메뉴 건너뛰기




Volumn 68, Issue 6, 1997, Pages 967-976

Mifepristone (RU486): A review

Author keywords

Abortifacient; Antiprogestins; Breast cancer; Cervical ripening; Contraceptive; Endometriosis; Labor induction; Leiomyoma; Mifepristone; RU486

Indexed keywords

GLUCOCORTICOID RECEPTOR; MIFEPRISTONE;

EID: 0031437016     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)00189-1     Document Type: Article
Times cited : (142)

References (80)
  • 2
    • 0019443088 scopus 로고
    • Regio and stereospecific synthesis of 11β-substituted 19-norsteroids
    • 2. Belanger A, Philibert D, Teutsch G. Regio and stereospecific synthesis of 11β-substituted 19-norsteroids. Steroids 1981; 37:361-82.
    • (1981) Steroids , vol.37 , pp. 361-382
    • Belanger, A.1    Philibert, D.2    Teutsch, G.3
  • 3
    • 0025239785 scopus 로고
    • Two distinct estrogen regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • 3. Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, et al. Two distinct estrogen regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 1990; 9:1603-14.
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6
  • 4
    • 0025329841 scopus 로고
    • Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
    • 4. Fawell SE, Lees JA, White R, Parker MG. Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor. Cell 1990;60:953-62.
    • (1990) Cell , vol.60 , pp. 953-962
    • Fawell, S.E.1    Lees, J.A.2    White, R.3    Parker, M.G.4
  • 5
    • 0026404631 scopus 로고
    • On the mechanism of action of RU486
    • Seppala M, Hamberger L, editors. Frontiers in human reproduction
    • 5. Baulieu EE. On the mechanism of action of RU486. In: Seppala M, Hamberger L, editors. Frontiers in human reproduction. Ann NY Acad Sci 1991;626:545-6.
    • (1991) Ann NY Acad Sci , vol.626 , pp. 545-546
    • Baulieu, E.E.1
  • 6
    • 0024508880 scopus 로고
    • Phosphotryptic peptide analysis of human progesterone receptor: New phosphorylated sites formed in nuclei after hormone treatment
    • 6. Sheridan PL, Evans RM, Horwitz KB. Phosphotryptic peptide analysis of human progesterone receptor: new phosphorylated sites formed in nuclei after hormone treatment. J Biol Chem 1989;264:6520-8.
    • (1989) J Biol Chem , vol.264 , pp. 6520-6528
    • Sheridan, P.L.1    Evans, R.M.2    Horwitz, K.B.3
  • 7
    • 0026322726 scopus 로고
    • Differences in the binding mechanism of RU486 and progesterone to the progesterone receptors
    • 7. Skafar DF. Differences in the binding mechanism of RU486 and progesterone to the progesterone receptors. Biochemistry 1991;30:10829-31.
    • (1991) Biochemistry , vol.30 , pp. 10829-10831
    • Skafar, D.F.1
  • 9
    • 0023001249 scopus 로고
    • Plasma levels of antiprogestin RU486 following oral administration to non-pregnant and early pregnant women
    • 9. Swahn ML, Wang G, Aedo AR, Cekan SZ, Bygdeman M, Plasma levels of antiprogestin RU486 following oral administration to non-pregnant and early pregnant women. Contraception 1986;34:469-81.
    • (1986) Contraception , vol.34 , pp. 469-481
    • Swahn, M.L.1    Wang, G.2    Aedo, A.R.3    Cekan, S.Z.4    Bygdeman, M.5
  • 11
    • 0022365639 scopus 로고
    • Transplacental passage of mifepristone
    • 11. Frydman R, Taylor S, Ulmann A. Transplacental passage of mifepristone. Lancet 1985;2:1252.
    • (1985) Lancet , vol.2 , pp. 1252
    • Frydman, R.1    Taylor, S.2    Ulmann, A.3
  • 12
    • 0025316356 scopus 로고
    • The placental transfer of mifepristone (RU486) during the second trimester and its influence upon maternal and fetal steroid concentrations
    • 12. Hill NCW, Selinger M, Ferguson J, MacKenzie IZ. The placental transfer of mifepristone (RU486) during the second trimester and its influence upon maternal and fetal steroid concentrations. Br J Obstet Gynaecol 1990;97:406-11.
