Herpes simplex virus type 2-mediated disease is reduced in mice lacking RNase L

Virology

Volumn 360, Issue 2, 2007, Pages 322-328

  Duerst, Rebecca J ^a   Morrison, Lynda A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Genital; Herpes simplex virus; IFN ; Inflammation; RNase L; Type I interferon

Indexed keywords

RIBONUCLEASE L;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; DISEASE SEVERITY; FEMALE; FEMALE GENITAL SYSTEM; HERPES; HERPES SIMPLEX VIRUS 2; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTIC INFILTRATION; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; VAGINA EPITHELIUM; VIRUS INFECTION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; BODY WEIGHT; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ENDORIBONUCLEASES; FEMALE; GENITALIA, FEMALE; HERPES SIMPLEX; HERPESVIRUS 2, HUMAN; IMMUNITY, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; VIRULENCE;

HUMAN HERPESVIRUS 2; MUS; SIMPLEXVIRUS;

EID: 33947598286     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.10.042     Document Type: Article

References (47)

1. Al-khatib K., Williams B.R., Silverman R.H., Halford W., and Carr D.J. The murine double-stranded RNA-dependent protein kinase PKR and the murine 2′,5′-oligoadenylate synthetase-dependent RNase L are required for IFNβ-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture. Virology 313 (2003) 126-135
2. Al-khatib K., Williams B.R., Silverman R.H., Halford W., and Carr D.J. Distinctive roles for 2′,5′-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta. J. Immunol. 172 (2004) 5638-5647
3. Al-khatib K., Williams B.R., Silverman R.H., Halford W., and Carr D.J. Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection. Exp. Eye Res. 80 (2005) 167-173
4. Austin B.A., James C., Silverman R.H., and Carr D.J.J. Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-β during acute ocular herpes simplex virus type 1 infection. J. Immunol. 175 (2005) 1101-1106
5. Carr D.J., Al-Khatib K., James C.M., and Silverman R. Interferon-β suppresses herpes simplex virus type 1 replication in trigeminal ganglion cells through an RNase L-dependent pathway. J. Neuroimmunol. 141 (2003) 40-46
6. Cassady K.A., Gross M., and Roizman B. The herpes simplex virus US11 protein effectively compensates for the gamma 1 (34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2. J. Virol. 72 (1998) 8620-8626
7. Cassady K.A., Gross M., and Roizman B. The second-site mutation in the herpes simplex virus recombinants lacking the gamma 134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylatin of eIF-2alpha. J. Virol. 72 (1998) 7005-7011
8. Castelli J.C., Hassel B.A., Maran A., Paranjape J., Hewitt J.A., Li X.L., Hsu Y.T., Silverman R.H., and Youle R.J. The role of 2′-5′ oligoadenylate-activated ribonuclease L in apoptosis. Cell Death Differ. 5 (1998) 313-320
9. Cayley P.I., Davies J.A., McCullagh K.G., and Kerr I.M. Activation of the ppp(A2′p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2′p)nA-dependent RNase. Eur. J. Biochem. 143 (1984) 165-174
10. Floyd-Smith G. (2′-5′)An-dependent endoribonuclease: enzyme levels are regulated by IFN beta, IFN gamma, and cell culture conditions. J. Cell. Biochem. 38 (1988) 13-21
11. + T cell line specific for an immunodominant VP2 epitope. J. Immunol. 152 (1994) 919-929
12. Glass W.G., Lim J.K., Cholera R., Pletnev A.G., Gao J.L., and Murphy P.M. Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection. J. Exp. Med. 202 (2005) 1087-1098
13. Harandi A.M., Svennerholm B., Holmgren J., and Eriksson K. Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice. J. Gen. Virol. 82 (2001) 845-853
14. Harle P., Noisakran S., and Carr D.J. The application of a plasmid DNA encoding IFN-alpha 1 postinfection enhances cumulative survival of herpes simplex virus type 2 vaginally infected mice. J. Immunol. 166 (2001) 1803-1812
15. Harle P., Cull V., Guo L., Papin J., Lawson C., and Carr D.J. Transient transfection of mouse fibroblasts with type I interferon transgenes provides various degrees of protection against herpes simplex virus infection. Antiviral Res. 56 (2002) 39-49
16. Harle P., Cull V.F., Agbaga M.P., Silverman R.F., Williams B.R., James C., and Carr D.J. Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication. J. Virol. 76 (2002) 6558-6567
17. He B., Gross M., and Roizman B. The gamma (1) 34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1 alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 843-848
18. Hendricks R.L., Weber P.C., Taylor J.L., Koumbis A., Tumpey T.M., and Glorioso J.C. Endogenously produced interferon alpha protects mice from herpes simplex virus type 1 corneal disease. J. Gen. Virol. 72 (1991) 1601-1610
19. Keadle T.L., Morris J.L., Pepose J.S., and Stuart P.M. CD4(+) and CD8(+) cells are key participants in the development of recurrent herpetic stromal keratitis in mice. Microb. Pathog. 32 (2002) 255-262
