Thermal in vivo skin electroporation pore development and charged macromolecule transdermal delivery: A numerical study of the influence of chemically enhanced lower lipid phase transition temperatures

International Journal of Heat and Mass Transfer

Volumn 51, Issue 7-8, 2008, Pages 2060-2074

  Becker, S M ^a   Kuznetsov, A V ^a  

^a North Carolina State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FINITE VOLUME METHOD; FLUIDIZATION; LIPIDS;

ELECTROPORATION; LIPID PHASE TRANSITION; STRATUM CORNEUM;

PHASE TRANSITIONS;

FINITE VOLUME METHOD; FLUIDIZATION; LIPIDS; PHASE TRANSITIONS;

EID: 39749093041     PISSN: 00179310     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijheatmasstransfer.2007.06.010     Document Type: Article

References (56)

1. Madison K.C. Barrier function of the skin: "la raison d'Être" of the epidermis. J. Invest. Dermatol. 121 2 (2003) 231-241
2. Bouwstra J.A., Honeywell-Nguyen P.L., Gooris G.S., and Ponec M. Structure of the skin barrier and its modulation by vesticular formulations. Progr. Lipid Res. 42 (2003) 1-36
3. Lombry C., Dujardin N., and Préat V. Transdermal delivery of macromolecules using skin electroporation. Pharm. Res. 17 1 (2000) 32-37
4. Denet A.R., Vanbever R., and Préat V. Skin electroporation for transdermal and topical delivery. Adv. Drug Deliver. Rev. 56 5 (2004) 659-674
5. Regnier V., De Morre N., Jadoul A., and Préat V. Mechanisms of a phosphorothioate oligonucleotide delivery by skin electroporation. Int. J. Pharm. 184 2 (1999) 147-156
6. Pliquett U.F., and A Gusbeth C. Perturbation of human skin due to application of high voltage. Bioelectrochemistry 51 1 (2000) 41-51
7. Prausnitz M.R. The effects of electric current applied to the skin: a review for transdermal drug delivery. Adv. Drug Deliv. Rev. 18 3 (1996) 395-425
8. Pliquett U., Zewert T.E., Chen T., Langer R., and Weaver J.C. Imaging of fluorescent molecule and small ion transport through human stratum corneum during high voltage pulsing: localized transport regions are involved. Biophys. Chem. 58 1-2 (1996) 185-204
9. Prausnitz M.R. Do high voltage pulses cause changes in skin structure?. J. Control. Release 40 3 (1996) 321-326
10. Pliquett U., Langer R., and Weaver J.C. Changes in the passive electrical properties of human stratum corneum due to electroporation. Biochim. Biophys. Acta 1239 2 (1995) 111-121
11. Vanbever R., and Preat V. In vivo efficacy and safety of skin electroporation. Adv. Drug Deliv. Rev. 35 (1999) 77-88
12. Vanbever R., Langers G., Montmayeur S., and Preat V. Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation. J. Control. Release 50 1-3 (1998) 225-235
13. Golden G.M., Guzek D.B., Harris R.R., Mckie J.E., and Potts R.O. Lipid thermotropic transitions in human stratum corneum. J. Invest. Dermatol. 86 3 (1986) 255-259
14. Golden G.M., Guzek D.B., Kennedy A.H., Mckie J.E., and Potts R.O. Stratum corneum lipid phase transition and water barrier properties. Biochemistry 26 8 (1987) 2382-2388
15. Tanojo H., Bouwstra J.A., Junginger H.E., and Bodde H.E. Thermal analysis studies on human skin and skin barrier modulation by fatty acids and propylene glycol. J. Therm. Anal. Calorim 57 (1999) 313-322
16. Cornwell P.A., Barry B.W., Bouwstra J.A., and Gooris G.S. Modes of action of terpene penetration enhancers in human skin; differential scanning calorimetry, small angle diffraction and enhancer uptake studies. Int. J. Pharm. 127 (1996) 9-26