    • (1990) Br J Obstet Gynaecol , vol.97 , pp. 406-411
    • Hill, N.C.W.1    Selinger, M.2    Ferguson, J.3    MacKenzie, I.Z.4
  • 13
    • 0025347161 scopus 로고
    • Effect of antiprogesterone RU486 in early follicular phase of the menstrual cycle
    • 13. Stuenkel CA, Garzo VG, Morris S, Liu JH, Yen SSC. Effect of antiprogesterone RU486 in early follicular phase of the menstrual cycle. Fertil Steril 1990;53:642-6.
    • (1990) Fertil Steril , vol.53 , pp. 642-646
    • Stuenkel, C.A.1    Garzo, V.G.2    Morris, S.3    Liu, J.H.4    Yen, S.S.C.5
  • 14
    • 0023571530 scopus 로고
    • Disruption of follicular maturation and delay of ovulation after administration of antiprogesterone RU486
    • 14. Liu JH, Garzo VG, Morris S, Stuenkel CA, Ulmann A, Yen SSC. Disruption of follicular maturation and delay of ovulation after administration of antiprogesterone RU486. J Clin Endocrinol Metab 1987;65:1135-40.
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 1135-1140
    • Liu, J.H.1    Garzo, V.G.2    Morris, S.3    Stuenkel, C.A.4    Ulmann, A.5    Yen, S.S.C.6
  • 15
    • 0023579662 scopus 로고
    • Effect of antiprogesterone RU486 in normal women. II. Administration in the late follicular phase
    • 15. Shoupe D, Mishell DR, Page MA, Madkour H, Spitz IM, Lobo RA. Effect of antiprogesterone RU486 in normal women. II. Administration in the late follicular phase. Am J Obstet Gynecol 1987;157:1421-6.
    • (1987) Am J Obstet Gynecol , vol.157 , pp. 1421-1426
    • Shoupe, D.1    Mishell, D.R.2    Page, M.A.3    Madkour, H.4    Spitz, I.M.5    Lobo, R.A.6
  • 16
    • 0023914163 scopus 로고
    • Inhibition of folliculogenesis and ovulation by the antiprogesterone RU486
    • 16. Luukkainen T, Heikinheimo O, Haukkamaa M, Lahteenmaki P. Inhibition of folliculogenesis and ovulation by the antiprogesterone RU486. Fertil Steril 1988;49:961-8.
    • (1988) Fertil Steril , vol.49 , pp. 961-968
    • Luukkainen, T.1    Heikinheimo, O.2    Haukkamaa, M.3    Lahteenmaki, P.4
  • 17
    • 0024565356 scopus 로고
    • Acute effect of progesterone and the antiprogestin RU486 on gonadotropin secretion in the follicular phase of the menstrual cycle
    • 17. Permezel JM, Lenton EA, Roberts I, Cooke ID. Acute effect of progesterone and the antiprogestin RU486 on gonadotropin secretion in the follicular phase of the menstrual cycle. J Clin Endocrinol Metab 1989;68:960-5.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 960-965
    • Permezel, J.M.1    Lenton, E.A.2    Roberts, I.3    Cooke, I.D.4
  • 18
    • 0028361063 scopus 로고
    • The antiprogestin RU486 delays the midcycle surge and ovulation in gonadotropin releasing hormone-induced cycles
    • 18. Batista MC, Cartledge TP, Zellmer AW, Nieman LK, Loriaux DL, Merriam GR. The antiprogestin RU486 delays the midcycle surge and ovulation in gonadotropin releasing hormone-induced cycles. Fertil Steril 1994;62:28-34.
    • (1994) Fertil Steril , vol.62 , pp. 28-34
    • Batista, M.C.1    Cartledge, T.P.2    Zellmer, A.W.3    Nieman, L.K.4    Loriaux, D.L.5    Merriam, G.R.6
  • 19
    • 0027394348 scopus 로고
    • Mifepristone: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential
    • 19. Brogden RN, Goa KL, Faulds D. Mifepristone: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential. Drugs 1993;45:384-409.
