메뉴 건너뛰기




Volumn 10, Issue 1, 2008, Pages 33-43

NMDA receptors and colitis: Basic science and clinical implications

Author keywords

Colitis; NMDA receptor; Visceral hypersensitivity; Visceral pain

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; CALCITONIN GENE RELATED PEPTIDE; CYTOKINE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; NEUROTRANSMITTER; TURPENTINE; ZYMOSAN;

EID: 40949165050     PISSN: 1542961X     EISSN: 15553876     Source Type: Journal    
DOI: 10.3727/154296108783994013     Document Type: Review
Times cited : (19)

References (121)
  • 1
    • 0028951318 scopus 로고
    • Selective dysfunction of mechanosensitive intestinal afferents in irritable bowel syndrome
    • Accarino, A. M.; Azpiroz, F.; Malagelada, J. R. Selective dysfunction of mechanosensitive intestinal afferents in irritable bowel syndrome. Gastroenterology 108:636-643; 1995.
    • (1995) Gastroenterology , vol.108 , pp. 636-643
    • Accarino, A.M.1    Azpiroz, F.2    Malagelada, J.R.3
  • 2
    • 0034321927 scopus 로고    scopus 로고
    • A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development
    • Al-Chaer, E. D.; Kawasaki, M.; Pasticha, P. J. A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development. Gastroenterology 119:1276-1285; 2000.
    • (2000) Gastroenterology , vol.119 , pp. 1276-1285
    • Al-Chaer, E.D.1    Kawasaki, M.2    Pasticha, P.J.3
  • 3
    • 0029998095 scopus 로고    scopus 로고
    • Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway
    • Al-Chaer, E. D.; Lawand, N. B.; Westlund, K. N.; Willis, W. D. Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway. J. Neurophysiol. 76(4):2675-2690; 1996.
    • (1996) J. Neurophysiol , vol.76 , Issue.4 , pp. 2675-2690
    • Al-Chaer, E.D.1    Lawand, N.B.2    Westlund, K.N.3    Willis, W.D.4
  • 4
    • 0031913847 scopus 로고    scopus 로고
    • Sensitization of pain pathways in the spinal cord: Cellular mechanisms
    • Baranauskas, G.; Nistri, A. Sensitization of pain pathways in the spinal cord: Cellular mechanisms. Prog. Neurobiol. 54:349-365; 1998.
    • (1998) Prog. Neurobiol , vol.54 , pp. 349-365
    • Baranauskas, G.1    Nistri, A.2
  • 5
    • 0042236629 scopus 로고    scopus 로고
    • Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: Species and strain differences
    • Bon, K.; Lichtensteiger, C. A.; Wilson, S. G.; Mogil, J. S. Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: Species and strain differences. J. Urol. 170:1008-1012; 2003.
    • (2003) J. Urol , vol.170 , pp. 1008-1012
    • Bon, K.1    Lichtensteiger, C.A.2    Wilson, S.G.3    Mogil, J.S.4
  • 6
    • 3242793203 scopus 로고    scopus 로고
    • Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons
    • Brenner, G. J.; Ji, R. R.; Shaffer, S.; Woolf, C. J. Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons. Eur. J. Neurosci. 20:375-384; 2004.
    • (2004) Eur. J. Neurosci , vol.20 , pp. 375-384
    • Brenner, G.J.1    Ji, R.R.2    Shaffer, S.3    Woolf, C.J.4
  • 7
    • 0028814455 scopus 로고
    • Effects of intracolonic acetic acid on responses to colorectal distension in the rat
    • Bunton, M. B.; Gebhart, G. F. Effects of intracolonic acetic acid on responses to colorectal distension in the rat. Brain Res. 672:77-82; 1995.
    • (1995) Brain Res , vol.672 , pp. 77-82
    • Bunton, M.B.1    Gebhart, G.F.2
  • 8
    • 0029889117 scopus 로고    scopus 로고
    • Transiently catecholaminergic cells in the fetal rat express mRNA for the glutamate NMDAR1 receptor
    • Burns, G. A.; Ulibarri, C.; Stephens, K. E. Transiently catecholaminergic cells in the fetal rat express mRNA for the glutamate NMDAR1 receptor. Brain Res. 718:117-123; 1996.
    • (1996) Brain Res , vol.718 , pp. 117-123
    • Burns, G.A.1    Ulibarri, C.2    Stephens, K.E.3
  • 9
    • 0036828497 scopus 로고    scopus 로고
    • NMDA-receptor trafficking and targeting: Implications for synaptic transmission and plasticity
    • Carroll, R. C.; Zukin, R. S. NMDA-receptor trafficking and targeting: Implications for synaptic transmission and plasticity. Trends Neurosci. 25:571-577; 2002.
    • (2002) Trends Neurosci , vol.25 , pp. 571-577
    • Carroll, R.C.1    Zukin, R.S.2
  • 10
    • 30844462124 scopus 로고    scopus 로고
    • Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation
    • Caudle, R. M.; Perez, F. M.; Valle-Pinero, A. Y.; Iadarola, M. J. Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation. Mol. Pain 1:25; 2005.
    • (2005) Mol. Pain , vol.1 , pp. 25
    • Caudle, R.M.1    Perez, F.M.2    Valle-Pinero, A.Y.3    Iadarola, M.J.4
  • 11
    • 0022428746 scopus 로고
    • Visceral nociception: Peripheral and central aspects of visceral nociceptive systems
    • Cervero, F. Visceral nociception: Peripheral and central aspects of visceral nociceptive systems. Phil. Trans. R Soc. Lond. B Biol. Sci. 308:325-337; 1985.
    • (1985) Phil. Trans. R Soc. Lond. B Biol. Sci , vol.308 , pp. 325-337
    • Cervero, F.1
  • 12
    • 4644346283 scopus 로고    scopus 로고
    • Understanding the signaling and transmission of visceral nociceptive events
    • Cervero, F.; Laird, J. M. Understanding the signaling and transmission of visceral nociceptive events. J. Neurobiol. 61:45-54; 2004.
