CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice

Circulation

Volumn 117, Issue 10, 2008, Pages 1292-1301

  Olofsson, Peder S ^a   Söderström, Leif Å ^a   Wågsäter, Dick ^b   Sheikine, Yuri ^a,c   Ocaya, Pauline ^b   Lang, François ^d   Rabu, Catherine ^d   Chen, Lieping ^e   Rudling, Mats ^a   Aukrust, Pål ^f   Hedin, Ulf ^a   Paulsson Berne, Gabrielle ^a   Sirsjö, Allan ^b   Hansson, Göran K ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b ÖREBRO UNIVERSITY   (Sweden)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d INSERM   (France)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF OSLO   (Norway)

Author keywords

Atherosclerosis; Cardiovascular diseases; Immunology; Inflammation; Plaque

Indexed keywords

CD137 ANTIGEN; CELL ADHESION MOLECULE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL CULTURE; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; T LYMPHOCYTE ACTIVATION;

4-1BB LIGAND; ANIMALS; ANTIGENS, CD137; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CAROTID ARTERIES; CELLS, CULTURED; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; HYPERCHOLESTEROLEMIA; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RENAL ARTERY; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 40549112657     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.699173     Document Type: Article

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