The -250G/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 18, Issue 3, 2008, Pages 173-181

  Jimenez Gomez Y ^a   Perez Jimenez F ^a   Marin C ^a   Gomez P ^a   Moreno, R ^a   Delgado, J ^a   Perez Martinez P ^a   Gomez M J ^a   Lopez Miranda J ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

250G A polymorphism; Postprandial lipemia; Retinyl palmitate; Triacylglycerol rich lipoproteins; Triacylglycerols

Indexed keywords

EID: 40649127478     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2006.11.002     Document Type: Article

References (48)

1. G. Olivecrona T. Olivecrona Triglyceride lipases and atherosclerosis Curr Opin Lipidol 6 1995 291 305
2. A. Bensadoun D.E. Berryman Genetics and molecular biology of hepatic lipase Curr Opin Lipidol 7 1996 77 81
3. J.C. Cohen G.L. Vega S.M. Grundy Hepatic lipase: new insights from genetic and metabolic studies Curr Opin Lipidol 10 1999 259 267
4. T. Demant L.A. Carlson L. Holmquist F. Karpe P. Nilsson-Ehle C.J. Packard Lipoprotein metabolism in hepatic lipase deficiency: Studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein J Lipid Res 29 1988 1603 1611
5. A. Krapp S. Ahle S. Kersting Y. Hua K. Kneser M. Nielsen Hepatic lipase mediates the uptake of chylomicrons and beta-VLDL into cells via the LDL receptor-related protein (LRP) J Lipid Res 37 1996 926 936
6. M. Komaromy S. Azhar A.D. Cooper Chinese hamster ovary cells expressing a cell surface-anchored form of hepatic lipase. Characterization of low density lipoprotein and chylomicron remnant uptake and selective uptake of high density lipoprotein-cholesteryl ester J Biol Chem 271 1996 16906 16914
7. S. Santamarina-Fojo C. Haudenschild M. Amar The role of hepatic lipase in lipoprotein metabolism and atherosclerosis Curr Opin Lipidol 9 1998 211 219
8. A. Barrans X. Collet R. Barbaras B. Jarpard J. Manent C. Vieu Hepatic lipase induces the formation of pre-beta 1 high density lipoprotein (HDL) from triacylglycerol-rich HDL2: a study comparing liver perfusion to in vitro incubation with lipases J Biol Chem 269 1994 11572 11577
9. M.A. Clay H.H. Newnham T.M. Forte P.I. Barter Cholesteryl ester transfer protein and hepatic lipase activity promote shedding of apo A-I from HDL and subsequent formation of discoidal HDL Biochim Biophys Acta 1124 1992 52 58
10. A. Zambon M.A. Austin B.G. Brown J.E. Hokanson J.D. Brunzell Effect of hepatic lipase on LDL in normal men and those with coronary artery disease Arterioscler Thromb 13 1993 147 153
11. J.P. Despres M. Ferland S. Moorjani A. Nadeau A. Tremblay P.J. Lupien Role of hepatic-triglyceride lipase activity in the association between intra-abdominal fat and plasma HDL cholesterol in obese women Arteriosclerosis 9 1989 485 492
12. G.L. Vega L.T. Clark A. Tang S. Marcovina S.M. Grundy J.C. Cohen Hepatic lipase activity is lower in African American men than in white American men: effects of 5′ flanking polymorphism in the hepatic lipase gene (LIPC) J Lipid Res 39 1998 228 232
13. A. Zambon S.S. Deeb J.E. Hokanson B.G. Brown J.D. Brunzell Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol Arterioscler Thromb Vasc Biol 18 1998 1723 1729
14. P.L. Colvin Jr. B.J. Auerbach L.D. Case W.R. Hazzard D. Applebaum-Bowden A dose-response relationship between sex hormone-induced change in hepatic triglyceride lipase and high-density lipoprotein cholesterol in postmenopausal women Metabolism 40 1991 1052 1056
15. J.K. Huttunen C. Ehnholm M. Kekki E.A. Nikkila Post heparin plasma lipoprotein lipase and hepatic lipase in normal subjects and patients with hypertriglyceridemia: correlations to sex, age, and various parameters of triglyceride metabolism Clin Sci Mol Med 50 1976 249 260
16. P.T. Willians R.M. Krauss Associations of age, adiposity, menopause and alcohol intake with low-density lipoprotein subclasses Arterioscler Thromb Vasc Biol 17 1997 1082 1090
17. R. Guerra J. Wang S.M. Grundy J.C. Cohen A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol Proc Natl Acad Sci USA 94 1997 4532 4537
18. E. Tahvanainen M. Syvänne M. Frick S. Murtomäki-Repo M. Antikainen Y. Kesäniemi Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene: the LOCAT study Investigators J Clin Invest 101 1998 956 960
19. H. Jansen G. Chu C. Ehnholm J. Dallongeville V. Nicaud P. Talmud The T allele of the hepatic lipase promoter variant C-480T is associated with increased fasting lipids and HDL and increased preprandial and postprandial LPCIII:B: European Atherosclerosis Research Study (EARS) II Arterioscl Thromb Vasc Biol 19 1999 303 308
20. H. Jansen A. Verhoeven L. Weeks J. Kastelein D. Halley A. van den Ouweland Common C-to-T substitution at position −480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients Arterioscler Thromb Vasc Biol. 17 1997 2837 2842
