PDGF-BB Enhances α1β1 Integrin-Mediated Activation of the ERK/AP-1 Pathway Involved in Collagen Matrix Remodeling by Rat Mesangial Cells

Journal of Cellular Physiology

Volumn 198, Issue 3, 2004, Pages 470-478

  Kagami, Shoji ^a   Urushihara, Maki ^a   Kitamura, Akiko ^a   Kondo, Shuji ^a   Hisayama, Tetsuhiro ^b   Kitamura, Masanori ^c   Löster, Klemens ^d   Reutter, Werner ^d   Kuroda, Yasuhiro ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALPHA1 INTEGRIN; BETA1 INTEGRIN; COLLAGEN; COLLAGEN TYPE 1; CURCUMIN; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NITRILE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; PROTEIN INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1;

ANIMAL; ANIMAL CELL; ANTIBODY DETECTION; ARTICLE; CELL MIGRATION; CELL MOTION; COLLAGEN METABOLISM; CONTROLLED STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME REGULATION; EXTRACELLULAR MATRIX; GEL MOBILITY SHIFT ASSAY; GEL SHIFT ASSAY; GENE MUTATION; GENETIC TRANSFECTION; GLOMERULONEPHRITIS; MESANGIUM; MESANGIUM CELL; METABOLISM; MUTATION; NONHUMAN; ONCOGENE; PATHOGENESIS; PATHOPHYSIOLOGY; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BUTADIENES; CELL MOVEMENT; COLLAGEN; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; GENES, JUN; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS; INTEGRIN ALPHA1BETA1; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NITRILES; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 1242294522     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10433     Document Type: Article

References (35)

