Molecular characterization of a human scavenger receptor, human MARCO

European Journal of Biochemistry

Volumn 267, Issue 3, 2000, Pages 919-926

  Elshourbagy, Nabil A ^a,b   Li, Xiaotong ^a   Terrett, John ^a   VanHorn, Stephanie ^a   Gross, Mitchell S ^a   Adamou, John E ^a   Anderson, Karen M ^a   Webb, Christine L ^a   Lysko, Paul G ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Department of Molecular Biology ^*  (United States)

Author keywords

Bacterial binding; Chromosome 2q14; MARCO; Scavenger receptor

Indexed keywords

AMINO ACID; COLLAGEN; COMPLEMENTARY DNA; LIGAND; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; NUCLEOTIDE; SCAVENGER RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; ATHEROGENESIS; CELL STRAIN COS1; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LIGAND BINDING; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL ADHESION; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; CLONING, MOLECULAR; COS CELLS; DNA PRIMERS; ESCHERICHIA COLI; FEMALE; HUMANS; MACROPHAGES; MALE; MICE; MOLECULAR SEQUENCE DATA; RECEPTORS, IMMUNOLOGIC; RECOMBINANT PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MURINAE; STAPHYLOCOCCUS AUREUS;

EID: 0033974325     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01077.x     Document Type: Article

References (27)

