메뉴 건너뛰기




Volumn 22, Issue 2, 2008, Pages 375-389

Progesterone for recurrent miscarriage: truth and deceptions

Author keywords

habitual abortion; immunomodulation; pregnancy loss; progesterone; progestogen; recurrent miscarriage; treatment

Indexed keywords

CHORIONIC GONADOTROPIN; DYDROGESTERONE; FOLIC ACID; HYDROXYPROGESTERONE CAPROATE; MEDROXYPROGESTERONE; MIFEPRISTONE; PLACEBO; PROGESTERONE; VITAMIN;

EID: 39749185425     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2007.08.009     Document Type: Review
Times cited : (24)

References (100)
  • 2
    • 0029975384 scopus 로고
    • Evaluation and management of recurrent spontaneous abortion
    • Daya S. Evaluation and management of recurrent spontaneous abortion. Curr Opin Obstet Gynecol 8 (1993) 188-192
    • (1993) Curr Opin Obstet Gynecol , vol.8 , pp. 188-192
    • Daya, S.1
  • 4
    • 0031020399 scopus 로고    scopus 로고
    • Immunotherapy for unexplained recurrent spontaneous abortion
    • Daya S. Immunotherapy for unexplained recurrent spontaneous abortion. Infertil Reprod Med Clin North Am 8 (1997) 65-77
    • (1997) Infertil Reprod Med Clin North Am , vol.8 , pp. 65-77
    • Daya, S.1
  • 5
    • 0030939856 scopus 로고    scopus 로고
    • Future pregnancy outcome in unexplained recurrent first trimester miscarriage
    • Clifford K., Rai R., and Regan L. Future pregnancy outcome in unexplained recurrent first trimester miscarriage. Hum Reprod 12 (1997) 387-389
    • (1997) Hum Reprod , vol.12 , pp. 387-389
    • Clifford, K.1    Rai, R.2    Regan, L.3
  • 6
    • 20144388443 scopus 로고    scopus 로고
    • Evidence-based investigations and treatments of recurrent pregnancy loss
    • Christiansen O.B., Andersen A.M.N., Bosch E., et al. Evidence-based investigations and treatments of recurrent pregnancy loss. Fertil Steril 83 (2005) 821-839
    • (2005) Fertil Steril , vol.83 , pp. 821-839
    • Christiansen, O.B.1    Andersen, A.M.N.2    Bosch, E.3
  • 7
    • 0025708282 scopus 로고
    • Recurrent miscarriage
    • Sirrat G.M. Recurrent miscarriage. Lancet 336 (1990) 673-675
    • (1990) Lancet , vol.336 , pp. 673-675
    • Sirrat, G.M.1
  • 8
    • 39749199507 scopus 로고    scopus 로고
    • The immunology of recurrent spontaneous miscarriage
    • Taylor & Francis, London
    • Manyonda I.T. The immunology of recurrent spontaneous miscarriage. The Immunology of Human Reproduction. 1st edn (2006), Taylor & Francis, London 59-77
    • (2006) The Immunology of Human Reproduction. 1st edn , pp. 59-77
    • Manyonda, I.T.1
  • 9
    • 0023190204 scopus 로고
    • Prognosis of subsequent pregnancies after recurrent spontaneous abortion in first trimester
    • Vlaanderen W., and Treffers P.K. Prognosis of subsequent pregnancies after recurrent spontaneous abortion in first trimester. BMJ 295 (1987) 92-93
    • (1987) BMJ , vol.295 , pp. 92-93
    • Vlaanderen, W.1    Treffers, P.K.2
  • 10
    • 33745496821 scopus 로고    scopus 로고
    • A combination treatment of prednisone, aspirin, folate, and progesterone in women with idiopathic recurrent miscarriage: a matched-pair study
    • Tempfer C.B., Kurz C., Bentz E.K., et al. A combination treatment of prednisone, aspirin, folate, and progesterone in women with idiopathic recurrent miscarriage: a matched-pair study. Fertil Steril 86 (2006) 145-148
    • (2006) Fertil Steril , vol.86 , pp. 145-148
    • Tempfer, C.B.1    Kurz, C.2    Bentz, E.K.3
  • 11
    • 0019319222 scopus 로고
    • Pregnancy order and fetal loss
    • Roman E.A., Alberman E., and Pharoah P.O. Pregnancy order and fetal loss. BMJ 280 (1980) 715
    • (1980) BMJ , vol.280 , pp. 715
    • Roman, E.A.1    Alberman, E.2    Pharoah, P.O.3
  • 13
    • 33646442797 scopus 로고    scopus 로고
    • Management of recurrent early pregnancy loss
    • Stephenson M.D. Management of recurrent early pregnancy loss. J Reprod Med 51 (2006) 303-310
    • (2006) J Reprod Med , vol.51 , pp. 303-310
    • Stephenson, M.D.1
  • 15
    • 0037264773 scopus 로고    scopus 로고
    • Immunotherapy for recurrent miscarriage
    • CD000112
    • Scott J.R. Immunotherapy for recurrent miscarriage. Cochrane Database Syst Rev 1 (2003) CD000112
    • (2003) Cochrane Database Syst Rev , vol.1
    • Scott, J.R.1
  • 16
    • 0033772697 scopus 로고    scopus 로고
    • Recurrent miscarriage - an aspirin a day?