    • (1993) Drugs , vol.45 , pp. 384-409
    • Brogden, R.N.1    Goa, K.L.2    Faulds, D.3
  • 20
    • 0023617190 scopus 로고
    • Early pregnancy termination with anti-progestin: A comparative clinical study of RU486 given in two dose regimens and Epostane
    • 20. Birgerson L, Odlind V. Early pregnancy termination with anti-progestin: a comparative clinical study of RU486 given in two dose regimens and Epostane. Fertil Steril 1987;48: 565-70.
    • (1987) Fertil Steril , vol.48 , pp. 565-570
    • Birgerson, L.1    Odlind, V.2
  • 21
    • 0021243911 scopus 로고
    • Termination of very early pregnancy by RU486 - An antiprogestational compound
    • 21. Kovacs L, Sas M, Resch BA, Ugocsai G, Swahn ML, Bygdeman M, et al. Termination of very early pregnancy by RU486 - an antiprogestational compound. Contraception 1984;29:399-409.
    • (1984) Contraception , vol.29 , pp. 399-409
    • Kovacs, L.1    Sas, M.2    Resch, B.A.3    Ugocsai, G.4    Swahn, M.L.5    Bygdeman, M.6
  • 23
    • 0022396986 scopus 로고
    • Preliminary results with the antiprogestational compound RU486 (mifepristone) for interruption of early pregnancy
    • 23. Vervest HAM, Haspels AA. Preliminary results with the antiprogestational compound RU486 (mifepristone) for interruption of early pregnancy. Fertil Steril 1985;44:627-32.
    • (1985) Fertil Steril , vol.44 , pp. 627-632
    • Vervest, H.A.M.1    Haspels, A.A.2
  • 25
    • 0024788662 scopus 로고
    • RU486 (mifepristone) clinical trials in China
    • 25. Shu-rong Z. RU486 (mifepristone) clinical trials in China. Acta Obstet Gynecol Scand 1989;149:19-23.
    • (1989) Acta Obstet Gynecol Scand , vol.149 , pp. 19-23
    • Shu-Rong, Z.1
  • 26
    • 0021995017 scopus 로고
    • Progesterone receptor blockage. Effect on uterine contractility and early pregnancy
    • 26. Bygdeman M, Swahn ML. Progesterone receptor blockage. Effect on uterine contractility and early pregnancy. Contraception 1985;32:45-51.
    • (1985) Contraception , vol.32 , pp. 45-51
    • Bygdeman, M.1    Swahn, M.L.2
  • 27
    • 0023037936 scopus 로고
    • Therapeutic abortion in early pregnancy with antiprogesterone RU486 alone or in combination with prostaglandin analog (Gerneprost)
    • 27. Cameron IT, Michie AF, Baird DT. Therapeutic abortion in early pregnancy with antiprogesterone RU486 alone or in combination with prostaglandin analog (Gerneprost). Contraception 1986;34:459-68.
    • (1986) Contraception , vol.34 , pp. 459-468
    • Cameron, I.T.1    Michie, A.F.2    Baird, D.T.3
  • 28
    • 0023475341 scopus 로고
    • Induction of therapeutic abortion in early pregnancy with mifepristone in combination with prostaglandin pessary
    • 28. Rodger MW, Baird DT. Induction of therapeutic abortion in early pregnancy with mifepristone in combination with prostaglandin pessary. Lancet 1987;2:1415-8.
    • (1987) Lancet , vol.2 , pp. 1415-1418
    • Rodger, M.W.1    Baird, D.T.2
  • 30
    • 0025159060 scopus 로고
    • 1 analogue vaginal pessary for the termination of early pregnancy: Complication and patients' acceptability
    • 1 analogue vaginal pessary for the termination of early pregnancy: complication and patients' acceptability. Am J Obstet Gynecol 1990;162:414-7.
