • C.S. Weickert, R.E. Straub, B.W. McClintock, M. Matsumoto, R. Hashimoto, and T.M. Hyde Human dysbindin (DTNBPl)gene expression in noimal brain and in schizophrenic prefrontal cortex and midbrain Arch Gen Psychiatr 61 2004 544 555
    • (2004) Arch Gen Psychiatr , vol.61 , pp. 544-555
    • Weickert, C.S.1    Straub, R.E.2    McClintock, B.W.3    Matsumoto, M.4    Hashimoto, R.5    Hyde, T.M.6
  • 67
    • 0141532459 scopus 로고    scopus 로고
    • Glutamate receptors and transporters in the hippocampus in schizophrenia
    • P.J. Harrison, A.J. Law, and S.L. Eastwood Glutamate receptors and transporters in the hippocampus in schizophrenia Ann NY Acad Sci. 1003 2003 94 101
    • (2003) Ann NY Acad Sci. , vol.1003 , pp. 94-101
    • Harrison, P.J.1    Law, A.J.2    Eastwood, S.L.3
  • 70
    • 0029116094 scopus 로고
    • Dose-finding trial of d-cyctoserine added to neuroleptics for negative symptoms in schizophrenia
    • D.C. Goff, G. Tsai, D.S. Manoach, and J.T. Coyle Dose-finding trial of d-cyctoserine added to neuroleptics for negative symptoms in schizophrenia Am J Psychiatr 152 1995 1213 1215
    • (1995) Am J Psychiatr , vol.152 , pp. 1213-1215
    • Goff, D.C.1    Tsai, G.2    Manoach, D.S.3    Coyle, J.T.4
  • 71
    • 0032902238 scopus 로고    scopus 로고
    • A placebo-controlled trial of d-cycloserine added to conventional neuroleptics in patients with schizophrenia
    • D.C. Goff, G. Tsaig, J. Levitt, E. Amico, D. Manoach, and D.A. Schoenfeld A placebo-controlled trial of d-cycloserine added to conventional neuroleptics in patients with schizophrenia Arch Gen Psychiatr 56 1999 21 27
    • (1999) Arch Gen Psychiatr , vol.56 , pp. 21-27
    • Goff, D.C.1    Tsaig, G.2    Levitt, J.3    Amico, E.4    Manoach, D.5    Schoenfeld, D.A.6
  • 72
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of d-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • U. Heresco-Levy, M. Ermilov, J. Shimoni, B. Shapira, G. Silipo, and D.C. Javitt Placebo-controlled trial of d-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia Am J Psychiatr 159 2002 480 482
    • (2002) Am J Psychiatr , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 73
    • 0029658545 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia
    • U. Heresco-Levy, D.C. Javitt, M. Ermilov, C. Mordel, A. Horowitz, and D. Kelly Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia Br J Psychiatr 169 1996 610 617
    • (1996) Br J Psychiatr , vol.169 , pp. 610-617
    • Heresco-Levy, U.1    Javitt, D.C.2    Ermilov, M.3    Mordel, C.4    Horowitz, A.5    Kelly, D.6
  • 76
    • 0032403626 scopus 로고    scopus 로고
    • D-Serine added to antipsychotics for the treatment of schizophrenia
    • G. Tsai, P. Yang, L.C. Chung, N. Lange, and J.T. Coyle d-Serine added to antipsychotics for the treatment of schizophrenia Biol Psychiatr 44 1998 1081 1089
    • (1998) Biol Psychiatr , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 77
    • 1542617755 scopus 로고    scopus 로고
    • Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia
    • G. Tsai, H.Y. Lane, P. Yang, M.Y. Chong, and N. Lange Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia Biol Psychiatr 5 2004 452 456
    • (2004) Biol Psychiatr , vol.5 , pp. 452-456
    • Tsai, G.1    Lane, H.Y.2    Yang, P.3    Chong, M.Y.4    Lange, N.5
  • 78
  • 80
    • 0032955821 scopus 로고    scopus 로고
    • Effect of clozapine and adjuynctive high-dose glycine in treatment-resistant schizophrenia
    • S.G. Potkin, Y. Jin, B.G. Bunney, J. Costa, and B. Gulasekaram Effect of clozapine and adjuynctive high-dose glycine in treatment-resistant schizophrenia Am J Psychiatr 156 1999 145 147
    • (1999) Am J Psychiatr , vol.156 , pp. 145-147
    • Potkin, S.G.1    Jin, Y.2    Bunney, B.G.3    Costa, J.4    Gulasekaram, B.5
  • 82
    • 0033557737 scopus 로고    scopus 로고
    • A placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia
    • D.C. Goff, D.C. Henderson, A.E. Evins, and E. Amico A placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia Biol Psychiatr 45 1999 512 514
    • (1999) Biol Psychiatr , vol.45 , pp. 512-514
    • Goff, D.C.1    Henderson, D.C.2    Evins, A.E.3    Amico, E.4
  • 83
    • 0347091934 scopus 로고    scopus 로고
    • Glutamatergic animal models of schizophrenia
    • B. Moghaddam, and M.E. Jackson Glutamatergic animal models of schizophrenia Ann NY Acad Sci. 1003 2003 131 137
    • (2003) Ann NY Acad Sci. , vol.1003 , pp. 131-137
    • Moghaddam, B.1    Jackson, M.E.2
  • 86
    • 0037092430 scopus 로고    scopus 로고
    • NMDA receptor antagonists disinhibit rat posterior cingulated and retrosplenial cortices: A potential mechanism of neurotoxicity
    • Q. Li, S. Clark, D.V. Lewis, and W.A. Wilson NMDA receptor antagonists disinhibit rat posterior cingulated and retrosplenial cortices: a potential mechanism of neurotoxicity J Neurosci. 22 2002 3070 3080
    • (2002) J Neurosci. , vol.22 , pp. 3070-3080
    • Li, Q.1    Clark, S.2    Lewis, D.V.3    Wilson, W.A.4


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