Cytokine network at the feto-maternal interface

Journal of Reproductive Immunology

Volumn 47, Issue 2, 2000, Pages 87-103

  Saito, Shigeru ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cytokine; Endocrine; Immune function; Pregnancy; Trophoblast

Indexed keywords

CD69 ANTIGEN; CHORIONIC GONADOTROPIN; CYTOKINE; HLA DR ANTIGEN; INTERLEUKIN 4; INTERLEUKIN 6; PROGESTERONE;

ENDOCRINE SYSTEM; FETOPLACENTAL UNIT; FIRST TRIMESTER PREGNANCY; HUMAN; IMMUNE SYSTEM; LYMPHOCYTE ACTIVATION; NIDATION; PREGNANCY; PRIORITY JOURNAL; REVIEW; TROPHOBLAST;

CYTOKINES; DECIDUA; EMBRYO IMPLANTATION; ENDOCRINE GLANDS; FEMALE; FETUS; HUMANS; PREGNANCY; PREGNANCY MAINTENANCE; TROPHOBLASTS;

EID: 0033869345     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(00)00060-7     Document Type: Review

References (91)

1. Akbar A.N., Salmon M., Janossy G. The synergy between native and memory T cells during activation. Immunol. Today. 12:1991;184-188.
2. Arceci R., Shanahan J.F., Stanley E.R., Pollard J.W. Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1 regulated placental development. Proc. Natl. Acad. Sci. U.S.A. 86:1989;8818-8822.
3. Arck P., Dietl J., Clark D. From the decidual cell internet: trophoblast-recognizing T cells. Biol. Reprod. 60:1999;227-233.
4. Braakmann E., Sturm E., Vijverberg K., Krimpen B.A., Gratama J.W., Bolhuis R.L.H. Expression of CD45 isoforms by fresh and activated human γδT lymphocytes and natural killer cells. Int. Immunol. 3:1991;691-697.
5. Bulmer J.N., Pace C., Ritson A. Immunoregulatory cells in human decidua: morphology, immunohistochemistry and function. Reprod. Nutr. Dev. 28:1988;1599-1614.
6. Chen C.K., Huang S.C., Chen C.L., Yen M.R., Hsu H.C., Ho H.N. Increased expressions of CD69 but not CD25 or CD71 on endometrial T lymphocytes of nonpregnant women. Hum. Immunol. 42:1995;227-232.
7. Clark D.A., Chaouat G., Arck P.C., Mittruecker H.W., Levy G. Cytokine-dependent abortion in CBA×DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase. J. Immunol. 160:1998;545-549.
8. De Moraes Pinto M.I., Vince G.S., Flanagan B.F., Hart C.A., Johnson P.M. Localization of IL-4 and IL-4 receptors in the human term placenta, decidua and amniochorionic membranes. Immunology. 90:1996;87-94.
9. Dietl J., Horny H.P., Ruck P., Marzusch K., Kaiserling E., Griesser H., Kabelitz D. Intradecidual T lymphocytes lack immunohistochemically detectable T-cell receptors. Am. J. Reprod. Immunol. 24:1990;33-36.
10. Divers M., Bulmer J., Miller D., Lilford R. γδ T cells in human decidua. Am. J. Obstet. Gynecol. 171:1994;578-579.
11. Ekerfelt C., Matthiesen L., Berg G., Ernerudh J. Paternal leukocytes selectively increase secretion of IL-4 in peripheral blood during normal pregnancies: demonstrated by a novel one-way MLC measuring secretion. Am. J. Reprod. Immunol. 38:1997;320-326.
12. Ferrick D.A., Schrengel M.D., Mulvania T., Hsieh B., Ferlin W.G., Lepper H. Differential production of interferon-γ and interleukin-4 in response to Th1-and Th2-stimulating pathogens by γδ T cells in vivo. Nature. 373:1995;255-257.
13. 2, in rabbit blastocoelic fluid can modulate GM-CSF production by human lymphocytes. Am. J. Reprod. Immunol. 38:1997;129-139.
14. Garcia-Lloret M.I., Morrish D.W., Wegmann T.G., Honore L., Turner A.R., Guilbert L.J. Demonstration of functional cytokine-placental interactions: CSF-1 and GM-CSF stimulate human cytotrophoblast differentiation and peptide hormone secretion. Exp. Cell Res. 214:1994;46-54.