    • (1990) Am J Obstet Gynecol , vol.162 , pp. 414-417
    • Hill, N.C.W.1    Ferguson, J.2    Mackenzie, I.Z.3
  • 32
    • 0010660407 scopus 로고
    • WHO suggests lower dose of mifepristone
    • 32. Maurice J. WHO suggests lower dose of mifepristone. Br Med J 1991;303:944.
    • (1991) Br Med J , vol.303 , pp. 944
    • Maurice, J.1
  • 33
    • 0025742872 scopus 로고
    • Early pregnancy termination with mifepristone and gemeprost: A multicenter comparison between repeated doses and a single dose of mifepristone
    • 33. WHO Task Force. Early pregnancy termination with mifepristone and gemeprost: a multicenter comparison between repeated doses and a single dose of mifepristone. Fertil Steril 1991;56:32-40.
    • (1991) Fertil Steril , vol.56 , pp. 32-40
  • 34
    • 0023489696 scopus 로고
    • Mifepristone (RU486) and second trimester termination
    • 34. Urquhart DR, Templeton AA. Mifepristone (RU486) and second trimester termination. Lancet 1987;2:1405-6.
    • (1987) Lancet , vol.2 , pp. 1405-1406
    • Urquhart, D.R.1    Templeton, A.A.2
  • 35
    • 0024596656 scopus 로고
    • Efficacy of the antiprogestin mifepristone (RU486) prior to prostaglandin termination of pregnancy
    • 35. Urquhart DR, Bahzad C, Templeton AA. Efficacy of the antiprogestin mifepristone (RU486) prior to prostaglandin termination of pregnancy. Hum Reprod 1989;4:202-3.
    • (1989) Hum Reprod , vol.4 , pp. 202-203
    • Urquhart, D.R.1    Bahzad, C.2    Templeton, A.A.3
  • 36
    • 0025264919 scopus 로고
    • Pretreatment with mifepristone (RU486) reduces interval between prostaglandin administration and expulsion in second trimester abortion
    • 36. Rodger MW, Baird DT. Pretreatment with mifepristone (RU486) reduces interval between prostaglandin administration and expulsion in second trimester abortion. Br J Obstet Gynaecol 1990;97:41-5.
    • (1990) Br J Obstet Gynaecol , vol.97 , pp. 41-45
    • Rodger, M.W.1    Baird, D.T.2
  • 37
    • 0025145257 scopus 로고
    • The use of mifepristone prior to prostaglandin-induced mid-trimester abortion
    • 37. Urquhart DR, Templeton AA. The use of mifepristone prior to prostaglandin-induced mid-trimester abortion. Hum Reprod 1990;5:883-6.
    • (1990) Hum Reprod , vol.5 , pp. 883-886
    • Urquhart, D.R.1    Templeton, A.A.2
  • 38
    • 0026589258 scopus 로고
    • RU486 (mifepristone) et interruption volontaire ed grossesse pour motif therapeutique an deuxieme et troisieme trimestre
    • 38. Pons JC, Rais S, Diochin P, Frydman R. RU486 (mifepristone) et interruption volontaire ed grossesse pour motif therapeutique an deuxieme et troisieme trimestre. J Gynecol Obstet Biol Reprod (Paris) 1992;21:255-7.
    • (1992) J Gynecol Obstet Biol Reprod (Paris) , vol.21 , pp. 255-257
    • Pons, J.C.1    Rais, S.2    Diochin, P.3    Frydman, R.4
  • 39
    • 0025942987 scopus 로고
    • The use of antiprogestin (RU486.) for termination of second trimester pregnancy
    • 39. Gottlieb C, Bygdeman M. The use of antiprogestin (RU486.) for termination of second trimester pregnancy. Acta Obstet Gynecol Scand 1991;70:199-203.
    • (1991) Acta Obstet Gynecol Scand , vol.70 , pp. 199-203
    • Gottlieb, C.1    Bygdeman, M.2
  • 40
    • 0026772940 scopus 로고
    • A study of gemeprost alone, dilapan or mifepristone in combination with gemeprost for termination of second trimester pregnancy
    • 40. Thong KJ, Baird DT. A study of gemeprost alone, dilapan or mifepristone in combination with gemeprost for termination of second trimester pregnancy. Contraception 1992;46:11-7.
