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Volumn 19, Issue 1, 2008, Pages 37-44

The effects of antibody treatment on regulatory CD4+CD25+ T cells

Author keywords

Antibodies; Immune tolerance; Immunosuppression; Regulatory T cells; Transplantation

Indexed keywords

ALEMTUZUMAB; BASILIXIMAB; CD40 LIGAND MONOCLONAL ANTIBODY; DACLIZUMAB; LYMPHOCYTE ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD 45RB; MONOCLONAL ANTIBODY CD28; MONOCLONAL ANTIBODY CD3; MONOCLONAL ANTIBODY JJ 316; MONOCLONAL ANTIBODY OX 40; OKT 4; RITUXIMAB; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG;

EID: 40849085424     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2007.12.001     Document Type: Review
Times cited : (5)

References (111)
  • 1
    • 20944443148 scopus 로고    scopus 로고
    • Organ transplantation - how much of the promise has been realized?
    • Lechler R.I., Sykes M., Thomson A.W., and Turka L.A. Organ transplantation - how much of the promise has been realized?. Nat Med 11 (2005) 605-613
    • (2005) Nat Med , vol.11 , pp. 605-613
    • Lechler, R.I.1    Sykes, M.2    Thomson, A.W.3    Turka, L.A.4
  • 2
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M. Mixed chimerism and transplant tolerance. Immunity 14 (2001) 417-424
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 3
    • 0037313473 scopus 로고    scopus 로고
    • The complementary roles of deletion and regulation in transplantation tolerance
    • Lechler R.I., Garden O.A., and Turka L.A. The complementary roles of deletion and regulation in transplantation tolerance. Nat Rev Immunol 3 (2003) 147-158
    • (2003) Nat Rev Immunol , vol.3 , pp. 147-158
    • Lechler, R.I.1    Garden, O.A.2    Turka, L.A.3
  • 4
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood K.J., and Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 3 (2003) 199-210
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 5
    • 15244352325 scopus 로고    scopus 로고
    • Tregs and transplantation tolerance
    • Walsh P.T., Taylor D.K., and Turka L.A. Tregs and transplantation tolerance. J Clin Invest 114 (2004) 1398-1403
    • (2004) J Clin Invest , vol.114 , pp. 1398-1403
    • Walsh, P.T.1    Taylor, D.K.2    Turka, L.A.3
  • 6
    • 0142250489 scopus 로고    scopus 로고
    • A novel means of favorably tipping the balance between cytopathic and regulatory T cells
    • Waldmann T.A. A novel means of favorably tipping the balance between cytopathic and regulatory T cells. Immunity 19 (2003) 465-466
    • (2003) Immunity , vol.19 , pp. 465-466
    • Waldmann, T.A.1
  • 7
    • 0031945499 scopus 로고    scopus 로고
    • How do monoclonal antibodies induce tolerance? A role for infectious tolerance?
    • Waldmann H., and Cobbold S. How do monoclonal antibodies induce tolerance? A role for infectious tolerance?. Annu Rev Immunol 16 (1998) 619-644
    • (1998) Annu Rev Immunol , vol.16 , pp. 619-644
    • Waldmann, H.1    Cobbold, S.2
  • 8
    • 0035524290 scopus 로고    scopus 로고
    • Anti-CD45RB monoclonal antibody-mediated transplantation tolerance
    • Luke P.P., O'Brien C.A., Jevnikar A.M., and Zhong R. Anti-CD45RB monoclonal antibody-mediated transplantation tolerance. Curr Mol Med 1 (2001) 533-543
    • (2001) Curr Mol Med , vol.1 , pp. 533-543
    • Luke, P.P.1    O'Brien, C.A.2    Jevnikar, A.M.3    Zhong, R.4
  • 9
    • 0037313086 scopus 로고    scopus 로고
    • CD3-specific antibody-induced active tolerance: from bench to bedside
    • Chatenoud L. CD3-specific antibody-induced active tolerance: from bench to bedside. Nat Rev Immunol 3 (2003) 123-132
    • (2003) Nat Rev Immunol , vol.3 , pp. 123-132
    • Chatenoud, L.1
  • 10
    • 33644829808 scopus 로고    scopus 로고
    • T cell tolerance induced by therapeutic antibodies
    • Cobbold S.P. T cell tolerance induced by therapeutic antibodies. Philos Trans R Soc Lond B Biol Sci 360 (2005) 1695-1705
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 1695-1705
    • Cobbold, S.P.1
  • 11
    • 0141713778 scopus 로고    scopus 로고
    • Antibody-induced transplantation tolerance: the role of dominant regulation
    • Graca L., Le Moine A., Cobbold S.P., and Waldmann H. Antibody-induced transplantation tolerance: the role of dominant regulation. Immunol Res 28 (2003) 181-191
    • (2003) Immunol Res , vol.28 , pp. 181-191
    • Graca, L.1    Le Moine, A.2    Cobbold, S.P.3    Waldmann, H.4
  • 12
    • 22244462396 scopus 로고    scopus 로고
    • Regulatory T cells in immunologic self-tolerance and autoimmune disease
    • Sakaguchi S., and Sakaguchi N. Regulatory T cells in immunologic self-tolerance and autoimmune disease. Int Rev Immunol 24 (2005) 211-226
    • (2005) Int Rev Immunol , vol.24 , pp. 211-226
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 13
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H., O'Garra A., Bigler M., Rouleau M., Antonenko S., de Vries J.E., et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389 (1997) 737-742
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    de Vries, J.E.6
  • 14
    • 33744990181 scopus 로고    scopus 로고
    • Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells
    • Ochi H., Abraham M., Ishikawa H., Frenkel D., Yang K., Basso A.S., et al. Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells. Nat Med 12 (2006) 627-635
    • (2006) Nat Med , vol.12 , pp. 627-635
    • Ochi, H.1    Abraham, M.2    Ishikawa, H.3    Frenkel, D.4    Yang, K.5    Basso, A.S.6
  • 15
    • 0036122891 scopus 로고    scopus 로고
    • Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4
    • Chang C.C., Ciubotariu R., Manavalan J.S., Yuan J., Colovai A.I., Piazza F., et al. Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 3 (2002) 237-243
    • (2002) Nat Immunol , vol.3 , pp. 237-243
    • Chang, C.C.1    Ciubotariu, R.2    Manavalan, J.S.3    Yuan, J.4    Colovai, A.I.5    Piazza, F.6
  • 16
    • 0032834109 scopus 로고    scopus 로고
    • The molecular mechanisms of veto mediated regulation of alloresponsiveness
    • George J.F., and Thomas J.M. The molecular mechanisms of veto mediated regulation of alloresponsiveness. J Mol Med 77 (1999) 519-526
    • (1999) J Mol Med , vol.77 , pp. 519-526
    • George, J.F.1    Thomas, J.M.2
  • 17
    • 0036533422 scopus 로고    scopus 로고
    • Development and selection of NKT cells
    • MacDonald H.R. Development and selection of NKT cells. Curr Opin Immunol 14 (2002) 250-254
    • (2002) Curr Opin Immunol , vol.14 , pp. 250-254
    • MacDonald, H.R.1
  • 18
    • 0033929005 scopus 로고    scopus 로고
    • Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression
    • Zhang Z.X., Yang L., Young K.J., DuTemple B., and Zhang L. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med 6 (2000) 782-789
    • (2000) Nat Med , vol.6 , pp. 782-789
    • Zhang, Z.X.1    Yang, L.2    Young, K.J.3    DuTemple, B.4    Zhang, L.5
  • 19
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: friend or foe in immunity to infection?
