메뉴 건너뛰기




Volumn 59, Issue , 2008, Pages 199-212

Genetic determinants of aggressive breast cancer

Author keywords

Biomarker; Drug target; Genetic marker; Inflammatory breast cancer

Indexed keywords

BIOLOGICAL MARKER;

EID: 39649105682     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.59.060106.184830     Document Type: Review
Times cited : (17)

References (70)
  • 2
    • 33744502855 scopus 로고    scopus 로고
    • Cancer biomarkers - an invitation to the table
    • Dalton WS, Friend SH. 2006. Cancer biomarkers - an invitation to the table. Science 312:1165-68
    • (2006) Science , vol.312 , pp. 1165-1168
    • Dalton, W.S.1    Friend, S.H.2
  • 4
    • 33845193373 scopus 로고    scopus 로고
    • Microarrays to identify new therapeutic strategies for cancer
    • Sears C, Armstrong SA. 2007. Microarrays to identify new therapeutic strategies for cancer. Adv. Cancer Res. 96:51-74
    • (2007) Adv. Cancer Res , vol.96 , pp. 51-74
    • Sears, C.1    Armstrong, S.A.2
  • 5
    • 0034601499 scopus 로고    scopus 로고
    • Molecular switches in metastasis
    • Ridley A. 2000. Molecular switches in metastasis. Nature 406(6795):466-67
    • (2000) Nature , vol.406 , Issue.6795 , pp. 466-467
    • Ridley, A.1
  • 6
    • 33744493093 scopus 로고    scopus 로고
    • The new era in cancer research
    • Varmus H. 2006. The new era in cancer research. Science 312(5777):1162-65
    • (2006) Science , vol.312 , Issue.5777 , pp. 1162-1165
    • Varmus, H.1
  • 7
    • 9244222261 scopus 로고    scopus 로고
    • Targeted cancer therapy
    • Sawyers C. 2004. Targeted cancer therapy. Nature 432(7015):294-97
    • (2004) Nature , vol.432 , Issue.7015 , pp. 294-297
    • Sawyers, C.1
  • 10
    • 0021958939 scopus 로고
    • Inflammatory breast cancer: The experience of the Surveillance, Epidemiology, and End Results (SEER) program
    • Levine PH, Steinhorn SC, Ries LG, et al. 1985. Inflammatory breast cancer: the experience of the Surveillance, Epidemiology, and End Results (SEER) program. J. Natl. Cancer Inst. 74:291-97
    • (1985) J. Natl. Cancer Inst , vol.74 , pp. 291-297
    • Levine, P.H.1    Steinhorn, S.C.2    Ries, L.G.3
  • 11
    • 0034469922 scopus 로고    scopus 로고
    • Molecular biology of breast cancer metastasis. Inflammatory breast cancer: Clinical syndrome and molecular determinants
    • Kleer CG, van Golen KL, Merajver SD. 2000. Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants. Breast Cancer Res. 2(6):423-29
    • (2000) Breast Cancer Res , vol.2 , Issue.6 , pp. 423-429
    • Kleer, C.G.1    van Golen, K.L.2    Merajver, S.D.3
  • 12
    • 18844470858 scopus 로고    scopus 로고
    • Breast conservation and prolonged chemotherapy for locally advanced breast cancer: The University of Michigan experience
    • Merajver SD, Weber BL, Cody R, et al. 1997. Breast conservation and prolonged chemotherapy for locally advanced breast cancer: the University of Michigan experience. J. Clin. Oncol. 15(8):2873-81
    • (1997) J. Clin. Oncol , vol.15 , Issue.8 , pp. 2873-2881
    • Merajver, S.D.1    Weber, B.L.2    Cody, R.3
  • 13
    • 7044272570 scopus 로고    scopus 로고
    • 12a. Low J, Berman A, Steinber S, et al. 2004. Long term follow up for locally advanced and inflammatory breast cancer patients treated with multimodality therapy. J. Clin. Oncol. 22:4065-74
    • 12a. Low J, Berman A, Steinber S, et al. 2004. Long term follow up for locally advanced and inflammatory breast cancer patients treated with multimodality therapy. J. Clin. Oncol. 22:4065-74
  • 14
    • 1842530208 scopus 로고    scopus 로고
    • Paclitaxel improves the prognosis in estrogen receptor negative inflammatory breast cancer: The M.D. Anderson Cancer Center experience
    • Cristofanilli M, Gonzalez-Anugulo AM, Buzdar AU, et al. 2004. Paclitaxel improves the prognosis in estrogen receptor negative inflammatory breast cancer: The M.D. Anderson Cancer Center experience. Clin. Breast Cancer 4:415-19