    • (1992) Contraception , vol.46 , pp. 11-17
    • Thong, K.J.1    Baird, D.T.2
  • 41
    • 0025636475 scopus 로고
    • Cervical ripening of the rat in dependence of endocrine milieu: Effect of antiprogestins
    • 41. Stiemer B, Elger W, Cervical ripening of the rat in dependence of endocrine milieu: effect of antiprogestins. J Perinat Med 1990;18:419-29.
    • (1990) J Perinat Med , vol.18 , pp. 419-429
    • Stiemer, B.1    Elger, W.2
  • 42
    • 0025904943 scopus 로고
    • Induction of labor and cervical maturation using mifepristone (RU486) in the late pregnant rat. Influence of a cyclooxygenase inhibitor (Diclofenac)
    • 42. Cabrol D, Carbonne B, Bienkiewicz A, Dallat E, Alj AE, Cedard L. Induction of labor and cervical maturation using mifepristone (RU486) in the late pregnant rat. Influence of a cyclooxygenase inhibitor (Diclofenac). Prostaglandins 1991; 42:71-9.
    • (1991) Prostaglandins , vol.42 , pp. 71-79
    • Cabrol, D.1    Carbonne, B.2    Bienkiewicz, A.3    Dallat, E.4    Alj, A.E.5    Cedard, L.6
  • 43
    • 0026393475 scopus 로고
    • Effects of RU486 on the interstitial collagenase in the process of cervical ripening in the pregnant rat
    • 43. Ikuta Y, Matsuura K, Okamura H, Oyamada I, Usuku G. Effects of RU486 on the interstitial collagenase in the process of cervical ripening in the pregnant rat. Endocrinol Jpn 1991;38:491-6.
    • (1991) Endocrinol Jpn , vol.38 , pp. 491-496
    • Ikuta, Y.1    Matsuura, K.2    Okamura, H.3    Oyamada, I.4    Usuku, G.5
  • 44
    • 0024501410 scopus 로고
    • Progesterone antagonist (RU486) for cervical dilation, labor induction, and delivery in monkeys: Effectiveness in combination with oxytocin
    • 44. Wolf JP, Sinocich M, Anderson TL, Ulmann A, Baulieu EE, Hodgen GD. Progesterone antagonist (RU486) for cervical dilation, labor induction, and delivery in monkeys: effectiveness in combination with oxytocin. Am J Obstet Gynecol 1989;160:45-7.
    • (1989) Am J Obstet Gynecol , vol.160 , pp. 45-47
    • Wolf, J.P.1    Sinocich, M.2    Anderson, T.L.3    Ulmann, A.4    Baulieu, E.E.5    Hodgen, G.D.6
  • 45
    • 0010662079 scopus 로고
    • Use of antiprogestins after 63 days of amenorrhea
    • Donaldson MS, Dorflinger L, Brown SS, Benet LZ, editors. Washington, DC: National Academy Press
    • 45. Ulmann A, Silvestre L. Use of antiprogestins after 63 days of amenorrhea. In: Donaldson MS, Dorflinger L, Brown SS, Benet LZ, editors. Clinical application of mifepristone (RU486) and other antiprogestins. Washington, DC: National Academy Press, 1993:174-82.
    • (1993) Clinical Application of Mifepristone (RU486) and Other Antiprogestins , pp. 174-182
    • Ulmann, A.1    Silvestre, L.2
  • 47
    • 0025214549 scopus 로고
    • The use of mifepristone (RU486) for cervical preparation in first trimester pregnancy termination by vacuum aspiration
    • 47. World Health Organization. The use of mifepristone (RU486) for cervical preparation in first trimester pregnancy termination by vacuum aspiration. Br J Obstet Gynaecol 1990; 97:260-6.