    • Mills K.H. Regulatory T cells: friend or foe in immunity to infection?. Nat Rev Immunol 4 (2004) 841-855
    • (2004) Nat Rev Immunol , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 20
    • 1642321113 scopus 로고    scopus 로고
    • Revival of the regulatory T cell: new targets for drug development
    • Sutmuller R.P., Offringa R., and Melief C.J. Revival of the regulatory T cell: new targets for drug development. Drug Discov Today 9 (2004) 310-316
    • (2004) Drug Discov Today , vol.9 , pp. 310-316
    • Sutmuller, R.P.1    Offringa, R.2    Melief, C.J.3
  • 21
    • 0035806276 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
    • Taylor P.A., Noelle R.J., and Blazar B.R. CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 193 (2001) 1311-1318
    • (2001) J Exp Med , vol.193 , pp. 1311-1318
    • Taylor, P.A.1    Noelle, R.J.2    Blazar, B.R.3
  • 22
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P., Ermann J., Edinger M., Fathman C.G., and Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med 196 (2002) 389-399
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 23
    • 0036604283 scopus 로고    scopus 로고
    • Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance
    • Graca L., Thompson S., Lin C.Y., Adams E., Cobbold S.P., and Waldmann H. Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol 168 (2002) 5558-5565
    • (2002) J Immunol , vol.168 , pp. 5558-5565
    • Graca, L.1    Thompson, S.2    Lin, C.Y.3    Adams, E.4    Cobbold, S.P.5    Waldmann, H.6
  • 24
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • Hara M., Kingsley C.I., Niimi M., Read S., Turvey S.E., Bushell A.R., et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 166 (2001) 3789-3796
    • (2001) J Immunol , vol.166 , pp. 3789-3796
    • Hara, M.1    Kingsley, C.I.2    Niimi, M.3    Read, S.4    Turvey, S.E.5    Bushell, A.R.6
  • 25
    • 2142752959 scopus 로고    scopus 로고
    • Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells
    • discussion 127-131, 203-110
    • Roncarolo M.G., Gregori S., and Levings M. Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells. Novartis Found Symp 252 (2003) 115-127 discussion 127-131, 203-110
    • (2003) Novartis Found Symp , vol.252 , pp. 115-127
    • Roncarolo, M.G.1    Gregori, S.2    Levings, M.3
  • 26
    • 0035191131 scopus 로고    scopus 로고
    • The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance
    • Zelenika D., Adams E., Humm S., Lin C.Y., Waldmann H., and Cobbold S.P. The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance. Immunol Rev 182 (2001) 164-179
    • (2001) Immunol Rev , vol.182 , pp. 164-179
    • Zelenika, D.1    Adams, E.2    Humm, S.3    Lin, C.Y.4    Waldmann, H.5    Cobbold, S.P.6
  • 27
    • 34247643786 scopus 로고    scopus 로고
    • The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road
    • Zhang L., and Zhao Y. The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. J Cell Physiol 211 (2007) 590-597
    • (2007) J Cell Physiol , vol.211 , pp. 590-597
    • Zhang, L.1    Zhao, Y.2
  • 28
    • 0036498794 scopus 로고    scopus 로고
    • Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver
    • Watanabe T., Yoshida M., Shirai Y., Yamori M., Yagita H., Itoh T., et al. Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver. J Immunol 168 (2002) 2188-2199
    • (2002) J Immunol , vol.168 , pp. 2188-2199
    • Watanabe, T.1    Yoshida, M.2    Shirai, Y.3    Yamori, M.4    Yagita, H.5    Itoh, T.6
  • 29
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek D.C., Lu L.F., Quezada S.A., Sakaguchi S., and Noelle R.J. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol 174 (2005) 1783-1786
    • (2005) J Immunol , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 30
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C., Mauze S., Leach M.W., Coffman R.L., and Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 190 (1999) 995-1004
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 32
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • Piccirillo C.A., Letterio J.J., Thornton A.M., McHugh R.S., Mamura M., Mizuhara H., et al. CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 196 (2002) 237-246
    • (2002) J Exp Med , vol.196 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5    Mizuhara, H.6
  • 33
    • 0034077559 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
    • Cederbom L., Hall H., and Ivars F. CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 30 (2000) 1538-1543
    • (2000) Eur J Immunol , vol.30 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 34
    • 0035399580 scopus 로고    scopus 로고
    • Oral exposure to alloantigen generates intragraft CD8+ regulatory cells
    • Zhou J., Carr R.I., Liwski R.S., Stadnyk A.W., and Lee T.D. Oral exposure to alloantigen generates intragraft CD8+ regulatory cells. J Immunol 167 (2001) 107-113
    • (2001) J Immunol , vol.167 , pp. 107-113
    • Zhou, J.1    Carr, R.I.2    Liwski, R.S.3    Stadnyk, A.W.4    Lee, T.D.5
  • 35
    • 0032055354 scopus 로고    scopus 로고
    • Induction of Fas (Apo-1, CD95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins
