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Volumn 49, Issue 2, 2008, Pages 132-141

Evaluating genotoxicity data to identify a mode of action and its application in estimating cancer risk at low doses: A case study involving carbon tetrachloride

Author keywords

Carbon tetrachloride; Genotoxicity; Mode of action; Risk assessment; Toxicity

Indexed keywords

CARBON TETRACHLORIDE;

EID: 40149109789     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20368     Document Type: Conference Paper
Times cited : (25)

References (87)
  • 1
    • 0020954911 scopus 로고
    • The morphological transformation of Syrian hamster embryo cells by chemicals reportedly nonmutagenic to Salmonella typhimurium
    • Amacher DE, Zelljadt I. 1983. The morphological transformation of Syrian hamster embryo cells by chemicals reportedly nonmutagenic to Salmonella typhimurium. Carcinogenesis 4:291-295.
    • (1983) Carcinogenesis , vol.4 , pp. 291-295
    • Amacher, D.E.1    Zelljadt, I.2
  • 2
    • 1542618516 scopus 로고    scopus 로고
    • Mutagenicity of carbon tetrachloride and chloroform in Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2uvrA/pKM101 and WP2/pKM101, using a gas exposure method
    • Araki A, Kamigaito N, Sasaki T, Matsushima T. 2004. Mutagenicity of carbon tetrachloride and chloroform in Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2uvrA/pKM101 and WP2/pKM101, using a gas exposure method Environ Mol Mutagen 43:128-133.
    • (2004) Environ Mol Mutagen , vol.43 , pp. 128-133
    • Araki, A.1    Kamigaito, N.2    Sasaki, T.3    Matsushima, T.4
  • 4
    • 34547935761 scopus 로고    scopus 로고
    • Living with p53, dying of p53
    • Aylon Y, Oren M. 2007. Living with p53, dying of p53. Cell 130:597-600.
    • (2007) Cell , vol.130 , pp. 597-600
    • Aylon, Y.1    Oren, M.2
  • 5
    • 0020966575 scopus 로고
    • Evaluation of DNA damage by the alkaline elution technique in liver, kidneys and lungs of rats and hamsters treated with N-nitrosodialkylamines
    • Barbin A, Bereziat JC, Bartsch H. 1983. Evaluation of DNA damage by the alkaline elution technique in liver, kidneys and lungs of rats and hamsters treated with N-nitrosodialkylamines. Carcinogenesis 4:541-545.
    • (1983) Carcinogenesis , vol.4 , pp. 541-545
    • Barbin, A.1    Bereziat, J.C.2    Bartsch, H.3
  • 6
    • 0347298806 scopus 로고    scopus 로고
    • Chloroform, carbon tetrachloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress
    • Beddowes EJ, Faux SP, Chipman JK. 2003. Chloroform, carbon tetrachloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress. Toxicology 187:101-115.
    • (2003) Toxicology , vol.187 , pp. 101-115
    • Beddowes, E.J.1    Faux, S.P.2    Chipman, J.K.3
  • 7
    • 0027171488 scopus 로고
    • Quantitative structure-activity relationship models correctly predict the toxic and aneuploidizing properties of six halogenated methanes in Aspergillus nidulans
    • Benigni R, Andreoli C, Conti L, Tafani P, Cotta-Ramusino M, Carere A, Crebelli R. 1993. Quantitative structure-activity relationship models correctly predict the toxic and aneuploidizing properties of six halogenated methanes in Aspergillus nidulans. Mutagen 8:301-305.
    • (1993) Mutagen , vol.8 , pp. 301-305
    • Benigni, R.1    Andreoli, C.2    Conti, L.3    Tafani, P.4    Cotta-Ramusino, M.5    Carere, A.6    Crebelli, R.7
  • 8
    • 0020398980 scopus 로고
    • Detection of DNA damage in primary cultures of rat hepatocytes following in vivo and in vitro exposure to genotoxic agents
    • Bermudez E, Mirsalis JC, Eales HC. 1982. Detection of DNA damage in primary cultures of rat hepatocytes following in vivo and in vitro exposure to genotoxic agents. Environ Mutagen 4:667-679.
    • (1982) Environ Mutagen , vol.4 , pp. 667-679
    • Bermudez, E.1    Mirsalis, J.C.2    Eales, H.C.3
  • 9
    • 0037444282 scopus 로고    scopus 로고
    • Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division
    • Betti CJ, Villalobos MJ, Diaz MO, Vaughan AT. 2003. Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division. Cancer Res 63:1377-1381.