    • Rai R., Backos M., Baxter N., et al. Recurrent miscarriage - an aspirin a day?. Hum Reprod 15 (2000) 2220-2223
    • (2000) Hum Reprod , vol.15 , pp. 2220-2223
    • Rai, R.1    Backos, M.2    Baxter, N.3
  • 17
    • 31144467556 scopus 로고    scopus 로고
    • Endocrinology of recurrent pregnancy loss
    • Arredondo F., and Noble L.S. Endocrinology of recurrent pregnancy loss. Semin Reprod Med 24 (2006) 33-39
    • (2006) Semin Reprod Med , vol.24 , pp. 33-39
    • Arredondo, F.1    Noble, L.S.2
  • 19
    • 22944457834 scopus 로고    scopus 로고
    • The endocrinological basis of recurrent miscarriage
    • Potdar N., and Konje J.C. The endocrinological basis of recurrent miscarriage. Curr Opin Obstet Gynecol 17 (2005) 424-428
    • (2005) Curr Opin Obstet Gynecol , vol.17 , pp. 424-428
    • Potdar, N.1    Konje, J.C.2
  • 20
    • 0015924481 scopus 로고
    • Effects of lutectomy and progesterone replacement in early pregnant patients
    • Csapo A.I., Pilkkinen M.O., and Wiest W.G. Effects of lutectomy and progesterone replacement in early pregnant patients. Am J Obstet Gynecol 115 (1973) 759-764
    • (1973) Am J Obstet Gynecol , vol.115 , pp. 759-764
    • Csapo, A.I.1    Pilkkinen, M.O.2    Wiest, W.G.3
  • 21
    • 0018293688 scopus 로고
    • Corpus luteum dysfunction: serum progesterone levels in diagnosis and assessment of therapy for recurrent and threatened abortion
    • Hensleigh P.A., and Fainstat T. Corpus luteum dysfunction: serum progesterone levels in diagnosis and assessment of therapy for recurrent and threatened abortion. Fertil Steril 32 (1979) 715-719
    • (1979) Fertil Steril , vol.32 , pp. 715-719
    • Hensleigh, P.A.1    Fainstat, T.2
  • 22
    • 0021810893 scopus 로고
    • The late luteal phase in infertile women: comparison of simultaneous endometrial biopsy and progesterone levels
    • Cumming D.C., Honore L.H., Scott J.Z., et al. The late luteal phase in infertile women: comparison of simultaneous endometrial biopsy and progesterone levels. Fertil Steril 43 (1985) 715-719
    • (1985) Fertil Steril , vol.43 , pp. 715-719
    • Cumming, D.C.1    Honore, L.H.2    Scott, J.Z.3
  • 24
    • 0028299718 scopus 로고
    • Issues in the etiology of recurrent spontaneous abortion
    • Daya S. Issues in the etiology of recurrent spontaneous abortion. Curr Opin Obstet Gynecol 6 (1994) 153-159
    • (1994) Curr Opin Obstet Gynecol , vol.6 , pp. 153-159
    • Daya, S.1
  • 25
    • 0018865168 scopus 로고
    • Myometrial inhibiting activity of relaxin containing extracts of human corpora lutea of pregnancy
    • Szlachter N., O'Byrne E., Goldsmith L., et al. Myometrial inhibiting activity of relaxin containing extracts of human corpora lutea of pregnancy. Am J Obstet Gynecol 136 (1980) 584-586
    • (1980) Am J Obstet Gynecol , vol.136 , pp. 584-586
    • Szlachter, N.1    O'Byrne, E.2    Goldsmith, L.3
  • 26
    • 0031686025 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase messenger ribonucleic acid expression in pregnant rat uterus
    • Dong Y.L., Fang L., Gangula P.R.R., et al. Regulation of inducible nitric oxide synthase messenger ribonucleic acid expression in pregnant rat uterus. Biol Reprod 59 (1998) 933-940
    • (1998) Biol Reprod , vol.59 , pp. 933-940
    • Dong, Y.L.1    Fang, L.2    Gangula, P.R.R.3
  • 27
    • 33748890173 scopus 로고    scopus 로고
    • Effects of dydrogesterone and of its stable metabolite, 20-α-dihydrogesterone, on nitric oxide synthesis in human endothelial cells
    • Simoncini T., Caruso A., Giretti M.S., et al. Effects of dydrogesterone and of its stable metabolite, 20-α-dihydrogesterone, on nitric oxide synthesis in human endothelial cells. Fertil Steril 86 Suppl 3 (2006) 1235-1242
    • (2006) Fertil Steril , vol.86 , Issue.SUPPL. 3 , pp. 1235-1242
    • Simoncini, T.1    Caruso, A.2    Giretti, M.S.3
  • 28
    • 0024553210 scopus 로고
    • A meta-analysis of randomized control trials of progestational agents in pregnancy
    • Goldstein P., Berrier J., Rosen S., et al. A meta-analysis of randomized control trials of progestational agents in pregnancy. Br J Obstet Gynaecol 96 (1989) 265-274
    • (1989) Br J Obstet Gynaecol , vol.96 , pp. 265-274
    • Goldstein, P.1    Berrier, J.2    Rosen, S.3
  • 29
    • 0024605503 scopus 로고
    • Efficacy of progesterone support for pregnancy in women with recurrent miscarriage. A meta-analysis of controlled trials
    • Daya S. Efficacy of progesterone support for pregnancy in women with recurrent miscarriage. A meta-analysis of controlled trials. Br J Obstet Gynaecol 96 (1989) 257-260
    • (1989) Br J Obstet Gynaecol , vol.96 , pp. 257-260