    • (2004) J. Neurobiol , vol.61 , pp. 45-54
    • Cervero, F.1    Laird, J.M.2
  • 13
    • 0033583981 scopus 로고    scopus 로고
    • Visceral pain
    • Cervero, F.; Laird, J. M. Visceral pain. Lancet 353:2145-2148; 1999.
    • (1999) Lancet , vol.353 , pp. 2145-2148
    • Cervero, F.1    Laird, J.M.2
  • 15
    • 0033972660 scopus 로고    scopus 로고
    • Differences in somatic perception in female patients with irritable bowel syndrome with and without fibromyalgia
    • Chang, L.; Mayer, E. A.; Johnson, T.; FitzGerald, L. Z.; Naliboff, B. Differences in somatic perception in female patients with irritable bowel syndrome with and without fibromyalgia. Pain 84:297-307; 2000.
    • (2000) Pain , vol.84 , pp. 297-307
    • Chang, L.1    Mayer, E.A.2    Johnson, T.3    FitzGerald, L.Z.4    Naliboff, B.5
  • 16
    • 0002946460 scopus 로고    scopus 로고
    • Intracolonid zymosan produces visceral hyeralgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors
    • Coutinho, S. V.; Meiler, S. T.; Gebhart, G. F. Intracolonid zymosan produces visceral hyeralgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors. Brain Res. 736(1-2):7-15; 1996.
    • (1996) Brain Res , vol.736 , Issue.1-2 , pp. 7-15
    • Coutinho, S.V.1    Meiler, S.T.2    Gebhart, G.F.3
  • 17
    • 0034589730 scopus 로고    scopus 로고
    • Role of sensitized pelvic nerve afferents from the inflamed rat colon in the maintenance of visceral hyperalgesia
    • Coutinho, S. V.; Su, X.; Sengupta, J. N.; Gebhart, G. F. Role of sensitized pelvic nerve afferents from the inflamed rat colon in the maintenance of visceral hyperalgesia. Prog. Brain Res. 129:375-387; 2000.
    • (2000) Prog. Brain Res , vol.129 , pp. 375-387
    • Coutinho, S.V.1    Su, X.2    Sengupta, J.N.3    Gebhart, G.F.4
  • 18
    • 0035840816 scopus 로고    scopus 로고
    • The role of NMDA receptor and nitric oxide in visceral hyperalgesia
    • Coutinho, S. V.; Urban, M. O.; Gebhart, G. F. The role of NMDA receptor and nitric oxide in visceral hyperalgesia. Eur. J. Pharmacol. 429:319-325; 2001.
    • (2001) Eur. J. Pharmacol , vol.429 , pp. 319-325
    • Coutinho, S.V.1    Urban, M.O.2    Gebhart, G.F.3
  • 19
    • 0028215991 scopus 로고
    • Pathophysiology of pain
    • Cross, S. A. Pathophysiology of pain. Mayo Clin. Proc. 69:375-383; 1994.
    • (1994) Mayo Clin. Proc , vol.69 , pp. 375-383
    • Cross, S.A.1
  • 20
  • 21
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity development and disease
    • Cull-Candy, S.; Brickley, A.; Farrant, M. NMDA receptor subunits: Diversity development and disease. Curr. Opin. Neurobiol. 11:327-335; 2001.
    • (2001) Curr. Opin. Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, A.2    Farrant, M.3
  • 23
    • 0019866699 scopus 로고
    • Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine
    • de Groat, W. C.; Nadelhaft, I.; Milne, R. J.; Booth, A. M.; Morgan, C.; Thor, K. Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine. J. Auton. Nerv. Syst. 3:135-160; 1981.
    • (1981) J. Auton. Nerv. Syst , vol.3 , pp. 135-160
    • de Groat, W.C.1    Nadelhaft, I.2    Milne, R.J.3    Booth, A.M.4    Morgan, C.5    Thor, K.6
  • 24
    • 0001663637 scopus 로고
    • Neurophysiology of micturition and its modification in animal models of human disease
    • Maggi, C. A, ed, London: Harwood;
    • de Groat, W. C.; Booth, A. M.; Yoshimura, N. Neurophysiology of micturition and its modification in animal models of human disease. In: Maggi, C. A., ed. The autonomic nervous system. London: Harwood; 1993:227-290.
    • (1993) The autonomic nervous system , pp. 227-290
    • de Groat, W.C.1    Booth, A.M.2    Yoshimura, N.3
  • 26
    • 0036288594 scopus 로고    scopus 로고
    • Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome
    • Delvaux, M. Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome. Gut 51(Suppl. 1):i67-i71; 2002.
    • (2002) Gut , vol.51 , Issue.SUPPL. 1
    • Delvaux, M.1
  • 28
    • 0026500432 scopus 로고
    • Activity-dependent neuronal plasticity following tissue injury and inflammation
    • Dubner, R.; Ruda, M. A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15:96-103; 1992.
    • (1992) Trends Neurosci , vol.15 , pp. 96-103
    • Dubner, R.1    Ruda, M.A.2
  • 29
    • 0026686821 scopus 로고
    • Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C
    • Durand, G. M.; Gregor, P.; Zheng, X.; Bennett, M. V.; Uhl, G. R.; Zukin, R. S. Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C. Proc. Natl. Acad. Sci. USA 89:9359-9363; 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9359-9363
    • Durand, G.M.1    Gregor, P.2    Zheng, X.3    Bennett, M.V.4    Uhl, G.R.5    Zukin, R.S.6
  • 30
    • 0027323130 scopus 로고
    • Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C
    • Durand, G. M.; Bennett, M. V.; Zukin, R. S. Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C. Proc. Natl. Acad. Sci. USA 90:6731-6735; 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6731-6735
    • Durand, G.M.1    Bennett, M.V.2    Zukin, R.S.3
  • 31
    • 0035089509 scopus 로고    scopus 로고
    • Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder
    • Farquhar-Smith, W. P.; Rice, A. S. Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. Anesthesiology 94:507-513; 2001.
    • (2001) Anesthesiology , vol.94 , pp. 507-513
    • Farquhar-Smith, W.P.1    Rice, A.S.2
  • 32
    • 0033666317 scopus 로고    scopus 로고
    • Assembly of new individual excitatory synapses: Time course and temporal order of synaptic molecule recruitment
    • Friedman, H. V.; Bresler, T.; Garner, C. C.; Ziv, N. E. Assembly of new individual excitatory synapses: Time course and temporal order of synaptic molecule recruitment. Neuron 27:57-69; 2000.