    • (2003) Cancer Res , vol.63 , pp. 1377-1381
    • Betti, C.J.1    Villalobos, M.J.2    Diaz, M.O.3    Vaughan, A.T.4
  • 10
    • 0020662454 scopus 로고
    • Viscometric detection of liver DNA fragmentation in rats treated with minimal doses of chemical carcinogens
    • Brambilla G, Carlo P, Finollo R, Bignone FA, Ledda A, Cajelli E. 1983. Viscometric detection of liver DNA fragmentation in rats treated with minimal doses of chemical carcinogens. Cancer Res 43:202-209.
    • (1983) Cancer Res , vol.43 , pp. 202-209
    • Brambilla, G.1    Carlo, P.2    Finollo, R.3    Bignone, F.A.4    Ledda, A.5    Cajelli, E.6
  • 11
    • 0032472889 scopus 로고    scopus 로고
    • Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae
    • Brennan RJ, Schiestl RH. 1998. Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae. Mutat Res 397:271-278.
    • (1998) Mutat Res , vol.397 , pp. 271-278
    • Brennan, R.J.1    Schiestl, R.H.2
  • 14
    • 0018839948 scopus 로고
    • Cytochrome P-450 mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae
    • Callen DF, Wolf CR, Philpot RM. 1980. Cytochrome P-450 mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae. Mutat Res 77:55-63.
    • (1980) Mutat Res , vol.77 , pp. 55-63
    • Callen, D.F.1    Wolf, C.R.2    Philpot, R.M.3
  • 15
    • 0024589137 scopus 로고
    • Species differences in the interaction between CCl4 reactive metabolites and liver DNA or nuclear protein fractions
    • Castro GD, Diaz Gomez MI, Castro JA. 1989. Species differences in the interaction between CCl4 reactive metabolites and liver DNA or nuclear protein fractions. Carcinogenesis 10:289-294.
    • (1989) Carcinogenesis , vol.10 , pp. 289-294
    • Castro, G.D.1    Diaz Gomez, M.I.2    Castro, J.A.3
  • 16
    • 0025074225 scopus 로고
    • Biotransformation of carbon tetrachloride and lipid peroxidation promotion by liver nuclear preparations from different animal species
    • Castro GD, Diaz Gomez MI, Castro JA. 1990. Biotransformation of carbon tetrachloride and lipid peroxidation promotion by liver nuclear preparations from different animal species. Cancer Lett 53:9-15.
    • (1990) Cancer Lett , vol.53 , pp. 9-15
    • Castro, G.D.1    Diaz Gomez, M.I.2    Castro, J.A.3
  • 18
    • 0034654638 scopus 로고    scopus 로고
    • Deoxyguanosine adducts of t-4-hydroxy-2-nonenal are endogenous DNA lesions in rodents and humans: Detection and potential sources
    • Chung FL, Nath RG, Ocando J, Nishikawa A, Zhang L. 2000. Deoxyguanosine adducts of t-4-hydroxy-2-nonenal are endogenous DNA lesions in rodents and humans: Detection and potential sources Cancer Res 60:1507-1511.
    • (2000) Cancer Res , vol.60 , pp. 1507-1511
    • Chung, F.L.1    Nath, R.G.2    Ocando, J.3    Nishikawa, A.4    Zhang, L.5
  • 19
    • 0025168534 scopus 로고
    • Cell proliferation in carcinogenesis
    • Cohen SM, Ellwein LB. 1990. Cell proliferation in carcinogenesis. Science 249:1007-1011.
    • (1990) Science , vol.249 , pp. 1007-1011
    • Cohen, S.M.1    Ellwein, L.B.2
  • 20
    • 0018654270 scopus 로고
    • Analysis of anaphase in cell culture: An adequate test system for the distinction between compounds which selectively alter the chromosome structure or the mitotic apparatus
    • Coutino RR. 1979. Analysis of anaphase in cell culture: An adequate test system for the distinction between compounds which selectively alter the chromosome structure or the mitotic apparatus. Environ Health Perspect 31:131-136.
    • (1979) Environ Health Perspect , vol.31 , pp. 131-136
    • Coutino, R.R.1
  • 21
    • 0018104226 scopus 로고
    • De novo and repair replication of DNA in liver of carcinogen-treated animals
    • Craddock VM, Henderson AR. 1978. De novo and repair replication of DNA in liver of carcinogen-treated animals. Cancer Res 38:2135-2143.
    • (1978) Cancer Res , vol.38 , pp. 2135-2143
    • Craddock, V.M.1    Henderson, A.R.2
  • 22
    • 0023712114 scopus 로고
    • Induction of chromosome malsegregation by halogenated organic solvents in Aspergillus nidulans: Unspecific or specific mechanism?
    • Crebelli R, Benigni R, Franekic J, Conti G, Conti L, Carere A. 1988. Induction of chromosome malsegregation by halogenated organic solvents in Aspergillus nidulans: Unspecific or specific mechanism? Mutat Res 201:401-411.
