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Volumn 175, Issue 3, 2007, Pages 1011-1022

Cyclin and cyclin-dependent kinase substrate requirements for preventing rereplication reveal the need for concomitant activation and inhibition

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN 6; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE CLB6; CYCLINE; MINICHROMOSOME MAINTENANCE PROTEIN 2; MRE11 PROTEIN; PROTEIN RAD1; PROTEIN RAD17; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 34249044772     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.106.068213     Document Type: Article
Times cited : (12)

References (44)
  • 1
    • 0027527033 scopus 로고
    • Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins
    • AMON, A., M. TYERS, B. FUTCHER and K. NASMYTH, 1993 Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell 74: 993-1007.
    • (1993) Cell , vol.74 , pp. 993-1007
    • AMON, A.1    TYERS, M.2    FUTCHER, B.3    NASMYTH, K.4
  • 2
    • 0030886099 scopus 로고    scopus 로고
    • Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
    • APARICIO, O. M., D. M. WEINSTEIN and S. P. BELL, 1997 Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell 91: 59-69.
    • (1997) Cell , vol.91 , pp. 59-69
    • APARICIO, O.M.1    WEINSTEIN, D.M.2    BELL, S.P.3
  • 5
    • 22544470259 scopus 로고    scopus 로고
    • Disruption of mechanisms that prevent rereplication triggers a DNA damage response
    • ARCHAMBAULT, V., A. E. IKUI, B. J. DRAPKIN and F. R. CROSS, 2005b Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol. Cell. Biol. 25: 6707-6721.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 6707-6721
    • ARCHAMBAULT, V.1    IKUI, A.E.2    DRAPKIN, B.J.3    CROSS, F.R.4
  • 6
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • BELL, S. P., and A. DUTTA, 2002 DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71: 333-374.
    • (2002) Annu. Rev. Biochem , vol.71 , pp. 333-374
    • BELL, S.P.1    DUTTA, A.2
  • 7
    • 0025924452 scopus 로고
    • Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
    • BROEK, D., R. BARTLETT, K. CRAWFORD and P. NURSE, 1991 Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature 349: 388-393.
    • (1991) Nature , vol.349 , pp. 388-393
    • BROEK, D.1    BARTLETT, R.2    CRAWFORD, K.3    NURSE, P.4
  • 8
    • 0039596393 scopus 로고    scopus 로고
    • The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae
    • CALZADA, A., M. SANCHEZ, E. SANCHEZ and A. BUENO, 2000 The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae. J. Biol. Chem. 275: 9734-9741.
    • (2000) J. Biol. Chem , vol.275 , pp. 9734-9741
    • CALZADA, A.1    SANCHEZ, M.2    SANCHEZ, E.3    BUENO, A.4
  • 9
    • 0030030623 scopus 로고    scopus 로고
    • An essential role for the Cdc6 protein in forming the prereplicative complexes of budding yeast
    • COCKER, J. H., S. PIATTI, C. SANTOCANALE, K. NASMYTH and J. F. DIFFLEY, 1996 An essential role for the Cdc6 protein in forming the prereplicative complexes of budding yeast. Nature 379: 180-182.
    • (1996) Nature , vol.379 , pp. 180-182
    • COCKER, J.H.1    PIATTI, S.2    SANTOCANALE, C.3    NASMYTH, K.4    DIFFLEY, J.F.5
  • 12
    • 0029410629 scopus 로고
    • S-phase-promoting cyclin-dependent kinases prevent rereplication by inhibiting the transition of replication origins to a pre-replicative state
    • DAHMANN, C., J. F. DIFFLEY and K. A. NASMYTH, 1995 S-phase-promoting cyclin-dependent kinases prevent rereplication by inhibiting the transition of replication origins to a pre-replicative state. Curr. Biol. 5: 1257-1269.
