Synthesis and evaluation of [123I]labelled analogues of the partial inverse agonist Ro 15-4513 for the study of diazepam-insensitive benzodiazepine receptors

Nuclear Medicine and Biology

Volumn 26, Issue 6, 1999, Pages 641-649

  Katsifis, Andrew ^a   Mardon, Karine ^a   McPhee, Meredith ^b   Mattner, Filomena ^a   Dikic, Branko ^a   Ridley, Damon ^b  

^a Forest R and D Division   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

123I Ligands; Benzodiazepine receptor; Diazepam insensitive; Diazepam sensitive

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINE RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; AZIDE; DIAGNOSTIC AGENT; DIAZEPAM; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN MEMBRANE; CEREBELLUM; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; HIPPOCAMPUS; LIGAND BINDING; NONHUMAN; RADIOCHEMISTRY; RAT; RECEPTOR BINDING; ANIMAL; BRAIN; CHEMICAL STRUCTURE; DRUG EFFECT; METABOLISM; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; AUTORADIOGRAPHY; AZIDES; BENZODIAZEPINES; BRAIN; DIAZEPAM; FEMALE; INDICATORS AND REAGENTS; IODINE RADIOISOTOPES; MOLECULAR STRUCTURE; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 0032590037     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00030-X     Document Type: Article

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