1. 1. Freeman, M.W. (1997) Scavenger receptors in atherosclerosis. Curr. Opin. Hematol. 4, 41-47.
2. 2. Matsumoto, A., Naito, M., Itakura, H., Ikemoto, S., Asaoka, H., Hayakawa, I., Kanamori, H., Aburatani, H., Takaku, R, Suzuki, H., Kobari, Y., Miyai, T., Takahashi, K., Cohen, E.H., Wydro, R., Housman, D.E. & Kodama, T. (1990) Human macrophage scavenger receptors: Primary structure, expression, and localization in atherosclerotic lesions. Proc. Natl Acad. Sci. USA 87, 9133-9137.
3. 3. Krieger, M. (1992) Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor. Trends Biochem. Sci. 17, 141-146.
4. 4. Gough, P.J., Greaves, D.R. & Gordon, S. (1998) A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake. J. Lipid Res. 39, 531-543.
5. 5. Freeman, M., Ashkenas, J., Rees, D.J., Kingsley, D.M., Copeland, N.G., Jenkins, N.A. & Krieger, M. (1990) An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. Proc. Natl Acad. Sci. USA 87, 8810-8814.
6. 6. Resnick, D., Pearson, A. & Krieger, M. (1994) The SRCR superfamily: a family reminiscent of the Ig superfamily. Trends Biochem. Sci. 19, 5-8.
7. 7. Doi, T., Higashino, K., Kurihara, Y., Wada, Y, Miyazaki, T., Nakamura, H., Uesugi, S., Imanishi, T., Kawabe, Y., Itakura, H., Yazaki, Y., Matsumoto, A. & Kodama, T. (1993) Charged collagen structure mediates the recognition of negatively charged macro-molecules by macrophage scavenger receptors. J. Biol. Chem. 268, 2126-2133.
8. 8. Andersson, L. & Freeman, M. (1998) Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain. J. Biol. Chem. 273, 19592-19601.
9. 9. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I., Kraal, G. & Tryggvason, K. (1995) Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80, 603-609.
10. 10. Elomaa, O., Sankala, M., Pikkarainen, T., Bergmann, U., Tuuttila, A., Raatikainen-Ahokas, A., Sariola, H. & Tryggvason, K. (1998) Structure of the human MARCO receptor and characterization of its bacteria-binding region. J. Biol. Chem. 273, 4530-4538.
11. 11. Lysko, P.O., Weinstock, J., Webb, C.L., Brawner, M.E. & Elshourbagy, N.A. (1999) Identification of a small-molecule, nonpeptide macrophage scavenger receptor antagonist. J. Pharmacol. Exp. Ther. 289, 1277-1285.
12. 12. Adams, M.D., Kelley, J.M., Gocayne, J.D., Dubnick, M., Polymeropoulos, M.H., Xiao, H., Merril, C.R., Wu, A., Olde, B., Moreno, R.F., Kerlavage, A.R., McCombie, W.R. & Venter, J.C. (1991) Complementary DNA sequencing: expressed sequence tags and human genome project. Science 252, 1651-1656.
13. 13. Adams, M.D., Dubnick, M., Kerlavage, A.R., Moreno, R.F., Kelley, J.M., Utterback, T.R., Nagle, J.W., Fields, C. & Venter, J.C. (1992) Sequence identification of 2,375 human brain genes. Nature (London) 355, 632-634.
14. 14. Adams, M.D., Kerlavage, A.R., Fleischmann, R.D., Fuldner, R.A., Bull, C.J., Lee, N.H., Kirkness, E.F., Weinstock, K.G., Gocayne, J.D., White, O., Sutton, G., Slake, J.A., Brandon, R.C., Chiu, M.-W., Clayton, R.A., Cline, R.T., Cofton, M.D., Earle-Hughes, J., Fine, L.D., FitzGerald, L.M., FitzHugh, W.M., Fritchman, J.L., Geoghegan, N.S.M., Giodek, A., Gnehm, C.L., Hanna, M.C., Hodblom, E., Hinkle, P.S. Jr, Kelley, J.M., Klimek, K.M., Kelley, J.C., Liu, L.-I., Marmaros, S.M., Merrick, J.M., Moreno-Palanques, R.F., McDonald, L.A., Nguyen, D.T., Pellegrino, S.M., Phillips, C.A., Ryder, S.E., Scott, J.L., Saudek, D.M., Shirley, R., Small, K.V., Spriggs, T.A., Utterback, T.R., Weidman, J.F., Li, Y., Barthlow, R., Bednarik, D.P., Coo, L., Copeda, M.A., Coleman, T.A., Collins, E.-J., Dimke, D., Fang, P., Ferris, A., Fischer, C., Hastings, G.A., He, W.-W., Hu, J.-S., Huddleston, K.A., Greene, J.M., Gruber, J., Hudson, P., Kim, A., Kozak, D.L., Kunsch, C., Ji, H., Li, H., Moissner, P.S., Oison, H., Raymond, L., Wei, Y.-F., Wing, J., Xu, C., Yu, Q.-L., Ruben, S.M., Dillon, P.J., Fannon, M.R., Rosen, C.A., Haseltine, W.A., Fields, C., Fraser, C.M. & Venter, J.C. (1995) Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature (London) 377 (Suppl.), 3-174.
15. 15. Chomezynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
16. 16. Gyapay, G., Schmitt, K., Fizames, C., Jones, H., Vega-Czarny, N., Spillet, D., Muselet, D., Prud'Homme, J.F., Dib, C., Auffray, C., Morissette, J., Weissenbach, J. & Goodfellow, P. (1996) A radiation hybrid map of the human genome. Hum. Mol. Gen. 5, 339-346.
