Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice

Journal of Virology

Volumn 82, Issue 7, 2008, Pages 3642-3653

  Korom, Maria ^a   Wylie, Kristine M ^a   Morrison, Lynda A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON RECEPTOR; INTERFERON; RIBONUCLEASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; GENETIC CODE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 2; KNOCKOUT MOUSE; MOUSE; NERVOUS SYSTEM; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; THERAPY RESISTANCE; VAGINA SMEAR; VIRION; VIRUS CELL INTERACTION; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; BRAIN; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 2, HUMAN; IMMUNOPRECIPITATION; INTERFERON TYPE I; INTERFERON-ALPHA; INTERFERON-BETA; MICE; MICE, KNOCKOUT; POINT MUTATION; PROTEIN BINDING; RIBONUCLEASES; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; VAGINA; VIRAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRION; VIRULENCE FACTORS; VIRUS ASSEMBLY;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; MUS; SIMPLEXVIRUS;

EID: 41149134311     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02409-07     Document Type: Article

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