    • (2000) Neuron , vol.27 , pp. 57-69
    • Friedman, H.V.1    Bresler, T.2    Garner, C.C.3    Ziv, N.E.4
  • 35
    • 0033067881 scopus 로고    scopus 로고
    • Recent and forgotten aspects of visceral pain
    • Giamberardino, M. A. Recent and forgotten aspects of visceral pain. Eur. J. Pain 3:77-92; 1999.
    • (1999) Eur. J. Pain , vol.3 , pp. 77-92
    • Giamberardino, M.A.1
  • 36
    • 0029032399 scopus 로고
    • Artificial ureteral calculosis in rats: Behavioural characterization of visceral pain episodes and their relationship with referred lumbar muscle hyperalgesia
    • Giamberardino, M. A.; Valente, R.; de Bigontina, P.; Vecchiet, L. Artificial ureteral calculosis in rats: Behavioural characterization of visceral pain episodes and their relationship with referred lumbar muscle hyperalgesia. Pain 61:459-469; 1995.
    • (1995) Pain , vol.61 , pp. 459-469
    • Giamberardino, M.A.1    Valente, R.2    de Bigontina, P.3    Vecchiet, L.4
  • 37
    • 0031017067 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptors expressed in a nonneuronal cell line mediate subunit-specific increases in free intracellular calcium
    • Grant, E. R.; Bacskai, B. J.; Pleasure, D. E.; Pritchett, D. B.; Gallagher, M. J.; Kendrick, S. J.; Kricka, L. J.; Lynch, D. R. N-methyl-D-aspartate receptors expressed in a nonneuronal cell line mediate subunit-specific increases in free intracellular calcium. J. Biol. Chem. 272:647-656; 1997.
    • (1997) J. Biol. Chem , vol.272 , pp. 647-656
    • Grant, E.R.1    Bacskai, B.J.2    Pleasure, D.E.3    Pritchett, D.B.4    Gallagher, M.J.5    Kendrick, S.J.6    Kricka, L.J.7    Lynch, D.R.8
  • 39
    • 0027392895 scopus 로고
    • Receptive properties of myelinated primary afferents innervating the inflamed urinary bladder of the cat
    • Habler, H-J.; Janig, W.; Koltzenburg, M. Receptive properties of myelinated primary afferents innervating the inflamed urinary bladder of the cat. J. Neurophysiol. 69:395-405; 1993.
    • (1993) J. Neurophysiol , vol.69 , pp. 395-405
    • Habler, H.-J.1    Janig, W.2    Koltzenburg, M.3
  • 40
    • 0032943556 scopus 로고    scopus 로고
    • Modification of glutamate receptor channels: Molecular mechanisms and functional consequences
    • Hatt, H. Modification of glutamate receptor channels: Molecular mechanisms and functional consequences. Naturwissenschaften 86:177-186; 1999.
    • (1999) Naturwissenschaften , vol.86 , pp. 177-186
    • Hatt, H.1
  • 41
    • 0027197230 scopus 로고
    • Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
    • Hollmann, M.; Boulter, J.; Maron, C.; Beasley, L.; Sullivan, J.; Pecht, G.; Heinemann, S. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron 10:943-954; 1993.
    • (1993) Neuron , vol.10 , pp. 943-954
    • Hollmann, M.1    Boulter, J.2    Maron, C.3    Beasley, L.4    Sullivan, J.5    Pecht, G.6    Heinemann, S.7
  • 43
    • 0026664870 scopus 로고
    • Role of calcitonin gene-related peptide in gastrointestinal blood flow
    • Holzer, P.; Lippe, I. T. Role of calcitonin gene-related peptide in gastrointestinal blood flow. Ann. NY Acad. Sc. 657:228-239; 1992.
    • (1992) Ann. NY Acad. Sc , vol.657 , pp. 228-239
    • Holzer, P.1    Lippe, I.T.2
  • 44
    • 0030894118 scopus 로고    scopus 로고
    • The effects of an intrathecal NMDA antagonist (AP5) on the behavioral changes induced by colorectal inflammation with turpentine in rats
    • Ide, Y.; Maehara, Y.; Tsukahara, S.; Kitahata, L. M.; Collins, J. G. The effects of an intrathecal NMDA antagonist (AP5) on the behavioral changes induced by colorectal inflammation with turpentine in rats. Life Sci. 60(16):1359-1363; 1997.
    • (1997) Life Sci , vol.60 , Issue.16 , pp. 1359-1363
    • Ide, Y.1    Maehara, Y.2    Tsukahara, S.3    Kitahata, L.M.4    Collins, J.G.5
  • 45
    • 0032876972 scopus 로고    scopus 로고
    • Inflammation of the rat urinary bladder is associated with a referred thermal hyperalgesia which is nerve growth factor dependent
    • Jaggar, S. I.; Scott, H. C.; Rice, A. S. Inflammation of the rat urinary bladder is associated with a referred thermal hyperalgesia which is nerve growth factor dependent. Br. J. Anaesth. 83:442-448; 1999.
    • (1999) Br. J. Anaesth , vol.83 , pp. 442-448
    • Jaggar, S.I.1    Scott, H.C.2    Rice, A.S.3
  • 46
    • 0031776783 scopus 로고    scopus 로고
    • The anti- hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    • Jaggar, S. I.; Hasnie, F. S.; Sellaturay, S.; Rice, A. S. The anti- hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain 76:189-199; 1998.
    • (1998) Pain , vol.76 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.4
  • 47
    • 0035125971 scopus 로고    scopus 로고
    • The capsaicin analogue SDZ249-665 attenuates the hyperreflexia and referred hyperalgesia associated with inflammation of the rat urinary bladder
    • Jaggar, S. I.; Scott, H. C.; James, I. F.; Rice, A. S. The capsaicin analogue SDZ249-665 attenuates the hyperreflexia and referred hyperalgesia associated with inflammation of the rat urinary bladder. Pain 89:229-235; 2001.