1. Barchowsky A, Frleta D, Vincenti MP. 2000. Integration of the NF-κB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: Divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts. Cytokine 12:1469-1479.
2. Bokemeyer D, Ostendorf T, Kunter U, Lindemann M, Kramer HJ, Floege J. 2000. Differential activation of mitogen-activated protein kinases in experimental mesangialproliferative glomerulonephritis. J Am Soc Nephrol 11:232-240.
3. Bokemeyer D, Panek D, Kramer HJ, Lindemann M, Kitahara M, Boor P, Kerjaschki D, Trzaskos JM, Floege J, Ostendorf T. 2002. In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis. J Am Soc Nephrol 13:1473-1480.
4. Border WA, Noble NA. 1994. Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292.
5. Choudhury GG, Karamitsos C, Hernandez J, Gentilini A, Bardgette J, Abboud HE. 1997. PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF. Am J Physiol 273(6 Pt 2):F931-F938.
6. Christerson LB, Gallagher E, Vanderbilt CA, Whitehurst AW, Wells C, Kazempour R, Sternweis PC, Cobb MH. 2002. p115 Rho GTPase activating protein interacts with MEKK1. J Cell Physiol 192:200-208.
7. Cook HT, Khan SB, Allen A, Bhangal G, Smith J, Lobb RR, Pusey CD. 2002. Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis. Am J Pathol 161:1265-1272.
8. Crean JK, Finlay D, Murphy M, Moss C, Godson C, Martin F, Brady HR. 2001. The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. J Biol Chem 277:44187-44194.
9. Danen EH, Yamada KM. 2001. Fibronectin, integrins and growth control. J Cell Physiol 189:1-13.
10. Floege J, Eng E, Young BA, Couser WG, Johnson RJ. 1993. Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis. Kidney Int 43:369-380.
11. Giancotti FG, Ruoslahti E. 1999. Integrin signaling. Science 285:1028-1032.
12. Glass WF II, Teng PR, Haney LB. 1996. Extracellular matrix distribution and hillock formation in human mesangial cells in culture without serum. J Am Soc Nephrol 7:2230-2243.
13. Hagemann C, Blank JL. 2001. The ups and downs of MEK kinase interactions. Cell Signal 13:863-875.
14. Haseley LA, Hugo C, Reidy MA, Johnson RJ. 1999. Dissociation of mesangial cell migration and proliferation in experimental glomerulonephritis. Kidney Int 56:964-972.
15. Hattori Y, Suzuki M, Hattori S, Kasai K. 2002. Vascular smooth muscle cell activation by glycated albumin (Amadori adducts). Hypertension 39:22-28.
16. Hu Y, Zou Y, Dietrich H, Wick G, Xu Q. 1999. Inhibition of neointima hyperplasia of mouse vein grafts by locally applied suramin. Circulation 100:861-868.
17. Hugo C, Shankland SJ, Bowen-Pope DF, Couser WG, Johnson RJ. 1997. Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus. J Clin Invest 100:786-794.
18. Kagami S, Kondo S, Löster K, Reutter W, Kuhara T, Yasutomo K, Kuroda Y. 1999. α1β1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB. J Am Soc Nephrol 10:779-789.
19. Kagami S, Kondo S, Urushihara M, Löster K, Reutter W, Saijo T, Kitamura A, Kobayashi S, Kuroda Y. 2000. Overexpression of α1β1 integrin directly affects rat mesangial cell behavior. Kidney Int 58:1088-1097.
20. Kagami S, Urushihara M, Kondo S, Löster K, Reutter W, Tamaki T, Yoshizumi M, Kuroda Y. 2001. Requirement for tyrosine kinase-ERK1/2 signaling in α1β1 integrin-mediated collagen matrix remodeling by rat mesangial cells. Exp Cell Res 268:274-283.
21. Kagami S, Urushihara M, Kondo S, Hayashi T, Yamano H, Löster K, Vossmeyer D, Reutter W, Kuroda Y. 2002. Effects of anti-α1 integrin subunit antibody on anti-Thy-1 glomerulonephritis. Lab Invest 82:1219-1227.
22. Kuhara T, Kagami S, Kuroda Y. 1997. Expression of β1-integrins on activated mesangial cells in human glomerulonephritis. J Am Soc Nephrol 8:1679-1687.
23. Lai CF, Chaudhary L, Fausto A, Halstead LR, Ory DS, Avioli LV, Cheng SL. 2001. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem 276:14443-14450.
24. Malliri A, Symons M, Hennigan RF, Hurlstone AF, Lamb RF, Wheeler T, Ozanne BW. 1998. The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearran gements, motility, and in vitro invasion of A431 cells. J Cell Biol 143:1087-1099.
25. Naito S, Shimizu S, Maeda S, Wang J, Paul R, Fagin JA. 1998. Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells. Am J Physiol 274(2 Pt 2):C472-C480.
26. Petrak D, Memon SA, Birrer MJ, Ashwell JD, Zacharchuk CM. 1994. Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription. J Immunol 153:2046-2051.
27. Prols F, Hartner A, Schöcklmann HO, Sterzel RB. 1999. Mesangial cells and their adhesive properties. Exp Nephrol 7:137-146.
28. Ravanti L, Heino J, Lopez-Otin C, Kahari VM. 1999. Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J Biol Chem 274:2446-2455.
29. Sakurai H, Shigemori N, Hisada Y, Ishizuka T, Kawashima K, Sugita T. 1997. Suppression of NF-κB and AP-1 activation by glucocorticoids in experimental glomerulonephritis in rats: Molecular mechanisms of anti-nephritic action. Biochim Biophys Acta 1362:252-262.
30. Seto M, Kim S, Yoshifusa H, Nakamura Y, Masuda T, Hamaguchi A, Yamanaka S, Iwao H. 1998. Effects of prednisolone on glomerular signal transduction cascades in experimental glomerulonephritis. J Am Soc Nephrol 9:1367-1376.
31. Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, Damsky CH, Schlaepfer DD. 2000. FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol 2:249-256.
32. Suzaki Y, Yoshizumi M, Kagami S, Koyama AH, Taketani Y, Houchi H, Tsuchiya K, Takeda E, Tamaki T. 2002. Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: Potential role in cell survival following oxidative insults. J Biol Chem 277:9614-9621.
33. Xu J, Zutter MM, Santoro SA, Clark RA. 1996. PDGF induction of α2 integrin gene expression is mediated by protein kinase C-zeta. J Cell Biol 134:1301-1311.
34. Xu J, Zutter MM, Santoro SA, Clark RA. 1998. A three-dimensional collagen lattice activates NF-κB in human fibroblasts: Role in integrin α2 gene expression and tissue remodeling. J Cell Biol 140:709-719.
35. Yoon SO, Kim MM, Chung AS. 2001. Inhibitory effect of selenite on invasion of HT1080 tumor cells. J Biol Chem 276:20085-20092.