    • Daya, S.1
  • 31
    • 28044437186 scopus 로고    scopus 로고
    • Dydrogesterone in the reduction of recurrent spontaneous abortion
    • El-Zibdeh M.Y. Dydrogesterone in the reduction of recurrent spontaneous abortion. J Steroid Biochem Mol Biol 97 (2005) 431-434
    • (2005) J Steroid Biochem Mol Biol , vol.97 , pp. 431-434
    • El-Zibdeh, M.Y.1
  • 32
    • 28044432350 scopus 로고    scopus 로고
    • The role of dydrogesterone in recurrent (habitual) abortion
    • Gruber C.J., and Huber J.C. The role of dydrogesterone in recurrent (habitual) abortion. J Ster Biochem Mol Biol 97 (2005) 426-430
    • (2005) J Ster Biochem Mol Biol , vol.97 , pp. 426-430
    • Gruber, C.J.1    Huber, J.C.2
  • 34
    • 0023260544 scopus 로고
    • Progesterone therapy to decrease first-trimester spontaneous abortions in previous aborters
    • Check J.H., Chase J., Nowroozi K., et al. Progesterone therapy to decrease first-trimester spontaneous abortions in previous aborters. Int J Fertil 33 (1987) 192-199
    • (1987) Int J Fertil , vol.33 , pp. 192-199
    • Check, J.H.1    Chase, J.2    Nowroozi, K.3
  • 35
    • 0032968661 scopus 로고    scopus 로고
    • Genes associated with embryonic attachment and implantation and the role of progesterone
    • Giudice L.C. Genes associated with embryonic attachment and implantation and the role of progesterone. J Reprod Med 44 (1999) 165-171
    • (1999) J Reprod Med , vol.44 , pp. 165-171
    • Giudice, L.C.1
  • 36
    • 0017620255 scopus 로고
    • Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant?
    • Siiteri P.K., Febres F., and Clemens L.E. Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant?. Ann NY Acac Sci 286 (1977) 384-397
    • (1977) Ann NY Acac Sci , vol.286 , pp. 384-397
    • Siiteri, P.K.1    Febres, F.2    Clemens, L.E.3
  • 37
    • 0024836888 scopus 로고
    • The cytokine basis for cross-talk between the maternal immune and reproductive systems
    • Wegmann T.G. The cytokine basis for cross-talk between the maternal immune and reproductive systems. Curr Opin Immunol 2 (1990) 765-769
    • (1990) Curr Opin Immunol , vol.2 , pp. 765-769
    • Wegmann, T.G.1
  • 38
    • 0033869345 scopus 로고    scopus 로고
    • Cytokine network at the feto-maternal interface
    • Saito S. Cytokine network at the feto-maternal interface. J Reprod Immunol 47 (2000) 87-103
    • (2000) J Reprod Immunol , vol.47 , pp. 87-103
    • Saito, S.1
  • 39
    • 0034839487 scopus 로고    scopus 로고
    • Unexplained sporadic and recurrent miscarriage in the new millenium: a critical analysis of immune mechanisms and treatments
    • Clark D.A., Coulam C.B., Daya S., et al. Unexplained sporadic and recurrent miscarriage in the new millenium: a critical analysis of immune mechanisms and treatments. Hum Reprod Update 7 (2001) 501-511
    • (2001) Hum Reprod Update , vol.7 , pp. 501-511
    • Clark, D.A.1    Coulam, C.B.2    Daya, S.3
  • 40
    • 0033014385 scopus 로고    scopus 로고
    • Why did your mother reject you? Immunogenetic determinants of the response to environmental selective pressure expressed at uterine level
    • Clark D.A., Arck P.C., and Chaouat G. Why did your mother reject you? Immunogenetic determinants of the response to environmental selective pressure expressed at uterine level. Am J Reprod Immunol 41 (1999) 5-22
    • (1999) Am J Reprod Immunol , vol.41 , pp. 5-22
    • Clark, D.A.1    Arck, P.C.2    Chaouat, G.3
  • 41
    • 0029856002 scopus 로고    scopus 로고
    • A fresh look at the causes and treatment of recurrent miscarriage, especially its immunological aspects
    • Christiansen O.B. A fresh look at the causes and treatment of recurrent miscarriage, especially its immunological aspects. Hum Reprod Update 2 (1996) 271-293
    • (1996) Hum Reprod Update , vol.2 , pp. 271-293
    • Christiansen, O.B.1
  • 42
    • 0036858934 scopus 로고    scopus 로고
    • Immunological relationship between the mother and the fetus
    • Szekeres-Bartho J. Immunological relationship between the mother and the fetus. Int Rev Immunol 21 (2002) 471-496
    • (2002) Int Rev Immunol , vol.21 , pp. 471-496
    • Szekeres-Bartho, J.1
  • 43
    • 0031862739 scopus 로고    scopus 로고
    • Early recognition of pregnancy by the maternal immune system
    • Kelemen K., Paldi A., Tinneberg H., et al. Early recognition of pregnancy by the maternal immune system. Am J Reprod Immunol 39 (1998) 351-355
    • (1998) Am J Reprod Immunol , vol.39 , pp. 351-355
    • Kelemen, K.1    Paldi, A.2    Tinneberg, H.3
  • 44
    • 0027207375 scopus 로고
    • Bidirectional cytokine interactions in maternal-fetal relationship: is successful pregnancy a Th2 phenomenon?