    • (1988) Mutat Res , vol.201 , pp. 401-411
    • Crebelli, R.1    Benigni, R.2    Franekic, J.3    Conti, G.4    Conti, L.5    Carere, A.6
  • 23
    • 0029197397 scopus 로고
    • Toxicology of halogenated aliphatic hydrocarbons: Structural and molecular determinants for the disturbance of chromosome segregation and the induction of lipid peroxidation
    • Crebelli R, Andreoli C, Carere A, Conti L, Crochi B, Cotta-Ramusino M, Benigni R. 1995. Toxicology of halogenated aliphatic hydrocarbons: Structural and molecular determinants for the disturbance of chromosome segregation and the induction of lipid peroxidation. Chem Biol Interact 98:113-129.
    • (1995) Chem Biol Interact , vol.98 , pp. 113-129
    • Crebelli, R.1    Andreoli, C.2    Carere, A.3    Conti, L.4    Crochi, B.5    Cotta-Ramusino, M.6    Benigni, R.7
  • 25
    • 0014275831 scopus 로고
    • Chromosome aberrations in liver forced to regenerate by chemical or surgical methods
    • Curtis HJ, Tilley J. 1968. Chromosome aberrations in liver forced to regenerate by chemical or surgical methods. J Gerontol 23:140-141.
    • (1968) J Gerontol , vol.23 , pp. 140-141
    • Curtis, H.J.1    Tilley, J.2
  • 26
    • 2942523593 scopus 로고    scopus 로고
    • Endogenous DNA damage in humans: A review of quantitative data
    • De Bont R, van Larebeke N. 2004. Endogenous DNA damage in humans: A review of quantitative data. Mutagen 19:169-185.
    • (2004) Mutagen , vol.19 , pp. 169-185
    • De Bont, R.1    van Larebeke, N.2
  • 27
    • 0021256974 scopus 로고
    • Genotoxic activity and potency of 135 compounds in the Ames reversion test and in a bacterial DNA-repair test
    • De Flora S, Zanacchi P, Camoirano A, Bennicelli C, Badolati GS. 1984. Genotoxic activity and potency of 135 compounds in the Ames reversion test and in a bacterial DNA-repair test. Mutat Res 133:161-198.
    • (1984) Mutat Res , vol.133 , pp. 161-198
    • De Flora, S.1    Zanacchi, P.2    Camoirano, A.3    Bennicelli, C.4    Badolati, G.S.5
  • 28
    • 0019145673 scopus 로고
    • Covalent binding of carbon tetrachloride metabolites to liver nuclear DNA, proteins, and lipids
    • Diaz Gomez MI, Castro JA. 1980. Covalent binding of carbon tetrachloride metabolites to liver nuclear DNA, proteins, and lipids. Toxicol Appl Pharmacol 56:199-206.
    • (1980) Toxicol Appl Pharmacol , vol.56 , pp. 199-206
    • Diaz Gomez, M.I.1    Castro, J.A.2
  • 29
    • 0019947789 scopus 로고
    • Microsomal bioactivation and covalent binding of aliphatic halides to DNA
    • DiRenzo AB, Gandolfi AJ, Sipes IG. 1982. Microsomal bioactivation and covalent binding of aliphatic halides to DNA. Toxicol Lett 11:243-252.
    • (1982) Toxicol Lett , vol.11 , pp. 243-252
    • DiRenzo, A.B.1    Gandolfi, A.J.2    Sipes, I.G.3
  • 30
    • 0029880271 scopus 로고    scopus 로고
    • An investigation into the activation and deactivation of chlorinated hydrocarbons to genotoxins in metabolically competent human cells
    • Doherty AT, Ellard S, Parry EM, Parry JM. 1996. An investigation into the activation and deactivation of chlorinated hydrocarbons to genotoxins in metabolically competent human cells. Mutagen 11:247-274.
    • (1996) Mutagen , vol.11 , pp. 247-274
    • Doherty, A.T.1    Ellard, S.2    Parry, E.M.3    Parry, J.M.4
  • 31
    • 0028933548 scopus 로고
    • Salmonella test positive and negative carcinogens show different effects on intrachromosomal recombination in G2 cell cycle arrested yeast cells
    • Galli A, Schiestl RH. 1995. Salmonella test positive and negative carcinogens show different effects on intrachromosomal recombination in G2 cell cycle arrested yeast cells. Carcinogenesis 16:659-663.
    • (1995) Carcinogenesis , vol.16 , pp. 659-663
    • Galli, A.1    Schiestl, R.H.2
  • 32
    • 0030273237 scopus 로고    scopus 로고
    • Effects of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in G1-arrested yeast cells
    • Galli A, Schiestl RH. 1996. Effects of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in G1-arrested yeast cells. Mutat Res 370:209-221.
