Relative abilities of 4-1BB (CD137) and CD28 to co-stimulate the response of cytokine deflected Th1 and Th2 cells

Immunobiology

Volumn 200, Issue 2, 1999, Pages 246-263

  Vinay, Dass S ^a   Kwon, Byoung S ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Ulsan   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0033047293     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0171-2985(99)80074-6     Document Type: Article

References (39)

1. MOSMANN, T. R., and R. L. COFFMAN. 1989. Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7: 145.
2. CHERWINSKI, H. M., J. H. SCHUMACHER, K. D. BROWN, and T. R. MOSMANN. 1987. Two types of mouse helper T cell clones. III. Further hybridization, functionally monospecific bioassays and monoclonal antibodies. J. Exp. Med. 166: 1229.
3. LICHTMAN, A. H., J. CHIN, J. A. SCHMIDT, and A. K. ABBAS. 1988. Role of interleukin-1 in the activation of T lymphocytes. Proc. Natl. Acad. Sci. USA 85: 9699.
4. KWON, B. S., and S. M. WEISMANN. 1989. cDNA sequences of two inducible T cell genes. Proc. Natl. Acad. Sci. U.S.A. 86: 1963.
5. POLLOK, K. E., Y.-J. KIM, Z. ZHOU, J. HURTADO, K. K. KIM, R. T. PLICHARD, and B. S. KWON. 1993. Inducible T cell antigen. Analysis of expression and function. J. Immunol. 150: 771.
6. ZHOU, Z., K. E. POLLOK, K. K. KIM, Y.-J. KIM, and B. S. KWON. 1994. Functional analysis of T cell antigen 4-1BB in activated intestinal intra-epithelial T lymphocytes. Immunol. Letts. 41: 177.
7. + T cell proliferation and leads to the amplification of in vivo cytotoxic T cell responses. J. Exp. Med. 186: 46.
8. JANG, I.-K., Z. H. LEE, Y.-K. KIM, S. H. KIM, and B. S. KWON. 1998. Human 4-1BB (CD137) signals are mediated by TRAF2 and activate nuclear factor-κB (NF-κB). Biophys. Biochem. Res. Commun. 242: 613.
9. ARCH, R. H., and C. B. THOMPSON. 1998. 4-1BB and OX-40 are members of tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κB. Mol. Cell. Biol. 18: 558.
10. kk. J. Immunol. 151: 1255.
11. HURTADO, J., Y.-J. KIM, and B. S. KWON. 1997. Signals generated through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-.induced cell death. J. Immunol. 158: 2600.
12. MELERO, I., W. W. SHUFORD, S. A. NEWSBY, A. ARUFFO, J. A. LEDBETTER, K. E. HELLSTROM, R. S. MITTLER, and L. CHEN. 1997. Monoclonal antibodies against 4-1BB T cell activation molecule eradicate established tumors. Nature Med. 3: 682.
13. WANG, S., Y.-J. KIM, C. BICK, S. H. KIM, and B. S. KWON. 1988. The potential roles of 4-1BB costimulation in HIV type 1 infection. AIDS Res. Human Retroviruses 14: 223.
14. HURTADO, J., S. H. KIM, K. E. POLLOK, Z. H, LEE, and B. S, KWON. 1995. Potential role of 4-1BB in T cell activation: Comparison with the costimulatory molecule CD28. J. Immunol. 155: 3360.
15. DEBENEDETTE, M. A., A. SHAHNIAN, T. W. MAK, and T. H. WATTS. 1997. Costimulation of CD28-deficient T lymphocytes by 4-1BB ligand. J. Immunol. 158: 551.
16. + mature thymocytes. J. Immunol. 144: 1646.
17. ARUFFO, A., and B. SEED. 1987. Molecular cloning of a CD28 cDNA by a high efficiency COS cell expression system. Proc. Natl. Acad. Sci. U.S.A. 84: 8573.
18. JUNE, C. H., J. A. BLUESTONE, L. M. NADLER, and C. B. THOMPSON. 1994. The B7 and CD28 receptor families. Immunol. Today 15: 321.
19. GROSS, J. A., E. CALLS, and J. P. ALLISON. 1992. Identification and distribution of the costimulatory receptor CD28 in the mouse. J. Immunol. 149: 380.
