Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 640, Issue 1-2, 2008, Pages 107-112

  Taira, Kentaro ^a   Nakamura, Shintaro ^a   Nakano, Khota ^a   Maehara, Daisuke ^a   Okamoto, Keinosuke ^a   Arimoto, Sakae ^a   Loakes, David ^b   Worth Jr , Leroy ^c   Schaaper, Roel M ^c   Seio, Kohji ^d   Sekine, Mitsuo ^d   Negishi, Kazuo ^e   Negishi, Tomoe ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^e OKAYAMA UNIVERSITY   (Japan)

Author keywords

Mismatch repair; Mutation; MutS; O6 ethylguanine; O6 methylguanine

Indexed keywords

6 O ETHYLGUANINE; 6 O METHYLGUANINE; ALKYLATING AGENT; CYTOSINE; GUANINE; GUANINE DERIVATIVE; OLIGONUCLEOTIDE; PROTEIN MUTS; THYMINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BASE PAIRING; BINDING AFFINITY; CORRELATION ANALYSIS; DISSOCIATION CONSTANT; ESCHERICHIA COLI; GENE MUTATION; METHYLATION; MISMATCH REPAIR; MUTAGENESIS; MUTAGENICITY; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY;

PROKARYOTA;

EID: 40649083491     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.12.009     Document Type: Article

References (28)

1. T.M. Marti C. Kunz O. Fleck DNA mismatch repair and mutation avoidance pathways J. Cell. Physiol. 191 2002 28 41
2. P. Modrich Mechanisms in eukaryotic mismatch repair J. Biol. Chem. 281 2006 30305 30309
3. S.-H. Jun T.G. Kim C. Ban DNA mismatch repair system. Classical and fresh roles FEBS J. 273 2006 1609 1619
4. K. Nara F. Nagashima A. Yasui Highly elevated ultraviolet-induced mutation frequency in isolated Chinese hamster cell lines defective in nucleotide excision repair and mismatch repair proteins Cancer Res. 61 2001 50 52
5. W.G. Shanabruch R.P. Rein I. Behlau G.C. Walker Mutagenesis, by methylating and ethylating agents, in mutH , mutL , mutS , and uvrD mutants of Salmonella typhimurium J. Bacteriol. 153 1983 33 44
6. A. Umar M. Koi J.I. Risinger W.E. Glaab K.R. Tindall R.D. Kolodner C.R. Boland J.C. Barrett T.A. Kunkel Correction of hypermutability, N -methyl- N ′-nitro- N -nitroso-guanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6 Cancer Res. 57 1997 3949 3955
7. N. Claij A. van der Wal M. Dekker L. Jansen H. te Riele DNA mismatch repair deficiency stimulates N -ethyl- N -nitrosourea-induced mutagenesis and lymphomagenesis Cancer Res. 63 2003 2062 2066
8. P. Peltomäki Lynch syndrome genes Fam. Cancer 4 2005 227 232
9. L.B. Meira D.L. Cheo A.M. Reis N. Claij D.K. Burns H. te Riele E.C. Friedberg Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer DNA Repair 1 2002 929 934 (Erratum in: DNA Repair 1 (2002) p. 1063)
10. P.D. Hoffman H. Wang C.W. Lawrence S. Iwai F. Hanaoka J.B. Hays Binding of MutS mismatch repair protein to DNA containing UV photoproducts, “mismatched” opposite Watson–Crick and novel nucleotides, in different DNA sequence contexts DNA Repair 4 2005 983 993
11. H. Wang P.D. Hoffman C. Lawrence J.B. Hays Testing excision models for responses of mismatch-repair systems to UV photoproducts in DNA Environ. Mol. Mutagen. 47 2006 296 306
12. 6-methylguanine DNA lesions Carcinogenesis 17 1996 2085 2088
13. I. Babic S.E. Andrew F.R. Jirik MutS interaction with mismatch and alkylated base containing DNA molecules detected by optical biosensor Mutat. Res. 372 1996 87 96
14. K. Negishi D. Maehara S. Nakamura D. Loakes L. Worth Jr. R.M. Schaaper K. Seio M. Sekine T. Negishi Binding specificities of the mismatch binding protein, MutS, to oligonucleotides containing modified bases Nucleic Acids Res. Suppl. 1 2001 221 222
15. K. Negishi D. Loakes R.M. Schaaper Saturation of DNA mismatch repair and error catastrophe by a base analogue in Escherichia coli Genetics 161 2002 1363 1371
16. 6-methyguanine adducts Mol. Cell 22 2006 501 510
17. V. O’Brien R. Brown Signalling cell cycle arrest and cell death through the MMR system Carcinogenesis 27 2006 682 692
18. 6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent Cancer Res. 60 2000 5815 5824
19. C.G. Cupples J.H. Miller A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions Proc. Natl. Acad. Sci. U.S.A. 86 1989 5345 5349
20. K. Seio T. Negishi K. Negishi M. Sekine Mild and facile deprotection for the synthesis of oligodeoxynucleotide incorporating a 6- O -ethyl-deoxyguanosine Lett. Org. Chem. 2 2005 179 183
21. L. Worth Jr. T. Bader J. Yang S. Clark Role of MutS ATPase activity in MutS, l -dependent block of in vitro strand transfer J. Biol. Chem. 273 1998 23176 23182
22. G.J. Jenkins S.H. Doak G.E. Johnson E. Quick E.M. Waters J.M. Parry Do dose response thresholds exist for genotoxic alkylating agents? Mutagenesis 20 2005 389 398
23. A.A. van Zeeland Molecular dosimetry of alkylating agents: quantitative comparison of genetic effects on the basis of DNA adduct formation Mutagenesis 3 1988 179 191
24. F. Drablos E. Feyzi P.A. Aas C.B. Vaagbo B. Kavli M.S. Bratlie J. Pena-Diaz M. Otterlei G. Slupphaug H.E. Krokan Alkylation damage in DNA and RNA-repair mechanisms and medical significance DNA Repair 3 2004 1389 1407
25. M.J. Armstrong S.M. Galloway Mismatch repair provokes chromosome aberrations in hamster cells treated with methylating agents or 6-thioguanine, but not with ethylating agents Mutat. Res. 373 1997 167 178
26. M.D. Wyatt D.L. Pittman Methylating agents and DNA repair responses: methylated bases and sources of strand breaks Chem. Res. Toxicol. 19 2006 1580 1594
27. Y. Goto T. Matsuda K. Ito N.-H. Huh J. Thomale M.F. Rajewsky H. Hayatsu T. Negishi Mutagenicities of N -nitrosodimethylamine and N -nitrosodiethylamine in Drosophila and their relationship to the levels of O -alkyl adducts in DNA Mutat. Res. 425 1999 125 134
28. 4-methylthymine in Escherichia coli using double-stranded and gapped plasmids Carcinogenesis 19 1998 457 461