    • (1996) Mutat Res , vol.370 , pp. 209-221
    • Galli, A.1    Schiestl, R.H.2
  • 33
    • 0032501118 scopus 로고    scopus 로고
    • Effect of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in S-phase arrested yeast cells
    • Galli A, Schiestl RH. 1998. Effect of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in S-phase arrested yeast cells. Mutat Res 419:53-68.
    • (1998) Mutat Res , vol.419 , pp. 53-68
    • Galli, A.1    Schiestl, R.H.2
  • 34
    • 0021329006 scopus 로고
    • Liver nuclear DNA synthesis in mice following carbon tetrachloride administration or partial hepatectomy
    • Gans JH, Korson R. 1984. Liver nuclear DNA synthesis in mice following carbon tetrachloride administration or partial hepatectomy. Proc Soc Exp Biol Med 175:237-242.
    • (1984) Proc Soc Exp Biol Med , vol.175 , pp. 237-242
    • Gans, J.H.1    Korson, R.2
  • 35
    • 0021268316 scopus 로고
    • Genotoxicity of the free-radical producers CCl4 and lipoperoxide in Aspergillus nidulans
    • Gualandi G. 1984. Genotoxicity of the free-radical producers CCl4 and lipoperoxide in Aspergillus nidulans. Mutat Res 136:109-114.
    • (1984) Mutat Res , vol.136 , pp. 109-114
    • Gualandi, G.1
  • 36
    • 0034103651 scopus 로고    scopus 로고
    • Examination of lacZ mutant induction in the liver and testis of Muta Mouse following injection of halogenated aliphatic hydrocarbons classified as human carcinogens
    • Hachiya N, Motohashi Y. 2000. Examination of lacZ mutant induction in the liver and testis of Muta Mouse following injection of halogenated aliphatic hydrocarbons classified as human carcinogens. Ind Health 38:213-220.
    • (2000) Ind Health , vol.38 , pp. 213-220
    • Hachiya, N.1    Motohashi, Y.2
  • 37
    • 0025099083 scopus 로고
    • Isolation of a guanine-malondialdehyde adduct from rat and human urine
    • Hadley M, Draper HH. 1990. Isolation of a guanine-malondialdehyde adduct from rat and human urine. Lipids 25:82-85.
    • (1990) Lipids , vol.25 , pp. 82-85
    • Hadley, M.1    Draper, H.H.2
  • 39
    • 0029150827 scopus 로고
    • Differential staining of DNA strand breaks in dying cells by non-radioactive in situ nick translation
    • Hashimoto S, Koji T, Niu J, Kanematsu T, Nakane PK. 1995. Differential staining of DNA strand breaks in dying cells by non-radioactive in situ nick translation. Arch Histol Cytol 58:161-170.
    • (1995) Arch Histol Cytol , vol.58 , pp. 161-170
    • Hashimoto, S.1    Koji, T.2    Niu, J.3    Kanematsu, T.4    Nakane, P.K.5
  • 40
    • 0030665204 scopus 로고    scopus 로고
    • Balance between oxidative damage and proliferative potential in an experimental rat model of CCl4-induced cirrhosis: Protective role of adenosine administration
    • Hernandez-Munoz R, Diaz-Munoz M, Lopez V, Lopez-Barrera F, Yanez L, Vidrio S, Aranda-Fraustro A, Chagoya de Sanchez V. 1997. Balance between oxidative damage and proliferative potential in an experimental rat model of CCl4-induced cirrhosis: Protective role of adenosine administration. Hepatology 26:1100-1110.
    • (1997) Hepatology , vol.26 , pp. 1100-1110
    • Hernandez-Munoz, R.1    Diaz-Munoz, M.2    Lopez, V.3    Lopez-Barrera, F.4    Yanez, L.5    Vidrio, S.6    Aranda-Fraustro, A.7    Chagoya de Sanchez, V.8
  • 42
    • 0032696146 scopus 로고    scopus 로고
    • Carbon Tetrachloride
    • IARC, Lyon, France: International Agency for Research on Cancer. pp
    • IARC. 1999. Carbon Tetrachloride. IARC Monographs on the Evaluatior of Carcinogenic Risks to Humans. Lyon, France: International Agency for Research on Cancer. pp 401-432.
    • (1999) IARC Monographs on the Evaluatior of Carcinogenic Risks to Humans , pp. 401-432
  • 43
    • 0025914503 scopus 로고
    • Biochemical assessment of the genotoxicity of the in vitro interaction between chlordecone and carbon tetrachloride in rat hepatocytes
    • Ikegwuonu FI, Mehendale HM. 1991. Biochemical assessment of the genotoxicity of the in vitro interaction between chlordecone and carbon tetrachloride in rat hepatocytes. J Appl Toxicol 11:303-310.