    • (2001) Pain , vol.89 , pp. 229-235
    • Jaggar, S.I.1    Scott, H.C.2    James, I.F.3    Rice, A.S.4
  • 48
    • 0024994606 scopus 로고
    • On the function of spinal primary afferent fibres supplying colon and urinary bladder
    • Janig, W.; Koltzenburg, M. On the function of spinal primary afferent fibres supplying colon and urinary bladder. J. Auton. Nerv. Syst. 30(Suppl.):S89-S96; 1990.
    • (1990) J. Auton. Nerv. Syst , vol.30 , Issue.SUPPL.
    • Janig, W.1    Koltzenburg, M.2
  • 49
    • 0033082978 scopus 로고    scopus 로고
    • The effects of excitatory amino acids on isolated gut segments of the rat
    • Jankovic, S. M.; Milovanovic, D.; Matovic, M.; Iric-Cupic, V. The effects of excitatory amino acids on isolated gut segments of the rat. Pharmacol. Res. 39:143-148; 1999.
    • (1999) Pharmacol. Res , vol.39 , pp. 143-148
    • Jankovic, S.M.1    Milovanovic, D.2    Matovic, M.3    Iric-Cupic, V.4
  • 50
    • 0034786920 scopus 로고    scopus 로고
    • Spinal NMDA receptors contribute to neuronal processing of acute noxious and nonnoxious colorectal stimulation in the rat
    • Ji, Y.; Traub, R. J. Spinal NMDA receptors contribute to neuronal processing of acute noxious and nonnoxious colorectal stimulation in the rat. J. Neurophysiol. 86(4):1783-1791; 2001.
    • (2001) J. Neurophysiol , vol.86 , Issue.4 , pp. 1783-1791
    • Ji, Y.1    Traub, R.J.2
  • 51
    • 3242677092 scopus 로고    scopus 로고
    • Colorectal distension-induced suppression of a nociceptive somatic reflex response in the rat: Modulation by tissue injury or inflammation
    • Kalmari, J.; Pertovaara, A. Colorectal distension-induced suppression of a nociceptive somatic reflex response in the rat: Modulation by tissue injury or inflammation. Brain Res. 1018:106-110; 2004.
    • (2004) Brain Res , vol.1018 , pp. 106-110
    • Kalmari, J.1    Pertovaara, A.2
  • 52
    • 0030860597 scopus 로고    scopus 로고
    • Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and poreforming regions of NR1 and NR2 subunits
    • Kashiwagi, K.; Pahk, A. J.; Masuko, T.; Igarashi, K.; Williams, K. Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and poreforming regions of NR1 and NR2 subunits. Mol. Pharmacol. 52:701-713; 1997.
    • (1997) Mol. Pharmacol , vol.52 , pp. 701-713
    • Kashiwagi, K.1    Pahk, A.J.2    Masuko, T.3    Igarashi, K.4    Williams, K.5
  • 53
    • 0035653311 scopus 로고    scopus 로고
    • Glutamate in the enteric nervous system
    • Kirchgessner, A. L. Glutamate in the enteric nervous system. Curr. Opin. Pharmacol. 1:591-596; 2001.
    • (2001) Curr. Opin. Pharmacol , vol.1 , pp. 591-596
    • Kirchgessner, A.L.1
  • 54
    • 0028334365 scopus 로고
    • NMDA and quisqualate modulation of visceral nociception in the rat
    • Kolhekar, R.; Gebhart, G. F. NMDA and quisqualate modulation of visceral nociception in the rat. Brain Res. 651:215-226; 1994.
    • (1994) Brain Res , vol.651 , pp. 215-226
    • Kolhekar, R.1    Gebhart, G.F.2
  • 55
    • 0030008855 scopus 로고    scopus 로고
    • Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat
    • Kolhekar, R.; Gebhar, G. F. Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat. J. Neurophysiol. 75:2344-2353; 1996.
    • (1996) J. Neurophysiol , vol.75 , pp. 2344-2353
    • Kolhekar, R.1    Gebhar, G.F.2
  • 57
    • 0346967115 scopus 로고    scopus 로고
    • La, J. H.; Kim, T. W.; Sung, T. S.; Kang, J. W.; Kim, H. J.; Yang, I. S. Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. World J. Gastroenterol. 9:2791-2795; 2003.
    • La, J. H.; Kim, T. W.; Sung, T. S.; Kang, J. W.; Kim, H. J.; Yang, I. S. Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. World J. Gastroenterol. 9:2791-2795; 2003.
  • 58
    • 0029562282 scopus 로고
    • Excitability changes of somatic and viscero-somatic nociceptive reflexes in the decerebrate-spinal rabbit: Role of NMDA receptors
    • Laird, J. M.; de la Rubia, P. P.; Cervero, F. Excitability changes of somatic and viscero-somatic nociceptive reflexes in the decerebrate-spinal rabbit: Role of NMDA receptors. J. Physiol. 489(Pt. 2):545-555; 1995.
    • (1995) J. Physiol , vol.489 , Issue.PART. 2 , pp. 545-555
    • Laird, J.M.1    de la Rubia, P.P.2    Cervero, F.3
  • 59
    • 0035370250 scopus 로고    scopus 로고
    • A new model of visceral pain and referred hyperalgesia in the mouse
    • Laird, J. M.; Martinez-Caro, L.; Garcia-Nicas, E.; Cervero, F. A new model of visceral pain and referred hyperalgesia in the mouse. Pain 92:335-342; 2001.
    • (2001) Pain , vol.92 , pp. 335-342
    • Laird, J.M.1    Martinez-Caro, L.2    Garcia-Nicas, E.3    Cervero, F.4
  • 60
    • 0028576467 scopus 로고
    • Effect of fedotozine on the cardiovascular pain reflex induced by distension of the irritated colon in the anesthetized rat
    • Langlois, A.; Diop, P.; Riviere, P. J. M.; Pascaud, X.; Junien, J-L. Effect of fedotozine on the cardiovascular pain reflex induced by distension of the irritated colon in the anesthetized rat. Eur. J. Pharmacol. 271:245-251; 1994.