17. 17. Hudson, T., Stein, L., Gerety, S., Ma, J., Castle, A., Suva, J., Slonim, D., Baptista, R., Kruglyak, L., Xu, S., Hu, X., Colbert, A., Rosenberg, C., Reeve-Daly, M.P., Rozen, S., Hui, L., Wu, X., Vestergaard, C., Wilson, K., Bae, J., Maitra, S., Ganiatsas, S., Evans, C., DeAngelis, M., Ingalls, K., Nahf, R., Horton, L., Oskin, M., Collymore, A., Ye, W., Kouyoumjian, V, Zernsteva, L, Tarn, J., Devine, R., Courtney, D., Renaud, M., Nguyen, H., O'Connor, T., Fizames, C., Faure, S., Gyapay, G., Dib, C., Morissette, J., Orlin, J., Birren, B., Goodman, N., Weissenbach, J., Hawkins, T., Foote, S., Page, D. & Lander, E. (1995) An STS-based map of the human genome. Science 270, 1945-1954.
18. 18. Aiyar, N., Baker, E., Wu, H.-L., Nambi, P., Edwards, R.M., Trill, J.J., Ellis, C. & Bergsma, D.J. (1994) Human ATI receptor is a single copy gene: characterization in a stable cell line. Mol. Cell. Biochem. 131, 75-86.
19. 19. Freeman, M.W. (1994) Macrophage scavenger receptors. Curr. Opin. Lipidol. 5, 143-148.
20. 20. van der Laan, L.J., Dopp, E.A., Haworth, R., Pikkarainen, T., Kangas, M., Elomaa, O., Dijkstra, C.D., Gordon, S., Tryggvason, K. & Kraal, G. (1999) Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo. J. Immunol. 162, 939-947.
21. 21. van der Laan, L.J.W., Kangas, M., Dopp, E.A., Brougholub, E., Elomaa, O., Tryggvason, K. & Kraal, G. (1997) Macrophage scavenger receptor MARCO: in vitro and in vivo regulation and involvement in the anti-bacterial host defense. Immunol. Lett. 57, 203-208.
22. 22. Schuler, G.D., Boguski, M.S., Stewart, E.A., Stein, L.D., Gyapay, G., Rice, K., White, R.E., Rodriguez-Tome, P., Aggarwal, A., Bajorek, E., Bentolila, S., Birren, B.B., Butler, A., Castle, A.B., Chiannilkulchai, N., Chu, A., Clee, C., Cowles, S., Day, P.J., Dibling, T., Drouot, N., Dunham, I., Duprat, S., East, C., Edwards, C., Fan, J.-B., Fang, N., Fizames, C., Garrett, C., Green, L., Hadley, D., Harris, M., Harrison, P., Brady, S., Hicks, A., Holloway, E., Hui, L., Hussain, S., Louis-Dit-Sully, C., Ma, J., MacGilvery, A., Mader, C., Maratukulam, A., Matise, T.C., McKusick, K.B., Morissette, J., Mungall, A., Muselet, D., Nusbaum, H.C., Page, D.C., Peck, A., Perkins, S., Piercy, M., Qin, F., Quackenbush, J., Ranby, S., Reif, T., Rozen, S., Sanders, C., She, X., Suva, J., Slonim, O.K., Soderlund, C., Sun, W.-L., Tabar, P., Thangarajah, T., Vega-Czarny, N., Vollrath, D., Voyticky, S., Wilmer, T., Wu, X., Adams, M.D., Auffray, C., Walter, N.A.R., Brandon, R., Dehejia, A., Goodfellow, P.N., Houlgatte, R., Hudson, J.R. Jr, Ide, S.E., Iorio, K.R., Lee, W.Y., Seki, N., Nagase, T., Ishikawa, K., Nomura, N., Phillips, C., Polymeropoulos, M.H., Sandusky, M., Schmitt, K., Berry, R., Swanson, K., Torres, R., Venter, J.C., Sikela, J.M., Beckmann, J.S., Weissenbach, J., Myers, R.M., Cox, D.R., James, M.R., Bentley, D., Deloukas, P., Lander, E.S. & Hudson, T.J. (1996) A gene map of the human genome. Science 274, 540-546.
23. 23. Hampton, R.Y., Golenbock, D.T., Penman, M., Krieger, M. & Raetz, C.R.H. (1991) Recognition and plasma clearance of endotoxin by scavenger receptors. Nature (London) 352, 342-344.
24. 24. Resnick, D., Chatterton, J.E., Schwartz, K., Slayter, H. & Krieger, K. (1996) Structure of class A macrophage scavenger receptors. J. Biol. Chem. 271, 26924-26930.
25. 25. Sakaguchi, H., Takeya, M., Suzuki, H., Hakamata, H., Kodama, T., Horiuchi, S., Gordon, S., van der Laan, L.J.W., Kraal, G., Ishibashi, S., Kitamura, N. & Takahashi, K. (1998) Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice. Lab. Invest. 78, 423-434.
26. 26. Ito, S., Naito, M., Kobayashi, Y., Takatsuka, H., Jiang, S., Usuda, H., Umezu, H., Hasegawa, G., Arakawa, M., Shultz, L.D., Elomaa, O. & Tryggvason, K. (1999) Roles of a macrophage receptor with collagenous structure (MARCO) in host defense and heterogeneity of splenic marginal zone macrophages. Arch. Histol. Cytol. 62, 83-95.
27. 27. Qiao, J.H., Tripathi, J., Mishra, N.K., Cai, Y., Tripathi, S., Wang, X.P., Imes, S., Fishbein, M.C., Clinton, S.K., Libby, P., Lusis, A.J. & Rajavashisth, T.B. (1997) Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice. Am. J. Pathol. 150, 1687-1699.