    • (1991) J Appl Toxicol , vol.11 , pp. 303-310
    • Ikegwuonu, F.I.1    Mehendale, H.M.2
  • 44
    • 0038583217 scopus 로고    scopus 로고
    • IPCS, Geneva, Switzerland: International Programme for Chemical Safety. 177 p
    • IPCS. 1999. Carbon Tetrachloride. Geneva, Switzerland: International Programme for Chemical Safety. 177 p.
    • (1999) Carbon Tetrachloride
  • 45
    • 13844297589 scopus 로고    scopus 로고
    • Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, Hatch GE, Hensley K, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts II LJ, Rokach J, Shigenaga MK, Sohal RS, Sun J, Tice RR, Van Thiel DH, Wellner D, Walter PB, Tomer KB, Mason RP, Barrett JC. 2005. Biomarkers of oxidative stress study II: Are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med 38:698-710.
    • Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, Hatch GE, Hensley K, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts II LJ, Rokach J, Shigenaga MK, Sohal RS, Sun J, Tice RR, Van Thiel DH, Wellner D, Walter PB, Tomer KB, Mason RP, Barrett JC. 2005. Biomarkers of oxidative stress study II: Are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med 38:698-710.
  • 48
    • 0021210674 scopus 로고
    • Binding of carbon tetrachloride metabolites to rat hepatic mitochondrial DNA
    • Levy GN, Brabec MJ. 1984. Binding of carbon tetrachloride metabolites to rat hepatic mitochondrial DNA. Toxicol Lett 22:229-234.
    • (1984) Toxicol Lett , vol.22 , pp. 229-234
    • Levy, G.N.1    Brabec, M.J.2
  • 49
    • 0020347250 scopus 로고
    • Chromosome instability in 101/H and C57BL/6 strain mice during aging
    • Lil'p IG. 1982. Chromosome instability in 101/H and C57BL/6 strain mice during aging. Genetika 18:1976-1982.
    • (1982) Genetika , vol.18 , pp. 1976-1982
    • Lil'p IG1
  • 51
    • 0025648878 scopus 로고
    • Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. V. Results with 46 chemicals
    • Loveday KS, Anderson BE, Resnick MA, Zeiger E. 1990. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. V. Results with 46 chemicals. Environ Mol Mutagen 16:272-303.
    • (1990) Environ Mol Mutagen , vol.16 , pp. 272-303
    • Loveday, K.S.1    Anderson, B.E.2    Resnick, M.A.3    Zeiger, E.4
  • 54
    • 0030604292 scopus 로고    scopus 로고
    • Carbon tetrachloride: Genetic effects and other modes of action
    • McGregor D, Lang M. 1996. Carbon tetrachloride: Genetic effects and other modes of action. Mutat Res 366:181-195.
    • (1996) Mutat Res , vol.366 , pp. 181-195
    • McGregor, D.1    Lang, M.2
  • 55
    • 0023221783 scopus 로고
    • In vivo measurement of unscheduled DNA synthesis and S-phase synthesis as an indicator of hepatocarcinogenesis in rodents
    • Mirsalis JC. 1987. In vivo measurement of unscheduled DNA synthesis and S-phase synthesis as an indicator of hepatocarcinogenesis in rodents. Cell Biol Toxicol 3:165-173.
    • (1987) Cell Biol Toxicol , vol.3 , pp. 165-173
    • Mirsalis, J.C.1
  • 56
    • 0019167752 scopus 로고
    • Detection of unscheduled DNA synthesis in hepatocytes isolated from rats treated with genotoxic agents: An in vivo-in vitro assay for potential carcinogens and mutagens
    • Mirsalis JC, Butterworth BE. 1980. Detection of unscheduled DNA synthesis in hepatocytes isolated from rats treated with genotoxic agents: An in vivo-in vitro assay for potential carcinogens and mutagens. Carcinogenesis 1:621-625.
    • (1980) Carcinogenesis , vol.1 , pp. 621-625
    • Mirsalis, J.C.1    Butterworth, B.E.2
  • 57
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
    • Mirsalis JC, Tyson CK, Butterworth BE. 1982. Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ Mutagen 4:553-562.
    • (1982) Environ Mutagen , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, C.K.2    Butterworth, B.E.3
  • 58
  • 59
    • 0030871409 scopus 로고    scopus 로고
    • Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group
    • Morita T, Asano N, Awogi T, Sasaki YF, Sato S, Shimada H, Sutou S, Suzuki T, Wakata A, Sofuni T, Hayashi M. 1997. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group. Mutat Res 389:3-122.