17. Al-Saidan S.M., Barry B.W., and Williams A.C. Differential scanning calorimetry of human and animal stratum corneum membranes. Int. J. Pharm. 168 (1998) 17-22
18. Potts R.O., and Francoeur M.L. Lipid biophysics of water loss through the skin. Proc. Natl. Acad. Sci. USA 87 10 (1990) 3871-3873
19. Pliquett U.F., Vanbever R., Preat V., and Weaver J.C. Local transport regions (LTRs) in human stratum corneum due to long and short 'high voltage' pulses. Bioelectroch. Bioener. 47 (1998) 151-161
20. Vanbever R., Pliquett U.F., Preat V., and Weaver J.C. Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties. J. Control. Release 60 (1999) 35-47
21. Pliquett U., Gallo S., Hui S.W., Gusbeth C., and Neumann E. Local and transient changes in stratum corneum at high electric fields: contribution of Joule heating. Bioelectrochemistry 67 1 (2005) 37-46
22. Gallo S.A., Sen A., Hensen M.L., and Hui S.W. Temperature-dependent electrical and ultrastructural characterization of porcine skin upon electroporation. Biophys. J. 82 (2002) 109-119
23. Williams A.C., and Barry B.W. Penetration enhancers. Adv. Drug Deliv. Rev. 56 5 (2004) 603-618
24. Pillai O., and Panchagnula R. Transdermal iontophoresis of insulin - V. Effect of terpenes. J. Control. Release 88 2 (2003) 287-296
25. Harden J.L., and Viovy J.-L. Numerical studies of pulsed iontophoresis through model membranes. J. Control. Release 38 2-3 (1996) 129-139
26. Mollee T.R., Anissimov Y.G., and Roberts M.R. Periodic electric field enhanced transport through membranes. J. Membr. Sci. 278 1-2 (2006) 290-300
27. Zhu H.G., Peck K.D., Li S.K., Ghanem A.H., and Higuchi W.I. Quantifications of pore induction in human epidermal membrane during iontophoresis: the importance of background electrolyte solution. J. Pharm. Sci. 90 7 (2001) 932-942
28. Li S.K., Ghanem A.H., Teng C.L., Hardee G.E., and Higuchi W.I. Iontophoretic transport of oligonucleotides across human epidermal membrane: a study of the Nernst-Planck model. J. Pharm. Sci. 90 7 (2001) 915-931
29. Martin G.T., Pliquett U.F., and Weaver J.C. Theoretical analysis of localized heating in human skin subjected to high voltage pulses. Bioelectrochemistry 57 (2002) 55-64
30. Millington P.F., and Wilkinson R. Skin (1983), Cambridge University Press, Cambridge, Great Britain
31. Hendriks F.M., Brokken D., Oomens C.W.J., and Baaijens F.P.T. Influence of hydration and experimental length scale on the mechanical response of human skin in vivo, using optical coherence tomography. Skin Research and Technology 10 (2004) 231-241
32. Pennes H.H. Analysis of tissue and arterial blood temperatures in the resting forearm. J. Appl. Physiol. 1 (1948) 93-122
33. Duck F.A. Physical Properties of Tissue: A Comprehensive Reference Book (1990), Academic Press, London
34. Svaasand L.O., Randeberg L.L., Aguilar G., Majaron B., Kimel S., Lavernia E.J., and Nelson J.S. Cooling Efficiency of cryogen spray during laser therapy of skin. Lasers Surg. Med. 32 2 (2003) 137-142
35. Chato J.C., and Lee R.C. The future of biothermal engineering. Ann. NY Acad. Sci. 858 (1998) 1-20
36. Wilson S.B., and Spence V.A. A tissue heat transfer model for relating dynamic skin temperature changes to physiological parameters. Phys. Med. Biol. 33 8 (1988) 895-912