15. - decidual granular leucocyte clones. Immunology. 87:1996;609-615.
16. Guilbert L.J. There is a bias against type1 (inflammatory) cytokine expression and function in pregnancy. J. Reprod. Immunol. 32:1996;105-110.
17. Hayakawa S., Saito S., Nemoto N., Chishima F., Akiyama K., Shiraishi H., Hayakawa J., Suzuki M.K., Fujii K.T., Ichijo M., Sakurai I., Satoh K. Expression of recombinase-activating genes (RAG-1 and 2) in human decidual mononuclear cells. J. Immunol. 153:1994;4934-4939.
18. Hayakawa S., Shiraishi H., Saito S., Satoh K. Decidua as a site of extrathymic V gamma I T-cell differentiation. Am. J. Reprod. Immunol. 35:1996;233-238.
19. Haynes M.K., Smith J.B. Can Th1-like immune responses explain the immunopathology of recurrent spontaneous miscarriage? J. Reprod. Immunol. 35:1997;65-71.
20. Heyborne K., Fu Y.X., Nelson A., Farr A., O'Brien R., Born W.K. Recognition of trophoblasts by gamma delta T cells. J. Immunol. 153:1994;2918-2926.
21. Hill J.A., Polgar K., Anderson D.J. T-Helper 1 type immunity to trophoblast in women with recurrent spontaneous abortion. J. Am. Med. Assoc. 273:1995;1933-1936.
22. Hunt J.S., Robertson S.A. Uterine macrophages and environmental programming for pregnancy success. J. Reprod. Immunol. 32:1996;1-25.
23. Hunt J.S., Roby K.F. Implantation factors. Clin. Obstet. Gynecol. 37:1994;635-645.
24. Iiai T., Watanabe H., Seki S., Sugiura K., Hirokawa K., Utsuyama M., Takehashi-Iwanaga H., Iwanaga T., Abo T. Ontogeny and development of extrathymic T cells in mouse liver. Immunology. 77:1992;556-563.
25. + natural killer cells after bone marrow transplantation. Blood. 79:1992;3239-3244.
26. Jokhi P.P., King A., Sharkey A.M., Smith S.K., Loke Y.W. Screening for cytokine messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction. J. Immunol. 153:1994;4427-4435.
27. Kelemen K., Paldi A., Tinneberg H., Torok A., Szekers-Bartho J. Early recognition of pregnancy by the maternal immune system. Am. J. Reprod. Immunol. 39:1998;351-355.
28. Kelly R.W., Critchley H.O.D. A T-helper-2 bias in decidua: the prostaglandin contribution of the macrophage and trophoblast. J. Reprod. Immunol. 33:1997;181-187.
29. Kimura M., Hanawa H., Watanabe H., Ogawa M., Abo T. Synchronous expansion of intermediate TCR cells in the liver and uterus during pregnancy. Cell. Immunol. 162:1995;16-25.
30. King K.A., Loke Y.W. Human trophoblast and JEG choriocarcinoma cells are sensitive to lysis by IL-2 stimulated decidual NK cells. Cell. Immunol. 129:1990;435-441.
31. King A., Loke Y.W. Onset, nature and function of human uterine granular lymphocytes. Immunol. Today. 12:1991;432-435.
32. + population. Dev. Immunol. 1:1991;169-190.
33. + NK cells implies they are activated and capable of effector functions. Hum. Reprod. 8:1993;2061-2067.
34. + NK cells. Cell. Immunol. 183:1998;99-105.
35. Kishimoto T., Tago T., Akira S. Cytokine signal transduction. Cell. 76:1994;253-262.
36. Kodama T., Hara T., Okamoto E., Kusunoki Y., Ohara K. Characteristic changes of large granular lymphocytes that strongly express CD56 in endometrium during the menstrual cycle and early pregnancy. Hum. Reprod. 13:1998;1036-1043.
37. Krishnan L., Guilbert L.J., Russell A.S., Wegmann T.G., Mosmann T.R., Belosevic M. Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen specific IFNγ responses and increased production of T helper 2 cytokines. J. Immunol. 156:1996;644-652.