    • (1990) Br J Obstet Gynaecol , vol.97 , pp. 260-266
  • 48
    • 0023712804 scopus 로고
    • Induced cervical ripening with mifepristone in first trimester abortion. A double-blind randomized biochemical study
    • 48. Radestad A, Christensen NJ, Stromberg L. Induced cervical ripening with mifepristone in first trimester abortion. A double-blind randomized biochemical study. Contraception 1988; 38:301-12.
    • (1988) Contraception , vol.38 , pp. 301-312
    • Radestad, A.1    Christensen, N.J.2    Stromberg, L.3
  • 49
    • 0025303095 scopus 로고
    • Effect of mifepristone on dilatation of the pregnant and non-pregnant cervix
    • 49. Gupta JK, Johnson N. Effect of mifepristone on dilatation of the pregnant and non-pregnant cervix. Lancet 1990;335: 1238-40.
    • (1990) Lancet , vol.335 , pp. 1238-1240
    • Gupta, J.K.1    Johnson, N.2
  • 50
    • 0026070110 scopus 로고
    • Preoperative cervical preparation before first trimester vacuum aspiration: A randomized controlled comparison between gemeprost and mifepristone (RU486)
    • 50. Henshaw RC, Templeton AA. Preoperative cervical preparation before first trimester vacuum aspiration: a randomized controlled comparison between gemeprost and mifepristone (RU486). Br J Obstet Gynaecol 1991;98:1025-30.
    • (1991) Br J Obstet Gynaecol , vol.98 , pp. 1025-1030
    • Henshaw, R.C.1    Templeton, A.A.2
  • 51
    • 0026739937 scopus 로고
    • Labour induction in women at term with mifepristone (RU486): A double-blind, randomized, placebo-controlled study
    • 51. Frydman R, Lelaidier C, Baton-Saint-Mieux C, Fernandez H, Vial M, Bourget P. Labour induction in women at term with mifepristone (RU486): a double-blind, randomized, placebo-controlled study. Obstet Gynecol 1992;80:972-5.
    • (1992) Obstet Gynecol , vol.80 , pp. 972-975
    • Frydman, R.1    Lelaidier, C.2    Baton-Saint-Mieux, C.3    Fernandez, H.4    Vial, M.5    Bourget, P.6
  • 52
    • 0024825805 scopus 로고
    • Antiprogestational steroids: A new dimension in human fertility regulation
    • 52. Van Look PF, Bygdman M. Antiprogestational steroids: a new dimension in human fertility regulation. Oxf Rev Reprod Biol 1989;11:2-60.
    • (1989) Oxf Rev Reprod Biol , vol.11 , pp. 2-60
    • Van Look, P.F.1    Bygdman, M.2
  • 54
    • 0025916810 scopus 로고
    • Alternative treatments in oral postcoital contraception: Interim results
    • 54. Webb AMC. Alternative treatments in oral postcoital contraception: interim results. Adv Contracept 1991;7:271-9.
    • (1991) Adv Contracept , vol.7 , pp. 271-279
    • Webb, A.M.C.1
  • 55
    • 0026761586 scopus 로고
    • Mifepristone (RU486) compared with high dose estrogen and progestogen for emergency postcoital treatment
    • 55. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU486) compared with high dose estrogen and progestogen for emergency postcoital treatment. N Engl J Med 1992;327:1041-4.
    • (1992) N Engl J Med , vol.327 , pp. 1041-1044
    • Glasier, A.1    Thong, K.J.2    Dewar, M.3    Mackie, M.4    Baird, D.T.5
  • 56
    • 0026641672 scopus 로고
    • Comparison of Yuzpe regimen, danazol and mifepristone (RU486) in oral postcoital contraception
    • 56. Webb AMC, Russell J, Elstein M. Comparison of Yuzpe regimen, danazol and mifepristone (RU486) in oral postcoital contraception. Br Med J 1992;305:927-31.
    • (1992) Br Med J , vol.305 , pp. 927-931
    • Webb, A.M.C.1    Russell, J.2    Elstein, M.3
  • 57
    • 0025924793 scopus 로고
    • Contraception with mifepristone
    • 57. Swahn ML, Gemzell K, Bygdeman M. Contraception with mifepristone [letter]. Lancet 1991;338:942-3.