    • (1995) Curr. Biol , vol.5 , pp. 1257-1269
    • DAHMANN, C.1    DIFFLEY, J.F.2    NASMYTH, K.A.3
  • 13
    • 0037117418 scopus 로고    scopus 로고
    • Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae
    • DEVAULT, A., E. A. VALLEN, T. YUAN, S. GREEN, A. BENSIMON et al., 2002 Identification of Tah11/Sid2 as the ortholog of the replication licensing factor Cdt1 in Saccharomyces cerevisiae. Curr. Biol. 12: 689-694.
    • (2002) Curr. Biol , vol.12 , pp. 689-694
    • DEVAULT, A.1    VALLEN, E.A.2    YUAN, T.3    GREEN, S.4    BENSIMON, A.5
  • 14
    • 0028098812 scopus 로고
    • Two steps in the assembly of complexes at yeast replication origins in vivo
    • DIFFLEY, J. F., J. H. COCKER, S. J. DOWELL and A. ROWLEY, 1994 Two steps in the assembly of complexes at yeast replication origins in vivo. Cell 78: 303-316.
    • (1994) Cell , vol.78 , pp. 303-316
    • DIFFLEY, J.F.1    COCKER, J.H.2    DOWELL, S.J.3    ROWLEY, A.4
  • 16
    • 0030868430 scopus 로고    scopus 로고
    • The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
    • DRURY, L. S., G. PERKINS and J. F. DIFFLEY, 1997 The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J. 16: 5966-5976.
    • (1997) EMBO J , vol.16 , pp. 5966-5976
    • DRURY, L.S.1    PERKINS, G.2    DIFFLEY, J.F.3
  • 17
    • 0034624819 scopus 로고    scopus 로고
    • The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle
    • DRURY, L. S., G. PERKINS and J. F. DIFFLEY, 2000 The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle. Curr. Biol. 10: 231-240.
    • (2000) Curr. Biol , vol.10 , pp. 231-240
    • DRURY, L.S.1    PERKINS, G.2    DIFFLEY, J.F.3
  • 18
    • 0032865839 scopus 로고    scopus 로고
    • Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis
    • ELSASSER, S., Y. CHI, P. YANG and J. L. CAMPBELL, 1999 Phosphorylation controls timing of Cdc6p destruction: a biochemical analysis. Mol. Biol. Cell 10: 3263-3277.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3263-3277
    • ELSASSER, S.1    CHI, Y.2    YANG, P.3    CAMPBELL, J.L.4
  • 19
    • 0026699308 scopus 로고
    • CLB5: A novel B cyclin from budding yeast with a role in S phase
    • EPSTEIN, C. B., and F. R. CROSS, 1992 CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 6: 1695-1706.
    • (1992) Genes Dev , vol.6 , pp. 1695-1706
    • EPSTEIN, C.B.1    CROSS, F.R.2
  • 20
    • 11144288986 scopus 로고    scopus 로고
    • Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage
    • GREEN, B. M., and J. J. LI, 2005 Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol. Biol. Cell 16: 421-432.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 421-432
    • GREEN, B.M.1    LI, J.J.2
  • 21
    • 33745763266 scopus 로고    scopus 로고
    • Genomewide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant
    • GREEN, B. M., R. J. MORREALE, B. OZAYDIN, J. L. DERISI and J. J. LI, 2006 Genomewide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol. Biol. Cell 17: 2401-2414.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2401-2414
    • GREEN, B.M.1    MORREALE, R.J.2    OZAYDIN, B.3    DERISI, J.L.4    LI, J.J.5
  • 22
    • 0028059299 scopus 로고
    • Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
    • HAYLES, J., D. FISHER, A. WOOLLARD and P. NURSE, 1994 Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex. Cell 78: 813-822.
    • (1994) Cell , vol.78 , pp. 813-822
    • HAYLES, J.1    FISHER, D.2    WOOLLARD, A.3    NURSE, P.4
  • 23
    • 33644776864 scopus 로고    scopus 로고
    • Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6
    • JACKSON, L. P., S. I. REED and S. B. HAASE, 2006 Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6. Mol. Cell. Biol. 26: 2456-2466.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 2456-2466
    • JACKSON, L.P.1    REED, S.I.2    HAASE, S.B.3
  • 24
    • 0344845078 scopus 로고    scopus 로고
    • Enigmatic variations: Divergent modes of regulating eukaryotic DNA replication
    • KEARSEY, S. E., and S. COTTERILL, 2003 Enigmatic variations: divergent modes of regulating eukaryotic DNA replication. Mol. Cell 12: 1067-1075.