    • Wegmann T.G., Lin H., Guilbert L., et al. Bidirectional cytokine interactions in maternal-fetal relationship: is successful pregnancy a Th2 phenomenon?. Immunol Today 14 (1993) 353-356
    • (1993) Immunol Today , vol.14 , pp. 353-356
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3
  • 45
    • 0034794829 scopus 로고    scopus 로고
    • Th1 and Th2 cytokine profiles in recurrent aborters with successful pregnancy and with subsequent abortions
    • Makhseed M., Raghupathy R., Azizieh F., et al. Th1 and Th2 cytokine profiles in recurrent aborters with successful pregnancy and with subsequent abortions. Hum Reprod 16 (2001) 2219-2226
    • (2001) Hum Reprod , vol.16 , pp. 2219-2226
    • Makhseed, M.1    Raghupathy, R.2    Azizieh, F.3
  • 46
    • 0030959718 scopus 로고    scopus 로고
    • Th1-type immunity is incompatible with successful pregnancy
    • Raghupathy R. Th1-type immunity is incompatible with successful pregnancy. Immunol Today 18 (1997) 478-482
    • (1997) Immunol Today , vol.18 , pp. 478-482
    • Raghupathy, R.1
  • 47
    • 0037951573 scopus 로고    scopus 로고
    • Th1 cytokines and the prothrombinase fgl2 in stress-triggered and inflammatory abortion
    • Knackstedt M.K., Zenclussen A.C., Hertwig K., et al. Th1 cytokines and the prothrombinase fgl2 in stress-triggered and inflammatory abortion. Am J Reprod Immunol 49 (2003) 210-220
    • (2003) Am J Reprod Immunol , vol.49 , pp. 210-220
    • Knackstedt, M.K.1    Zenclussen, A.C.2    Hertwig, K.3
  • 48
    • 0032988305 scopus 로고    scopus 로고
    • The emerging role of immunoregulation of fibrinogen-related procoagulant Fgl2 in the success or spontaneous abortion of early pregnancy in mice and humans
    • Clark D.A., Ding J.W., Chaouat G., et al. The emerging role of immunoregulation of fibrinogen-related procoagulant Fgl2 in the success or spontaneous abortion of early pregnancy in mice and humans. Am J Reprod Immunol 42 (1999) 37-42
    • (1999) Am J Reprod Immunol , vol.42 , pp. 37-42
    • Clark, D.A.1    Ding, J.W.2    Chaouat, G.3
  • 49
    • 4644277662 scopus 로고    scopus 로고
    • Progesterone supplement in pregnancy: an immunologic therapy?
    • Ragusa A., de Carolis C., dal Lago A., et al. Progesterone supplement in pregnancy: an immunologic therapy?. Lupus 13 (2004) 639-642
    • (2004) Lupus , vol.13 , pp. 639-642
    • Ragusa, A.1    de Carolis, C.2    dal Lago, A.3
  • 50
    • 0037386353 scopus 로고    scopus 로고
    • Increased T helper 1 cytokine responses by circulating T cells are present in women with recurrent pregnancy losses and in infertile women with multiple implantation failures after IVF
    • Kwak-Kim J.Y., Chung-Bang H.S., Ng S.C., et al. Increased T helper 1 cytokine responses by circulating T cells are present in women with recurrent pregnancy losses and in infertile women with multiple implantation failures after IVF. Hum Reprod 18 (2003) 767-773
    • (2003) Hum Reprod , vol.18 , pp. 767-773
    • Kwak-Kim, J.Y.1    Chung-Bang, H.S.2    Ng, S.C.3
  • 51
    • 0034008633 scopus 로고    scopus 로고
    • Cytokine production by maternal lymphoctes during normal human pregnancy and in unexplained recurrent spontaneous abortion
    • Raghupathy R., Makhseed M., Azizieh F., et al. Cytokine production by maternal lymphoctes during normal human pregnancy and in unexplained recurrent spontaneous abortion. Hum Reprod 15 (2000) 713-718
    • (2000) Hum Reprod , vol.15 , pp. 713-718
    • Raghupathy, R.1    Makhseed, M.2    Azizieh, F.3
  • 52
    • 0042669785 scopus 로고    scopus 로고
    • Th1/Th2 balance in preeclampsia
    • Saito S., and Sakai M. Th1/Th2 balance in preeclampsia. Reprod Immunol 59 (2003) 161-173
    • (2003) Reprod Immunol , vol.59 , pp. 161-173
    • Saito, S.1    Sakai, M.2
  • 53
    • 0038363980 scopus 로고    scopus 로고
    • Pro-inflammatory maternal cytokine profile in preterm delivery
    • Makhseed M., Raghupathy R., El-Shazly F., et al. Pro-inflammatory maternal cytokine profile in preterm delivery. Am J Reprod Immunol 49 (2003) 308-318
    • (2003) Am J Reprod Immunol , vol.49 , pp. 308-318
    • Makhseed, M.1    Raghupathy, R.2    El-Shazly, F.3
  • 54
    • 4644354630 scopus 로고    scopus 로고
    • Cytokines in recurrent miscarriage
    • Carp H. Cytokines in recurrent miscarriage. Lupus 13 (2004) 630-634
    • (2004) Lupus , vol.13 , pp. 630-634
    • Carp, H.1
  • 55
    • 0028875653 scopus 로고