    • Genestier L., Fournel S., Flacher M., Assossou O., Revillard J.P., and Bonnefoy-Berard N. Induction of Fas (Apo-1, CD95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins. Blood 91 (1998) 2360-2368
    • (1998) Blood , vol.91 , pp. 2360-2368
    • Genestier, L.1    Fournel, S.2    Flacher, M.3    Assossou, O.4    Revillard, J.P.5    Bonnefoy-Berard, N.6
  • 36
    • 0032570744 scopus 로고    scopus 로고
    • Determination of an improved sirolimus (rapamycin)-based regimen for induction of allograft tolerance in mice treated with antilymphocyte serum and donor-specific bone marrow
    • Hale D.A., Gottschalk R., Maki T., and Monaco A.P. Determination of an improved sirolimus (rapamycin)-based regimen for induction of allograft tolerance in mice treated with antilymphocyte serum and donor-specific bone marrow. Transplantation 65 (1998) 473-479
    • (1998) Transplantation , vol.65 , pp. 473-479
    • Hale, D.A.1    Gottschalk, R.2    Maki, T.3    Monaco, A.P.4
  • 38
    • 34548570080 scopus 로고    scopus 로고
    • Anti-thymocyte globulin (ATG) prevents autoimmune encephalomyelitis by expanding myelin antigen-specific Foxp3+ regulatory T cells
    • Chung D.T., Korn T., Richard J., Ruzek M., Kohm A.P., Miller S., et al. Anti-thymocyte globulin (ATG) prevents autoimmune encephalomyelitis by expanding myelin antigen-specific Foxp3+ regulatory T cells. Int Immunol 19 (2007) 1003-1010
    • (2007) Int Immunol , vol.19 , pp. 1003-1010
    • Chung, D.T.1    Korn, T.2    Richard, J.3    Ruzek, M.4    Kohm, A.P.5    Miller, S.6
  • 39
    • 33744505629 scopus 로고    scopus 로고
    • Short administration of polyclonal anti-T cell antibody (ALS) in NOD mice with extensive insulitis prevents subsequent development of autoimmune diabetes
    • Ogawa N., Minamimura K., Kodaka T., and Maki T. Short administration of polyclonal anti-T cell antibody (ALS) in NOD mice with extensive insulitis prevents subsequent development of autoimmune diabetes. J Autoimmun 26 (2006) 225-231
    • (2006) J Autoimmun , vol.26 , pp. 225-231
    • Ogawa, N.1    Minamimura, K.2    Kodaka, T.3    Maki, T.4
  • 40
    • 33646057433 scopus 로고    scopus 로고
    • CD4+ regulatory T cells are spared from deletion by antilymphocyte serum, a polyclonal anti-T cell antibody
    • Minamimura K., Gao W., and Maki T. CD4+ regulatory T cells are spared from deletion by antilymphocyte serum, a polyclonal anti-T cell antibody. J Immunol 176 (2006) 4125-4132
    • (2006) J Immunol , vol.176 , pp. 4125-4132
    • Minamimura, K.1    Gao, W.2    Maki, T.3
  • 41
    • 3042737844 scopus 로고    scopus 로고
    • Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4
    • Ogawa N., List J.F., Habener J.F., and Maki T. Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes 53 (2004) 1700-1705
    • (2004) Diabetes , vol.53 , pp. 1700-1705
    • Ogawa, N.1    List, J.F.2    Habener, J.F.3    Maki, T.4
  • 42
    • 33845698625 scopus 로고    scopus 로고
    • The phenotypic characterization of naturally occurring regulatory CD4+CD25+ T cells
    • Yi H., Zhen Y., Jiang L., Zheng J., and Zhao Y. The phenotypic characterization of naturally occurring regulatory CD4+CD25+ T cells. Cell Mol Immunol 3 (2006) 189-195
    • (2006) Cell Mol Immunol , vol.3 , pp. 189-195
    • Yi, H.1    Zhen, Y.2    Jiang, L.3    Zheng, J.4    Zhao, Y.5
  • 44
    • 33746876350 scopus 로고    scopus 로고
    • Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions
    • Luke P.P., Deng J.P., Lian D., O'Connell P.J., Garcia B., Jevnikar A.M., et al. Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions. Am J Transplant 6 (2006) 2023-2034
    • (2006) Am J Transplant , vol.6 , pp. 2023-2034
    • Luke, P.P.1    Deng, J.P.2    Lian, D.3    O'Connell, P.J.4    Garcia, B.5    Jevnikar, A.M.6
  • 45
    • 0041885454 scopus 로고    scopus 로고
    • Alteration in CD45RBhi/CD45RBlo T-cell ratio following CD45RB monoclonal-antibody therapy occurs by selective deletion of CD45RBhi effector cells
    • Luke P.P., Deng J.P., O'Brien C.A., Everest M., Hall A.V., Chakrabarti S., et al. Alteration in CD45RBhi/CD45RBlo T-cell ratio following CD45RB monoclonal-antibody therapy occurs by selective deletion of CD45RBhi effector cells. Transplantation 76 (2003) 400-409
    • (2003) Transplantation , vol.76 , pp. 400-409
    • Luke, P.P.1    Deng, J.P.2    O'Brien, C.A.3    Everest, M.4    Hall, A.V.5    Chakrabarti, S.6
  • 47
    • 32044471628 scopus 로고    scopus 로고
    • Antigen exposure during enhanced CTLA-4 expression promotes allograft tolerance in vivo
    • Salvalaggio P.R., Camirand G., Ariyan C.E., Deng S., Rogozinski L., Basadonna G.P., et al. Antigen exposure during enhanced CTLA-4 expression promotes allograft tolerance in vivo. J Immunol 176 (2006) 2292-2298
    • (2006) J Immunol , vol.176 , pp. 2292-2298
    • Salvalaggio, P.R.1    Camirand, G.2    Ariyan, C.E.3    Deng, S.4    Rogozinski, L.5    Basadonna, G.P.6
  • 48
    • 33644501805 scopus 로고    scopus 로고
    • Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cells
    • Deng S., Moore D.J., Huang X., Mohiuddin M., Lee M.K.t., Velidedeoglu E., et al. Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cells. J Immunol 176 (2006) 2799-2807
