A new strategy for the synthesis of 1,4-benzodiazepine derivatives based on the tandem N-alkylation-ring opening-cyclization reactions of methyl 1-arylaziridine-2-carboxylates with N-[2-bromomethyl(phenyl)]trifluoroacetamides

Journal of Organic Chemistry

Volumn 73, Issue 5, 2008, Pages 1979-1982

  Wang, Jin Yuan ^a   Guo, Xue Fei ^a   Wang, De Xiang ^a   Huang, Zhi Tang ^a   Wang, Mei Xiang ^a  

^a INSTITUTE OF CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; DERIVATIVES; NUCLEOPHILES; REGIOSELECTIVITY; SYNTHESIS (CHEMICAL);

CHEMICAL MANIPULATIONS; MEDICINAL CHEMISTRY;

AROMATIC COMPOUNDS;

BENZODIAZEPINE DERIVATIVE;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; HYDROLYSIS; ONE POT SYNTHESIS; RING OPENING;

ACETAMIDES; ALKYLATION; BENZODIAZEPINES; CARBOXYLIC ACIDS; CYCLIZATION;

EID: 41149097770     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo7024306     Document Type: Article

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