    • (1997) Mutat Res , vol.389 , pp. 3-122
    • Morita, T.1    Asano, N.2    Awogi, T.3    Sasaki, Y.F.4    Sato, S.5    Shimada, H.6    Sutou, S.7    Suzuki, T.8    Wakata, A.9    Sofuni, T.10    Hayashi, M.11
  • 60
    • 40149094930 scopus 로고    scopus 로고
    • Carbon Tetrachloride
    • NTP, 11th ed. U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program
    • NTP. 2005. Carbon Tetrachloride. Report on Carcinogens, 11th ed. U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
    • (2005) Report on Carcinogens
  • 61
    • 0023228580 scopus 로고    scopus 로고
    • Onfelt A. 1987. Spindle disturbances in mammalian cells. III. Toxicity, c-mitosis and aneuploidy with 22 different compounds Specific and unspecific mechanisms. Mutat Res 182:135-154.
    • Onfelt A. 1987. Spindle disturbances in mammalian cells. III. Toxicity, c-mitosis and aneuploidy with 22 different compounds Specific and unspecific mechanisms. Mutat Res 182:135-154.
  • 62
    • 0023641225 scopus 로고
    • Distribution of carbon tetrachloride-metabolite(s) to DNase I-sensitive and -resistant chromatin
    • Oruambo IF, Van Duuren BL. 1987. Distribution of carbon tetrachloride-metabolite(s) to DNase I-sensitive and -resistant chromatin. Cancer Lett 37:311-316.
    • (1987) Cancer Lett , vol.37 , pp. 311-316
    • Oruambo, I.F.1    Van Duuren, B.L.2
  • 63
    • 0027770002 scopus 로고
    • Imaging of oxidative stress at subcellular level by confocal laser scanning microscopy after fluorescent derivatization of cellular carbonyls
    • Pompella A, Comporti M. 1993. Imaging of oxidative stress at subcellular level by confocal laser scanning microscopy after fluorescent derivatization of cellular carbonyls. Am J Pathol 142:1353-1357.
    • (1993) Am J Pathol , vol.142 , pp. 1353-1357
    • Pompella, A.1    Comporti, M.2
  • 64
    • 0015924846 scopus 로고
    • In vivo and in vitro binding of carbon tetrachloride with nucleic acids and proteins in rat and mouse liver
    • Rocchi P, Prodi G, Grilli S, Ferreri AM. 1973. In vivo and in vitro binding of carbon tetrachloride with nucleic acids and proteins in rat and mouse liver. Int J Cancer 11:419-425.
    • (1973) Int J Cancer , vol.11 , pp. 419-425
    • Rocchi, P.1    Prodi, G.2    Grilli, S.3    Ferreri, A.M.4
  • 65
    • 0023898707 scopus 로고
    • Clastogenic effects induced in mice and rats by 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a phenobarbital-like enzyme inducer and liver tumour promoter
    • Rossi AM, Zaccaro L, Rosselli F, Quattrone C. 1988. Clastogenic effects induced in mice and rats by 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a phenobarbital-like enzyme inducer and liver tumour promoter. Carcinogenesis 9:1147-1151.
    • (1988) Carcinogenesis , vol.9 , pp. 1147-1151
    • Rossi, A.M.1    Zaccaro, L.2    Rosselli, F.3    Quattrone, C.4
  • 66
    • 0023575685 scopus 로고
    • Probable free radical effects on rat liver nuclei during early hepatocarcinogenesis with a choline-devoid low methionine diet
    • Rushmore TH, Ghazarian DM, Subrahmanyan V, Farber E, Ghoshal AK. 1987. Probable free radical effects on rat liver nuclei during early hepatocarcinogenesis with a choline-devoid low methionine diet. Cancer Res 47 (24 Part 1):6731-6740.
    • (1987) Cancer Res , vol.47 , Issue.24 PART 1 , pp. 6731-6740
    • Rushmore, T.H.1    Ghazarian, D.M.2    Subrahmanyan, V.3    Farber, E.4    Ghoshal, A.K.5
  • 67
  • 68
    • 0032501069 scopus 로고    scopus 로고
    • Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs
    • Sasaki YF, Saga A, Akasaka M, Ishibashi S, Yoshida K, Su YQ, Matsusaka N, Tsuda S. 1998. Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs. Mutat Res 419:13-20.
    • (1998) Mutat Res , vol.419 , pp. 13-20
    • Sasaki, Y.F.1    Saga, A.2    Akasaka, M.3    Ishibashi, S.4    Yoshida, K.5    Su, Y.Q.6    Matsusaka, N.7    Tsuda, S.8
  • 69
    • 0025940602 scopus 로고
    • Chromosome aberrations, micronuclei and sister-chromatid exchanges (SCEs) in rat liver induced in vivo by hepatocarcinogens including heterocyclic amines
    • Sawada S, Yamanaka T, Yamatsu K, Furihata C, Matsushima T. 1991. Chromosome aberrations, micronuclei and sister-chromatid exchanges (SCEs) in rat liver induced in vivo by hepatocarcinogens including heterocyclic amines. Mutat Res 251:59-69.