    • (2006) J Immunol , vol.176 , pp. 2799-2807
    • Deng, S.1    Moore, D.J.2    Huang, X.3    Mohiuddin, M.4    Lee, M.K.t.5    Velidedeoglu, E.6
  • 49
    • 20944449677 scopus 로고    scopus 로고
    • An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells
    • Gregori S., Mangia P., Bacchetta R., Tresoldi E., Kolbinger F., Traversari C., et al. An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells. J Exp Med 201 (2005) 1293-1305
    • (2005) J Exp Med , vol.201 , pp. 1293-1305
    • Gregori, S.1    Mangia, P.2    Bacchetta, R.3    Tresoldi, E.4    Kolbinger, F.5    Traversari, C.6
  • 50
    • 34548016111 scopus 로고    scopus 로고
    • Enhancement of lymphokine-activated killer cell induction using anti-CD25 and anti-CTLA-4 monoclonal antibodies
    • Okita R., Yamaguchi Y., Emi A., Matsuura K., and Toge T. Enhancement of lymphokine-activated killer cell induction using anti-CD25 and anti-CTLA-4 monoclonal antibodies. Oncol Rep 17 (2007) 1429-1435
    • (2007) Oncol Rep , vol.17 , pp. 1429-1435
    • Okita, R.1    Yamaguchi, Y.2    Emi, A.3    Matsuura, K.4    Toge, T.5
  • 51
    • 0031586439 scopus 로고    scopus 로고
    • Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group
    • Nashan B., Moore R., Amlot P., Schmidt A.G., Abeywickrama K., and Soulillou J.P. Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group. Lancet 350 (1997) 1193-1198
    • (1997) Lancet , vol.350 , pp. 1193-1198
    • Nashan, B.1    Moore, R.2    Amlot, P.3    Schmidt, A.G.4    Abeywickrama, K.5    Soulillou, J.P.6
  • 52
    • 6844236357 scopus 로고    scopus 로고
    • Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group
    • Vincenti F., Kirkman R., Light S., Bumgardner G., Pescovitz M., Halloran P., et al. Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group. N Engl J Med 338 (1998) 161-165
    • (1998) N Engl J Med , vol.338 , pp. 161-165
    • Vincenti, F.1    Kirkman, R.2    Light, S.3    Bumgardner, G.4    Pescovitz, M.5    Halloran, P.6
  • 53
    • 33746879581 scopus 로고    scopus 로고
    • Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"
    • author reply 2037-2038
    • Stephens L.A., and Anderton S.M. Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J Immunol 177 (2006) 2036 author reply 2037-2038
    • (2006) J Immunol , vol.177 , pp. 2036
    • Stephens, L.A.1    Anderton, S.M.2
  • 54
    • 33746879581 scopus 로고    scopus 로고
    • Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"
    • author reply 2037-2038
    • Zelenay S., and Demengeot J. Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J Immunol 177 (2006) 2036-2037 author reply 2037-2038
    • (2006) J Immunol , vol.177 , pp. 2036-2037
    • Zelenay, S.1    Demengeot, J.2
  • 55
    • 20544457031 scopus 로고    scopus 로고
    • The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade
    • Bigenzahn S., Blaha P., Koporc Z., Pree I., Selzer E., Bergmeister H., et al. The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade. Am J Transplant 5 (2005) 1237-1247
    • (2005) Am J Transplant , vol.5 , pp. 1237-1247
    • Bigenzahn, S.1    Blaha, P.2    Koporc, Z.3    Pree, I.4    Selzer, E.5    Bergmeister, H.6
  • 56
    • 3543088545 scopus 로고    scopus 로고
    • Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation
    • Martin P.J., Pei J., Gooley T., Anasetti C., Appelbaum F.R., Deeg J., et al. Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation. Biol Blood Marrow Transplant 10 (2004) 552-560
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 552-560
    • Martin, P.J.1    Pei, J.2    Gooley, T.3    Anasetti, C.4    Appelbaum, F.R.5    Deeg, J.6
  • 57
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller R.P., van Duivenvoorde L.M., van Elsas A., Schumacher T.N., Wildenberg M.E., Allison J.P., et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194 (2001) 823-832
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6
  • 58
    • 3242736641 scopus 로고    scopus 로고
    • Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
    • Jones E., Dahm-Vicker M., Simon A.K., Green A., Powrie F., Cerundolo V., et al. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immun 2 (2002) 1
    • (2002) Cancer Immun , vol.2 , pp. 1
    • Jones, E.1    Dahm-Vicker, M.2    Simon, A.K.3    Green, A.4    Powrie, F.5    Cerundolo, V.6
  • 59
    • 5144228905 scopus 로고    scopus 로고
    • In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer
    • Nagai H., Horikawa T., Hara I., Fukunaga A., Oniki S., Oka M., et al. In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer. Exp Dermatol 13 (2004) 613-620
    • (2004) Exp Dermatol , vol.13 , pp. 613-620
    • Nagai, H.1    Horikawa, T.2    Hara, I.3    Fukunaga, A.4    Oniki, S.5    Oka, M.6
  • 60
    • 33644841622 scopus 로고    scopus 로고
    • Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells
    • Kohm A.P., McMahon J.S., Podojil J.R., Begolka W.S., DeGutes M., Kasprowicz D.J., et al. Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells. J Immunol 176 (2006) 3301-3305
    • (2006) J Immunol , vol.176 , pp. 3301-3305
    • Kohm, A.P.1    McMahon, J.S.2    Podojil, J.R.3    Begolka, W.S.4    DeGutes, M.5    Kasprowicz, D.J.6
  • 61