    • (1991) Lancet , vol.338 , pp. 942-943
    • Swahn, M.L.1    Gemzell, K.2    Bygdeman, M.3
  • 58
    • 0018891467 scopus 로고
    • Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tissue
    • 58. Wilson EA, Yang F, Rees ED. Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tissue. Obstet Gynecol 1980;55:20-4.
    • (1980) Obstet Gynecol , vol.55 , pp. 20-24
    • Wilson, E.A.1    Yang, F.2    Rees, E.D.3
  • 60
    • 0023852079 scopus 로고
    • Effects of antiprogesterone (RU486) on the hypothalamic-hypophyseal-ovarian-endometrial axis during the luteal phase of the menstrual cycle
    • 60. Garzo VG, Liu J, Ulmann A, Baulieu E, Yen SSC. Effects of antiprogesterone (RU486) on the hypothalamic-hypophyseal-ovarian-endometrial axis during the luteal phase of the menstrual cycle. J Clin Endocrinol Metab 1988;66:508-17.
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 508-517
    • Garzo, V.G.1    Liu, J.2    Ulmann, A.3    Baulieu, E.4    Yen, S.S.C.5
  • 61
    • 0023914163 scopus 로고
    • Inhibition of folliculogenesis and ovulation by the antiprogesterone RU486
    • 61. Luukkainen T, Heikinheimo O, Haukkamaa M, Lahteenmaki P. Inhibition of folliculogenesis and ovulation by the antiprogesterone RU486. Fertil Steril 1988;49:961-3.
    • (1988) Fertil Steril , vol.49 , pp. 961-963
    • Luukkainen, T.1    Heikinheimo, O.2    Haukkamaa, M.3    Lahteenmaki, P.4
  • 62
    • 0025610482 scopus 로고
    • Accelerated dissolution of luteal-endometrial integrity by the administration of antagonist of gonadotropin-releasing hormone and progesterone to late-luteal phase women
    • 62. Roseff SJ, Kettel LM, Rivier J, Burger HG, Baulieu E, Yen SSC. Accelerated dissolution of luteal-endometrial integrity by the administration of antagonist of gonadotropin-releasing hormone and progesterone to late-luteal phase women. Fertil Steril 1990;54:805-10.
    • (1990) Fertil Steril , vol.54 , pp. 805-810
    • Roseff, S.J.1    Kettel, L.M.2    Rivier, J.3    Burger, H.G.4    Baulieu, E.5    Yen, S.S.C.6
  • 64
    • 0028266740 scopus 로고
    • RU486: Pharmacology and potential use in the treatment of endometriosis and leiomyomata
    • 64. Murphy AA, Castellano PZ. RU486: pharmacology and potential use in the treatment of endometriosis and leiomyomata. Curr Opin Obstet Gynecol 1994;6:269-76.
    • (1994) Curr Opin Obstet Gynecol , vol.6 , pp. 269-276
    • Murphy, A.A.1    Castellano, P.Z.2
  • 65
    • 0002423848 scopus 로고
    • Use of antiprogestins in the management of endometriosis and leiomyoma
    • Donaldson MS, Dorflinger L, Brown SS, Benet LZ, editors. Washington, DC: National Academy Press
    • 65. Yen SSC. Use of antiprogestins in the management of endometriosis and leiomyoma. In: Donaldson MS, Dorflinger L, Brown SS, Benet LZ, editors. Clinical applications of mifepristone (RU486) and other antiprogestins. Washington, DC: National Academy Press, 1993:189-209.
    • (1993) Clinical Applications of Mifepristone (RU486) and Other Antiprogestins , pp. 189-209
    • Yen, S.S.C.1
  • 66
    • 0024559403 scopus 로고
    • Immunohistochemical analysis of estrogen and progesterone receptors in endometriosis: Comparison with normal endometrium during the menstrual cycle and the effect of medical therapy
    • 66. Lessey BA, Melzger DA, Haney AF, McCarty KS. Immunohistochemical analysis of estrogen and progesterone receptors in endometriosis: comparison with normal endometrium during the menstrual cycle and the effect of medical therapy. Fertil Steril 1989;51:409-15.