    • Decidual natural killer cytotoxity decreased in normal pregnancy but not in anembryonic pregnancy and recurrent spontaneous abortion
    • Chao K.H., Yang Y.S., Ho H.N., et al. Decidual natural killer cytotoxity decreased in normal pregnancy but not in anembryonic pregnancy and recurrent spontaneous abortion. Am J Reprod Immunol 34 (1995) 274-280
    • (1995) Am J Reprod Immunol , vol.34 , pp. 274-280
    • Chao, K.H.1    Yang, Y.S.2    Ho, H.N.3
  • 56
    • 0035004533 scopus 로고    scopus 로고
    • Status of peripheral blood natural killer cells in women with recurrent spontaneous abortions and infertility of unknown aetiology
    • Ntrivalas E.I., Kwak-Kim J.Y.H., Gilman-Sachs A., et al. Status of peripheral blood natural killer cells in women with recurrent spontaneous abortions and infertility of unknown aetiology. Hum Reprod 16 (2001) 855-861
    • (2001) Hum Reprod , vol.16 , pp. 855-861
    • Ntrivalas, E.I.1    Kwak-Kim, J.Y.H.2    Gilman-Sachs, A.3
  • 57
    • 0029004576 scopus 로고
    • Preconceptional natural killer cell activity as a predictor of miscarriage
    • Aoki K., Kajiura S., Matsumoto Y., et al. Preconceptional natural killer cell activity as a predictor of miscarriage. Lancet 345 (1995) 1340-1342
    • (1995) Lancet , vol.345 , pp. 1340-1342
    • Aoki, K.1    Kajiura, S.2    Matsumoto, Y.3
  • 58
    • 0347986537 scopus 로고    scopus 로고
    • A new role for natural killer cells, interleukin (IL)-12, and IL-18 in repeated implantation failures after in vitro fertilization
    • Ledee-Bataille N., Dubanchet S., Coulomb-L'hermine A., et al. A new role for natural killer cells, interleukin (IL)-12, and IL-18 in repeated implantation failures after in vitro fertilization. Fertil Steril 81 (2004) 59-65
    • (2004) Fertil Steril , vol.81 , pp. 59-65
    • Ledee-Bataille, N.1    Dubanchet, S.2    Coulomb-L'hermine, A.3
  • 59
    • 0032727379 scopus 로고    scopus 로고
    • Endometrial CD56+ natural killer cells in women with recurrent miscarriage: a histomorphometric study
    • Clifford K., Flanagan A.M., and Regan L. Endometrial CD56+ natural killer cells in women with recurrent miscarriage: a histomorphometric study. Hum Reprod 14 (1999) 2727-2730
    • (1999) Hum Reprod , vol.14 , pp. 2727-2730
    • Clifford, K.1    Flanagan, A.M.2    Regan, L.3
  • 60
    • 0035011012 scopus 로고    scopus 로고
    • Leukocyte activation in the decidua of chromosomally normal and abnormal fetuses from women with recurrent abortion
    • Quack K.C., Vassiliadou N., Pudney J., et al. Leukocyte activation in the decidua of chromosomally normal and abnormal fetuses from women with recurrent abortion. Hum Reprod 16 (2001) 949-955
    • (2001) Hum Reprod , vol.16 , pp. 949-955
    • Quack, K.C.1    Vassiliadou, N.2    Pudney, J.3
  • 62
    • 0028572541 scopus 로고
    • Cytotoxicity of tumor necrosis factor-alpha and gamma-interferon against primary human placental trophoblast
    • Yui J., Garcia-Lloret M., Wegmann T.G., et al. Cytotoxicity of tumor necrosis factor-alpha and gamma-interferon against primary human placental trophoblast. Placenta 15 (1994) 819-835
    • (1994) Placenta , vol.15 , pp. 819-835
    • Yui, J.1    Garcia-Lloret, M.2    Wegmann, T.G.3
  • 63
    • 0025776877 scopus 로고
    • IgG asymmetric molecules with antipaternal activity isolated from sera and placenta of pregnant human
    • Malan Borel I., Gentile T., Angelucci J., et al. IgG asymmetric molecules with antipaternal activity isolated from sera and placenta of pregnant human. J Reprod Immunol 20 (1991) 129-140
    • (1991) J Reprod Immunol , vol.20 , pp. 129-140
    • Malan Borel, I.1    Gentile, T.2    Angelucci, J.3
  • 64
    • 0033957902 scopus 로고    scopus 로고
    • Alterations in humoral immune responses associated with recurrent pregnancy loss
    • Eblen A.C., Gercel-Taylor C., Shields L.B.E., et al. Alterations in humoral immune responses associated with recurrent pregnancy loss. Fertil Steril 73 (2000) 305-313
    • (2000) Fertil Steril , vol.73 , pp. 305-313
    • Eblen, A.C.1    Gercel-Taylor, C.2    Shields, L.B.E.3
  • 65
    • 0024456567 scopus 로고
    • Progesterone receptors in lymphocytes of liver-transplanted and transfused patients
    • Szekeres-Bartho J., Weill B.J., Mike G., et al. Progesterone receptors in lymphocytes of liver-transplanted and transfused patients. Immunol Lett 22 (1989) 259-261