    • 14644396156 scopus 로고    scopus 로고
    • Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro
    • Game D.S., Hernandez-Fuentes M.P., and Lechler R.I. Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro. Am J Transplant 5 (2005) 454-464
    • (2005) Am J Transplant , vol.5 , pp. 454-464
    • Game, D.S.1    Hernandez-Fuentes, M.P.2    Lechler, R.I.3
  • 62
    • 33845675770 scopus 로고    scopus 로고
    • Following Anti-CD25 Treatment, A Functional CD4+CD25+ Regulatory T-Cell Pool Is Present in Renal Transplant Recipients
    • Kreijveld E., Koenen H.J., Klasen I.S., Hilbrands L.B., and Joosten I. Following Anti-CD25 Treatment, A Functional CD4+CD25+ Regulatory T-Cell Pool Is Present in Renal Transplant Recipients. Am J Transplant 7 (2007) 249-255
    • (2007) Am J Transplant , vol.7 , pp. 249-255
    • Kreijveld, E.1    Koenen, H.J.2    Klasen, I.S.3    Hilbrands, L.B.4    Joosten, I.5
  • 63
    • 27444441270 scopus 로고    scopus 로고
    • Update on rituximab
    • Eisenberg R. Update on rituximab. Ann Rheum Dis 64 Suppl 4 (2005) iv55-iv57
    • (2005) Ann Rheum Dis , vol.64 , Issue.SUPPL. 4
    • Eisenberg, R.1
  • 64
    • 27344452193 scopus 로고    scopus 로고
    • Rituximab anti-B-cell therapy in systemic lupus erythematosus: pointing to the future
    • Sfikakis P.P., Boletis J.N., and Tsokos G.C. Rituximab anti-B-cell therapy in systemic lupus erythematosus: pointing to the future. Curr Opin Rheumatol 17 (2005) 550-557
    • (2005) Curr Opin Rheumatol , vol.17 , pp. 550-557
    • Sfikakis, P.P.1    Boletis, J.N.2    Tsokos, G.C.3
  • 65
    • 28744446703 scopus 로고    scopus 로고
    • Rituximab: a promising therapy in systemic lupus erythematosus
    • Thatayatikom A., and White A.J. Rituximab: a promising therapy in systemic lupus erythematosus. Autoimmun Rev 5 (2006) 18-24
    • (2006) Autoimmun Rev , vol.5 , pp. 18-24
    • Thatayatikom, A.1    White, A.J.2
  • 66
    • 33845869839 scopus 로고    scopus 로고
    • Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE
    • Vallerskog T., Gunnarsson I., Widhe M., Risselada A., Klareskog L., van Vollenhoven R., et al. Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE. Clin Immunol 122 (2007) 62-74
    • (2007) Clin Immunol , vol.122 , pp. 62-74
    • Vallerskog, T.1    Gunnarsson, I.2    Widhe, M.3    Risselada, A.4    Klareskog, L.5    van Vollenhoven, R.6
  • 67
    • 0034584830 scopus 로고    scopus 로고
    • Anti-CD4 monoclonal antibody therapy in human autoimmune diseases
    • Schulze-Koops H., and Lipsky P.E. Anti-CD4 monoclonal antibody therapy in human autoimmune diseases. Curr Dir Autoimmun 2 (2000) 24-49
    • (2000) Curr Dir Autoimmun , vol.2 , pp. 24-49
    • Schulze-Koops, H.1    Lipsky, P.E.2
  • 68
    • 0037385274 scopus 로고    scopus 로고
    • Altered proximal T-cell receptor signalling events in mouse CD4+ T cells in the presence of anti-CD4 monoclonal antibodies: evidence for reduced phosphorylation of Zap-70 and LAT
    • Pullar C.E., Morris P.J., and Wood K.J. Altered proximal T-cell receptor signalling events in mouse CD4+ T cells in the presence of anti-CD4 monoclonal antibodies: evidence for reduced phosphorylation of Zap-70 and LAT. Scand J Immunol 57 (2003) 333-341
    • (2003) Scand J Immunol , vol.57 , pp. 333-341
    • Pullar, C.E.1    Morris, P.J.2    Wood, K.J.3
  • 69
    • 0026806050 scopus 로고
    • Induction of transplantation tolerance in adults using donor antigen and anti-CD4 monoclonal antibody
    • Pearson T.C., Madsen J.C., Larsen C.P., Morris P.J., and Wood K.J. Induction of transplantation tolerance in adults using donor antigen and anti-CD4 monoclonal antibody. Transplantation 54 (1992) 475-483
    • (1992) Transplantation , vol.54 , pp. 475-483
    • Pearson, T.C.1    Madsen, J.C.2    Larsen, C.P.3    Morris, P.J.4    Wood, K.J.5
  • 70
    • 0029893961 scopus 로고    scopus 로고
    • Kinetics of induction of transplantation tolerance with a nondepleting anti-Cd4 monoclonal antibody and donor-specific transfusion before transplantation. A critical period of time is required for development of immunological unresponsiveness
    • Saitovitch D., Bushell A., Mabbs D.W., Morris P.J., and Wood K.J. Kinetics of induction of transplantation tolerance with a nondepleting anti-Cd4 monoclonal antibody and donor-specific transfusion before transplantation. A critical period of time is required for development of immunological unresponsiveness. Transplantation 61 (1996) 1642-1647
    • (1996) Transplantation , vol.61 , pp. 1642-1647
    • Saitovitch, D.1    Bushell, A.2    Mabbs, D.W.3    Morris, P.J.4    Wood, K.J.5
  • 71
    • 0029954498 scopus 로고    scopus 로고
    • Recipient cells expressing single donor MHC locus products can substitute for donor-specific transfusion in the induction of transplantation tolerance when pretreatment is combined with anti-Cd4 monoclonal antibody. Evidence for a vital role of Cd4+ T cells in the induction of tolerance to class I molecules
    • Saitovitch D., Morris P.J., and Wood K.J. Recipient cells expressing single donor MHC locus products can substitute for donor-specific transfusion in the induction of transplantation tolerance when pretreatment is combined with anti-Cd4 monoclonal antibody. Evidence for a vital role of Cd4+ T cells in the induction of tolerance to class I molecules. Transplantation 61 (1996) 1532-1538
