Loss of α3/α4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to α5α6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice

Journal of the American Society of Nephrology

Volumn 17, Issue 7, 2006, Pages 1962-1969

  Kang, Jeong Suk ^a   Wang, Xu Ping ^a   Miner, Jeffrey H ^b   Morello, Roy ^c   Sado, Yoshikazu ^d   Abrahamson, Dale R ^e   Borza, Dorin Bogdan ^a,f  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d Shigei Medical Research Institute   (Japan)

^e UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3ALPHA4 COLLAGEN IV; ALPHA5ALPHA6 COLLAGEN IV; COLLAGEN TYPE 4; ISOPROTEIN; UNCLASSIFIED DRUG;

ALPORT SYNDROME; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; COL4A3 GENE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; GENE; GENE LOCUS; GENE MUTATION; GLOMERULUS BASEMENT MEMBRANE; KIDNEY FAILURE; LMX1B GENE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; SURVIVAL; X CHROMOSOME; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DISEASE MODEL; GENETICS; GLOMERULUS; METABOLISM; NEPHRITIS; TRANSGENIC MOUSE;

ANIMALS; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; GLOMERULAR BASEMENT MEMBRANE; KIDNEY GLOMERULUS; MICE; MICE, TRANSGENIC; NEPHRITIS, HEREDITARY; PROTEIN ISOFORMS; SURVIVAL; X CHROMOSOME;

EID: 33745841589     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006020165     Document Type: Article

References (31)

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