Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway

Acta Pharmacologica Sinica

Volumn 25, Issue 8, 2004, Pages 1077-1082

  Huo, Rui ^a,b   Zhou, Qiu Li ^b   Wang, Ben Xiang ^c   Tashiro, Shin Ichi ^d   Onodera, Satoshi ^d   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

^c CHANGCHUN UNIVERSITY OF CHINESE MEDICINE   (China)

^d SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspases; Diosgenin; HeLa cells; Mitochondria

Indexed keywords

BENZYLOXYCARBONYLALANYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BROXURIDINE; CASPASE; CASPASE 10 INHIBITOR; CASPASE 3 INHIBITOR; CASPASE 8 INHIBITOR; CASPASE 9 INHIBITOR; CASPASE INHIBITOR; DIOSGENIN; DNA FRAGMENT; PROTEIN BCL 2; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PROTEIN EXPRESSION; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASES; CELL CYCLE; CELL DIVISION; DIOSGENIN; DNA FRAGMENTATION; DOWN-REGULATION; HELA CELLS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; OLIGOPEPTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 4043084804     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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