    • (1996) Transplantation , vol.61 , pp. 1532-1538
    • Saitovitch, D.1    Morris, P.J.2    Wood, K.J.3
  • 72
    • 0029162602 scopus 로고
    • Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response
    • Bushell A., Morris P.J., and Wood K.J. Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response. Eur J Immunol 25 (1995) 2643-2649
    • (1995) Eur J Immunol , vol.25 , pp. 2643-2649
    • Bushell, A.1    Morris, P.J.2    Wood, K.J.3
  • 73
    • 0036467522 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
    • Kingsley C.I., Karim M., Bushell A.R., and Wood K.J. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 168 (2002) 1080-1086
    • (2002) J Immunol , vol.168 , pp. 1080-1086
    • Kingsley, C.I.1    Karim, M.2    Bushell, A.R.3    Wood, K.J.4
  • 74
    • 1642454708 scopus 로고    scopus 로고
    • Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
    • Karim M., Kingsley C.I., Bushell A.R., Sawitzki B.S., and Wood K.J. Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process. J Immunol 172 (2004) 923-928
    • (2004) J Immunol , vol.172 , pp. 923-928
    • Karim, M.1    Kingsley, C.I.2    Bushell, A.R.3    Sawitzki, B.S.4    Wood, K.J.5
  • 75
    • 0030897222 scopus 로고    scopus 로고
    • Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
    • Osterborg A., Dyer M.J., Bunjes D., Pangalis G.A., Bastion Y., Catovsky D., et al. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol 15 (1997) 1567-1574
    • (1997) J Clin Oncol , vol.15 , pp. 1567-1574
    • Osterborg, A.1    Dyer, M.J.2    Bunjes, D.3    Pangalis, G.A.4    Bastion, Y.5    Catovsky, D.6
  • 76
    • 0036244517 scopus 로고    scopus 로고
    • Cell surface antigen and molecular targeting in the treatment of hematologic malignancies
    • Countouriotis A., Moore T.B., and Sakamoto K.M. Cell surface antigen and molecular targeting in the treatment of hematologic malignancies. Stem Cells 20 (2002) 215-229
    • (2002) Stem Cells , vol.20 , pp. 215-229
    • Countouriotis, A.1    Moore, T.B.2    Sakamoto, K.M.3
  • 78
    • 0027156307 scopus 로고
    • Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy
    • Lockwood C.M., Thiru S., Isaacs J.D., Hale G., and Waldmann H. Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy. Lancet 341 (1993) 1620-1622
    • (1993) Lancet , vol.341 , pp. 1620-1622
    • Lockwood, C.M.1    Thiru, S.2    Isaacs, J.D.3    Hale, G.4    Waldmann, H.5
  • 79
    • 0033949148 scopus 로고    scopus 로고
    • CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells
    • Hale G., Jacobs P., Wood L., Fibbe W.E., Barge R., Novitzky N., et al. CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells. Bone Marrow Transplant 26 (2000) 69-76
    • (2000) Bone Marrow Transplant , vol.26 , pp. 69-76
    • Hale, G.1    Jacobs, P.2    Wood, L.3    Fibbe, W.E.4    Barge, R.5    Novitzky, N.6
  • 80
    • 0033610681 scopus 로고    scopus 로고
    • Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients
    • Calne R., Moffatt S.D., Friend P.J., Jamieson N.V., Bradley J.A., Hale G., et al. Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients. Transplantation 68 (1999) 1613-1616
    • (1999) Transplantation , vol.68 , pp. 1613-1616
    • Calne, R.1    Moffatt, S.D.2    Friend, P.J.3    Jamieson, N.V.4    Bradley, J.A.5    Hale, G.6
  • 81
    • 0038638396 scopus 로고    scopus 로고
    • Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H)
    • Kirk A.D., Hale D.A., Mannon R.B., Kleiner D.E., Hoffmann S.C., Kampen R.L., et al. Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H). Transplantation 76 (2003) 120-129
    • (2003) Transplantation , vol.76 , pp. 120-129
    • Kirk, A.D.1    Hale, D.A.2    Mannon, R.B.3    Kleiner, D.E.4    Hoffmann, S.C.5    Kampen, R.L.6
  • 82
    • 0038805159 scopus 로고    scopus 로고
    • Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study
    • Knechtle S.J., Pirsch J.D., Fechner Jr. J.H., Becker B.N., Friedl A., Colvin R.B., et al. Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study. Am J Transplant 3 (2003) 722-730
    • (2003) Am J Transplant , vol.3 , pp. 722-730
    • Knechtle, S.J.1    Pirsch, J.D.2    Fechner Jr., J.H.3    Becker, B.N.4    Friedl, A.5    Colvin, R.B.6
  • 83
    • 0026741584 scopus 로고
    • The distribution of the CDW52 molecule on blood cells and characterization of its involvement in T cell activation
    • Valentin H., Gelin C., Coulombel L., Zoccola D., Morizet J., and Bernard A. The distribution of the CDW52 molecule on blood cells and characterization of its involvement in T cell activation. Transplantation 54 (1992) 97-104
    • (1992) Transplantation , vol.54 , pp. 97-104
    • Valentin, H.1    Gelin, C.2    Coulombel, L.3    Zoccola, D.4    Morizet, J.5    Bernard, A.6
  • 84
    • 33746836125 scopus 로고    scopus 로고
    • CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells
    • Watanabe T., Masuyama J., Sohma Y., Inazawa H., Horie K., Kojima K., et al. CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells. Clin Immunol 120 (2006) 247-259