    • (2004) Clin. Breast Cancer , vol.4 , pp. 415-419
    • Cristofanilli, M.1    Gonzalez-Anugulo, A.M.2    Buzdar, A.U.3
  • 15
    • 0001512931 scopus 로고
    • Inflammatory carcinoma of the breast: A report of twenty-eight cases from the breast clinic of Memorial Hospital
    • Lee BJ, Tannenbaum ND. 1924. Inflammatory carcinoma of the breast: a report of twenty-eight cases from the breast clinic of Memorial Hospital. Surg. Gynecol. Obstet. 39:580-95
    • (1924) Surg. Gynecol. Obstet , vol.39 , pp. 580-595
    • Lee, B.J.1    Tannenbaum, N.D.2
  • 16
    • 0242693136 scopus 로고    scopus 로고
    • Inflammatory breast cancer: Clinical progress and the main problems that must be addressed
    • Giordano SH, Hortobagyi GN. 2003. Inflammatory breast cancer: clinical progress and the main problems that must be addressed. Breast Cancer Res. 5(6):284-28
    • (2003) Breast Cancer Res , vol.5 , Issue.6 , pp. 284-328
    • Giordano, S.H.1    Hortobagyi, G.N.2
  • 17
    • 0032835343 scopus 로고    scopus 로고
    • A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype
    • van Golen KL, Davies S, Wu ZF, et al. 1999. A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype. Clin. Cancer Res. 5(9):2511-19
    • (1999) Clin. Cancer Res , vol.5 , Issue.9 , pp. 2511-2519
    • van Golen, K.L.1    Davies, S.2    Wu, Z.F.3
  • 18
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • van Golen KL, Wu ZF, Qiao XT, et al. 2000. RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res. 60(20):5832-38
    • (2000) Cancer Res , vol.60 , Issue.20 , pp. 5832-5838
    • van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3
  • 19
    • 0029677185 scopus 로고    scopus 로고
    • Human breast cancer cell lines as models of growth regulation and disease progression
    • Ethier SP. 1996. Human breast cancer cell lines as models of growth regulation and disease progression. J. Mammary Gland Biol. Neoplasia 1:111-21
    • (1996) J. Mammary Gland Biol. Neoplasia , vol.1 , pp. 111-121
    • Ethier, S.P.1
  • 20
    • 0029693908 scopus 로고    scopus 로고
    • Review of known prognostic variables
    • Kaufman M. 2000. Review of known prognostic variables. Results Probl. Cell Differ. 140:77-87
    • (2000) Results Probl. Cell Differ , vol.140 , pp. 77-87
    • Kaufman, M.1
  • 21
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon DJ, Godolphin W, Jones LA, et al. 1989. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244(4905):707-12
    • (1989) Science , vol.244 , Issue.4905 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3
  • 22
    • 7044224706 scopus 로고    scopus 로고
    • Mutational spectrum of p53 mutations in primary breast and ovarian tumors
    • Feki A, Irminger-Finger I. 2004. Mutational spectrum of p53 mutations in primary breast and ovarian tumors. Crit. Rev. Oncol. Hematol. 52:103-16
    • (2004) Crit. Rev. Oncol. Hematol , vol.52 , pp. 103-116
    • Feki, A.1    Irminger-Finger, I.2
  • 23
    • 0026694826 scopus 로고
    • Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
    • Moll UM, Riou G, Levine PH. 1992. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc. Natl. Acad. Sci. USA 89:7262-66
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7262-7266
    • Moll, U.M.1    Riou, G.2    Levine, P.H.3
  • 24
    • 0027373834 scopus 로고
    • Poor prognosis of p53 gene mutation and nuclear overexpression of p53 protein in inflammatory breast carcinoma
    • Riou G, Le MG, Travagli JP, et al. 1993. Poor prognosis of p53 gene mutation and nuclear overexpression of p53 protein in inflammatory breast carcinoma. J. Natl. Cancer Inst. 85:1765-67
    • (1993) J. Natl. Cancer Inst , vol.85 , pp. 1765-1767
    • Riou, G.1    Le, M.G.2    Travagli, J.P.3
  • 25
    • 4644232467 scopus 로고    scopus 로고