    • (2003) Mol. Cell , vol.12 , pp. 1067-1075
    • KEARSEY, S.E.1    COTTERILL, S.2
  • 25
    • 0033224310 scopus 로고    scopus 로고
    • G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus
    • LABIB, K., J. F. DIFFLEY and S. E. KEARSEY, 1999 G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus. Nat. Cell Biol. 1: 415-422.
    • (1999) Nat. Cell Biol , vol.1 , pp. 415-422
    • LABIB, K.1    DIFFLEY, J.F.2    KEARSEY, S.E.3
  • 26
    • 26244435980 scopus 로고    scopus 로고
    • CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication
    • LIKU, M. E., V. Q. NGUYEN, A. W. ROSALES, K. IRIE and J. J. LI, 2005 CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol. Biol. Cell 16: 5026-5039.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5026-5039
    • LIKU, M.E.1    NGUYEN, V.Q.2    ROSALES, A.W.3    IRIE, K.4    LI, J.J.5
  • 27
    • 14544270984 scopus 로고    scopus 로고
    • Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
    • LOOG, M., and D. O. MORGAN, 2005 Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434: 104-108.
    • (2005) Nature , vol.434 , pp. 104-108
    • LOOG, M.1    MORGAN, D.O.2
  • 29
    • 0037757742 scopus 로고    scopus 로고
    • Regulation of the localization and stability of Cdc6 in living yeast cells
    • LUO, K. Q., S. ELSASSER, D. C. CHANG and J. L. CAMPBELL, 2003 Regulation of the localization and stability of Cdc6 in living yeast cells. Biochem. Biophys. Res. Commun. 306: 851-859.
    • (2003) Biochem. Biophys. Res. Commun , vol.306 , pp. 851-859
    • LUO, K.Q.1    ELSASSER, S.2    CHANG, D.C.3    CAMPBELL, J.L.4
  • 30
    • 0037034048 scopus 로고    scopus 로고
    • S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast
    • MASUMOTO, H., S. MURAMATSU, Y. KAMIMURA and H. ARAKI, 2002 S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast. Nature 415: 651-655.
    • (2002) Nature , vol.415 , pp. 651-655
    • MASUMOTO, H.1    MURAMATSU, S.2    KAMIMURA, Y.3    ARAKI, H.4
  • 31
    • 0027339342 scopus 로고
    • An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae
    • MENDENHALL, M. D., 1993 An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae. Science 259: 216-219.
    • (1993) Science , vol.259 , pp. 216-219
    • MENDENHALL, M.D.1
  • 32
    • 7744234408 scopus 로고    scopus 로고
    • Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control
    • MIMURA, S., T. SEKI, S. TANAKA and J. F. DIFFLEY, 2004 Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control. Nature 431: 1118-1123.
    • (2004) Nature , vol.431 , pp. 1118-1123
    • MIMURA, S.1    SEKI, T.2    TANAKA, S.3    DIFFLEY, J.F.4
  • 33
    • 0034708063 scopus 로고    scopus 로고
    • Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7
    • NGUYEN, V. Q., C. CO, K. IRIE and J. J. LI, 2000 Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7. Curr. Biol. 10: 195-205.
    • (2000) Curr. Biol , vol.10 , pp. 195-205
    • NGUYEN, V.Q.1    CO, C.2    IRIE, K.3    LI, J.J.4
  • 34
    • 0035963372 scopus 로고    scopus 로고
    • Cyclin-dependent kinases prevent DNA rereplication through multiple mechanisms
    • NGUYEN, V. Q., C. CO and J. J. LI, 2001 Cyclin-dependent kinases prevent DNA rereplication through multiple mechanisms. Nature 411: 1068-1073.