37. Wainwright P. Thermal effects of radiation from cellular telephones. Phys. Med. Biol. 45 8 (2000) 2363-2372
38. Chizmadzhev Y.A., Indenbom A.V., Kuzmin P.I., Galichenko S.V., Weaver J.C., and Potts R.O. Electrical properties of skin at moderate voltages: contribution of appendageal macropores. Biophys. J. 74 2 (1998) 843-856
39. Zaharoff D.A., Barr R.C., Li C.-Y., and Yuan F. Electromobility of plasmid DNA in tumor tissues during electric field-mediated gene delivery. Gene Therapy 9 19 (2002) 1286-1290
40. Bureau M.F., Gehl J., Deleuze V., Mir L.M., and Scherman D. Importance of association between permeabilization and electrophoretic forces for intramuscular DNA electrotransfer. Biochim. Biophys. Acta: General Subjects 1474 3 (2000) 353-359
41. Satkauskas S., Andre F., Bureau M.F., Scherman D., Miklavcic D., and Mir L.M. Electrophoretic component of electrical pulses determines the efficacy of in vivo DNA electrotransfer. Human Gene Therapy 16 10 (2005) 1194-1201
42. Planck M. Über die erregung von elektrizität und wärme in elektrolyten. Ann. Phys. Chem. 39 (1890) 161-186
43. Netti P.A., Berk D.A., Swartz M.A., Grodzinsky A.J., and Jain R.K. Role of extracellular matrix assembly in interstital transport in solid tumors. Cancer Res. 60 (2000) 2497-2503
44. Zaharoff D.A., and Yuan F. Effects of pulse strength and pulse duration on in vitro DNA electromobility. Bioelectrochemistry 62 1 (2004) 37-45
45. Stellwagen N.C. DNA mobility anomalies are determined primarily by polyacrylamide gel concentration, not gel pore size. Electrophoresis 18 (1997) 34-44
46. Silva C.L., Nunes S.C.C., Eusebio M.E.S., Sousa J.J.S., and Pais A.A.C.C. Study of human stratum corneum and extracted lipids by thermomicroscopy and DSC. Chem. Phys. Lipids 140 1-2 (2006) 36-47
47. Silva C.L., Nunes S.C.C., Eusebio M.E.S., Pais A.A.C.C., and Sousa J.J.S. Thermal behaviour of human stratum corneum - a differential scanning calorimetry study at high scanning rates. Skin Pharmacol. Physiol. 19 3 (2006) 132-139
48. White S.H., Mirejovsky D., and King G.I. Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum - an X-ray-diffraction study. Biochemistry 27 10 (1988) 3725-3732
49. Voller V.R., and Brent A.D. The modeling of heat, mass and solute transport in solidification systems. Int. J. Heat Mass Transfer 32 9 (1989) 1719-1732
50. Ozisik M.N. Heat Conduction (1993), John Wiley & Sons, New York, NY, USA
51. Bart G.C.J., and Van der Laag P.C. Modeling of arbitrary-shaped specific and latent heat curves in phase-change storage simulation routines. Trans. ASME J. Solar Energy Eng. 112 (1990) 29-33
52. Roy S.K., and Avanic B.L. Turbulent heat transfer with phase change material suspensions. Int. J. Heat Mass Transfer 44 12 (2001) 2277-2285
53. Craane van Hinsberg W.H.M., Verhoef J.C., Junginger H.E., and Bodde H.E. Thermoelectrical analysis of the human skin barrier. Thermochim. Acta. 248 (1995) 303-318
54. Dujardin N., Staes E., Kalia Y., Clarys P., Guy R., and Preat V. In vivo assessment of skin electroporation using square wave pulses. J. Control. Release 79 1-3 (2002) 219-227
55. Pliquett U., and Gusbeth C. Surface area involved in transdermal transport of charged species due to skin electroporation. Bioelectrochemistry 65 1 (2004) 27-32
56. S.V. Patankar, Numerical Heat Transfer and Fluid Flow, Hemisphere, Washington DC, 1980.