An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells

Journal of Experimental Medicine

Volumn 201, Issue 8, 2005, Pages 1293-1305

  Gregori, Silvia ^a   Mangia, Patrizia ^b   Bacchetta, Rosa ^a   Tresoldi, Eleonora ^a   Kolbinger, Frank ^d   Traversari, Catia ^b   Carballido, Josè M ^e   De Vries, Jan E ^e   Korthäuer, Ulf ^e   Roncarolo, Maria Grazia ^a,c  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b MOLMED S P A   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d NOVARTIS PHARMA AG   (Switzerland)

^e Novartis Institutes for Biomed Res   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RO ANTIGEN; CHIMERIC ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 10; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; RETINOBLASTOMA PROTEIN; TETANUS TOXOID;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DIABETES MELLITUS; EFFECTOR CELL; FEMALE; GRAFT SURVIVAL; INTERFERON PRODUCTION; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; ANTIGENS, CD45; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; GRAFT SURVIVAL; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; MICE, SCID; MICROFILAMENT PROTEINS; PROTEIN-TYROSINE KINASES; TETANUS TOXOID;

EID: 20944449677     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040912     Document Type: Article

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