20. Khabar K.S.A., Dhalla M., Siddiqui Y., Zhou A., Ahdal M.N., Der S.D., Silverman R.H., and Williams B.R.G. Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes. J. Interferon Cytokine Res. 20 (2000) 653-659
21. Klotzbucher A., Mittnacht S., Kirchner H., and Jacobsen H. Different effects of IFN gamma and IFN alpha/beta on "immediate early" gene expression of HSV-1. Virology 179 (1990) 487-491
22. Knipe D.M., and Spang A.E. Definition of a series of stages in the association of two herpes viral proteins with the cell nucleus. J. Virol. 43 (1982) 314-324
23. Lane T.E., Liu M.T., Chen B.P., Asensio V.C., Samawi R.M., Paoletti A.D., Campbell I.L., Kunkel S.L., Fox H.S., and Buchmeier M.J. A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination. J. Virol. 74 (2000) 1415-1424
24. Lausch R.N., Su Y.H., Ritchie M., and Oakes J.E. Evidence endogenous interferon production contributed to the lack of ocular virulence of an HSV intertypic recombinant. Curr. Eye Res. 10 (1991) 39-45
25. Leib D.A., Harrison T.E., Laslo K.M., Machalek M.A., Moorman N.J., and Virgin H.W. Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo. J. Exp. Med. 189 (1999) 663-672
26. Leib D.A., Machalek M.A., Williams B.R., Silverman R.H., and Virgin H.W. Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 6097-6101
27. Leitner W.W., Hwang L.N., Deveer M.J., Zhou A., Silverman R.H., Williams B.R.G., Dubensky T.W., Ying H., and Restifo N.P. Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Nat. Med. 9 (2003) 33-39
28. Marten N.W., Stohlman S.A., and Bergmann C.C. MHV infection of the CNS: mechanisms of immune-mediated control. Viral Immunol. 14 (2001) 1-18
29. Milligan G.N., and Bernstein D.I. Analysis of herpes simplex virus-specific T cells in the murine female genital tract following genital infection with herpes simplex virus type 2. Virology 212 (1995) 481-489
30. Milligan G.N., Dudley-McClain K.L., Young C.G., and Chu C.F. T-cell-mediated mechanisms involved in resolution of genital herpes simplex virus type 2 (HSV-2) infection of mice. J. Reprod. Immunol. 61 (2004) 115-127
31. Mittnacht S., Straub P., Kirchner H., and Jacobsen H. Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription. Virology 164 (1988) 201-210
32. Morrison L.A., and Knipe D.M. Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1. Virology 320 (1996) 402-413
33. Morrison L.A., Da Costa X.J., and Knipe D.M. Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge. Virology 243 (1998) 178-187
34. Murphy J.A., Duerst R.J., Smith T.J., and Morrison L.A. Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo. J. Virol. 77 (2003) 9337-9345
35. 1 cells in ocular tissues during herpetic stromal keratitis. J. Immunol. 149 (1992) 3035-3039
36. Noisakran S., Campbell I.L., and Carr D.J. Ectopic expression of DNA encoding IFN-alpha 1 in the cornea protects mice from herpes simplex virus type 1-induced encephalitis. J. Immunol. 162 (1999) 4184-4190
37. Noisakran S., Campbell I.L., and Carr D.J. IFN-alpha1 plasmid construct affords protection against HSV-1 infection in transfected L929 fibroblasts. J. Interferon Cytokine Res. 20 (2000) 107-115
38. Oberman F., and Panet A. Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells. J. Gen. Virol. 69 (1988) 1167-1177
39. Oberman F., and Panet A. Characterization of the early steps of herpes simplex virus replication in interferon-treated human cells. J. Interferon Res. 9 (1989) 563-571
40. + T-cells in exacerbation of corneal scarring in mice. Curr. Eye Res. 29 (2004) 145-151
41. Palliser D., Chowdhury D., Wang Q.Y., Lee S.J., Bronson R.T., Knipe D.M., and Lieberman J. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infections. Nature 439 (2006) 89-94
42. + T cells. J. Immunol. 162 (1999) 1624-1632
43. Silverman R.H., Zhou A., Auerbach M.B., Kish D., Gorbachev A., and Fairchild R.L. Skin allograft rejection is suppressed in mice lacking the antiviral enzyme, 2′,5′-oligoadenylate-dependent RNase L. Viral Immunol. 15 (2002) 77-88
44. Smith T.J., Silverman R.H., and Leib D.A. RNase L activity does not contribute to host RNA degradation induced by herpes simplex virus infection. J. Gen. Virol. 84 (2003) 925-928
45. Zheng X., Silverman R.H., Zhou A., Goto T., Kwon B.S., Kaufman H.E., and Hill J.M. Increased severity of HSV-1 keratitis and mortality in mice lacking the 2-5A-dependent RNase L gene. Invest. Ophthalmol. Visual Sci. 42 (2002) 120-126
46. Zhou A., Paranjape J., Brown T.L., Nie H., Naik S., Dong B., Chang A., Trapp B., Fairchild R., Colmenares C., and Silverman R.H. Interferon action and apoptosis are defective in mice devoid of 2′,5′-oligoadenylate-dependent RNase L. EMBO J. 16 (1997) 6355-6363
47. Zhou A., Paranjape J.M., Brown T.L., Hassel B.A., Nie H., Shah S., Galinski B., and Siverman R.H. Impact of RNase L overexpression on viral and cellular growth and death. J. Interferon Cytokine Res. 18 (1998) 953-961