The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-κB

Molecular and Cellular Biochemistry

Volumn 194, Issue 1-2, 1999, Pages 63-70

  Shi, Xianglin ^a   Dong, Zigang ^b   Huang, Chuanshu ^b   Ma, Weiya ^b   Liu, Kejian ^c   Ye, Jianping ^a   Chen, Fei ^a   Leonard, Stephen S ^a   Ding, Min ^a   Castranova, Vince ^a   Vallyathan, Val ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Hydroxyl radical; Messenger; NF B activation

Indexed keywords

CATALASE; CHROMIUM; FORMATE SODIUM; FORMIC ACID; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE; OXYGEN; PENTETIC ACID; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ZINC OXIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; IRRADIATION; LEUKEMIA CELL LINE; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXIDATIVE STRESS;

ANIMALS; BASE SEQUENCE; CELL LINE; CHROMIUM; DNA PRIMERS; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROXYL RADICAL; JURKAT CELLS; MICE; NF-KAPPA B; SILICON DIOXIDE; ZINC OXIDE;

ANIMALIA;

EID: 0033024459     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006904904514     Document Type: Article

References (30)

1. Baeuerle PA, Henkel T: Function and activation of NF-κB in the immune system. Annu Rev Immunol 12: 141-179, 1994
2. Baldwin AS: The NF-κB and IκB proteins: New discoveries and insights. Annu Rev Immunol 14: 649-681, 1996
3. Schreck R, Alberman K, Baeuerle PA: Nuclear factor κB: An oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Rad Res Commun 17: 221-237, 1992
4. Sun Y, Oberley LW: Redox regulation of transcriptional activators. Free Rad Biol Med 21: 335-348, 1996
5. Sen CK, Packer L: Antioxidant and redox regulation of gene transcription. FASEB J 10: 709-720, 1996
6. Suzuki YJ, Forman HJ: Oxidants as stimulators of signal transduction. Free Radical Biol Med 22: 269-285, 1997
7. Schreck R, Rieber P, Baeuerle PA: Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J 10: 2247-2258, 1991
8. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 12: 2005-2015, 1993
9. Freemam BA, Crapo JD: Biology of disease: Free radicals and tissue injury. Lab Invest 47: 412-426, 1982
10. Schmidt KN, Amstad P, Cerutti P, Baeuerle PA: The role of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB. Curr Biol 2: 13-22, 1995
11. Schulze-Osthoff, K, Beyaert R, Vandevoorde V, Haegeman G, Fiers W: Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J 12: 3095-3104, 1993
12. Schulze-Osthoff K, Bakker AC, VanhaesebroeckB, Beyaert R, Jacob WA, Fiers W: Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. J Biol Chem 267: 587-592, 1992
13. Schreck R, Baeuerle PA: Oxygen radicals as mediators in the activation of inducible eukaryotic transcription factor NF-κB. Meth Enzymol 234: 151-163, 1994
14. Israel N, Gougerot-Pocidalo MA, Aillet F, Virelizier JL: Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines. J Immunol 149: 3386-3393, 1992
15. Anderson MT, Staal FJT, Gitler C, Herzenberg LA: Separation of oxidant-initiated and redox-regulated steps in the NF-κB signal transduction pathway. Proc Natl Acad Sci USA 91: 11527-11531, 1994
16. Suzuki YJ, Mizurto M, Packer L: Transient overexpression of catalase does not inhibit TNF- or PMA-induced NF-kappa B activation. Biochem Biophys Res Commun 210: 537-541, 1995
17. Sies H: Strategies of antioxidant defense. Eur J Biochem 21: 213-219, 1993
18. Ye J, Zhang X, Young HA, Mao Y, Shi X: Chromium(VI)-induced nuclear factor-κB activation in intact cells via free radical reactions. Carcinogenesis 16: 2401-2405, 1995
19. Dong Z, Craw HC, Lavrovsky V, Taub D, Watts R, Matrisian LM, Cobburn NH: A dominant negative mutant of jun blocking 12-o-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. Mol Carcinogenesis 19: 204-212, 1997
20. Sun SC, Elwood J, Beraud C, Greene WC: Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B and RelA(p65)-mediated induction of the c-rel gene. Mol Cell Biol 14: 7377-7384, 1994
21. Shi X, Dalal NS: On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species. Arch Biochem Biophys 277: 342-350, 1990
22. Shi X, Mao, Y, Knapton AD, Ding M, Rojanasakul R, Gannett PM, Dalal NS, Liu KJ: Reduction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: Role of a Cr(IV)-mediated Fenton-like reaction. Carcinogenesis 15: 2475-2478, 1994
23. Shi X Dalal NS: Role of superoxide radical in chromium(VI)-generated hydroxyl radical: The Cr(VI) Haber-Weiss cycle. Arch Biochem Biophys 292: 325-327, 1992
24. Buettner GR: ESR parameters of spin adducts. Free Rad Biol Med 3: 259-303, 1987
25. Vallyathan V, Shi, X, Dalal NS, Irr W, Castranova V: Generation of free radical from freshly fractured silica dust. Potential role in acute silica-induced lung injury. Am Rev Resp Dis 138: 1213-1219, 1988
26. Vallyathan V, Mega JF, Shi X, Dalal NS: Enhanced generation of free radicals from phagocytes induced by mineral dusts. Am J Resp Cell Mol Dis 6: 404-413, 1992
27. Chen F, Sun SC, Kuh DC, Gaydos U, Demers LM: Essential role of NF-κB activation in silica-induced inflammatory mediator production in macrophages. Biochem Biophys Res Commun 214: 985-992, 1995
28. Chen F, Kuh DC, Sun SC, Gaydos U, Demers LM: Dependence and reversal of nitric oxide production on NF-KB in silica and lipopolysaccharide-inducedmacrophages. Biochem Biophys Res Commun 214: 839-846, 1995
29. Shi X, Dalal NS: NADPH-dependent flavoenzymes catalyze one electron reduction of metal ions and molecular oxygen and generate hydroxyl radicals. FEBS Lett 276: 189-191, 1990
30. Ji L, Arcinas M, Boxer LM: NF-kB sites function as positive regulators of expression of the translocated c-myc allelle in Burkitt's lymphoma. Mol Cell Biol 14: 141-179, 1994