    • p53 expression as a prognostic marker in inflammatory breast cancer
    • Gonzalez-Angulo AM, Sneige N, Kau SW, et al. 2004. p53 expression as a prognostic marker in inflammatory breast cancer. Clin. Cancer Res. 10:6215-21
    • (2004) Clin. Cancer Res , vol.10 , pp. 6215-6221
    • Gonzalez-Angulo, A.M.1    Sneige, N.2    Kau, S.W.3
  • 26
    • 5444230567 scopus 로고    scopus 로고
    • Transcriptional regulation of cadherins during development and carcinogenesis
    • Peinado H, Portillo F, Cano A. 2004. Transcriptional regulation of cadherins during development and carcinogenesis. Int. J. Dev. Biol. 48:365-75
    • (2004) Int. J. Dev. Biol , vol.48 , pp. 365-375
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 27
    • 0035031712 scopus 로고    scopus 로고
    • Persistent E-cadherin expression in inflammatory breast cancer
    • Kleer CG, van Golen K, Braun T, et al. 2001. Persistent E-cadherin expression in inflammatory breast cancer. Mod. Pathol. 14:458-64
    • (2001) Mod. Pathol , vol.14 , pp. 458-464
    • Kleer, C.G.1    van Golen, K.2    Braun, T.3
  • 28
    • 0027772231 scopus 로고
    • Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma
    • Gamallo C, Palacios J, Suarez A, et al. 1993. Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am. J. Pathol. 142:987-93
    • (1993) Am. J. Pathol , vol.142 , pp. 987-993
    • Gamallo, C.1    Palacios, J.2    Suarez, A.3
  • 29
    • 0027530351 scopus 로고
    • Expression of E-cadherin cell adhesion molecule in human breast cancer tissues and its relationship to metastasis
    • Oka H, Shiozaki H, Kobayashi K, et al. 1993. Expression of E-cadherin cell adhesion molecule in human breast cancer tissues and its relationship to metastasis. Cancer Res. 53:1696-701
    • (1993) Cancer Res , vol.53 , pp. 1696-1701
    • Oka, H.1    Shiozaki, H.2    Kobayashi, K.3
  • 30
    • 0035392961 scopus 로고    scopus 로고
    • An intact overexpressed E-cadherin/alpha,beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma
    • Tomlinson JS, Alpaugh ML, Barsky SH. 2001. An intact overexpressed E-cadherin/alpha,beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma. Cancer Res. 61:5231-41
    • (2001) Cancer Res , vol.61 , pp. 5231-5241
    • Tomlinson, J.S.1    Alpaugh, M.L.2    Barsky, S.H.3
  • 31
    • 12144287780 scopus 로고    scopus 로고
    • Immunophenotypic analysis of inflammatory breast cancers: Identification of an 'inflammatory signature'
    • Charafe-Jauffret E, Tarpin C, Bardou V-J, et al. 2004. Immunophenotypic analysis of inflammatory breast cancers: identification of an 'inflammatory signature'. J. Pathol. 202:265-73
    • (2004) J. Pathol , vol.202 , pp. 265-273
    • Charafe-Jauffret, E.1    Tarpin, C.2    Bardou, V.-J.3
  • 32
    • 0031905861 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flt 1) and VEGF receptor 3 (Flt 4)
    • Achen M, Jeltsch M, Kukk E, et al. 1998. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flt 1) and VEGF receptor 3 (Flt 4). Proc. Natl. Acad. Sci. USA 95:548-53
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 548-553
    • Achen, M.1    Jeltsch, M.2    Kukk, E.3
  • 33
    • 0032758072 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) family members in breast cancer
    • Kurebayashi J, Ostuski T, Kunisue H, et al. 1999. Expression of vascular endothelial growth factor (VEGF) family members in breast cancer. J. Cancer Res. 90:977-81
    • (1999) J. Cancer Res , vol.90 , pp. 977-981
    • Kurebayashi, J.1    Ostuski, T.2    Kunisue, H.3
  • 34
    • 0031465588 scopus 로고    scopus 로고
    • The GTP-binding protein Rho
    • Ridley A. 1997. The GTP-binding protein Rho. Int. J. Biochem. Cell Biol. 29:1225-29
    • (1997) Int. J. Biochem. Cell Biol , vol.29 , pp. 1225-1229
    • Ridley, A.1
  • 35
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A. 2002. Rho GTPases in cell biology. Nature 420:629-35