    • (2001) Nature , vol.411 , pp. 1068-1073
    • NGUYEN, V.Q.1    CO, C.2    LI, J.J.3
  • 35
    • 0035903652 scopus 로고    scopus 로고
    • Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC
    • SCHWAB, M., M. NEUTZNER, D. MOCKER and W. SEUFERT, 2001 Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC. EMBO J. 20: 5165-5175.
    • (2001) EMBO J , vol.20 , pp. 5165-5175
    • SCHWAB, M.1    NEUTZNER, M.2    MOCKER, D.3    SEUFERT, W.4
  • 36
    • 0027220020 scopus 로고
    • CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae
    • SCHWOB, E., and K. NASMYTH, 1993 CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 7: 1160-1175.
    • (1993) Genes Dev , vol.7 , pp. 1160-1175
    • SCHWOB, E.1    NASMYTH, K.2
  • 37
    • 0028114987 scopus 로고
    • The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae
    • SCHWOB, E., T. BOHM, M. D. MENDENHALL and K. NASMYTH, 1994 The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-244.
    • (1994) Cell , vol.79 , pp. 233-244
    • SCHWOB, E.1    BOHM, T.2    MENDENHALL, M.D.3    NASMYTH, K.4
  • 38
    • 0036125511 scopus 로고    scopus 로고
    • Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase
    • TANAKA, S., and J. F. DIFFLEY, 2002 Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat. Cell Biol. 4: 198-207.
    • (2002) Nat. Cell Biol , vol.4 , pp. 198-207
    • TANAKA, S.1    DIFFLEY, J.F.2
  • 39
    • 0030849742 scopus 로고    scopus 로고
    • Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
    • TANAKA, T., D. KNAPP and K. NASMYTH, 1997 Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell 90: 649-660.
    • (1997) Cell , vol.90 , pp. 649-660
    • TANAKA, T.1    KNAPP, D.2    NASMYTH, K.3
  • 40
    • 33745763705 scopus 로고    scopus 로고
    • Genomewide analysis of rereplication reveals inhibitory controls that target multiple stages of replication initiation
    • TANNY, R. E., D. M. MACALPINE, H. G. BLITZBLAU and S. P. BELL, 2006 Genomewide analysis of rereplication reveals inhibitory controls that target multiple stages of replication initiation. Mol. Biol. Cell 17: 2415-2423.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2415-2423
    • TANNY, R.E.1    MACALPINE, D.M.2    BLITZBLAU, H.G.3    BELL, S.P.4
  • 41
    • 0030693087 scopus 로고    scopus 로고
    • CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
    • VISINTIN, R., S. PRINZ and A. AMON, 1997 CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278: 460-463.
    • (1997) Science , vol.278 , pp. 460-463
    • VISINTIN, R.1    PRINZ, S.2    AMON, A.3
  • 42
    • 0036682094 scopus 로고    scopus 로고
    • APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit
    • WASCH, R., and F. R. CROSS, 2002 APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit. Nature 418: 556-562.
    • (2002) Nature , vol.418 , pp. 556-562
    • WASCH, R.1    CROSS, F.R.2
  • 43
    • 2442528837 scopus 로고    scopus 로고
    • Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch
    • WILMES, G. M., V. ARCHAMBAULT, R. J. AUSTIN, M. D. JACOBSON, S. P. Bell et al., 2004 Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. Genes Dev. 18: 981-991.
    • (2004) Genes Dev , vol.18 , pp. 981-991
    • WILMES, G.M.1    ARCHAMBAULT, V.2    AUSTIN, R.J.3    JACOBSON, M.D.4    Bell, S.P.5
  • 44
    • 0034958791 scopus 로고    scopus 로고
    • Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase
    • YEONG, F. M., H. H. LIM, Y. WANG and U. SURANA, 2001 Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase. Mol. Cell. Biol. 21: 5071-5081.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 5071-5081
    • YEONG, F.M.1    LIM, H.H.2    WANG, Y.3    SURANA, U.4


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