The interactive effects of hepatic lipase gene promoter polymorphisms with sex and obesity on high-density-lipoprotein cholesterol levels in Taiwanese-Chinese

Atherosclerosis

Volumn 172, Issue 1, 2004, Pages 135-142

  Ko, Yu Lin ^a   Hsu, Lung An ^a   Hsu, Kuang Hung ^b   Ko, Yu Hsien ^a   Lee, Ying Shiung ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Genetic polymorphisms; Hepatic lipase; High density lipoprotein cholesterol; Obesity; Taiwanese Chinese

Indexed keywords

AGAROSE; CARRIER PROTEIN; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER TRIACYLGLYCEROL LIPASE; RESTRICTION ENDONUCLEASE; TAQ POLYMERASE; TRIACYLGLYCEROL;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; BLOOD SAMPLING; BODY MASS; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DATA ANALYSIS; DNA EXTRACTION; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OBESITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEX DIFFERENCE; TAIWAN; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0347985753     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2003.09.013     Document Type: Article

References (39)

1. Cohen J.C., Vega G.L., Grundy S.M. Hepatic lipase: new insights from genetic and metabolic studies. Curr. Opin. Lipidol. 10:1999;259-267.
2. Thuren T. Hepatic lipase and HDL metabolism. Curr. Opin. Lipidol. 11:2000;277-283.
3. Rao S.N., Cortese C., Miller N.E., Levy Y., Lewis B. Effects of heparin infusion on plasma lipoproteins in subjects with lipoprotein lipase deficiency. Evidence for a role of hepatic endothelial lipase in the metabolism of high-density lipoprotein subfractions in man. FEBS Lett. 150:1982;255-259.
4. Bamberger M., Lund-Katz S., Phillips M.C., Rothblat G.H. Mechanism of the hepatic lipase induced accumulation of high-density lipoprotein cholesterol by cells in culture. Biochemistry. 24:1985;3693-3701.
5. Johnson W.J., Bamberger M.J., Latta R.A., Rapp P.E., Phillips M.C., Rothblat G.H. The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein. J. Biol. Chem. 261:1986;5766-5776.
6. Sparkes R.S., Zollman S., Klisak I., Kirchgessner T.G., Komaromy M.C., Mohandas T.et al. Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21. Genomics. 1:1987;138-144.
7. Stahnke G., Sprengel R., Augustin J., Will H. Human hepatic triglyceride lipase: cDNA cloning. Differentiation. 35:1987;45-52.
8. Cai S.J., Wong D.M., Chen S.H., Chan L. Structure of the human hepatic triglyceride lipase gene. Biochemistry. 28:1989;8966-8971.
9. Ameis D., Stahnke G., Kobayashi J., McLean J., Lee G., Buscher M.et al. Isolation and characterization of the human hepatic lipase gene. J. Biol. Chem. 265:1990;6552-6555.
10. Datta S., Luo C.C., Li W.H., VanTuinen P., Ledbetter D.H., Brown M.A.et al. Human hepatic lipase. Cloned cDNA sequence, restriction fragment length polymorphisms, chromosomal localization, and evolutionary relationships with lipoprotein lipase and pancreatic lipase. J. Biol. Chem. 263:1988;1107-1110.
11. Kuusi T., Ehnholm C., Viikari J., Harkonen R., Vartiainen E., Puska P.et al. Postheparin plasma lipoprotein and hepatic lipase are determinants of hypo- and hyperalphalipoproteinemia. J. Lipid Res. 30:1989;1117-1126.
12. Vega G.L., Clark L.T., Tang A., Marcovina S., Grundy S.M., Cohen J.C. Hepatic lipase activity is lower in African American men than in white American men: effects of 5′ flanking polymorphism in the hepatic lipase gene (LIPC). J. Lipid Res. 39:1998;228-232.
13. Despres J.P., Couillard C., Gagnon J., Bergeron J., Leon A.S., Rao D.C. et al. Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women: the health, risk factors, exercise training, and genetics (HERITAGE) family study. Arterioscler Thromb. Vasc. Biol. 20:2000;1932-1938.
14. Mahley R.W., Pepin J., Palaoglu K.E., Malloy M.J., Kane J.P., Bersot T.P. Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. J. Lipid Res. 41:2000;1290-1301.
15. Tahvanainen E., Syvanne M., Frick M.H., Murtomaki-Repo S., Antikainen M., Kesaniemi Y.A.et al. Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT study invsestigators. J. Clin. Invest. 101:1998;956-960.
16. Jansen H., Verhoeven A.J., Weeks L., Kastelein J.J., Halley D.J., van den Ouweland A.et al. Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients. Arterioscler. Thromb. Vasc. Biol. 17:1997;2837-2842.
17. Cohen J.C., Wang Z., Grundy S.M., Stoesz M.R., Guerra R. Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels. J. Clin. Invest. 94:1994;2377-2384.