    • (1994) Eur. J. Pharmacol , vol.271 , pp. 245-251
    • Langlois, A.1    Diop, P.2    Riviere, P.J.M.3    Pascaud, X.4    Junien, J.-L.5
  • 61
    • 2442628592 scopus 로고    scopus 로고
    • Electrophysiological characterization of N-methyl-D-aspartate receptors in rat dorsal root ganglia neurons
    • Li, J.; McRoberts, J. A.; Nie, J.; Ennes, H. S.; Mayer, E. A. Electrophysiological characterization of N-methyl-D-aspartate receptors in rat dorsal root ganglia neurons. Pain 109:443-452; 2004.
    • (2004) Pain , vol.109 , pp. 443-452
    • Li, J.1    McRoberts, J.A.2    Nie, J.3    Ennes, H.S.4    Mayer, E.A.5
  • 63
    • 0030943255 scopus 로고    scopus 로고
    • ANDA-receptor regulation of substance P release from primary afferent nociceptors
    • Liu, H.; Mantyh, P. W.; Basbaum, A. I. ANDA-receptor regulation of substance P release from primary afferent nociceptors. Nature 386:721-724; 1997.
    • (1997) Nature , vol.386 , pp. 721-724
    • Liu, H.1    Mantyh, P.W.2    Basbaum, A.I.3
  • 64
    • 0030943255 scopus 로고    scopus 로고
    • NMDA-receptor regulation of substance P release from primary afferent nociceptors
    • Lu, H.; Mantyh, P. W.; Basbaum, A. I. NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature 386:721-724; 1997.
    • (1997) Nature , vol.386 , pp. 721-724
    • Lu, H.1    Mantyh, P.W.2    Basbaum, A.I.3
  • 65
    • 0035910321 scopus 로고    scopus 로고
    • Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem
    • Lu, Y.; Westlund, K. N. Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem. Brain Res. 889:118-130; 2001.
    • (2001) Brain Res , vol.889 , pp. 118-130
    • Lu, Y.1    Westlund, K.N.2
  • 66
    • 0028998508 scopus 로고
    • Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: Implications for the treatment of mechanical allodynia
    • Ma, Q. P.; Woolf, C. J. Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: Implications for the treatment of mechanical allodynia. Pain 61:383-390; 1995.
    • (1995) Pain , vol.61 , pp. 383-390
    • Ma, Q.P.1    Woolf, C.J.2
  • 67
    • 3042853382 scopus 로고    scopus 로고
    • The brain-gut axis in irritable bowel syndrome - clinical aspects
    • Mach, T. The brain-gut axis in irritable bowel syndrome - clinical aspects. Med. Sci. Monit. 10:RA125-RA131; 2004.
    • (2004) Med. Sci. Monit , vol.10
    • Mach, T.1
  • 68
    • 0028338434 scopus 로고
    • Basic and clinical aspects of visceral hyperalgesia
    • Mayer, E. A.; Gebhart, G. F. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 107:271-293; 1994.
    • (1994) Gastroenterology , vol.107 , pp. 271-293
    • Mayer, E.A.1    Gebhart, G.F.2
  • 69
    • 0033094051 scopus 로고    scopus 로고
    • Approaches to the modulation of abdominal pain
    • Mayer, E. A.; Lembo, T.; Chang, L. Approaches to the modulation of abdominal pain. Can. J. Gastroenterol. 13(Suppl. A):65A-70A; 1999.
    • (1999) Can. J. Gastroenterol , vol.13 , Issue.SUPPL. A
    • Mayer, E.A.1    Lembo, T.2    Chang, L.3
  • 70
    • 0032192555 scopus 로고    scopus 로고
    • Assembly intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells
    • McIlhinney, R. A.; Le Bourdelles, B.; Molnar, E.; Tricaud, N.; Streit, P.; Whiting, P. J. Assembly intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells. Neuropharmacology 37:1355-1367; 1998.
    • (1998) Neuropharmacology , vol.37 , pp. 1355-1367
    • McIlhinney, R.A.1    Le Bourdelles, B.2    Molnar, E.3    Tricaud, N.4    Streit, P.5    Whiting, P.J.6
  • 71
    • 0023205715 scopus 로고
    • A model for the study of visceral pain states: Chronic inflammation of the chronic decerebrate rat urinary bladder by irritant chemicals
    • McMahon, S. B.; Abel, C. A model for the study of visceral pain states: Chronic inflammation of the chronic decerebrate rat urinary bladder by irritant chemicals. Pain 28:109-127; 1987.
    • (1987) Pain , vol.28 , pp. 109-127
    • McMahon, S.B.1    Abel, C.2
  • 73
    • 0037358024 scopus 로고    scopus 로고
    • Review article: Visceral hypersensitivity
    • Mertz, H. Review article: Visceral hypersensitivity. Aliment Pharmacol. Ther. 17:623-633; 2003.
    • (2003) Aliment Pharmacol. Ther , vol.17 , pp. 623-633
    • Mertz, H.1
  • 74
    • 0032473367 scopus 로고    scopus 로고
    • Molecular biology of glutamate recepuors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
    • Michaelis, E. K. Molecular biology of glutamate recepuors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Prog. Neurobiol. 54:369-415; 1998.
    • (1998) Prog. Neurobiol , vol.54 , pp. 369-415
    • Michaelis, E.K.1
  • 75
    • 0024596865 scopus 로고
    • The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
    • Monaghan, D. T.; Bridges, R. J.; Cotman, C. W. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol. 29:365-402; 1989.
    • (1989) Annu. Rev. Pharmacol. Toxicol , vol.29 , pp. 365-402
    • Monaghan, D.T.1    Bridges, R.J.2    Cotman, C.W.3
  • 77
    • 12144282274 scopus 로고    scopus 로고
    • L-Aspartate-immunoreactive neurons in the rat enteric nervous system
    • Nagahama, M.; Ma, N.; Semba, R. L-Aspartate-immunoreactive neurons in the rat enteric nervous system. Cell Tissue Res. 318:483-492; 2004.
