Vitamin K2-Mediated Apoptosis in Cancer Cells: Role of Mitochondrial Transmembrane Potential

Vitamins and Hormones

Volumn 78, Issue , 2008, Pages 211-226

  Shibayama Imazu, Toshiko ^a   Aiuchi, Toshihiro ^a   Nakaya, Kazuyasu ^b  

^a SHOWA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FARNOQUINONE;

ANIMAL; APOPTOSIS; CELL DIFFERENTIATION; DRUG EFFECT; HUMAN; LEUKEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; NEOPLASM; PATHOLOGY; PHYSIOLOGY; REVIEW; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEOPLASMS; VITAMIN K 2;

EID: 40949140060     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0083-6729(07)00010-6     Document Type: Review

References (83)

1. 2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures. Eur. J. Pharmacol. 263 (1994) 181-185
2. Antonsson B., Montessuit S., Lauper S., Eskes R., and Martinou J.-C. Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria. Biochem. J. 345 (2000) 271-278
3. Barry M.A., Behnke C.A., and Eastman A. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxin and hyperthermia. Biochem. Pharmacol. 40 (1990) 2353-2362
4. Bernardi P., Vassanelli S., Veronese P., Colonna R., Szabo I., and Zoratti M. Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations. J. Biol. Chem. 267 (1992) 2934-2939
5. Bertrand R., Solary E., Jenkins J., and Pommier Y. Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors. Exp. Cell Res. 207 (1993) 388-397
6. 31P nuclear magnetic resonance. Biochemistry 24 (1985) 3821-3826
7. Bouzahzah B., Nishikawa Y., Simon D., and Carr B.I. Growth control and gene expression in new hepatocellular carcinoma cell line, Hep40: Inhibitory actions of vitamin K. J. Cell. Physiol. 165 (1995) 459-467
8. Broekemeier K.M., Dempsey M.E., and Pfeiffer D.R. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264 (1989) 7826-7830
9. Chen Y.-C., Lin-Shiau S.-Y., and Lin J.-K. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis. J. Cell. Physiol. 177 (1998) 324-333
10. 2) by intestinal bacteria and their role in maintaining coagulation homeostasis. Prog. Food Nutr. Sci. 16 (1992) 307-343
11. Cossarizza A., Kalashnikova G., Grassilli E., Chiappelli F., Salvioli S., Capri M., Barbieri D., Troiano L., Monti D., and Franceshi C. Mitochondrial modifications during rat thymocyte apoptosis: A study at the single cell level. Exp. Cell Res. 214 (1994) 323-330
12. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 341 (1999) 233-249
13. Cross A.R. Inhibitors of the leukocyte superoxide generating oxidase: Mechanisms of action and methods for their elucidation. Free Radic. Biol. Med. 8 (1990) 71-93
14. Danial N.N., and Korsmeyer S.J. Cell death: Critical control points. Cell 116 (2004) 205-219
15. De Bleser P.J., Xu G., Rombouts K., Rogiers V., and Geerts A. Glutathione levels discriminate between oxidative stress and transforming growth factor β signaling in activated rat hepatic stellate cells. J. Biol. Chem. 274 (1999) 33881-33887
16. Fariss M.W., Chan C.B., Patel M., Van Houten B., and Orrenius S. Role of mitochondria in toxic oxidative stress. Mol. Interv. 5 (2005) 94-111
17. Finucane D.M., Waterhouse N.J., Amarante-Mendes G.P., Cotter T.G., and Green D.R. Collapse of inner mitochondrial transmembrane potential not required for apoptosis of HL-60 cells. Exp. Cell Res. 251 (2002) 166-174
18. Giron-Calle J., Zwizinski C.W., and Schmid H.H. Peroxidative damage to cardiac mitochondria. II. Immunological analysis of modified adenine nucleotide translocase. Arch. Biochem. Biophys. 315 (1994) 1-7
19. Gottlieb R.A. Mitochondria and apoptosis. Biol. Signals Recept. 10 (2001) 147-161
20. Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 (1998) 1309-1312
21. Greenlund L.T.S., Deckwerth T.L., and Johnson Jr. E.M. Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death. Neuron 14 (1995) 303-314
22. Hajnoczky G., and Hoek J.B. Mitochondrial longevity pathways. Science 315 (2007) 607-609
23. Halliwell B., and Gutteridge J.M.C. Antioxidant defences. "Free Radicals in Biology and Medicine". 3rd ed. (1998), Oxford Univ. Press, Oxford 208-219
24. 2+ ionophore-induced apoptosis in cultured rat cortical neurons. Biochem. Biophys. Res. Commun. 227 (1996) 513-518
25. 3 on hepatocellular carcinoma in vitro and in vivo. Int. J. Oncol. 26 (2005) 713-720
26. Imai H., Koumura T., Nakajima R., Nomura K., and Nakagawa Y. Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase. Biochem. J. 371 (2003) 799-809