38. Lim K.J.H., Odukoya O.A., Ajjan R.A., Li T.C., Weetman A.P., Cooke I.D. Profile of cytokine mRNA expression in peri-implantation human endometrium. Mol. Hum. Reprod. 4:1998;77-81.
39. Lin P.Y., Joag S.V., Young J.D.E., Chang Y.S., Soong Y.K., Kuo T.T. Expression of perforin by natural killer cells within first trimester endometrium in humans. Biol. Reprod. 45:1991;698-703.
40. Maruyama T., Makino T., Sugi T., Matsubayashi H., Ozawa N., Nogawa S. Flow-cytometric analysis of immune cell populations in human decidua from various types of first trimester pregnancy. Hum. Immunol. 34:1992;212-218.
41. Marzi M., Vigano A., Trabattoni D., Vira M.L., Salvaggio A., Clerici E., Clerici M. Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy. Clin. Exp. Immunol. 106:1996;127-133.
42. Matos M.E., Schnier G.S., Beecher M.S., Ashman L.K., Williams D.E., Caligiari M.A. Expression of a functional c-kit receptor on a subset of natural killer cells. J. Exp. Med. 178:1993;1079-1084.
43. Miki A., Ishikawa Y., Yabe T., Furukawa H., Fujii T., Tokunaga K., Akaza T., Tadokoro K., Taketaki Y., Fuji T. Human lymphocytes obtained from decidual tissue express killer activatory receptors as well as killer inhibitory receptors. Analysis using a single strand conformation polymorphism method. Am. J. Reprod. Immunol. 39:1998;271-278.
44. Mincheva-Nilsson L., Baranov V., Yeung M.M.W., Hammarstrom S., Hammarstrom M.L. Immunomorphologic studies of human decidua-associated lymphoid cells in normal early pregnancy. J. Immunol. 152:1994;2020-2032.
45. Miranda S., Borel I.M., Margni R. Altered modulation of the in vivo antibody synthesis by placental factors from the CBA/J×DBA/2 abortion-prone mating combination. Am. J. Reprod. Immunol. 39:1998;341-349.
46. Miyajima A., Kitamura T., Harada N., Yokota T., Arai K. Cytokine receptors and signal transduction. Annu. Rev. Immunol. 10:1992;295-331.
47. Morii T., Nishikawa K., Saito S., Enomolo M., Ito A., Kwai N., Shimoya T., Ichijo M., Narita N T cell receptors are expressed but down-regulated on intradecidual T lymphocytes. Am. J. Reprod. Immunol. 29:1993;1-4.
48. Mosmann T.R., Sad S. The expanding universe of T cell subsets - Th1, Th2 and more. Immunol. Today. 17:1996;138-146.
49. Munn D.H., Zhou M., Attwood J.T., Bondarev I., Conway S.J., Marshall B., Brown C., Mellor A.L. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 281:1998;1191-1193.
50. Nagler A., Lanier L.L., Cwirls S., Phillips J.H. Comparative studies of human FcRIII-positive and negative natural killer cells. J. Immunol. 143:1989;3183-3191.
51. - natural killer cells in vivo. J. Exp. Med. 171:1990;1527-1533.
52. Nishikawa K., Saito S., Morii T., Kato Y., Narita N., Ichijo M., Ohashi Y., Takeshita T., Sugamura K. Differential expression of the interleukin-2 receptor β chain (p75) on human peripheral blood natural killer subsets. Int. Immunol. 2:1990;481-486.
53. + natural killer cells with high-affinity interleukin-2 receptors in human early pregnancy decidua. Int. Immunol. 3:1991;743-750.
54. Nishino E., Matsuzaki N., Masuhiro K., Kameda T., Taniguchi T., Takagi T., Saji F., Tanizawa O. Trophoblast derived IL-6 regulates hCG release through IL-6 receptor on human trophoblasts. J. Clin. Endocrinol. Metab. 74:1990;184-190.
55. - cells: implications for the regulation of Th1- and Th2-type responses. Int. Immunol. 9:1997;1123-1129.