21. F. Sultan D. Lagrange H. Jansen S. Griglio Inhibition of hepatic lipase activity impairs chylomicron remnant removal in rats Biochim Biophys Acta 1042 1990 150 152
22. S. Shafi S.E. Brady A. Bensadoun R.J. Havel Role of hepatic lipase in the uptake and processing of chylomicrons remnants in rat liver J Lipid Res 35 1994 709 720
23. P. Gomez J. Lopez-Miranda C. Marin C. Bellido J.A. Moreno R. Moreno Influence of the −514C/T polymorphism in the promoter of the hepatic lipase gene on postprandial lipoprotein metabolism Atherosclerosis 174 2004 73 79 10.1016/j.atherosclerosis.2003.12.038
24. E. Boerwinkle S. Brown A.R. Sharrett G. Heiss W. Patsch Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations Am J Hum Genet 54 1994 341 360
25. G. Bucolo H. David Quantitative determination of serum triglycerides by use of enzymes Clin Chem 19 1973 476 482
26. C.C. Allain L.S. Poon C.S.G. Chang W. Richmond P.C. Fu Enzymatic determination of total serum cholesterol Clin Chem 20 1974 470 475
27. P. Riepponen J. Marniemi T. Rautaoja Immunoturbidimetric determination of apolipoproteins A-1 and B in serum Scan J Clin Lab Invest 47 1987 739 744
28. G.R. Warnick J.M. Benderson J.J. Albers Dextran sulfate-Mg precipitation procedure for quantitation of high density lipoprotein cholesterol Clin Chem 28 1982 1379 1388
29. G. Ruotolo H. Zhang V. Bentsianow N.-A. Le Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia J Lipid Res 33 1992 1541 1549
30. M.G.M. De Ruyter A.P. De Leeheer Simultaneous determination of retinal and retinyl esters in serum or plasma by reversed-phase high performance liquid chromatography Clin Chem 24 1978 1920 1923
31. F. Karpe A. Hamsten Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE J Lipid Res 35 1994 1311 1317
32. Y.L. Ko L.A. Hsu K.H. Hsu Y.H. Ko Y.S. Lee The interactive effects of hepatic lipase gene promoter polymorphisms with sex and obesity on high-density-lipoprotein cholesterol levels in Taiwanese-Chinese Atherosclerosis 172 2004 135 142 10.1016/j.atherosclerosis.2003.09.013
33. W.C. Breckenridge J.A. Little P. Alaupovic C.S. Wang A. Kuksis G. Kakis Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase Atherosclerosis 45 1982 161 179
34. L.A. Carlson L. Holmquist P. Nilsson-Ehle Deficiency of hepatic lipase activity in post-heparin plasma in familial hyper-β-triglyceridemia Acta Med Scand 219 1986 435 447
35. R.A. Vogel M.C. Corretti G.D. Plonick Effect of a single high-fat meal on endothelial function in healthy subjects Am J Cardiol 79 1997 350 354 10.1016/s0002-9149(96)00760-6
36. H.M. Roche M.J. Gibney The impact of post-prandial lipemia in accelerating atherothrombosis J Cardiovasc Risk 7 2000 317 324
37. J. Lopez-Miranda J.M. Ordovas M.A. Ostos C. Marin S. Jansen J. Salas Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein B gene locus Arterioscler Thromb Vasc Biol 17 1997 1765 1773
38. M.A. Ostos J. Lopez-Miranda J.M. Ordovas C. Marin A. Blanco P. Castro Dietary fat clearance is modulated by genetic variation in apolipoprotein A-IV gene locus J Lipid Res 39 1998 2493 2500
39. C. Marin J. Lopez-Miranda P. Gomez E. Paz P. Perez-Martinez F. Fuentes Effects of the human apolipoprotein A-I promoter G-A mutation on postprandial lipoprotein metabolism Am J Clin Nutr 76 2002 319 325
40. J.S. Cohn Postprandial lipemia: emerging evidence for atherogenicity of remnant lipoproteins Can J Cardiol 14 1998 18B 27B
41. F. Karpe Postprandial lipoprotein metabolism and atherosclerosis J Intern Med 246 1999 341 355
42. H.N. Hodis Triglyceride-rich lipoprotein remnant particles and risk of atherosclerosis Circulation 99 1999 2852 2854
43. K. Kugiyama H. Doi K. Takazoe H. Kawano H. Soejima Y. Mizuno Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease Circulation 99 1999 2858 2860
44. S. Chang J. Borensztajn Uptake of chylomicron remnants and hepatic lipase treated chylomicrons by a non-transformed murine hepatocyte cell line in culture Biochim Biophys Acta 1256 1995 81 87
45. W.C. Breckenridge J.A. Little P. Alauporic C.S. Wang A. Kuksis G. Kakis Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase Atherosclerosis 45 1982 161 179
46. Z.S. Ji H.L. Dichek R.D. Miranda R.W. Mahley Heparan sulfate proteoglycans participate in hepatic lipase and apolipoprotein E-mediated binding and uptake of plasma lipoproteins, including high density lipoproteins J Biol Chem 272 1997 31285 31295
47. M.W. Huff D.B. Miller B.M. Wolfe P.W. Connelly C.G. Sawyez Uptake of hypertriglyceridemic very low density lipoproteins and their remnants by HEPG2 cells: the role of lipoprotein lipase, hepatic triglyceride lipase, and cell surface proteoglycans J Lipid Res 38 1997 1318 1333
48. D.L. Ebert R.J. Warren P.J. Barter A. Mitchell Infusion of atherogenic lipoprotein particles increases hepatic lipase activity in the rabbit J Lipid Res 34 1993 89 94