Imidazolidines as new anti-Trypanosoma cruzi agents: Biological evaluation and structure-activity relationships

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 5, 2008, Pages 2226-2234

  Caterina, M Cristina ^a   Perillo, Isabel A ^a   Boiani, Lucía ^b   Pezaroglo, Horacio ^b   Cerecetto, Hugo ^b   González, Mercedes ^b   Salerno, Alejandra ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Anti Trypanosoma cruzi compounds; Imidazolidines; QSAR

Indexed keywords

1 BENZYL 2,3 DIPHEYLIMIDAZOLIDINE; 1 BENZYL 3 PHENYLIMIDAZOLIDINE; 1,3 DI (3 CHLOROBENZYL) 2 PHENYLIMIDAZOLIDINE; 1,3 DI (3 CHLOROBENZYL)IMIDAZOLIDINE; 1,3 DI (3,4 DICHLOROBENZYL) 2 (2 FURYL)IMIDAZOLIDINE; 1,3 DI (3,4 DICHLOROBENZYL) 2 (3,4 DICHLOROPHENYL)IMIDAZOLIDINE; 1,3 DI (3,4 DICHLOROBENZYL) 2 (4 CHLOROPHENYL)IMIDAZOLIDINE; 1,3 DI (4 CHLOROBENZYL) 2 (3 HYDROXYPHENYL)IMIDAZOLIDINE; 1,3 DI (4 CHLOROBENZYL) 2 (4 NITROPHENYL)IMIDAZOLIDINE; 1,3 DI (4 METHYLBENZYL) 2 (3 CHLOROPHENYL)IMIDAZOLIDINE; 1,3 DI (4 METHYLBENZYL) 2 (4 CHLOROPHENYL)IMIDAZOLIDINE; 1,3 DI (4 METHYLBENZYL) 2 PHENYLIMIDAZOLIDINE; BISIMIDAZOLIDINE DERIVATIVE; IMIDAZOLINE DERIVATIVE; NIFURTIMOX; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; EPIMASTIGOTE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

ANIMALS; ETHYLENES; IMIDAZOLIDINES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 40749087168     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.077     Document Type: Article

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