The virion host shutoff protein of herpes simplex virus type 1: Messenger ribonucleolytic activity in vitro

Journal of Virology

Volumn 70, Issue 4, 1996, Pages 2411-2419

  Zelus, Bruce D ^a,c   Stewart, Richard S ^a   Ross, Jeff ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; MESSENGER RNA; MUTANT PROTEIN; RIBONUCLEASE; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RABBIT; RETICULOCYTE; RNA DEGRADATION; VERO CELL; VIRION;

EID: 0029919184     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.4.2411-2419.1996     Document Type: Article

References (53)

1. Bandyopadhyay, R., M. Coutts, A. Krowczynska, and G. Brawerman. 1990. Nuclease activity associated with mammalian mRNA in its native state: possible selectivity in mRNA decay Mol. Cell. Biol. 10:2060-2069
2. Becker, Y., E. Tavor, Y. Asher, C. Berkowitz, and M. Moyal. 1993. Effect of herpes simplex virus type 1 UL41 gene on the stability of mRNA from the cellular genes: β-actin, fibronectin, glucose transporter-1, and docking protein, and on virus intraperitoneal pathogenicity to newborn mice. Virus Genes 7:133-143.
3. Bernstein, P. L., D. J. Herrick, R. D. Prokipcak, and J. Ross. 1992 Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant. Genes Dev. 6:642-654.
4. Bernstein, P. L., and J. Ross. 1989 Poly(A), poly(A) binding protein and the regulation of mRNA stability. Trends Biochem. Sci. 14:373-377
5. Caruccio, N., and J. Ross. 1994. Purification of a human polyribosome-associated 3′ to 5′ exoribonuclease J Biol. Chem. 269:31814-31821.
6. Dompenciel, R. E., V. R. Garnepudi, and D. R. Schoenberg. 1995 Purification and characterization of an estrogen-regulated Xenopus liver polysomal nuclease involved in the selective destabilization of albumin mRNA. J. Biol. Chem. 270:6108-6118
7. Eichler, D. C., and N. Craig. 1994. Processing of eukaryotic ribosomal RNA Prog. Nucleic Acid Res. Mol. Biol 49:197-239.
8. Eichler, D. C., and S. J. Eales. 1982. Isolation and characterization of a single-stranded specific endoribonuclease from Ehrlich ascites tumor cells J. Biol. Chem. 257:14384-14389.
9. Eichler, D. C., and S. J. Eales. 1985. Purification and properties of a novel nucleolar exoribonuclease capable of degrading both single-stranded and double-stranded RNA. Biochemistry 24:686-691
10. Eichler, D. C., J. A. Liberatore, and M. Shumgard. 1993. Selection of a preribosomal processing site by a nucleolar endoribonuclease involves formation of a stable complex. Nucleic Acids Res. 21:5775-5781.
11. Elroy-Stein, O., J. R. Fuerst, and B. Moss. 1989 Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5′ sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system. Proc. Natl. Acad. Sci. USA 86:6126-6130.
12. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13
13. Fenwick, M. L., and J. Clark. 1983 The effect of cycloheximide on the accumulation and stability of functional α-mRNA in cells infected with herpes simplex virus. J. Gen. Virol 64:1955-1963.
14. Fenwick, M. L., and R. D. Everett. 1990. Inactivation of the shutoff gene (UL41) of herpes simplex viruses 1 and 2. J. Gen. Virol. 71:2961-2967.
15. Fenwick, M. L., S. Morse, and B. Roizman. 1979. Anatomy of herpes simplex virus DNA. XI. Apparent clustering of functions effecting rapid inhibition of host DNA and protein synthesis. J Virol 29:825-827.
16. Fenwick, M. L., and M. J. Walker. 1978 Suppression of the synthesis of cellular macromolecules by herpes simplex virus. J. Gen. Virol. 41:37-51.
17. Gorman, C., R. Padmanabhan, and B. H. Howard. 1983. High-efficiency DNA-mediated transformation of primate cells. Science 221:551-553.
18. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
19. Herrick, D. J., and J. Ross. 1994. The half-life of c-myc mRNA in growing and serum-stimulated cells influence of the coding and 3′ untranslated regions and role of ribosome translocation. Mol. Cell Biol. 14:2119-2128.
20. Higgins, S. J., and B. D. Hames (ed.), 1994. RNA processing: a practical approach. Oxford University Press, Oxford.
21. Hill, T., J. R. Sadler, and J. Betz. 1985. Virion component of herpes simplex virus type 1 KOS interferes with early shutoff of host protein synthesis induced by herpes simplex virus type 2 186. J. Virol. 56:312-316.
22. Jones, F. E., C. A. Smibert, and J. R. Smiley. 1995. Mutational analysis of the herpes simplex virus virion host shutoff protein, evidence that vhs functions in the absence of other viral proteins. J. Virol. 69:4863-4871.
23. Krieg, P. A., and D. Melton. 1984. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs. Nucleic Acids Res. 12: 7057-7070.