    • (2006) Clin Immunol , vol.120 , pp. 247-259
    • Watanabe, T.1    Masuyama, J.2    Sohma, Y.3    Inazawa, H.4    Horie, K.5    Kojima, K.6
  • 85
    • 0036785543 scopus 로고    scopus 로고
    • A novel costimulation pathway via the 4C8 antigen for the induction of CD4+ regulatory T cells
    • Masuyama J., Kaga S., Kano S., and Minota S. A novel costimulation pathway via the 4C8 antigen for the induction of CD4+ regulatory T cells. J Immunol 169 (2002) 3710-3716
    • (2002) J Immunol , vol.169 , pp. 3710-3716
    • Masuyama, J.1    Kaga, S.2    Kano, S.3    Minota, S.4
  • 86
    • 0028882526 scopus 로고
    • Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand
    • Parker D.C., Greiner D.L., Phillips N.E., Appel M.C., Steele A.W., Durie F.H., et al. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proc Natl Acad Sci U S A 92 (1995) 9560-9564
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9560-9564
    • Parker, D.C.1    Greiner, D.L.2    Phillips, N.E.3    Appel, M.C.4    Steele, A.W.5    Durie, F.H.6
  • 87
    • 0004880266 scopus 로고    scopus 로고
    • CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment
    • Zheng X.X., Markees T.G., Hancock W.W., Li Y., Greiner D.L., Li X.C., et al. CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment. J Immunol 162 (1999) 4983-4990
    • (1999) J Immunol , vol.162 , pp. 4983-4990
    • Zheng, X.X.1    Markees, T.G.2    Hancock, W.W.3    Li, Y.4    Greiner, D.L.5    Li, X.C.6
  • 88
    • 15844404353 scopus 로고    scopus 로고
    • Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
    • Larsen C.P., Elwood E.T., Alexander D.Z., Ritchie S.C., Hendrix R., Tucker-Burden C., et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 381 (1996) 434-438
    • (1996) Nature , vol.381 , pp. 434-438
    • Larsen, C.P.1    Elwood, E.T.2    Alexander, D.Z.3    Ritchie, S.C.4    Hendrix, R.5    Tucker-Burden, C.6
  • 89
    • 0032751201 scopus 로고    scopus 로고
    • CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression
    • Honey K., Cobbold S.P., and Waldmann H. CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression. J Immunol 163 (1999) 4805-4810
    • (1999) J Immunol , vol.163 , pp. 4805-4810
    • Honey, K.1    Cobbold, S.P.2    Waldmann, H.3
  • 90
    • 0032996025 scopus 로고    scopus 로고
    • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
    • Kirk A.D., Burkly L.C., Batty D.S., Baumgartner R.E., Berning J.D., Buchanan K., et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat Med 5 (1999) 686-693
    • (1999) Nat Med , vol.5 , pp. 686-693
    • Kirk, A.D.1    Burkly, L.C.2    Batty, D.S.3    Baumgartner, R.E.4    Berning, J.D.5    Buchanan, K.6
  • 91
    • 0033529235 scopus 로고    scopus 로고
    • Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154
    • Kenyon N.S., Chatzipetrou M., Masetti M., Ranuncoli A., Oliveira M., Wagner J.L., et al. Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proc Natl Acad Sci U S A 96 (1999) 8132-8137
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8132-8137
    • Kenyon, N.S.1    Chatzipetrou, M.2    Masetti, M.3    Ranuncoli, A.4    Oliveira, M.5    Wagner, J.L.6
  • 92
    • 0034327171 scopus 로고    scopus 로고
    • Cutting edge: anti-CD154 therapeutic antibodies induce infectious transplantation tolerance
    • Graca L., Honey K., Adams E., Cobbold S.P., and Waldmann H. Cutting edge: anti-CD154 therapeutic antibodies induce infectious transplantation tolerance. J Immunol 165 (2000) 4783-4786
    • (2000) J Immunol , vol.165 , pp. 4783-4786
    • Graca, L.1    Honey, K.2    Adams, E.3    Cobbold, S.P.4    Waldmann, H.5
  • 93
    • 0344984424 scopus 로고    scopus 로고
    • The balance of deletion and regulation in allograft tolerance
    • Zheng X.X., Sanchez-Fueyo A., Domenig C., and Strom T.B. The balance of deletion and regulation in allograft tolerance. Immunol Rev 196 (2003) 75-84
    • (2003) Immunol Rev , vol.196 , pp. 75-84
    • Zheng, X.X.1    Sanchez-Fueyo, A.2    Domenig, C.3    Strom, T.B.4
  • 94
    • 0036498560 scopus 로고    scopus 로고
    • Tracking the immunoregulatory mechanisms active during allograft tolerance
    • Sanchez-Fueyo A., Weber M., Domenig C., Strom T.B., and Zheng X.X. Tracking the immunoregulatory mechanisms active during allograft tolerance. J Immunol 168 (2002) 2274-2281
    • (2002) J Immunol , vol.168 , pp. 2274-2281
    • Sanchez-Fueyo, A.1    Weber, M.2    Domenig, C.3    Strom, T.B.4    Zheng, X.X.5
  • 95
    • 17144393320 scopus 로고    scopus 로고
    • Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
    • Lee I., Wang L., Wells A.D., Dorf M.E., Ozkaynak E., and Hancock W.W. Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med 201 (2005) 1037-1044
    • (2005) J Exp Med , vol.201 , pp. 1037-1044
    • Lee, I.1    Wang, L.2    Wells, A.D.3    Dorf, M.E.4    Ozkaynak, E.5    Hancock, W.W.6
  • 98
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • Herold K.C., Gitelman S.E., Masharani U., Hagopian W., Bisikirska B., Donaldson D., et al. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54 (2005) 1763-1769
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3    Hagopian, W.4    Bisikirska, B.5    Donaldson, D.6