    • (1989) Immunol Lett , vol.22 , pp. 259-261
    • Szekeres-Bartho, J.1    Weill, B.J.2    Mike, G.3
  • 66
    • 0025117740 scopus 로고
    • Reactivity of lymphocytes to a progesterone-specific monoclonal antibody
    • Szekeres-Bartho J., Szekeres G., Debre P., et al. Reactivity of lymphocytes to a progesterone-specific monoclonal antibody. Cell Immunol 125 (1990) 273-283
    • (1990) Cell Immunol , vol.125 , pp. 273-283
    • Szekeres-Bartho, J.1    Szekeres, G.2    Debre, P.3
  • 68
    • 0028804013 scopus 로고
    • The expression of a progesterone-induced immunomodulatory protein in pregnancy lymphocytes
    • Szekeres-Bartho J., Faust Z., and Varga P. The expression of a progesterone-induced immunomodulatory protein in pregnancy lymphocytes. Am J Reprod Immunol 34 (1995) 342-348
    • (1995) Am J Reprod Immunol , vol.34 , pp. 342-348
    • Szekeres-Bartho, J.1    Faust, Z.2    Varga, P.3
  • 69
    • 0024465136 scopus 로고
    • ELISA test for detecting a progesterone-induced immunological factor in pregnancy serum
    • Szekeres-Bartho J., Varga P., and Petjsik B. ELISA test for detecting a progesterone-induced immunological factor in pregnancy serum. J Reprod Immunol 16 (1989) 19-29
    • (1989) J Reprod Immunol , vol.16 , pp. 19-29
    • Szekeres-Bartho, J.1    Varga, P.2    Petjsik, B.3
  • 70
    • 15844365871 scopus 로고    scopus 로고
    • The impact of dydrogesterone supplementation on hormonal profile and progesterone-induced blocking factor concentrations in women with threatened abortion
    • Kalinka J., and Szekeres-Bartho J. The impact of dydrogesterone supplementation on hormonal profile and progesterone-induced blocking factor concentrations in women with threatened abortion. Am J Reprod Immunol 53 (2005) 166-171
    • (2005) Am J Reprod Immunol , vol.53 , pp. 166-171
    • Kalinka, J.1    Szekeres-Bartho, J.2
  • 71
    • 0034101220 scopus 로고    scopus 로고
    • Progesterone inhibits in vitro embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss
    • Choi B.C., Polgar K., Xiao L., et al. Progesterone inhibits in vitro embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss. Hum Reprod 15 (2000) 46-59
    • (2000) Hum Reprod , vol.15 , pp. 46-59
    • Choi, B.C.1    Polgar, K.2    Xiao, L.3
  • 72
    • 0029036806 scopus 로고
    • Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones
    • Piccinni M.P., Giudizi M.G., Biagotti R., et al. Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. J Immunol 155 (1995) 128-133
    • (1995) J Immunol , vol.155 , pp. 128-133
    • Piccinni, M.P.1    Giudizi, M.G.2    Biagotti, R.3
  • 73
    • 0036075216 scopus 로고    scopus 로고
    • Th1 and Th2 cytokine profiles in recurrent aborters may merely reflect progesterone status
    • Check J.H. Th1 and Th2 cytokine profiles in recurrent aborters may merely reflect progesterone status. Hum Reprod 17 (2002) 1669-1674
    • (2002) Hum Reprod , vol.17 , pp. 1669-1674
    • Check, J.H.1
  • 74
    • 15844395561 scopus 로고    scopus 로고
    • Modulation of cytokine production by dydrogesterone in lymphocytes from women with recurrent miscarriage
    • Raghupathy R., Al Mutawa E., Makhseed M., et al. Modulation of cytokine production by dydrogesterone in lymphocytes from women with recurrent miscarriage. Br J Obstet Gynaecol 112 (2005) 1096-1101
    • (2005) Br J Obstet Gynaecol , vol.112 , pp. 1096-1101
    • Raghupathy, R.1    Al Mutawa, E.2    Makhseed, M.3
  • 75
    • 2442450438 scopus 로고    scopus 로고
    • + cells abolishes the pregnancy protective effect of progesterone substitution with dydrogesterone in mice by altering the Th1/Th2 cytokine profile
    • + cells abolishes the pregnancy protective effect of progesterone substitution with dydrogesterone in mice by altering the Th1/Th2 cytokine profile. J Immunol 172 (2004) 5893-5899
    • (2004) J Immunol , vol.172 , pp. 5893-5899
    • Blois, S.M.1    Joachim, R.2    Kandil, J.3
  • 76
    • 0031149758 scopus 로고    scopus 로고
    • The anti-abortive effect of PIBF in mice is manifested by modulating NK activity
    • Szekeres-Bartho J., Par G., Dombay G.Y., et al. The anti-abortive effect of PIBF in mice is manifested by modulating NK activity. Cell Immunol 177 (1997) 194-199
    • (1997) Cell Immunol , vol.177 , pp. 194-199
    • Szekeres-Bartho, J.1    Par, G.2    Dombay, G.Y.3
  • 77
    • 0033170413 scopus 로고    scopus 로고