    • (1991) Mutat Res , vol.251 , pp. 59-69
    • Sawada, S.1    Yamanaka, T.2    Yamatsu, K.3    Furihata, C.4    Matsushima, T.5
  • 70
    • 0018742763 scopus 로고
    • DNA damage induced in vivo evaluated with a non-radioactive alkaline elution technique
    • Schwarz M, Hummel J, Appel KE, Rickart R, Kunz W. 1979. DNA damage induced in vivo evaluated with a non-radioactive alkaline elution technique. Cancer Lett 6:221-226.
    • (1979) Cancer Lett , vol.6 , pp. 221-226
    • Schwarz, M.1    Hummel, J.2    Appel, K.E.3    Rickart, R.4    Kunz, W.5
  • 72
    • 0031876158 scopus 로고    scopus 로고
    • Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride
    • Shi J, Aisaki K, Ikawa Y, Wake K. 1998. Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride. Am J Pathol 153:515-525.
    • (1998) Am J Pathol , vol.153 , pp. 515-525
    • Shi, J.1    Aisaki, K.2    Ikawa, Y.3    Wake, K.4
  • 73
    • 0035948830 scopus 로고    scopus 로고
    • The protection of vitamin E, selenium against carbon tetrachloride-induced genotoxicity in ovine peripheral blood lymphocytes
    • Sivikova K, Piesova E, Dianovsky J. 2001. The protection of vitamin E, selenium against carbon tetrachloride-induced genotoxicity in ovine peripheral blood lymphocytes. Mutat Res 494:135-142.
    • (2001) Mutat Res , vol.494 , pp. 135-142
    • Sivikova, K.1    Piesova, E.2    Dianovsky, J.3
  • 74
    • 0019395288 scopus 로고
    • Generation and persistence of carcinogen-induced repair intermediates in rat liver DNA in vivo
    • Stewart BW. 1981. Generation and persistence of carcinogen-induced repair intermediates in rat liver DNA in vivo. Cancer Res 41: 3238-3243.
    • (1981) Cancer Res , vol.41 , pp. 3238-3243
    • Stewart, B.W.1
  • 75
    • 0031458885 scopus 로고    scopus 로고
    • Carbon tetrachloride does not induce micronucleus in either mouse bone marrow or peripheral blood
    • Suzuki H, Hirano N, Watanabe C, Tarumoto Y. 1997. Carbon tetrachloride does not induce micronucleus in either mouse bone marrow or peripheral blood. Mutat Res 394:77-80.
    • (1997) Mutat Res , vol.394 , pp. 77-80
    • Suzuki, H.1    Hirano, N.2    Watanabe, C.3    Tarumoto, Y.4
  • 76
    • 0031907613 scopus 로고    scopus 로고
    • In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: A structure-activity relationship (QSAR) analysis of the genotoxic and cytotoxic potential
    • Tafazoli M, Baeten A, Geerlings P, Kirsch-Volders M. 1998. In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: A structure-activity relationship (QSAR) analysis of the genotoxic and cytotoxic potential. Mutagen 13:115-126.
    • (1998) Mutagen , vol.13 , pp. 115-126
    • Tafazoli, M.1    Baeten, A.2    Geerlings, P.3    Kirsch-Volders, M.4
  • 77
    • 0031978983 scopus 로고    scopus 로고
    • Immunohistochemical detection of 8-hydroxy-2′-deoxyguanosine in paraffin-embedded sections of rat liver after carbon tetrachloride treatment
    • Takahashi S, Hirose M, Tamano S, Ozaki M, Orita S, Ito T, Takeuchi M, Ochi H, Fukada S, Kasai H, et al. 1998. Immunohistochemical detection of 8-hydroxy-2′-deoxyguanosine in paraffin-embedded sections of rat liver after carbon tetrachloride treatment. Toxicol Pathol 26:247-252.
    • (1998) Toxicol Pathol , vol.26 , pp. 247-252
    • Takahashi, S.1    Hirose, M.2    Tamano, S.3    Ozaki, M.4    Orita, S.5    Ito, T.6    Takeuchi, M.7    Ochi, H.8    Fukada, S.9    Kasai, H.10
  • 78
    • 0032808216 scopus 로고    scopus 로고
    • Effect of mitogenic or regenerative cell proliferation on lacz mutant frequency in the liver of MutaTMMice treated with 5, 9-dimethyldibenzo[c,g]carbazole
    • Tombolan F, Renault D, Brault D, Guffroy M, Perin F, Thybaud V. 1999. Effect of mitogenic or regenerative cell proliferation on lacz mutant frequency in the liver of MutaTMMice treated with 5, 9-dimethyldibenzo[c,g]carbazole. Carcinogenesis 20:1357-1362.
