Management of recurrent early pregnancy loss

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 51, Issue 4 SUPPL., 2006, Pages 303-310

  Stephenson, Mary D ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Infertility, female; Miscarriage; Recurrent pregnancy loss

Indexed keywords

IMMUNOGLOBULIN;

ANAMNESIS; ANATOMY; CLINICAL TRIAL; CONFERENCE PAPER; CYTOGENETICS; ENDOCRINOLOGY; EVALUATION; FEMALE; FEMALE INFERTILITY; GENETICS; GESTATIONAL AGE; HUMAN; IATROGENIC DISEASE; IMMUNOLOGY; INFECTION; LIFESTYLE; PASSIVE IMMUNIZATION; PATHOLOGY; PRIORITY JOURNAL; RECURRENT PREGNANCY LOSS; RISK FACTOR; SPONTANEOUS ABORTION; THROMBOPHILIA; ULTRASOUND;

ABORTION, HABITUAL; CHROMOSOME ABERRATIONS; FEMALE; HUMANS; PREGNANCY; RISK FACTORS; SUPPRESSOR FACTORS, IMMUNOLOGIC;

EID: 33646442797     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (47)

1. Roman E: Fetal loss rates and their relation to pregnancy order. J Epidemiol Community Health 1984;38:29-35
2. Stephenson MD: Frequency of factors associated with habitual abortion in 197 couples. Fertil Steril 1996;66:24-29
3. Stray-Pedersen B, Stray-Pedersen S: Etiologic factors and subsequent reproductive performance in 195 couples with a prior history of habitual abortion. Am J Obstet Gynecol 1984;148:140-146
4. Kline J, Stein ZA, Susser M, et al: Smoking: A risk factor for spontaneous abortion. N Engl J Med 1977;297:793-796
5. Rasch V: Cigarette, alcohol, and caffeine consumption: Risk factors for spontaneous abortion. Acta Obstet Gynecol Scand 2003;82:182-188
6. Edmonds DK, Lindsay KS, Miller JF, et al: Early embryonic mortality in women. Fertil Steril 1982;38:447-453
7. Wilcox AJ, Weinberg CR, O'Connor JF, et al: Incidence of early loss of pregnancy. N Engl J Med 1988;319:189-194
8. Hassold T, Chiu D: Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy. Hum Genet 1985;70:11-17
9. Warburton D, Fraser FC: Spontaneous abortion risks in man: Data from reproductive histories collected in a medical genetics unit. Am J Hum Genet 1964;16:1-25
10. Regan L, Braude PR, Trembath PL: Influence of past reproductive performance on risk of spontaneous abortion. Br Med J 1989;299:541-545
11. Ohno M, Maeda T, Matsunobu A: A cytogenetic study of spontaneous abortions with direct analysis of chorionic villi. Obstet Gynecol 1991;77:394-398
12. Jacobs PA, Hassold T: Human Genetics. Berlin, Springer-Verlag, 1987, pp 233-244
13. Simpson JL: Incidence and timing of pregnancy losses: Relevance to evaluating safety of early prenatal diagnosis. Am J Med Genet 1990;35:165-173
14. Plachot M: Chromosome analysis of spontaneous abortions after IVF: A European survey. Hum Reprod 1989;4:425-429
15. Warburton D, Kline J, Stein Z, et al: Does the karyotype of a spontaneous abortion predict the karyotype of a subsequent abortion? Evidence from 273 women with two karyotyped spontaneous abortions. Am J Hum Genet 1987;41:465-483
16. Coulam CB, Stephenson M, Stern JJ, et al: Immunotherapy for recurrent pregnancy loss: Analysis of results from clinical trials. Am J Reprod Immunol 1996;35:352-359
17. Lanasa MC, Hogge WA, Kubik C, et al: Highly skewed X-chromosome inactivation is associated with idiopathic recurrent spontaneous abortion. Am J Hum Genet 1999;65:252-254
18. Sangha KK, Stephenson MD, Brown CJ, et al: Extremely skewed X-chromosome inactivation is increased in women with recurrent spontaneous abortion. Am J Hum Genet 1999;65:913-917
19. Lyon MF: Gene action in the X-chromosome of the mouse (Mus musculus L.). Naturwissenschaften 1961;190:372-373
20. Beever CL, Stephenson MD, Penaherrera MS, et al: Skewed x-chromosome inactivation is associated with trisomy in women ascertained on the basis of recurrent spontaneous abortion or chromosomally abnormal pregnancies. Am J Hum Genet 2003;72:399-407
21. Stephenson MD, Awartani KA, Robinson WP: Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: A case-control study. Hum Reprod 2002;17:446-451
22. Carson SA, Branch DW: Management of recurrent early pregnancy loss. ACOG Practice Bull 2001;24:1-12
23. Rushworth FH, Backos M, Rai R, et al: Prospective pregnancy outcome in untreated recurrent miscarriers with thyroid autoantibodies. Hum Reprod 2000;15:1637-1639