27. 2+ -dependent production of superoxide. Int. J. Cancer 92 (2001) 518-526
28. Jing Y., Nakajo S., Xia L., Nakaya K., Fang Q., Waxman S., and Han R. Boswellic acid acetate induces differenciation and apoptosis in leukemia cell lines. Leuk. Res. 23 (1999) 43-50
29. Jones B.E., Lo C.R., Liu H., Pradhan Z., Garcia L., Srinivasan A., Valentino K.L., and Czaja M.J. Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis. Am. J. Physiol. Gastrointest. Liver Physiol. 278 (2000) G693-G699
30. Kagan V.E., Borisenko G.G., Tyurina Y.Y., Tyurin V., Jiang J., Potapovich A.I., Kini V., Amoscato A.A., and Fujii Y. Oxidative lipidomics of apoptosis: Redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine. Free Radic. Biol. Med. 37 (2004) 1963-1985
31. Karpinich N.O., Tafani M., Rothman R.J., Russo M.A., and Farber J.L. The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J. Biol. Chem. 277 (2002) 16547-16552
32. 2 inhibits osteoclastic bone resorption by inducing osteoclast apoptosis. Biochem. Biophys. Res. Commun. 220 (1996) 515-519
33. 2 in human hepatocellular carcinoma cells. Cancer Sci. 98 (2007) 431-437
34. Kaufmann S.H. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothesin, and other cytotoxic anticancer drugs: A cautionary note. Cancer Res. 49 (1989) 5870-5878
35. + prevents apoptosis in the mouse brain induced by tertiary-butylhydroperoxide. Neurosci. Lett. 206 (1996) 5-8
36. Kojima S., Nomura T., Icho T., Kajiwara Y., Kitabatake K., and Kubota K. Inhibitory effect of neopterin on NADPH-dependent superoxide-generating oxidase of rat peritoneal macrophages. FEBS Lett. 329 (1990) 125-128
37. Korsmeyer S.J., Wie M.C., Saito M., Weller S., Oh K.J., and Schlesinger P.H. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ. 10 (2000) 1166-1173
38. Kowaltowski A., and Vercesi A.E. Mitochondrial damage induced by conditions of oxidative stress. Free Radic. Biol. Med. 26 (1999) 463-471
39. Kroemer G. Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution. Cell Death Differ. 4 (1997) 443-456
40. Lenaz G. The mitochondrial production of reactive oxygen species; mechanisms and implications in human pathology. IUBMB Life 52 (2001) 159-164
41. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91 (1997) 479-489
42. Ly J.D., Grubb D.R., and Lawen A. The mitochondrial membrane potential (ΔΨm) in apoptosis; an update. Apoptosis 8 (2003) 115-128
43. Manfioletti G., Brancolini C., Avanzi G., and Schneider C. The protein encoded by a growth arrest-specific gene (gas 6) is a new member of the vitamin K-dependent proteins related to protein S, a negative co-regulator in the blood coagulation cascade. Mol. Cell. Biol. 13 (1993) 4976-4985
44. Marshansky V.N., Novgorodov S.A., and Yaguzhinsky L.S. The role of lipid peroxidation in the induction of cation transport in rat liver mitochondria. The antioxidant effect of oligomycin and dicyclohexylcarbodiimide. FEBS Lett. 158 (1983) 27-30
45. Marzo I., Brenner C., Zamzami N., Jurgensmeier J.M., Susin S.A., Vieira H.L., Prevost M.C., Xie Z., Matsuyama S., Reed J.C., and Kroemer G. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281 (1998) 2027-2031
46. Masuda Y., Nakaya M., Aiuchi T., Hashimoto S., Nakajo S., and Nakaya K. The mechanism of geranylgeraniol-induced apoptosis involves activation, by a caspase-3-like protease, of a c-jun N-terminal kinase signaling cascade and differs from mechanisms of apoptosis induced by conventional chemotherapeutic drugs. Leuk. Res. 24 (2000) 937-950
47. Massey V., Komai H., Palmer G., and Elion G.B. On the mechanism of inactivation of xanthine oxidase by allopurinol and other pyrazolo[3,4-d]pyrimidines. J. Biol. Chem. 245 (1970) 2837-2844
48. 2 in leukemia cells. Leukemia 15 (2001) 1111-1117
49. 2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: A pilot study. Cancer 106 (2006) 867-872
50. Moldovan L., and Moldovan N.I. Oxygen free radicals and redox biology of organelles. Histochem. Cell Biol. 122 (2004) 395-412
51. Moreno-Manzano V., Ishikawa Y., Lucio-Cazana J., and Kitamura M. Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-α-induced apoptosis of rat mesangial cells. J. Biol. Chem. 275 (2000) 12684-12691
52. Narita M., Shimizu S., Ito T., Chittenden T., Lutz R.J., Matsuda H., and Tsujimoto Y. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci. USA 95 (1998) 14681-14686
53. Nishikawa Y., Carr B.I., Wang M., Kar S., Finn F., Dowd P., Zheng Z.B., Kerns J., and Naganathan S. Growth inhibition of hepatoma cells induced by vitamin K and its analogs. J. Biol. Chem. 270 (1995) 28304-28310