56. - double-negative lymphocytes in autoimmune MRL-lpr/lpr mice. J. Exp. Med. 172:1990;7-12.
57. Ohtsuka K., Sato K., Watanabe H., Kimura M., Asakura H., Abo T. Unique order of the lymphocyte subset induction in the liver and intestine of mice during Listeria monocytogenes infection. Cell. Immunol. 161:1995;112-124.
58. Pan L., Delmonte J., Jolonen C.K., Ferrara L.M. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduce severity of experimental graft-versus-host disease. Blood. 86:1995;4422-4429.
59. Petraglia F., Florio P., Nappr C., Genazzani A.R. Peptide signaling in human placenta and membrances: autocrine, paracrine, and endocrine mechanisms. Endocr. Rev. 17:1996;156-186.
60. Phillips J.H., Hori T., Nagler A., Bhat N., Spits H., Lanier L.L. Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3εδ proteins. J. Exp. Med. 175:1992;1055-1066.
61. Piccinni M.P., Guidizi M.G., Biagiotti R., Beloni L., Giannarini L., Sampognaro S., Parronchi P., Manetti R., Annunziato F., Livi C., Romagnani S., Maggi E. Progesterone favors the development of human T helper cells producing Th-2 type cytokines and promotes both IL-4 production and membrance CD30 expression in established Th1 cell clones. J. Immunol. 155:1995;128-133.
62. Piccinni M.P., Beloni L., Livi C., Maggi E., Scarselli G., Romagnani S. Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions. Nature Med. 4:1998;1020-1024.
63. Pollard J.W., Bartocci A., Arceci R., Orlofsky A., Ladner M.B., Stanley E.R. Apparent role of the macrophage growth factor CSF-1 in placental development. Nature. 330:1987;484-486.
64. Pollard J.W., Hunt J.S., Wiktor-Jedrzejczak W., Stanley E.R. A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility. Dev. Biol. 148:1991;273-283.
65. Prussin C., Metcalfe D. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J. Immunol. Method. 188:1995;117-128.
66. Roth I., Corry D.B., Locksley R.M., Abrams J.S., Littpn M.J., Fisher S.J. Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. J. Exp. Med. 184:1996;539-548.
67. Saito S., Saito M., Motoyoshi K., Ichijo M. Enhancing effects of human macrophage colony-stimulating factor (hM-CSF) on the secretion of human chorionic gonadotropin (hCG) by human chorionic villous cells and tPA30-1 cells. Biochem. Biophys. Res. Commun. 178:1991;1099-1104.
68. Saito S., Nishikawa K., Morii T., Narita N., Enomoto N., Ichijo M. Expression of activation antigens CD69, HLA-DR, interleukin 2 receptor alpha (IL-2Rα) and IL-2Rβ on T cells of human decidua at an early stage of pregnancy. Immunology. 75:1992;710-712.
69. bright natural killer cells in the human early pregnancy decidua. Int. Immunol. 5:1993;559-563.
70. Saito S., Kasahara T., Kato Y., Ishihara Y., Ichijo M. Elevation of amniotic fluid interleukin 6 (IL-6), IL-8, and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition. Cytokine. 5:1993;81-88.
71. bright on natural killer cells. Cell. Immunol. 152:1993;605-613.
72. Saito S., Motoyoshi K., Saito M., Kato Y., Enomoto M., Nishikawa K., Morii T., Ichijo M. Localization and production of human macrophage colony-stimulating factor (hM-CSF) in human placental and decidual tissues. Lymphokine Cytokine Res. 12:1993;101-107.
73. Saito S., Saito M., Enomoto M., Ito A., Motoyoshi K., Nakagawa T., Ichijo M. Human macrophage colony-stimulating factor induces the differentiation of trophoblast. Growth Factors. 9:1993;11-19.