    • (2004) Cell Tissue Res , vol.318 , pp. 483-492
    • Nagahama, M.1    Ma, N.2    Semba, R.3
  • 78
    • 0026779363 scopus 로고
    • Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors
    • Nakanishi, N.; Axel, R.; Shneider, N. A. Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors. Proc. Natl. Acad. Sci. USA 89:8552-8556; 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8552-8556
    • Nakanishi, N.1    Axel, R.2    Shneider, N.A.3
  • 80
    • 0025942520 scopus 로고
    • Further behavioral evidence that colorectal distension is a "noxious" visceral stimulus in rats
    • Ness, T. J.; Randuch, A.; Gebhart, G. F. Further behavioral evidence that colorectal distension is a "noxious" visceral stimulus in rats. Neurosci. Lett. 131:113-116; 1991.
    • (1991) Neurosci. Lett , vol.131 , pp. 113-116
    • Ness, T.J.1    Randuch, A.2    Gebhart, G.F.3
  • 81
    • 0025370632 scopus 로고
    • Visceral pain: A review of experimental studies
    • Ness, T. J.; Gebhart, G. F. Visceral pain: A review of experimental studies. Pain 1:167-234; 1990.
    • (1990) Pain , vol.1 , pp. 167-234
    • Ness, T.J.1    Gebhart, G.F.2
  • 82
    • 0032102070 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate receptor clustering at excitatory synapses
    • O'Brien, R. J.; Lau, L. F.; Huganir, R. L. Molecular mechanisms of glutamate receptor clustering at excitatory synapses. Curr. Opin. Neurobiol. 8:364-369; 1998.
    • (1998) Curr. Opin. Neurobiol , vol.8 , pp. 364-369
    • O'Brien, R.J.1    Lau, L.F.2    Huganir, R.L.3
  • 83
    • 6444238582 scopus 로고    scopus 로고
    • Acute nociceptive somatic stimulus sensitizes neurons in the spinal cord to colonic distension in the rat
    • Peles, S.; Miranda, A.; Shaker, R.; Sengupta, J. N. Acute nociceptive somatic stimulus sensitizes neurons in the spinal cord to colonic distension in the rat. J. Physiol. 560(1):291-302; 2004.
    • (2004) J. Physiol , vol.560 , Issue.1 , pp. 291-302
    • Peles, S.1    Miranda, A.2    Shaker, R.3    Sengupta, J.N.4
  • 84
    • 0141458065 scopus 로고    scopus 로고
    • The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review
    • Petrenko, A. B.; Yamakura, T.; Baba, H.; Shimoji, K. The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review. Anesth. Analg. 97:1108-1116; 2003.
    • (2003) Anesth. Analg , vol.97 , pp. 1108-1116
    • Petrenko, A.B.1    Yamakura, T.2    Baba, H.3    Shimoji, K.4
  • 85
    • 20444458234 scopus 로고    scopus 로고
    • A model of neural cross-talk and irritation in the pelvis: Implications for the overlap of chronic pelvic pain disorders
    • Pezzone, M. A.; Liang, R.; Fraser, M. O. A model of neural cross-talk and irritation in the pelvis: Implications for the overlap of chronic pelvic pain disorders. Gastroenterology 128:1953-1964; 2005.
    • (2005) Gastroenterology , vol.128 , pp. 1953-1964
    • Pezzone, M.A.1    Liang, R.2    Fraser, M.O.3
  • 86
    • 0036849016 scopus 로고    scopus 로고
    • Upper thoracic respiratory interneurons integrate noxious somatic and visceral information in rats
    • Qin, C.; Chandler, M. J.; Foreman, R. D.; Farber, J. P. Upper thoracic respiratory interneurons integrate noxious somatic and visceral information in rats. J. Neurophysiol. 88:2215-2223; 2002.
    • (2002) J. Neurophysiol , vol.88 , pp. 2215-2223
    • Qin, C.1    Chandler, M.J.2    Foreman, R.D.3    Farber, J.P.4
  • 87
    • 28844497653 scopus 로고    scopus 로고
    • Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon
    • Qin, C.; Malykhina, A. P.; Akbarali, H. I.; Foreman, R. D. Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon. Gastroenterology 129:1967-1978; 2005.
    • (2005) Gastroenterology , vol.129 , pp. 1967-1978
    • Qin, C.1    Malykhina, A.P.2    Akbarali, H.I.3    Foreman, R.D.4
  • 89
    • 0033140059 scopus 로고    scopus 로고
    • Central nervous system plasticity and persistent pain
    • Ren, K.; Dubner, R. Central nervous system plasticity and persistent pain. J. Orofac. Pain 13:155-163; 1999.
    • (1999) J. Orofac. Pain , vol.13 , pp. 155-163
    • Ren, K.1    Dubner, R.2
  • 90
    • 0028229840 scopus 로고
    • Pre-emptive intrathecal administration of an NMDA receptor antagonist (AP5) prevents hyper-reflexia in a model of persistent visceral pain
    • Rice, A. S.; McMahon, S. B. Pre-emptive intrathecal administration of an NMDA receptor antagonist (AP5) prevents hyper-reflexia in a model of persistent visceral pain. Pain 57:335-340; 1994.
    • (1994) Pain , vol.57 , pp. 335-340
    • Rice, A.S.1    McMahon, S.B.2
  • 91
    • 0035341508 scopus 로고    scopus 로고
    • An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing
    • Scott, D. B.; Blanpied, T. A.; Swanson, G. T.; Zhang, C.; Ehlers, M. D. An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing. J. Neurosci. 21:3063-3072; 2001.
    • (2001) J. Neurosci , vol.21 , pp. 3063-3072
    • Scott, D.B.1    Blanpied, T.A.2    Swanson, G.T.3    Zhang, C.4    Ehlers, M.D.5
  • 92
    • 1542614144 scopus 로고    scopus 로고
    • Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors
    • Scott, D. B.; Blanpied, T. A.; Ehlers, M. D. Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors. Neuropharmacology 45:755-767; 2003.
    • (2003) Neuropharmacology , vol.45 , pp. 755-767
    • Scott, D.B.1    Blanpied, T.A.2    Ehlers, M.D.3
  • 93
    • 0027997813 scopus 로고
    • Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat
    • Sengupta, J. N.; Gebhart, G. F. Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat. J. Neurophysiol. 72:2420-2430; 1994.
