Checkpoint effects and telomere amplification during DNA re-replication in fission yeast

BMC Molecular Biology

Volumn 8, Issue , 2007, Pages

  Mickle, Katie L ^a   Oliva, Anna ^a   Huberman, Joel A ^b   Leatherwood, Janet ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN 6; CHECKPOINT KINASE 2; CHECKPOINT KINASE RAD3; FUNGAL DNA; CDC18 PROTEIN, S POMBE; CELL CYCLE PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RAD3 PROTEIN, S POMBE; SCHIZOSACCHAROMYCES POMBE PROTEIN;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL MUTANT; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA CONTENT; DNA DAMAGE; DNA MICROARRAY; DNA REPLICATION; DNA SEQUENCE; GENE AMPLIFICATION; GENE DELETION; GENE OVEREXPRESSION; GENETIC VARIABILITY; NONHUMAN; SCHIZOSACCHAROMYCES POMBE; TELOMERE; WILD TYPE; DNA REPLICATION ORIGIN; GENETICS; GENOME; HETEROCHROMATIN; METABOLISM; PHYSIOLOGY; SCHIZOSACCHAROMYCES;

EUKARYOTA; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

CELL CYCLE PROTEINS; DNA REPLICATION; GENOME, FUNGAL; HETEROCHROMATIN; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REPLICATION ORIGIN; S PHASE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; TELOMERE;

EID: 40549124612     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-8-119     Document Type: Article

References (48)