    • Progesterone induced blocking factor inhibits degranulation of NK cells
    • Faust Z., Laskarin G., Rukavina D., et al. Progesterone induced blocking factor inhibits degranulation of NK cells. Am J Reprod Immunol 42 (1999) 71-75
    • (1999) Am J Reprod Immunol , vol.42 , pp. 71-75
    • Faust, Z.1    Laskarin, G.2    Rukavina, D.3
  • 78
    • 0030069904 scopus 로고    scopus 로고
    • A progesterone-induced protein increases the synthesis of asymmetric antibodies
    • Kelemen K., Bognar I., Paal M., et al. A progesterone-induced protein increases the synthesis of asymmetric antibodies. Cell Immunol 167 (1996) 129-134
    • (1996) Cell Immunol , vol.167 , pp. 129-134
    • Kelemen, K.1    Bognar, I.2    Paal, M.3
  • 79
    • 6344284675 scopus 로고    scopus 로고
    • Urinary progesterone-induced blocking factor concentration is related to pregnancy outcome
    • Polgar B., Nagy E., Miko E., et al. Urinary progesterone-induced blocking factor concentration is related to pregnancy outcome. Biol Reprod 71 (2004) 1699-1705
    • (2004) Biol Reprod , vol.71 , pp. 1699-1705
    • Polgar, B.1    Nagy, E.2    Miko, E.3
  • 80
    • 22244448087 scopus 로고    scopus 로고
    • Changes in progesterone-induced-blocking factor expression rates following mifepristone administration in termination of pregnancy at 5 to 8 weeks
    • Salomon L.J., Rozenberg P., Szekeres-Bartho J., et al. Changes in progesterone-induced-blocking factor expression rates following mifepristone administration in termination of pregnancy at 5 to 8 weeks. J Matern Fetal Neonatal Med 17 (2005) 353-356
    • (2005) J Matern Fetal Neonatal Med , vol.17 , pp. 353-356
    • Salomon, L.J.1    Rozenberg, P.2    Szekeres-Bartho, J.3
  • 81
    • 0345735760 scopus 로고    scopus 로고
    • The progesterone derivative dydrogesterone abrogates murine stress-triggered abortion by inducing a Th2 biased local immune response
    • Joachim R., Zenclussen A.C., Polgar B., et al. The progesterone derivative dydrogesterone abrogates murine stress-triggered abortion by inducing a Th2 biased local immune response. Steroids 68 (2003) 931-940
    • (2003) Steroids , vol.68 , pp. 931-940
    • Joachim, R.1    Zenclussen, A.C.2    Polgar, B.3
  • 82
    • 0036258085 scopus 로고    scopus 로고
    • A brief review of recent data on some cytokine expressions at the materno-foetal interface that might challenge the classical Th-1/Th-2 dichotomy
    • Chaouat G., Zourbas S., Ostojic S., et al. A brief review of recent data on some cytokine expressions at the materno-foetal interface that might challenge the classical Th-1/Th-2 dichotomy. J Reprod Immunol 53 (2002) 241-256
    • (2002) J Reprod Immunol , vol.53 , pp. 241-256
    • Chaouat, G.1    Zourbas, S.2    Ostojic, S.3
  • 83
    • 0037558325 scopus 로고
    • Progesterone implantation in habitual abortion
    • Swyer G.I.M., and Daley D. Progesterone implantation in habitual abortion. BMJ 1 (1953) 1073-1086
    • (1953) BMJ , vol.1 , pp. 1073-1086
    • Swyer, G.I.M.1    Daley, D.2
  • 84
    • 0347186257 scopus 로고
    • Isopregnenone (Duphaston): a new progestational agent
    • Backer Jr. M.H. Isopregnenone (Duphaston): a new progestational agent. Obstet Gynecol 19 (1962) 724-729
    • (1962) Obstet Gynecol , vol.19 , pp. 724-729
    • Backer Jr., M.H.1
  • 85
    • 0010039024 scopus 로고
    • Habitual abortion: a controlled clinical study of progestational therapy
    • Le Vine L. Habitual abortion: a controlled clinical study of progestational therapy. West J Surg 72 (1964) 30-36
    • (1964) West J Surg , vol.72 , pp. 30-36
    • Le Vine, L.1
  • 86
    • 0037896277 scopus 로고
    • Double-blind trial of a progestin in habitual abortion
    • Goldzieher J.W. Double-blind trial of a progestin in habitual abortion. JAMA 188 (1964) 651-654
    • (1964) JAMA , vol.188 , pp. 651-654
    • Goldzieher, J.W.1
  • 87
    • 0013797647 scopus 로고
    • Apropos of the use of dydrogesterone in gynecology and obstetrics; clinical experience
    • Gelle P., and Schaeffer P. Apropos of the use of dydrogesterone in gynecology and obstetrics; clinical experience. Bull Fed Soc Gynecol Obstet Lang Fr 17 (1965) 369-370
    • (1965) Bull Fed Soc Gynecol Obstet Lang Fr , vol.17 , pp. 369-370
    • Gelle, P.1    Schaeffer, P.2
  • 88
    • 17344389458 scopus 로고
    • Utilization of 6-dehydro-retroprogesterone in obstetrics: indications; results