20. FREEMAN, G. J., A. S. FREEDMAN, J. M. SEGIL, G. LEE, J. F. WHITMAN, and L. M. NADLER. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143: 2714.
21. AZUMA, M., D. ITO, H. YAGITA, K. OKUMURA, J. H. PHILLIPS, L. L. LANIER, and C. SOMOZA. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366: 76.
22. THOMPSON, C. B. 1995. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation. Cell 81: 979.
23. SCHWARTZ, R. H. 1992. Costimulation of T lymphocytes: The role of CD28, CTLA-4, and B7/BB1 in interleukin production and immunotherapy. Cell 71: 1065.
24. THOMPSON, C. B., T. LINDSTEIN, J. A. LEDBETTER, S. L. KUNKEL, H. A. YOUNG, S. G. EMERSON, J. M. LEIDEN, and C. H. JUNE. 1989. CD28 activation pathway regulates the production of multiple T cell derived lymphokines/cytokines. Proc. Natl. Acad. Sci. U.S.A. 86: 1333.
25. TRINCHIERI, G., and P. SCOTT. 1995. The role of interleukin 12 in the immune response, disease and therapy. Immunol. Today 15: 460.
26. + T cells. Annu. Rev. Immunol. 12: 635.
27. BOHJANEN, P. R., M. OKAJIMA, and R. J. HODES. 1990. Differential regulation of interleukin 4 and interleukin 5 gene expression: A comparison of T cell gene induction by anti-CD3 antibody or by exogeneous lymphokines. Proc. Natl. Acad. Sci. U.S.A. 87: 5283.
28. WATSON, G. A., and D. M. LOPEZ. 1995. Aberrant antigen presentation by macrophages from tumor-bearing mice is involved in the down-regulation of their T cell responses. J. Immunol. 155: 3124.
29. HANDEL-FERNANDEZ, M. E., X. CHENG, L. M. HERBST, and D. M. LOPEZ. 1997. Down-regulation of IL-12, not a shift from a T helper-1 to T helper-2 phenotype, is responsible for impaired IFN-γ production in mammary tumor-bearing mice. J. Immunol. 158: 280.
30. POLLOK, K. E., S. H. KIM, and B. S. KWON. 1995. Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin 2 and interleukin 4. Eur. J. Immunol. 25: 488.
31. PICOTTI, J. R., S. Y. CHAN, R. E. GOODMAN, J. MAGRAM, E. J. EICHWALD, and D. K. BISHOP. 1996. IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection. J. Immunol. 157: 1951.
32. HSIEH, C.-S., A. B. HIEMBEGER, J. S. GOLD, A. O'GARRA, and K. M. MURPHY. 1992. Differential regulation of T helper phenotype development by interleukin 4 and 10 in an αβ-T cell receptor transgenic system. Proc. Natl. Acad. Sci. U.S.A. 89: 6065.
33. PEARLMAN, E., F. P. HEINZEL, F. E. HAZLETT, Jr., and J. W. KAZURA. 1995. ILO-12 modulation of T helper responses to the filarial helminth, Brugia malayi. J. Immunol. 154: 4658.
34. 2 subunit expression in developing T helper 1 (Zh1) and Th2 cells. J. Exp. Med. 185: 817.
35. MANETTI, R., P: PARRONCHI, M. G. GUIDIZI, M. P. PICCINI, E. MAGGI, G. TRINCHIERI, and S. ROMAGNANI. 1993. Natural killer cell stimulatory factor (interleukin-12 [IL-12]) induces T helper 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J. Exp. Med. 177: 1199.
36. - T cells. J. Immunol. 28: 881.
37. LANGSTEIN, J., J. MICHEL, J. FRITSCHE, M. KREUTZ, R. ANDERSEN, and H. SCHWARZ. 1998. CD137 (ILA/4-1BB), a member of the TNF receptor family induces monocyte activation via bidirectional signaling. J. Immunol. 160: 2488.
38. REINER, S. L., and R. M. LOCKSLEY. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13: 151.
39. PHILLIP, S. 1993. IL-12: Initiation cytokine for cell-mediated immunity. Science 260: 496.