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 37
    • 0028008555 scopus 로고
    • Low molecular weight GTP-binding proteins: Molecular switches regulating diverse cellular functions
    • Wagner AC, Williams JA. 1994. Low molecular weight GTP-binding proteins: molecular switches regulating diverse cellular functions. Am. J. Physiol. 266:G1-14
    • (1994) Am. J. Physiol , vol.266
    • Wagner, A.C.1    Williams, J.A.2
  • 38
    • 33646149996 scopus 로고    scopus 로고
    • RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility
    • Yao H, Dashner EJ, van Golen CM, et al. 2006. RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Oncogene 25(16):2285-96
    • (2006) Oncogene , vol.25 , Issue.16 , pp. 2285-2296
    • Yao, H.1    Dashner, E.J.2    van Golen, C.M.3
  • 41
    • 6344231714 scopus 로고    scopus 로고
    • Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility
    • Wheeler AP, Ridley AJ. 2004. Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp. Cell Res. 301:43-49
    • (2004) Exp. Cell Res , vol.301 , pp. 43-49
    • Wheeler, A.P.1    Ridley, A.J.2
  • 42
    • 12144286354 scopus 로고    scopus 로고
    • Validation of a tissue microarray to study differential protein expression in inflammatory and noninflammatory breast cancer
    • Van Den Eynden GG, Van Der Auwera I, Van Laere S, et al. 2004. Validation of a tissue microarray to study differential protein expression in inflammatory and noninflammatory breast cancer. Breast Cancer Res. Treat. 85:13-22
    • (2004) Breast Cancer Res. Treat , vol.85 , pp. 13-22
    • Van Den Eynden, G.G.1    Van Der Auwera, I.2    Van Laere, S.3
  • 43
    • 0036168355 scopus 로고    scopus 로고
    • Characterization of RhoC expression in benign and malignant breast disease - a potential new marker for small breast carcinomas with metastatic ability
    • Kleer CG, van Golen KL, Zhang Y, et al. 2002. Characterization of RhoC expression in benign and malignant breast disease - a potential new marker for small breast carcinomas with metastatic ability. Am. J. Pathol. 160:579-84
    • (2002) Am. J. Pathol , vol.160 , pp. 579-584
    • Kleer, C.G.1    van Golen, K.L.2    Zhang, Y.3
  • 44
    • 25844484093 scopus 로고    scopus 로고
    • RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast
    • Kleer CG, Griffith KA, Sabel MS, et al. 2005. RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast. Breast Cancer Res. Treat. 93:101-10
    • (2005) Breast Cancer Res. Treat , vol.93 , pp. 101-110
    • Kleer, C.G.1    Griffith, K.A.2    Sabel, M.S.3
  • 45
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer
    • Kamai T, Tsujii T, Arai K, et al. 2003. Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer. Clin. Cancer Res. 9:2632-41
    • (2003) Clin. Cancer Res , vol.9 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3
  • 46
    • 0038679226 scopus 로고    scopus 로고
    • Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
    • Horiuchi A, Imai T, Wang C, et al. 2003. Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab. Invest. 83:861-70
    • (2003) Lab. Invest , vol.83 , pp. 861-870
    • Horiuchi, A.1    Imai, T.2    Wang, C.3
  • 47
    • 0031974721 scopus 로고    scopus 로고
    • Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas
    • Suwa H, Ohshio G, Imamura T, et al. 1998. Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. Br. J. Cancer 77:147-52
    • (1998) Br. J. Cancer , vol.77 , pp. 147-152
    • Suwa, H.1    Ohshio, G.2    Imamura, T.3
  • 48
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark EA, Golub TR, Lander ES, et al. 2000. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406:532-35
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3
  • 49
    • 3042739357 scopus 로고    scopus 로고
    • Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis
    • Wang W, Yang LY, Huang GW, et al. 2004. Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis. Br. J. Cancer 90:2349-55