24. Krikorian, C. R., and G. S. Read. 1991. In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus J. Virol. 65: 112-122.
25. Kwong, A., and N. Frenkel. 1987. Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs. Proc. Natl. Acad. Sci. USA 84:1926-1930.
26. Lang, K., and R. Spritz. 1987. In vitro splicing pathways of pre-mRNAs containing multiple intervening sequences. Mol. Cell Biol. 7:3426-3437.
27. Masters, D. B., C. T. Griggs, and C. B. Berde. 1992. High sensitivity quantification of RNA from gels and autoradiograms with affordable optical scanning. BioTechniques 12:902-911.
28. McLauchlan, J., and F. J. Rixon. 1992. Characterization of enveloped tegument structures (L particles) produced by alphaherpesviruses: integrity of the tegument does not depend on the presence of capsid or envelope. J. Gen. Virol. 73:269-276.
29. Muhlrad, D., C. J. Decker, and R. Parker. 1994. Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′-3′ digestion of the transcript. Genes Dev. 8:855-866.
30. Nakai, H., I. H. Maxwell, and L. I. Pizer. 1982. Herpesvirus infection alters the steady-state levels of cellular polyadenylated RNA in polyoma virus-transformed BHK cells J. Virol. 42:1131-1134.
31. Oroskar, A. A., and G. S. Read. 1989. Control of mRNA stability by the virion host shutoff function of herpes simplex virus. J. Virol. 63:1897-1906.
32. Pak, A. S., D. N. Everly, K. Knight, and G. S. Read. 1995. The virion host shutoff protein of herpes simplex virus inhibits reporter gene expression in the absence of other viral gene products Virology 211:491-506.
33. Preston, C. M., M. C. Frame, and M. E. M. Campbell. 1988. A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence. Cell 52:425-434.
34. 33a.Read, G. S. Personal communication.
35. Read, G. S., and N. Frenkel. 1983. Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of α (immediate early) viral polypeptides. J. Virol. 46: 498-512.
36. Read, G. S., B. M. Karr, and K. Knight. 1993 Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide. J. Virol. 67: 7149-7160.
37. Ross, J. 1995. mRNA stability in mammalian cells. Microbiol. Rev. 59: 423-450.
38. Ross, J., and G. Kobs. 1986. Histone H4 messenger RNA decay in cell-free extracts initiates at or near the 3′ terminus and proceeds 3′ to 5′. J. Mol. Biol. 188:579-593.
39. Ross, J., G. Kobs, G. Brewer, and S. W. Peltz. 1987. Properties of the exonuclease activity that degrades H4 histone mRNA. J. Biol. Chem. 262: 9374-9381.
40. Sandri-Goldin, R. M., and G. E. Mendoza. 1992 A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing. Genes Dev. 6:848-563.
41. Schek, N., and S. Bachenheimer. 1985. Degradation of cellular mRNAs induced by a virion-associated factor during herpes simplex virus infection of Vero cells. J. Virol. 55:601-610.
42. Shumgard, C. M., and D. C. Eichler. 1988. Ribosomal RNA processing: limited cleavages of mouse preribosomal RNA by a nucleolar endoribonuclease include the early +650 processing site. J Biol. Chem. 263:19346-19352.
43. Shumgard, C. M., C. Torres, and D. C. Eichler. 1990. In vitro processing at the 3′-terminal region of pre-18S rRNA by a nucleolar endoribonuclease. Mol. Cell. Biol. 10:3868-3872.
44. Silverstein, S., and D. L. Engelhardt. 1979. Alterations in the protein synthetic apparatus of cells infected with herpes simplex virus. Virology 95: 334-342.
45. Smibert, C. A., D. C. Johnson, and J. R. Smiley. 1992. Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41. J. Gen. Virol. 73:467-470.
46. Smibert, C. A., B. Papova, P. Xiao, J. Capone, and J. R. Smiley. 1994. Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs. J. Virol. 68:2339-2346.
47. Smith, I. L., M. A. Hardwicke, and R. Sandri-Goldin. 1992. Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression. Virology 186:74-86.
48. Sorenson, C. M., P. A. Hart, and J. Ross. 1991. Analysis of herpes simplex virus-induced mRNA destabilizing activity using an in vitro mRNA decay system. Nucleic Acids Res. 19:4459-4465.
49. Stevens, A., and M. K. Maupin. 1987. A 5′ to 3′ exoribonuclease of Saccharomyces cerevisiae: size and novel substrate specificity. Arch. Biochem. Biophys. 252:339-347
50. Strom, T., and N. Frenkel. 1987. Effects of herpes simplex virus on mRNA stability. J. Virol. 61:2198-2207
51. Visalli, R. J., and C. R. Brandt. 1993. The HSV-1 UL45 18 kDa gene product is a true late protein and a component of the virion. Virus Res. 24:167-178.
52. Wagner, E. K. (ed.). 1991. Herpesvirus transcription and its regulation. CRC Press, Boca Raton, Fla.
53. Zhou, A., B. A. Hassel, and R. H. Silverman. 1993. Expression cloning of 2′-5′ A-dependent RNAase: a uniquely regulated mediator of interferon action. Cell 72:753-765.