54. 2 induced apoptosis of a novel cell line established from a patient with myelodysplastic syndrome in blastic transformation. Leukemia 13 (1999) 1399-1405
55. Nomura K., Imai H., Koumura T., Kobayashi T., and Nakagawa Y. Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hyperglycemia-induced apoptosis. Biochem. J. 351 (2000) 183-193
56. Nopp A., Lundahl J., and Stridh H. Caspase activation in the absence of mitochondrial changes in granulocyte apoptosis. Clin. Exp. Immunol. 128 (2002) 267-274
57. Ohnishi Y., Azuma Y., Sato Y., Mizuno Y., Tadakuma T., and Kizaki Y. Topoisomerase inhibitors induce apoptosis in thymocytes. Biochem. Biophys. Acta 1175 (1993) 147-154
58. 2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation. Hepatology 40 (2004) 243-251
59. Petrosillo G., Ruggiero F.M., and Paradies G. Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria. FASEB J. 17 (2003) 2202-2208
60. Poot M., Zhang Y.-Z., Kramer J.A., Wells K.S., Jones L.J., Hanzel D.K., Lugade A.G., Singer V.L., and Haugland R.P. Analysis of mitochondrial morphology and function with novel fixable fluorescent stains. J. Histochem. Cytochem. 44 (1996) 1363-1372
61. Saito M., Korsmeyer S.J., and Schlesinger P.H. BAX-dependent transport of cytochrome c reconstituted in pure liposomes. Nat. Cell Biol. 2 (2000) 553-555
62. 2: A potent inducer of differentiation of various human myeloid leukemia cell lines. Biochem. Biophys. Res. Commun. 205 (1994) 1305-1310
63. Scarlett L.J., and Murphy M.P. Release of apoptogenic proteins from the mitochondrial intermembrane space during the mitochondrial permeability transition. FEBS Lett. 418 (1997) 282-286
64. Schneider C., King R.M., and Philipson L. Genes specifically expressed at growth arrest of mammalian cells. Cell 54 (1998) 787-793
65. Shibayama-Imazu, T., Fujisawa, F., Masuda, M., Aiuchi, T., Nakajo, S., Itabe, H., and Nakaya, K. Induction of apoptosis in PA-1 ovarian cancer cells by vitamin K2 is associated with an increase in the level of TR3/Nur77 and its accumulation in mitochondria and nuclei. J. Cancer Res. Clin. Oncol. in press.
66. 2 selectively induced apoptosis in ovarian TYK-nu and pancreatic MIAPaCa-2 cells out of eight solid tumor cell lines through a mechanism different from geranylgeraniol. J. Cancer Res. Clin. Oncol. 129 (2003) 1-11
67. 2 trigger apoptosis in human ovarian cancer TYK-nu cells. Apoptosis 11 (2006) 1535-1543
68. Shidoji Y., Hayashi K., Komura S., Ohishi N., and Yagi K. Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation. Biochem. Biophys. Res. Commun. 264 (1999) 343-347
69. Shimizu S., Ide T., Yanagida T., and Tsujimoto Y. Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c. J. Biol. Chem. 275 (2000) 12321-12325
70. Shimizu S., Matsuoka Y., Shinohara Y., Yoneda Y., and Tsujimoto Y. Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells. J. Cell Biol. 22 (2001) 237-250
71. 2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J. Bone Miner. Res. 15 (2000) 515-521
72. 2 analog. Int. J. Hematol. 69 (1999) 24-26
73. 2+ ionophore-induced apoptosis in cultured rat cortical neurons. Brain Res. 652 (1994) 65-70
74. 2-induced antitumor effects via cell-cycle arrest and apoptosis in gastric cancer cell lines. Int. J. Mol. Med. 17 (2006) 235-243
75. Touminen E.K., Wallace C.J., and Kinnunen P.K. Phospholipid-cytochrome c interaction: Evidence for the extended lipid anchorage. J. Biol. Chem. 277 (2002) 8822-8826
76. 2-induced apoptosis of myeloma cells. Haematologia 91 (2006) 613-619
77. Turrens J.F. Superoxide production by the mitochondrial respiratory chain. Biosci. Rep. 17 (1997) 3-8
78. Wang Z., Wang M., Finn F., and Carr B.I. The growth-inhibitory effects of vitamin K and their actions on gene expression. Hepatology 22 (1995) 876-882
79. 2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid. Leukemia 11 (1997) 779-787
80. 2 selectively induces apoptosis of blastic cells in myelodysplastic syndrome: Flow cytometric detection of apoptotic cells using APO2.7 monoclonal antibody. Leukemia 12 (1998) 1392-1397
81. Yang J.C., and Cortopassi G.A. Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c. Free Radic. Biol. Med. 24 (1998) 624-631
82. 2 therapy for lung cancer. Int. J. Oncol. 23 (2003) 627-632
83. Zou H., Li Y., Liu X., and Wang X. An APAF-1ċcytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274 (1999) 11549-11556