24. Craig LB, Ke RW, Kutteh WH: Increased prevalence of insulin resistance in women with a history of recurrent pregnancy loss. Fertil Steril 2002;78:487-490
25. Sills ES, Perloe M, Palermo GD: Correction of hyperinsulinemia in oligo-ovulatory women with clomiphene-resistant polycystic ovary syndrome: A review of therapeutic rationale and reproductive outcomes. Eur J Obstet Gynecol Reprod Biol 2000;91:135-141
26. Daya S: Efficacy of progesterone support for pregnancy in women with recurrent miscarriage: A meta-analysis of controlled trials. Br J Obstet Gynaecol 1989;96:275-280
27. Murray MJ, Meyer WR, Zaino RJ, et al: A critical analysis of the accuracy, reproducibility, and clinical utility of histologic endometrial dating in fertile women. Fertil Steril 2004;81:1333-1343
28. Castelbaum AJ, Lessey BA: Infertility and implantation defects. Infertil Reprod Med Clin North Am 2001;12:427-446
29. Dubowy RL, Feinberg RF, Keefe DL, et al: Improved endometrial assessment using cyclin E and p27. Fertil Steril 2003;80:146-156
30. Lin PC: Reproductive outcomes in women with uterine anomalies. J Womens Health 2004;13:33-39
31. Wilson WA, Gharavi AE, Koike T, et al: International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop. Arthritis Rheum 1999;42:1309-1311
32. Kutteh WH: Antiphospholipid antibody-associated recurrent pregnancy loss: Treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol 1996;174:1584-1589
33. Rai R, Cohen H, Dave M, et al: Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). Br Med J 1997;314:253-257
34. Stephenson MD, Ballem PJ, Tsang P, et al: Treatment of antiphospholipid syndrome (APS) in pregnancy: A randomized pilot trial comparing low molecular weight heparin to unfractionated heparin. J Obstet Gynaecol Can 2004;26:729-734
35. Rai R, Backos M, Elgaddal S, et al: Factor V Leiden and recurrent miscarriage-prospective outcome of untreated pregnancies. Hum Reprod 2002;17:442-445
36. Quere I, Mercier E, Bellet H, et al: Vitamin supplementation and pregnancy outcome in women with recurrent early pregnancy loss and hyperhomocysteinemia. Fertil Steril 2001;75:823-825
37. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993;14:353-356
38. Clark DA, Vince G, Flanders KC, et al: CD56+ lymphoid cells in human first trimester pregnancy decidua as a source of novel transforming growth factor-beta 2-related immunosuppressive factors. Hum Reprod 1994;9:2270-2277
39. Szekeres-Bartho J, Autran B, Debre P, et al: Immunoregulatory effects of a suppressor factor from healthy pregnant women's lymphocytes after progesterone induction. Cell Immunol 1989;122:281-294
40. Ober C, Karrison T, Odem RR, et al: Mononuclear-cell immunisation in prevention of recurrent miscarriages: A randomised trial. Lancet 1999;354:365-369
41. The German RSA/IVIG Group: Intravenous immunoglobulin in the prevention of recurrent miscarriage. Br J Obstet Gynaecol 1994;101:1072-1077
42. Coulam CB, Krysa L, Stern JJ, et al: Intravenous immunoglobulin for treatment of recurrent pregnancy loss. Am J Reprod Immunol 1995;34:333-337
43. Christiansen OB, Mathiesen O, Husth M, et al: Placebo-controlled trial of treatment of unexplained secondary recurrent spontaneous abortions and recurrent late spontaneous abortions with i.v. immunoglobulin. Hum Reprod 1995;10:2690-2695
44. Stephenson MD, Dreher K, Houlihan E, et al: Prevention of unexplained recurrent spontaneous abortion using intravenous immunoglobulin: A prospective, randomized, double-blinded, placebo-controlled trial. Am J Reprod Immunol 1998;39:82-88
45. Perino A, Vassiliadis A, Vucetich A, et al: Short-term therapy for recurrent abortion using intravenous immunoglobulins: Results of a double-blind placebo-controlled Italian study. Hum Reprod 1997;12:2388-2392
46. Jablonowska B, Selbing A, Palfi M, et al: Prevention of recurrent spontaneous abortion by intravenous immunoglobulin: A double-blind placebo-controlled study. Hum Reprod 1999;14:838-841
47. Brigham SA, Conlon C, Farquharson RG: A longitudinal study of pregnancy outcome following idiopathic recurrent miscarriage. Hum Reprod 1999;14:2868-2871