    • (1999) Carcinogenesis , vol.20 , pp. 1357-1362
    • Tombolan, F.1    Renault, D.2    Brault, D.3    Guffroy, M.4    Perin, F.5    Thybaud, V.6
  • 79
    • 0028855364 scopus 로고
    • An improved method of mouse liver micronucleus analysis: An application to age-related genetic alteration and polyploidy study
    • Uryvaeva IV, Delone GV. 1995. An improved method of mouse liver micronucleus analysis: an application to age-related genetic alteration and polyploidy study. Mutat Res 334:71-80.
    • (1995) Mutat Res , vol.334 , pp. 71-80
    • Uryvaeva, I.V.1    Delone, G.V.2
  • 80
    • 30344443429 scopus 로고    scopus 로고
    • USEPA, Environmental Protection Agency, EPA/630/P-03/001B. 166 p
    • USEPA. 2005. Guidelines for Carcinogen Risk Assessment. Environmental Protection Agency, EPA/630/P-03/001B. 166 p.
    • (2005) Guidelines for Carcinogen Risk Assessment
  • 81
    • 0029120728 scopus 로고
    • Identification of clastogenic and/or aneugenic events during the preneoplastic stages of experimental rat hepatocarcinogenesis by fluorescence in situ hybridization
    • Van Goethem F, de Stoppelaar J, Hoebee B, Kirsch-Volders M. 1995. Identification of clastogenic and/or aneugenic events during the preneoplastic stages of experimental rat hepatocarcinogenesis by fluorescence in situ hybridization. Carcinogenesis 16:1825-1834.
    • (1995) Carcinogenesis , vol.16 , pp. 1825-1834
    • Van Goethem, F.1    de Stoppelaar, J.2    Hoebee, B.3    Kirsch-Volders, M.4
  • 82
    • 0027448914 scopus 로고
    • Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis
    • Van Goethem F, Ghahroudi MA, Castelain P, Kirsch-Volders M. 1993. Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis. Carcinogenesis 14:2397-2406.
    • (1993) Carcinogenesis , vol.14 , pp. 2397-2406
    • Van Goethem, F.1    Ghahroudi, M.A.2    Castelain, P.3    Kirsch-Volders, M.4
  • 84
    • 0035964580 scopus 로고    scopus 로고
    • Detection of 1,N2-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal after gavage of trans-4-hydroxy-2-nonenal or induction of lipid peroxidation with carbon tetrachloride in F344 rats
    • Wacker M, Wanek P, Eder E. 2001. Detection of 1,N2-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal after gavage of trans-4-hydroxy-2-nonenal or induction of lipid peroxidation with carbon tetrachloride in F344 rats. Chem Biol Interact 137:269-283.
    • (2001) Chem Biol Interact , vol.137 , pp. 269-283
    • Wacker, M.1    Wanek, P.2    Eder, E.3
  • 85
    • 0023930086 scopus 로고
    • Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds
    • Wangenheim J, Bolcsfoldi G. 1988. Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds. Mutagen 3:193-205.
    • (1988) Mutagen , vol.3 , pp. 193-205
    • Wangenheim, J.1    Bolcsfoldi, G.2
  • 86
    • 0037256608 scopus 로고    scopus 로고
    • Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model
    • Weber LW, Boll M, Stampfl A. 2003. Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model. Crit Rev Toxicol 33:105-136.
    • (2003) Crit Rev Toxicol , vol.33 , pp. 105-136
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 87
    • 0033802706 scopus 로고    scopus 로고
    • Differentiation of necrotic cell death with or without lysosomal activation: Application of acute liver injury models induced by carbon tetrachloride (CCL4) and dimethylnitrosamine (DMN)
    • Yasuda M, Okabe T, Itoh J, Takekoshi S, Hasegawa H, Nagata H, Osamura RY, Watanabe K. 2000. Differentiation of necrotic cell death with or without lysosomal activation: Application of acute liver injury models induced by carbon tetrachloride (CCL4) and dimethylnitrosamine (DMN). J Histochem Cytochem 48:1331-1339.
    • (2000) J Histochem Cytochem , vol.48 , pp. 1331-1339
    • Yasuda, M.1    Okabe, T.2    Itoh, J.3    Takekoshi, S.4    Hasegawa, H.5    Nagata, H.6    Osamura, R.Y.7    Watanabe, K.8


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