    • (1994) J. Neurophysiol , vol.72 , pp. 2420-2430
    • Sengupta, J.N.1    Gebhart, G.F.2
  • 95
    • 0026768337 scopus 로고
    • Enteric and visceral afferent CGRP neurons. Targets of innervation and differential expression patterns
    • Sternini, C. Enteric and visceral afferent CGRP neurons. Targets of innervation and differential expression patterns. Ann. NY Acad. Sci. 657:170-186; 1992.
    • (1992) Ann. NY Acad. Sci , vol.657 , pp. 170-186
    • Sternini, C.1
  • 96
    • 0026766877 scopus 로고
    • Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • Sugihara, H.; Moriyoshi, K.; Ishii, T.; Masu, M.; Nakanishi, S. Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem. Biophys. Res. Commun. 185:826-832; 1992.
    • (1992) Biochem. Biophys. Res. Commun , vol.185 , pp. 826-832
    • Sugihara, H.1    Moriyoshi, K.2    Ishii, T.3    Masu, M.4    Nakanishi, S.5
  • 97
    • 0032411233 scopus 로고    scopus 로고
    • Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: Its regional distribution and developmental expression in the rat brain
    • Sun, L.; Margolis, F. L.; Shipley, M. T.; Lidow, M. S. Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: Its regional distribution and developmental expression in the rat brain. FEBS Lett. 441:392-396; 1998.
    • (1998) FEBS Lett , vol.441 , pp. 392-396
    • Sun, L.1    Margolis, F.L.2    Shipley, M.T.3    Lidow, M.S.4
  • 98
    • 14844293564 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization
    • Sun, R. Q.; Tu, Y. J.; Lawand, N. B.; Yan, J. Y.; Lin, Q.; Willis, W. D. Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. J. Neurophysiol. 92:2859-2899; 2004.
    • (2004) J. Neurophysiol , vol.92 , pp. 2859-2899
    • Sun, R.Q.1    Tu, Y.J.2    Lawand, N.B.3    Yan, J.Y.4    Lin, Q.5    Willis, W.D.6
  • 99
    • 0031040615 scopus 로고    scopus 로고
    • Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies
    • Tingley, W. G.; Ehlers, M. D.; Kameyama, K.; Doherty, C.; Ptak, J. B.; Riley, C. T.; Huganir, R. L. Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J. Biol. Chem. 272:5157-5166; 1997.
    • (1997) J. Biol. Chem , vol.272 , pp. 5157-5166
    • Tingley, W.G.1    Ehlers, M.D.2    Kameyama, K.3    Doherty, C.4    Ptak, J.B.5    Riley, C.T.6    Huganir, R.L.7
  • 100
    • 0026728502 scopus 로고
    • Fos-like proteins in the lumbosacral spinal cord following noxious and non-noxious colorectal distention in the rat
    • Traub, R. J.; Pechman, P.; Iadarola, M. J.; Gebhart, G. F. Fos-like proteins in the lumbosacral spinal cord following noxious and non-noxious colorectal distention in the rat. Pain 94:393-403; 1992.
    • (1992) Pain , vol.94 , pp. 393-403
    • Traub, R.J.1    Pechman, P.2    Iadarola, M.J.3    Gebhart, G.F.4
  • 101
    • 0033529277 scopus 로고    scopus 로고
    • Supraspinal contributions to hyperalgesia
    • Urban, M. O.; Gebhart, G. F. Supraspinal contributions to hyperalgesia. Proc. Natl. Acad. Sci. USA 96:7687-7692; 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7687-7692
    • Urban, M.O.1    Gebhart, G.F.2
  • 103
    • 0034983148 scopus 로고    scopus 로고
    • Hypersensitivity to visceral and cutaneous pain in the irritable bowel syndrome
    • Verne, G. N.; Robinson, M. E.; Price, D. D. Hypersensitivity to visceral and cutaneous pain in the irritable bowel syndrome. Pain 93:7-14; 2001.
    • (2001) Pain , vol.93 , pp. 7-14
    • Verne, G.N.1    Robinson, M.E.2    Price, D.D.3
  • 104
    • 0036674806 scopus 로고    scopus 로고
    • Irritable bowel syndrome as a common precipitant of central sensitization
    • Verne, G. N.; Price, D. D. Irritable bowel syndrome as a common precipitant of central sensitization. Curr. Rheumatol. Rep. 4(4):322-328; 2002.
    • (2002) Curr. Rheumatol. Rep , vol.4 , Issue.4 , pp. 322-328
    • Verne, G.N.1    Price, D.D.2
  • 105
    • 0141850172 scopus 로고    scopus 로고
    • Reversal of visceral and cutaneous hyperalgesia by local rectal anesthesia in irritable bowel syndrome (IBS) patients
    • Verne, G. N.; Robinson, M. E.; Vase, L.; Price, D. D. Reversal of visceral and cutaneous hyperalgesia by local rectal anesthesia in irritable bowel syndrome (IBS) patients. Pain 105:223-230; 2003.
    • (2003) Pain , vol.105 , pp. 223-230
    • Verne, G.N.1    Robinson, M.E.2    Vase, L.3    Price, D.D.4
  • 106
    • 2442703201 scopus 로고    scopus 로고
    • The role of substance P, hemokinin and their receptor in governing mucosal inflammation and granulomatous responses
    • Weinstock, J. V. The role of substance P, hemokinin and their receptor in governing mucosal inflammation and granulomatous responses. Front. Biosci. 9:1936-1943; 2004.
    • (2004) Front. Biosci , vol.9 , pp. 1936-1943
    • Weinstock, J.V.1
  • 107
    • 0032562740 scopus 로고    scopus 로고
    • Uterine inflammation as a noxious visceral stimulus: Behavioral characterization in the rat
    • Wesselmann, U.; Czakanski, P. P.; Affaitati, G.; Giamberardino, M. A. Uterine inflammation as a noxious visceral stimulus: Behavioral characterization in the rat. Neurosci. Lett. 246:73-76; 1998.