    • (2004) Br. J. Cancer , vol.90 , pp. 2349-2355
    • Wang, W.1    Yang, L.Y.2    Huang, G.W.3
  • 50
    • 24344486013 scopus 로고    scopus 로고
    • RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
    • Hakem A, Sanchez-Sweatman O, You-Ten A, et al. 2005. RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev. 19:1974-79
    • (2005) Genes Dev , vol.19 , pp. 1974-1979
    • Hakem, A.1    Sanchez-Sweatman, O.2    You-Ten, A.3
  • 51
    • 0034518232 scopus 로고    scopus 로고
    • RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells
    • van Golen KL, Wu ZF, Qiao XT, et al. 2000. RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells. Neoplasia 2:418-25
    • (2000) Neoplasia , vol.2 , pp. 418-425
    • van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3
  • 52
    • 1642268839 scopus 로고    scopus 로고
    • RhoC induces differential expression of genes involved in invasion and metastasis in MCF10A breast cells
    • Wu M, Wu ZF, Kumar-Sinha C, et al. 2004. RhoC induces differential expression of genes involved in invasion and metastasis in MCF10A breast cells. Breast Cancer Res. Treat. 84:3-12
    • (2004) Breast Cancer Res. Treat , vol.84 , pp. 3-12
    • Wu, M.1    Wu, Z.F.2    Kumar-Sinha, C.3
  • 53
    • 17744413024 scopus 로고    scopus 로고
    • Perbal B. 2001. The CCN family of cell growth regulators: a new family of normal and pathologic cell growth and differentiation regulators: lessons from the first international workshop on CCN gene family. Bull. Cancer 88:645-49
    • Perbal B. 2001. The CCN family of cell growth regulators: a new family of normal and pathologic cell growth and differentiation regulators: lessons from the first international workshop on CCN gene family. Bull. Cancer 88:645-49
  • 54
    • 0032819849 scopus 로고    scopus 로고
    • Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia
    • Hurvitz JR, Suwairi WM, Van Hul W, et al. 1999. Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia. Nat. Genet. 23:94-98
    • (1999) Nat. Genet , vol.23 , pp. 94-98
    • Hurvitz, J.R.1    Suwairi, W.M.2    Van Hul, W.3
  • 55
    • 13044295427 scopus 로고    scopus 로고
    • WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
    • Pennica D, Swanson TA, Welsh JW, et al. 1998. WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc. Natl. Acad. Sci. USA 95:14717-22
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14717-14722
    • Pennica, D.1    Swanson, T.A.2    Welsh, J.W.3
  • 56
    • 0033514408 scopus 로고    scopus 로고
    • The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: A clue for a role of NOVH in cell-adhesion signaling
    • Perbal B, Martinerie C, Sainson R, et al. 1999. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling. Proc. Natl. Acad. Sci. USA 96:869-74
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 869-874
    • Perbal, B.1    Martinerie, C.2    Sainson, R.3
  • 57
    • 0036970842 scopus 로고    scopus 로고
    • The role of the IGF system in cancer: From basic to clinical studies and clinical applications
    • Moschos SJ, Mantzoros CS. 2002. The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology 63:317-32
    • (2002) Oncology , vol.63 , pp. 317-332
    • Moschos, S.J.1    Mantzoros, C.S.2
  • 58
    • 0033562985 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein related protein 1 (IGFBP-rP1) is a potential tumor suppressor for prostate cancer
    • Sprenger CC, Damon SE, Hwa V, et al. 1999. Insulin-like growth factor binding protein related protein 1 (IGFBP-rP1) is a potential tumor suppressor for prostate cancer. Cancer Res. 59:2370-75
    • (1999) Cancer Res , vol.59 , pp. 2370-2375
    • Sprenger, C.C.1    Damon, S.E.2    Hwa, V.3
  • 59
    • 0032516239 scopus 로고    scopus 로고
    • Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas
