In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: A structure-activity relationship (QSAR) analysis of the genotoxic and cytotoxic potential

Mutagenesis

Volumn 13, Issue 2, 1998, Pages 115-126

  Tafazoli, M ^a   Baeten, A ^a   Geerlings, P ^a   Kirsch Volders, M ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; CHLORINATED HYDROCARBON; HALOGENATED HYDROCARBON; HEXACHLOROETHANE;

ARTICLE; BIOASSAY; CELL PROLIFERATION; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG MECHANISM; GEL ELECTROPHORESIS; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MUTAGENIC ACTIVITY; MUTAGENICITY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ADULT; ANIMALS; BIOTRANSFORMATION; CARCINOGENS; CELLS, CULTURED; DNA DAMAGE; ELECTROPHORESIS, AGAR GEL; HUMANS; HYDROCARBONS, CHLORINATED; LIVER; LYMPHOCYTES; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031907613     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/13.2.115     Document Type: Article

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