74. Saito S., Nishikawa K., Morii T., Narita N., Enomoto M., Ito A., Ichijo M. A study of CD45RO, CD45RA and CD29 antigen expression on human decidual T cells in an early stage of pregnancy. Immunol. Lett. 40:1994;193-197.
75. Saito S., Fukunaga R., Ichijo M., Nagata S. Expression of granulocyte colony-stimulating factor and its receptor at the fetomaternal interface in murine and human pregnancy. Growth Factors. 10:1994;135-143.
76. Saito S., Ibaraki I., Enomoto E., Ichijo M., Motoyoshi K. Macrophage colony-stimulating factor induces the growth and differentiation of normal pregnancy human cytotrophoblast cells and hydatidiform moles but does not induce the growth and differentiation of choriocarcinoma cells. Jpn. J. Cancer Res. 85:1994;245-252.
77. bright NK cells by inhibiting expression of the IL-2Rα, β, and γ Cell. Immunol. 170:1996;71-77.
78. Saito S., Harada N., Ishii N., Morii T., Sakakura S., Enomoto M., Umekage H., Nishikawa K., Narita N., Nakamura M., Sugamura K., Morikawa H. Functional expression on human trophoblasts of interleukin 4 and interleukin 7 receptor complexes with common γ chain. Biochem. Biophys. Res. Commum. 231:1997;429-434.
79. Saito S., Tsukaguchi N., Hasegawa T., Michimata T., Tsuda H., Narita N. Distribution of Th1, Th2 and Th0 and the Th1/Th2 cell ratios in human peripheral and endometrial T cells. Am. J. Reprod. Immunol. 42:1999;240-245.
80. Savino W., Dardenne M. Immune-neuroendocrine interactions. Immunol. Today. 16:1995;318-322.
81. Sawai K., Matsuzaki N., Kameda T., Hashimoto K., Okada T., Shimoya K., Nobunaga T., Taga T., Kishimoto T., Saji F. Leukemia inhibitory factor produced at the fetomaternal interface stimulates chorionic gonadotropin production: its possible implication during pregnancy, including implantation period. J. Clin. Endocrinol. Metab. 80:1995;1449-1456.
82. Simon C., Frances A., Pellicer A., Polan M.L. Cytokines in implantation. Semin. Reprod. Endocrinol. 13:1995;142-151.
83. Starkey P.M., Sargent I.L., Redman C.W.G. Cell populations in human early pregnancy decidua: characterization and isolation of large granular lymphocytes by flow cytometry. Immunology. 65:1988;129-134.
84. Testi R., Phillips J.H., Lanier L.L. T cell activation via Leu 23 (CD69). J. Immunol. 143:1989;1123-1128.
85. bright natural killer cells mediated by increased expression of the IL-2 receptor α chain. J. Reprod. Immunol. 40:1998;1-24.
86. Vassiliadou N., Bulmer J.N. Characterization of endometrial T lymphocyte subpopulations in spontaneous early pregnancy loss. Hum. Reprod. 13:1998;44-47.
87. Vassiliadou N., Bulmer J.N. Expression of CD69 activation marker by endometrial granulated lymphocytes throughout the menstrual cycle and in early pregnancy. Immunology. 94:1998;368-375.
88. Vince G.S., Johnson P.M. Is there a Th2 bias in human pregnancy? J. Reprod. Immunol. 32:1996;101-104.
89. Watanabe H., Iiai T., Kimura M., Ohtsuka K., Tanaka T., Miyasaka M., Tsuchida M., Hanawa H., Abo T. Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression. Cell. Immunol. 149:1993;331-342.
90. + T cells are present within a population of intermediate TCR cells. J. Immunol. 155:1995;2972-2983.
91. Wegmann T.G., Lin H., Guilbert L., Mosmann T.R. Bidiredectional cytokine interactions in the maternal-fetal relationship: is succcessful pregnancy a Th2 phenomenon? Immunol. Today. 14:1993;353-356.