18. Couture P., Otvos J.D., Cupples L.A., Lahoz C., Wilson P.W., Schaefer E.J.et al. Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: the Framingham offspring study. Arterioscler. Thromb. Vasc. Biol. 20:2000;815-822.
19. Guerra R., Wang J., Grundy S.M., Cohen J.C. A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol. Proc. Natl. Acad. Sci. U.S.A. 94:1997;4532-4537.
20. Murtomäki S., Tahvanainen E., Antikainen M., Tiret L., Nicaud V., Jansen H.et al. Hepatic lipase gene polymorphisms influence plasma HDL levels. Results from Finnish EARS participants. European Atherosclerosis Research Study. Arterioscler. Thromb. Vasc. Biol. 17:1997;1879-1884.
21. Zambon A., Deeb S.S., Hokanson J.E., Brown B.G., Brunzell J.D. Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol. Arterioscler. Thromb. Vasc. Biol. 18:1998;1723-1729.
22. Hegele R.A., Harris S.B., Brunt J.H., Young T.K., Hanley A.J., Zinman B.et al. Absence of association between genetic variation in the LIPC gene promoter and plasma lipoproteins in three Canadian populations. Atherosclerosis. 146:1999;153-160.
23. Shohet R.V., Vega G.L., Anwar A., Cigarroa J.E., Grundy S.M., Cohen J.C. Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations. Arterioscler. Thromb. Vasc. Biol. 19:1999;1975-1978.
24. Hong S.H., Song J., Kim J.Q. Genetic variations of the hepatic lipase gene in Korean patients with coronary artery disease. Clin. Biochem. 33:2000;291-296.
25. Hsu L.A., Ko Y.L., Hsu K.H., Ko Y.H., Lee Y.S. Genetic variations in the cholesteryl ester transfer protein gene and high density lipoprotein cholesterol levels in Taiwanese-Chinese. Hum. Genet. 110:2002;57-63.
26. Povey S, Lovering R, Bruford E, Wright M, Lush M, Wain H. The HUGO Gene Nomenclature Committee (HGNC). Hum Genet (2001), DOI 10.1007/s00439-001-0615-0.
27. Thompson E.A., Deeb S., Walker D., Motulsky A.G. The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am. J. Hum. Genet. 42:1988;113-124.
28. Fan D.Z., Liu B.W. Polymorphism of HL +1075C but not -480T. Atherosclerosis. 161:2002;417-424.
29. Inazu A., Nishimura Y., Terada Y., Mabuchi H. Effects of hepatic lipase gene promoter nucleotide variations on serum HDL cholesterol concentration in the general Japanese population. J. Hum. Genet. 46:2001;172-177.
30. Talmud P.J., Berglund L., Hawe E.M., Waterworth D.M., Isasi C.R., Deckelbaum R.E.et al. Age-related effects of genetic variation on lipid levels: the Columbia University BioMarkers study. Pediatrics. 108:2001;E50.
31. Dugi K.A., Brandauer K., Schmidt N., Nau B., Schneider J.G., Mentz S.et al. Low hepatic lipase activity is a novel risk factor for coronary artery disease. Circulation. 104:2001;3057-3062.
32. Rundek T., Elkind M.S., Pittman J., Boden-Albala B., Martin S., Humphries S.E.et al. Carotid intimal-media thickness is associated with allelic variants of stromelysin-1, interleukin-6 and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study. Stroke. 33:2002;1420-1423.
33. Talmud P.J., Ye S., Humphries S.E. Polymorphism in the promoter region of the apoplipoprotein AI gene levels: the European Atherosclerosis Research Study. Genet. Epidemiol. 11:1994;265-280.
34. Minnich A., DeLangavant G., Lavigne J., Roederer G., Lussier-Cacan S., Davignon J. G→A substitution at position -75 of the apolipoprotein A-I gene promoter. Evidence against a direct effect on HDL cholesterol levels. Arterioscler. Thromb. Vasc. Biol. 15:1995;1740-1745.
35. Kark J.D., Sinnreich R., Leitersdorf E., Friedlander Y., Shpitzen S., Luc G. Taq1B CETP polymorphism, plasma CETP, lipoproteins, apolipoproteins and sex differences in a Jewish population sample characterized by low HDL-cholesterol. Atherosclerosis. 151:2000;509-518.
36. Allayee H., Dominguez K.M., Aouizerat B.E., Krauss R.M., Rotter J.I., Lu J. Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J. Lipid Res. 41:2000;245-252.
37. Freeman D.J., Griffin B.A., Holmes A.P., Lindsay G.M., Gaffney D., Packard C.J.et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity. Arterioscler. Thromb. 14:1994;336-344.
38. Swarbrick M.M., Chapman C.M., McQuillan B.M., Hung J., Thompson P.L., Beilby J.P. A Pro12Ala polymorphism in the human peroxisome proliferator- activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity. Eur. J. Endocrinol. 144:2001;277-282.
39. Nie L., Wang J., Clark L.T., Tang A., Vega G.L., Grundy S.M.et al. Body mass index and hepatic lipase gene (LIPC) polymorphism jointly influence postheparin plasma hepatic lipase activity. J. Lipid Res. 39:1998;1127-1130.