    • Burger A, Zhang X, Li H, et al. 1998. Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas. Oncogene 16:2459-67
    • (1998) Oncogene , vol.16 , pp. 2459-2467
    • Burger, A.1    Zhang, X.2    Li, H.3
  • 60
    • 85047695306 scopus 로고    scopus 로고
    • WISP3 is a novel tumor suppressor gene of inflammatory breast cancer
    • Kleer CG, Zhang Y, Pan Q, et al. 2002. WISP3 is a novel tumor suppressor gene of inflammatory breast cancer. Oncogene 21(20):3172-80
    • (2002) Oncogene , vol.21 , Issue.20 , pp. 3172-3180
    • Kleer, C.G.1    Zhang, Y.2    Pan, Q.3
  • 61
    • 14844339132 scopus 로고    scopus 로고
    • WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer
    • Kleer CG, Zhang Y, Pan Q, et al. 2004. WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer. Breast Cancer Res. 6(2):R110-15
    • (2004) Breast Cancer Res , vol.6 , Issue.2
    • Kleer, C.G.1    Zhang, Y.2    Pan, Q.3
  • 62
    • 39649103752 scopus 로고    scopus 로고
    • Deleted in proof
    • Deleted in proof
  • 63
    • 34447635028 scopus 로고    scopus 로고
    • 2 005. Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells
    • Zhang Y, Pan Q, Zhong H, et al. 2 005. Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells. Breast Cancer Res. 7(6):R1080-89
    • Breast Cancer Res , vol.7 , Issue.6
    • Zhang, Y.1    Pan, Q.2    Zhong, H.3
  • 64
    • 33745611183 scopus 로고    scopus 로고
    • Molecular biology of inflammatory breast cancer: Applications to diagnosis, prognosis, and therapy
    • Wu M, Merajver SD. 2006. Molecular biology of inflammatory breast cancer: applications to diagnosis, prognosis, and therapy. Breast Dis. 22:25-34
    • (2006) Breast Dis , vol.22 , pp. 25-34
    • Wu, M.1    Merajver, S.D.2
  • 65
    • 0033777262 scopus 로고    scopus 로고
    • Inhibition of Rho GTPases using protein geranylgeranyltransferase I inhibitors
    • Sebti SM, Hamilton AD. 2000. Inhibition of Rho GTPases using protein geranylgeranyltransferase I inhibitors. Methods Enzymol. 325:381-88
    • (2000) Methods Enzymol , vol.325 , pp. 381-388
    • Sebti, S.M.1    Hamilton, A.D.2
  • 66
    • 0026640530 scopus 로고
    • Post-translational modifications of p21rho proteins
    • Adamson P, Marshall CJ, Hall A, et al. 1992. Post-translational modifications of p21rho proteins. J. Biol. Chem. 267(28):20033-38
    • (1992) J. Biol. Chem , vol.267 , Issue.28 , pp. 20033-20038
    • Adamson, P.1    Marshall, C.J.2    Hall, A.3
  • 67
    • 0031970317 scopus 로고    scopus 로고
    • Membrane association and targeting of prenylated Ras-like GTPases
    • Seabra MC. 1998. Membrane association and targeting of prenylated Ras-like GTPases. Cell. Signal. 10(3):167-72
    • (1998) Cell. Signal , vol.10 , Issue.3 , pp. 167-172
    • Seabra, M.C.1
  • 68
    • 0028892646 scopus 로고
    • Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity
    • Lebowitz PF, Davide JP, Prendergast GC. 1995. Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity. Mol. Cell. Biol. 15(12):6613-22
    • (1995) Mol. Cell. Biol , vol.15 , Issue.12 , pp. 6613-6622
    • Lebowitz, P.F.1    Davide, J.P.2    Prendergast, G.C.3
  • 69
    • 0033860183 scopus 로고    scopus 로고
    • RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors
    • Liu A, Du W, Liu JP, et al. 2000. RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors. Mol. Cell. Biol. 20(16):6105-13
    • (2000) Mol. Cell. Biol , vol.20 , Issue.16 , pp. 6105-6113
    • Liu, A.1    Du, W.2    Liu, J.P.3
  • 70
    • 0036599583 scopus 로고    scopus 로고
    • Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor
    • van Golen KL, Bao L, DiVito MM, et al. 2002. Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor. Mol. Cancer Ther. 1(8):575-83
    • (2002) Mol. Cancer Ther , vol.1 , Issue.8 , pp. 575-583
    • van Golen, K.L.1    Bao, L.2    DiVito, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.