    • Jamain M., and Grenet C. Utilization of 6-dehydro-retroprogesterone in obstetrics: indications; results. Bull Fed Soc Gynecol Obstet Lang Fr 21 (1969) 26-31
    • (1969) Bull Fed Soc Gynecol Obstet Lang Fr , vol.21 , pp. 26-31
    • Jamain, M.1    Grenet, C.2
  • 89
    • 0014729169 scopus 로고
    • Dydrogesterone in treatment of hypohormonal pregnancy
    • Radulesco J.C. Dydrogesterone in treatment of hypohormonal pregnancy. Mars Med 107 (1970) 191-196
    • (1970) Mars Med , vol.107 , pp. 191-196
    • Radulesco, J.C.1
  • 90
    • 28044436748 scopus 로고    scopus 로고
    • Dydrogesterone in threatened abortion: pregnancy outcome
    • Omar M.H., Mashita M.K., Lim P.S., et al. Dydrogesterone in threatened abortion: pregnancy outcome. J Steroid Biochem Mol Biol 97 (2005) 421-425
    • (2005) J Steroid Biochem Mol Biol , vol.97 , pp. 421-425
    • Omar, M.H.1    Mashita, M.K.2    Lim, P.S.3
  • 91
  • 93
    • 0031993633 scopus 로고    scopus 로고
    • Guidelines for practitioners. Recurrent miscarriage: principles of management
    • Li T.C. Guidelines for practitioners. Recurrent miscarriage: principles of management. Hum Reprod 13 (1998) 478-482
    • (1998) Hum Reprod , vol.13 , pp. 478-482
    • Li, T.C.1
  • 94
    • 28844493181 scopus 로고    scopus 로고
    • Oral dydrogesterone treatment during the first trimester of pregnancy: the Prevention of Miscarriage Study (PROMIS). A double-blind, prospectively randomized, placebo-controlled, parallel group trial
    • Walch K., Hefler L., and Nagele F. Oral dydrogesterone treatment during the first trimester of pregnancy: the Prevention of Miscarriage Study (PROMIS). A double-blind, prospectively randomized, placebo-controlled, parallel group trial. J Matern Fetal Neonatal Med 18 (2005) 265-269
    • (2005) J Matern Fetal Neonatal Med , vol.18 , pp. 265-269
    • Walch, K.1    Hefler, L.2    Nagele, F.3
  • 95
    • 0021882431 scopus 로고
    • Congenital malformations among offspring exposed in utero to progestins. Olmsted Country, Minnesota 1936-1974
    • Resseguie L.J., Hick J.F., Bruen J.A., et al. Congenital malformations among offspring exposed in utero to progestins. Olmsted Country, Minnesota 1936-1974. Fertil Steril 43 (1985) 514-518
    • (1985) Fertil Steril , vol.43 , pp. 514-518
    • Resseguie, L.J.1    Hick, J.F.2    Bruen, J.A.3
  • 96
    • 0031925382 scopus 로고    scopus 로고
    • FISH preimplantation diagnosis of chromosome aneuploidy in recurrent pregnancy wastage
    • Vidal F., Gimenez C., Rubio C., et al. FISH preimplantation diagnosis of chromosome aneuploidy in recurrent pregnancy wastage. J Assist Reprod Genet 15 (1998) 310-313
    • (1998) J Assist Reprod Genet , vol.15 , pp. 310-313
    • Vidal, F.1    Gimenez, C.2    Rubio, C.3
  • 97
    • 0036182393 scopus 로고    scopus 로고
    • Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study
    • Stephenson M.D., Awartani K.A., and Robinson W.P. Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study. Hum Reprod 17 (2002) 446-451
    • (2002) Hum Reprod , vol.17 , pp. 446-451
    • Stephenson, M.D.1    Awartani, K.A.2    Robinson, W.P.3
  • 98
    • 0027313539 scopus 로고
    • Placental and decidual histology in spontaneous abortion: detailed description and correlations with chromosome number
    • Salafia C., Maier D., Vogel C., et al. Placental and decidual histology in spontaneous abortion: detailed description and correlations with chromosome number. Obstet Gynecol 82 (1993) 295-303
    • (1993) Obstet Gynecol , vol.82 , pp. 295-303
    • Salafia, C.1    Maier, D.2    Vogel, C.3
  • 99
    • 35148823435 scopus 로고    scopus 로고
    • Progesterone for the prevention of preterm birth: a critical evaluation of evidence
    • Coomarasamy A., Thangaratinam S., Gee H., et al. Progesterone for the prevention of preterm birth: a critical evaluation of evidence. Eur J Obstet Gynecol Reprod Biol 129 (2006) 111-118
    • (2006) Eur J Obstet Gynecol Reprod Biol , vol.129 , pp. 111-118
    • Coomarasamy, A.1    Thangaratinam, S.2    Gee, H.3
  • 100
    • 84921704708 scopus 로고    scopus 로고
    • Luteal phase support in assisted reproduction cycles
    • CD004830
    • Daya S., and Gunby J. Luteal phase support in assisted reproduction cycles. Cochrane Database Syst Rev 3 (2004) CD004830
    • (2004) Cochrane Database Syst Rev , vol.3
    • Daya, S.1    Gunby, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.