    • (1998) Neurosci. Lett , vol.246 , pp. 73-76
    • Wesselmann, U.1    Czakanski, P.P.2    Affaitati, G.3    Giamberardino, M.A.4
  • 109
    • 1542317629 scopus 로고    scopus 로고
    • The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor
    • Willert, R. P.; Woolf, C. J.; Hobson, A. R.; Delaney, C.; Thompson, D. G.; Aziz, Q. The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor. Gastroenterology 126:683-692; 2004.
    • (2004) Gastroenterology , vol.126 , pp. 683-692
    • Willert, R.P.1    Woolf, C.J.2    Hobson, A.R.3    Delaney, C.4    Thompson, D.G.5    Aziz, Q.6
  • 110
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: Implications for the treatment of post-injury pain hypersensitivity states
    • Woolf, C. J.; Thompson, S. W. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: Implications for the treatment of post-injury pain hypersensitivity states. Pain 44:293-299; 1991.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 111
    • 0034788270 scopus 로고    scopus 로고
    • An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits
    • Xia, H.; Hornby, Z. D.; Malenka, R. C. An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits. Neuropharmacology 41:714-723; 2001.
    • (2001) Neuropharmacology , vol.41 , pp. 714-723
    • Xia, H.1    Hornby, Z.D.2    Malenka, R.C.3
  • 112
    • 0032790229 scopus 로고    scopus 로고
    • Subunit- and site-specific pharmacology of the NMDA receptor channel
    • Yamakura, T.; Shimoji, K. Subunit- and site-specific pharmacology of the NMDA receptor channel. Prog. Neurobiol. 59:279-298; 1999.
    • (1999) Prog. Neurobiol , vol.59 , pp. 279-298
    • Yamakura, T.1    Shimoji, K.2
  • 113
    • 0032833183 scopus 로고    scopus 로고
    • The NMDA receptor antagonist MK-801 attenates c-Fos expression in the lumbosacral spinal cord following repetitive noxious and nonnoxious colorectal distention
    • Zhai, Q.; Traub, R. J. The NMDA receptor antagonist MK-801 attenates c-Fos expression in the lumbosacral spinal cord following repetitive noxious and nonnoxious colorectal distention. Pain 83:321-329; 1999.
    • (1999) Pain , vol.83 , pp. 321-329
    • Zhai, Q.1    Traub, R.J.2
  • 114
    • 0028207576 scopus 로고
    • Mutagenesis rescues spermine and Zn2+ potentiation of recombinant NMDA receptors
    • Zheng, X.; Zhang, L.; Durand, G. M.; Bennett, M. V.; Zukin, R. S. Mutagenesis rescues spermine and Zn2+ potentiation of recombinant NMDA receptors. Neuron 12:811-818; 1994.
    • (1994) Neuron , vol.12 , pp. 811-818
    • Zheng, X.1    Zhang, L.2    Durand, G.M.3    Bennett, M.V.4    Zukin, R.S.5
  • 115
    • 33646427493 scopus 로고    scopus 로고
    • Selective up-regulation of NMDA-NR1 receptor expression in myenteric plexus after TNBS induced colitis in rats
    • Zhou, Q.; Caudle, R. M.; Price, D. D.; Del Valle-Pinero, A. Y.; Verne, G. N. Selective up-regulation of NMDA-NR1 receptor expression in myenteric plexus after TNBS induced colitis in rats. Mol. Pain 17:2-3; 2006.
    • (2006) Mol. Pain , vol.17 , pp. 2-3
    • Zhou, Q.1    Caudle, R.M.2    Price, D.D.3    Del Valle-Pinero, A.Y.4    Verne, G.N.5
  • 116
    • 33748145974 scopus 로고    scopus 로고
    • Phosphorylation of NMDA NR1 subunits in the myenteric plexus during TNBS induced colitis
    • Zhou, Q.; Caudle, R. M.; Moshiree, B.; Price, D. D.; Verne, G. N. Phosphorylation of NMDA NR1 subunits in the myenteric plexus during TNBS induced colitis. Neurosci. Lett. 406(3):250-255; 2006.
    • (2006) Neurosci. Lett , vol.406 , Issue.3 , pp. 250-255
    • Zhou, Q.1    Caudle, R.M.2    Moshiree, B.3    Price, D.D.4    Verne, G.N.5
  • 118
    • 40949134895 scopus 로고    scopus 로고
    • Zhou, Q.; Price, D. D.; Caudle, R. M.; Verne, G. N. Visceral and somatic hypersensitivity after TNBS-induced colitis in rats. Dig. Dis. Sci.; 2007.
    • Zhou, Q.; Price, D. D.; Caudle, R. M.; Verne, G. N. Visceral and somatic hypersensitivity after TNBS-induced colitis in rats. Dig. Dis. Sci.; 2007.
  • 119
    • 0028931333 scopus 로고
    • Visceral perception in irritable bowel syndrome. Rectal and gastric responses to distension and serotonin type 3 antagonism
    • Zighelboim, J.; Talley, N. J.; Phillips, S. F.; Harmsen, W. S.; Zinsmeister, A. R. Visceral perception in irritable bowel syndrome. Rectal and gastric responses to distension and serotonin type 3 antagonism. Dig. Dis. Sci. 40:819-827; 1995.
    • (1995) Dig. Dis. Sci , vol.40 , pp. 819-827
    • Zighelboim, J.1    Talley, N.J.2    Phillips, S.F.3    Harmsen, W.S.4    Zinsmeister, A.R.5
  • 120
    • 0034666110 scopus 로고    scopus 로고
    • Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats
    • Zou, X.; Lin, Q.; Willis, W. D. Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats. J. Neurosci. 20:6989-6997; 2000.
    • (2000) J. Neurosci , vol.20 , pp. 6989-6997
    • Zou, X.1    Lin, Q.2    Willis, W.D.3
  • 121
    • 0029073172 scopus 로고
    • Alternatively spliced isoforms of the NMDARI receptor subunit
    • Zukin, R. S.; Bennett, M. V. Alternatively spliced isoforms of the NMDARI receptor subunit. Trends Neurosci. 18:306-313; 1995.
    • (1995) Trends Neurosci , vol.18 , pp. 306-313
    • Zukin, R.S.1    Bennett, M.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.