  • 99
    • 0031569177 scopus 로고    scopus 로고
    • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
    • Chatenoud L., Primo J., and Bach J.F. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol 158 (1997) 2947-2954
    • (1997) J Immunol , vol.158 , pp. 2947-2954
    • Chatenoud, L.1    Primo, J.2    Bach, J.F.3
  • 100
    • 0141796312 scopus 로고    scopus 로고
    • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith M., Bluestone J.A., Barriot S., Megret J., Bach J.F., and Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9 (2003) 1202-1208
    • (2003) Nat Med , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Megret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 101
    • 26444515022 scopus 로고    scopus 로고
    • TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs
    • Bisikirska B., Colgan J., Luban J., Bluestone J.A., and Herold K.C. TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. J Clin Invest 115 (2005) 2904-2913
    • (2005) J Clin Invest , vol.115 , pp. 2904-2913
    • Bisikirska, B.1    Colgan, J.2    Luban, J.3    Bluestone, J.A.4    Herold, K.C.5
  • 102
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon B., Lenschow D.J., Rhee L., Ashourian N., Singh B., Sharpe A., et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12 (2000) 431-440
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3    Ashourian, N.4    Singh, B.5    Sharpe, A.6
  • 103
    • 0141920662 scopus 로고    scopus 로고
    • Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells
    • Tang Q., Henriksen K.J., Boden E.K., Tooley A.J., Ye J., Subudhi S.K., et al. Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol 171 (2003) 3348-3352
    • (2003) J Immunol , vol.171 , pp. 3348-3352
    • Tang, Q.1    Henriksen, K.J.2    Boden, E.K.3    Tooley, A.J.4    Ye, J.5    Subudhi, S.K.6
  • 104
    • 33845432336 scopus 로고    scopus 로고
    • Combination of donor-specific blood transfusion with anti-CD28 antibody synergizes to prolong graft survival in rat liver transplantation
    • Urakami H., Ostanin D.V., Hunig T., and Grisham M.B. Combination of donor-specific blood transfusion with anti-CD28 antibody synergizes to prolong graft survival in rat liver transplantation. Transplant Proc 38 (2006) 3244-3246
    • (2006) Transplant Proc , vol.38 , pp. 3244-3246
    • Urakami, H.1    Ostanin, D.V.2    Hunig, T.3    Grisham, M.B.4
  • 106
    • 27444442536 scopus 로고    scopus 로고
    • Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases
    • Beyersdorf N., Hanke T., Kerkau T., and Hunig T. Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases. Ann Rheum Dis 64 Suppl 4 (2005) iv91-iv95
    • (2005) Ann Rheum Dis , vol.64 , Issue.SUPPL. 4
    • Beyersdorf, N.1    Hanke, T.2    Kerkau, T.3    Hunig, T.4
  • 107
    • 0038643708 scopus 로고    scopus 로고
    • Treatment and prevention of experimental autoimmune neuritis with superagonistic CD28-specific monoclonal antibodies
    • Schmidt J., Elflein K., Stienekemeier M., Rodriguez-Palmero M., Schneider C., Toyka K.V., et al. Treatment and prevention of experimental autoimmune neuritis with superagonistic CD28-specific monoclonal antibodies. J Neuroimmunol 140 (2003) 143-152
    • (2003) J Neuroimmunol , vol.140 , pp. 143-152
    • Schmidt, J.1    Elflein, K.2    Stienekemeier, M.3    Rodriguez-Palmero, M.4    Schneider, C.5    Toyka, K.V.6
  • 108
    • 0037352740 scopus 로고    scopus 로고
    • Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist
    • Lin C.H., and Hunig T. Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist. Eur J Immunol 33 (2003) 626-638
    • (2003) Eur J Immunol , vol.33 , pp. 626-638
    • Lin, C.H.1    Hunig, T.2
  • 109
    • 33748505660 scopus 로고    scopus 로고
    • Thrombospondin/CD47 interaction: a pathway to generate regulatory T cells from human CD4+ CD25- T cells in response to inflammation
    • Grimbert P., Bouguermouh S., Baba N., Nakajima T., Allakhverdi Z., Braun D., et al. Thrombospondin/CD47 interaction: a pathway to generate regulatory T cells from human CD4+ CD25- T cells in response to inflammation. J Immunol 177 (2006) 3534-3541
    • (2006) J Immunol , vol.177 , pp. 3534-3541
    • Grimbert, P.1    Bouguermouh, S.2    Baba, N.3    Nakajima, T.4    Allakhverdi, Z.5    Braun, D.6
  • 110
    • 14744285671 scopus 로고    scopus 로고
    • Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR
    • Valzasina B., Guiducci C., Dislich H., Killeen N., Weinberg A.D., and Colombo M.P. Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR. Blood 105 (2005) 2845-2851
    • (2005) Blood , vol.105 , pp. 2845-2851
    • Valzasina, B.1    Guiducci, C.2    Dislich, H.3    Killeen, N.4    Weinberg, A.D.5    Colombo, M.P.6
  • 111
    • 0036061575 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates
    • Adams A.B., Shirasugi N., Durham M.M., Strobert E., Anderson D., Rees P., et al. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes 51 (2002) 265-270
    • (2002) Diabetes , vol.51 , pp. 265-270
    • Adams, A.B.1    Shirasugi, N.2    Durham, M.M.3    Strobert, E.4    Anderson, D.5    Rees, P.6


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