    • (1989) Fertil Steril , vol.51 , pp. 409-415
    • Lessey, B.A.1    Melzger, D.A.2    Haney, A.F.3    McCarty, K.S.4
  • 67
    • 0026042518 scopus 로고
    • Endocrine responses to long-term administration of the antiprogesterone RU486 in patient with pelvic endometriosis
    • 67. Kettel LM, Murphy AA, Mortola JF, Liu JH, Ulmann A, Yen SSC. Endocrine responses to long-term administration of the antiprogesterone RU486 in patient with pelvic endometriosis. Fertil Steril 1991;56:402-7.
    • (1991) Fertil Steril , vol.56 , pp. 402-407
    • Kettel, L.M.1    Murphy, A.A.2    Mortola, J.F.3    Liu, J.H.4    Ulmann, A.5    Yen, S.S.C.6
  • 69
    • 0017337359 scopus 로고
    • Cell proliferation in normal human breast ducts, fibroadenomas and other ductal hyperplasias measured by nuclear labelling with tritiated thymidine
    • 69. Meyer JS. Cell proliferation in normal human breast ducts, fibroadenomas and other ductal hyperplasias measured by nuclear labelling with tritiated thymidine. Hum Pathol 1977; 8:67-81.
    • (1977) Hum Pathol , vol.8 , pp. 67-81
    • Meyer, J.S.1
  • 70
    • 0022508303 scopus 로고
    • A correlative morphologic study of human breast and endometrium in the menstrual cycle
    • 70. Longacre TA, Bartow SA. A correlative morphologic study of human breast and endometrium in the menstrual cycle. Am J Surg Pathol 1986;10:382-93.
    • (1986) Am J Surg Pathol , vol.10 , pp. 382-393
    • Longacre, T.A.1    Bartow, S.A.2
  • 71
    • 0029005302 scopus 로고
    • Antiprogestins inhibit growth and stimulate differentiation in the normal mammary gland
    • 71. Li M, Spitzer E, Zschiesche W, Binas B, Parcczyk K, Gross R. Antiprogestins inhibit growth and stimulate differentiation in the normal mammary gland. J Cell Physiol 1995; 164:1-8.
    • (1995) J Cell Physiol , vol.164 , pp. 1-8
    • Li, M.1    Spitzer, E.2    Zschiesche, W.3    Binas, B.4    Parcczyk, K.5    Gross, R.6
  • 72
    • 0003070132 scopus 로고
    • Antiprogestins and the treatment of breast cancer
    • Donaldson MS, Dorflinger L, Benet LZ, editors. Washington, DC: National Academy Press
    • 72. Horowitz KB. Antiprogestins and the treatment of breast cancer. In: Donaldson MS, Dorflinger L, Benet LZ, editors. Clinical applications of mifepristone (RU486) and other antiprogestins. Washington, DC: National Academy Press, 1993: 210-28.
    • (1993) Clinical Applications of Mifepristone (RU486) and Other Antiprogestins , pp. 210-228
    • Horowitz, K.B.1
  • 74
    • 0024822416 scopus 로고
    • Antitumor activity of antiprogestins ZK98.299 and RU38.486 in hormone dependent rat and mouse mammary tumors: Mechanistic studies
    • 74. Michno H, Schneider MR, Nishino Y, El Etreby FM. Antitumor activity of antiprogestins ZK98.299 and RU38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies. Breast Cancer Res Treat 1989;14:275-88.
    • (1989) Breast Cancer Res Treat , vol.14 , pp. 275-288
    • Michno, H.1    Schneider, M.R.2    Nishino, Y.3    El Etreby, F.M.4
  • 76
    • 0028301213 scopus 로고
    • Role of progestational therapy for meningiomas
    • 76. Grunberg SM. Role of progestational therapy for meningiomas. Hum Reprod 1994;9(Suppl):202-7.
    • (1994) Hum Reprod , vol.9 , Issue.SUPPL. , pp. 202-207
    • Grunberg, S.M.1
  • 77


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.