1. Bell SP Dutta A DNA replication in eukaryotic cells Annu Rev Biochem 2002, 71:333-374. 10.1146/annurev.biochem.71.110601.135425 12045100
2. Jallepalli PV Brown GW Muzi-Falconi M Tien D Kelly TJ Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation Genes Dev 1997, 11(21):2767-2779. 316667 9353247 10.1101/gad.11.21.2767
3. Lopez-Girona A Mondesert O Leatherwood J Russell P Negative regulation of Cdc18 DNA replication protein by Cdc2 Mol Biol Cell 1998, 9(1):63-73. 25219 9436991
4. Vas A Mok W Leatherwood J Control of DNA rereplication via Cdc2 phosphorylation sites in the origin recognition complex Mol Cell Biol 2001, 21(17):5767-5777. 87296 11486016 10.1128/MCB.21.17.5767-5777.2001
5. Wuarin J Buck V Nurse P Millar JB Stable association of mitotic cyclin B/ Cdc2 to replication origins prevents endoreduplication Cell 2002, 111(3):419-431. 10.1016/S0092-8674(02)01042-5 12419251
6. Nishitani H Nurse P p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast Cell 1995, 83(3):397-405. 10.1016/0092-8674(95)90117-5 8521469
7. Gopalakrishnan V Simancek P Houchens C Snaith HA Frattini MG Sazer S Kelly TJ Redundant control of rereplication in fission yeast Proc Natl Acad Sci U S A 2001, 98(23):13114-13119. 60833 11606752 10.1073/ pnas.221467598
8. Nishitani H Lygerou Z Nishimoto T Nurse P The Cdt1 protein is required to license DNA for replication in fission yeast Nature 2000, 404(6778):625-628. 10.1038/35007110 10766248
9. Blow JJ Dutta A Preventing re-replication of chromosomal DNA Nat Rev Mol Cell Biol 2005, 6(6):476-486. 10.1038/nrm1663 15928711
10. Muzi Falconi M Brown GW Kelly TJ cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe Proc Natl Acad Sci U S A 1996, 93(4):1566-1570. 39981 8643672 10.1073/pnas.93.4.1566
11. Yanow SK Lygerou Z Nurse P Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication Embo J 2001, 20(17):4648-4656. 125588 11532929 10.1093/emboj/20.17.4648
12. Green BM Morreale RJ Ozaydin B Derisi JL Li JJ Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant Mol Biol Cell 2006, 17(5):2401-2414. 1446083 16481397 10.1091/mbc.E05-11-1043
13. Nguyen VQ Co C Li JJ Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms Nature 2001, 411(6841):1068-1073. 10.1038/ 35082600 11429609
14. Tanny RE MacAlpine DM Blitzblau HG Bell SP Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation Mol Biol Cell 2006, 17(5):2415-2423. 1446079 16525018 10.1091/mbc.E05-11-1037
15. Wilmes GM Archambault V Austin RJ Jacobson MD Bell SP Cross FR Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch Genes Dev 2004, 18(9):981-991. 406289 15105375 10.1101/gad.1202304
16. Archambault V Ikui AE Drapkin BJ Cross FR Disruption of mechanisms that prevent rereplication triggers a DNA damage response Mol Cell Biol 2005, 25(15):6707-6721. 1190345 16024805 10.1128/MCB.25.15.6707-6721.2005
17. Green BM Li JJ Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage Mol Biol Cell 2005, 16(1):421-432. 539184 15537702 10.1091/mbc.E04-09-0833
18. Ikui AE Archambault V Drapkin BJ Campbell V Cross FR Cyclin and cyclin-dependent kinase substrate requirements for preventing rereplication reveal the need for concomitant activation and inhibition Genetics 2007, 175(3):1011-1022. 1840059 17194775 10.1534/ genetics.106.068213
19. Davidson IF Li A Blow JJ Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision Mol Cell 2006, 24(3):433-443. 1819398 17081992 10.1016/j.molcel.2006.09.010
20. Li A Blow JJ Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus Embo J 2005, 24(2):395-404. 545810 15616577 10.1038/sj.emboj.7600520
21. Melixetian M Ballabeni A Masiero L Gasparini P Zamponi R Bartek J Lukas J Helin K Loss of Geminin induces rereplication in the presence of functional p53 J Cell Biol 2004, 165(4):473-482. 10.1083/jcb.200403106 15159417
22. Zhu W Chen Y Dutta A Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint Mol Cell Biol 2004, 24(16):7140-7150. 479725 15282313 10.1128/MCB.24.16.7140-7150.2004
23. Zhu W Dutta A An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication Mol Cell Biol 2006, 26(12):4601-4611. 1489121 16738325 10.1128/MCB.02141-05
24. Jin J Arias EE Chen J Harper JW Walter JC A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1 Mol Cell 2006, 23(5):709-721. 10.1016/j.molcel.2006.08.010 16949367
25. Lovejoy CA Lock K Yenamandra A Cortez D DDB1 maintains genome integrity through regulation of Cdt1 Mol Cell Biol 2006, 26(21):7977-7990. 1636754 16940174 10.1128/MCB.00819-06
26. Machida YJ Dutta A The APC/C inhibitor, Emi1, is essential for prevention of rereplication Genes Dev 2007, 21(2):184-194. 1770901 17234884 10.1101/gad.1495007
27. Vaziri C Saxena S Jeon Y Lee C Murata K Machida Y Wagle N Hwang DS Dutta A A p53-dependent checkpoint pathway prevents rereplication Mol Cell 2003, 11(4):997-1008. 10.1016/S1097-2765(03)00099-6 12718885
28. Foiani M Kumar S Huberman JA Responses to aberrant DNA replication and DNA damage in yeasts. In DNA Replication and Human Disease Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press DePamphilis ML 2006, 335-356.
29. Desdouets C Santocanale C Drury LS Perkins G Foiani M Plevani P Diffley JF Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha Embo J 1998, 17(14):4139-4146. 1170746 9670028 10.1093/emboj/17.14.4139
30. Calvi BR Spradling C The nuclear location and chromatin organization of active chorion amplification origins Chromosoma 2001, 110:159-172. 10.1007/s004120100131 11513291
31. Mickle KL Ramanathan S Rosebrock A Oliva A Chaudari A Yompakdee C Scott D Leatherwood J Huberman JA Checkpoint independence of most DNA replication origins in fission yeast BMC Mol Biol 2007, 8(1):112. 10.1186/1471-2199-8-119 18093330 2235891
32. Kim SM Huberman JA Regulation of replication timing in fission yeast EMBO J 2001, 20(21):6115-6126. 125695 11689451 10.1093/emboj/20.21.6115
33. Kim SM Dubey DD Huberman JA Early-replicating heterochromatin Genes Dev 2003, 17:330-335. 195982 12569122 10.1101/gad.1046203
34. Segurado M de Luis A Antequera F Genome-wide distribution of DNA replication origins at A + T-rich islands in Schizosaccharomyces pombe EMBO Reports 2003, 4(11):1048-1053. 1326378 14566325 10.1038/ sj.embor.7400008
35. Feng W Collingwood D Boeck ME Fox LA Alvino GM Fangman WL Raghuraman MK Brewer BJ Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication Nat Cell Biol 2006, 8(2):148-155. 1414058 16429127 10.1038/ncb1358
36. Heichinger C Penkett CJ Bahler J Nurse P Genome-wide characterization of fission yeast DNA replication origins Embo J 2006, 25(21):5171-5179. 1630417 17053780 10.1038/sj.emboj.7601390
37. Hayashi M Katou Y Itoh T Tazumi M Yamada Y Takahashi T Nakagawa T Shirahige K Masukata H Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast Embo J 2007, 26(5):1327-1339. 10.1038/sj.emboj.7601585 17304213
38. Greenwood E Nishitani H Nurse P Cdc18p can block mitosis by two independent mechanisms J Cell Sci 1998, 111(Pt 20):3101-3108. 9739083
39. Mimura S Seki T Tanaka S Diffley JF Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control Nature 2004, 431(7012):1118-1123. 10.1038/nature03024 15496876
40. Rivin CJ Fangman WL Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae J Cell Biol 1980, 85(1):108-115. 10.1083/jcb.85.1.108 6767729
41. Tanaka K Russell P Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1 Nat Cell Biol 2001, 3:966-972. 10.1038/ ncb1101-966 11715017
42. Ben-Yehoyada M Gautier J Dupré A The DNA damage response during an unperturbed S-phase DNA Repair 2007, 6:914-922. 10.1016/ j.dnarep.2007.02.005 17374515
43. Tourrière H Pasero P Maintenance of fork integrity at damaged DNA and natural pause sites DNA Repair 2007, 6:900-913. 10.1016/ j.dnarep.2007.02.004 17379579
44. Matsuura A Naito T Ishikawa F Genetic control of telomere integrity in Schizosaccharomyces pombe: Rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+) Genetics 1999, 152(4):1501-1512. 1460706 10430579
45. Cam HP Sugiyama T Chen ES Chen X Fitzgerald PC Grewal SIS Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome Nature Genetics 2005, 37:809-819. 10.1038/ng1602 15976807
46. Oliva A Rosebrock A Ferrezuelo F Pyne S Chen H Skiena S Futcher B Leatherwood J The cell cycle-regulated genes of Schizosaccharomyces pombe PLoS Biol 2005, 3(7):e225. 1157095 15966770 10.1371/ journal.pbio.0030225
47. ArrayExpress Home http://www.ebi.ac.uk/arrayexpress/
48. Chromosome Contigs from May 17, 2006 ftp://ftp.sanger.ac.uk/pub2/yeast/ pombe/Chromosome_contigs/OLD/May_17_2006/