메뉴 건너뛰기




Volumn 93, Issue 2, 2005, Pages 101-110

RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast

Author keywords

Biomarkers; Breast cancer; Inflammatory breast cancer; Pathology; Rhoc; Tissue microarrays

Indexed keywords

BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; DOXORUBICIN; HORMONE RECEPTOR; PACLITAXEL; POLYCLONAL ANTIBODY; POLYCLONAL RHOC ANTIBODY; PROTEIN RHOC; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 25844484093     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-005-4170-6     Document Type: Article
Times cited : (108)

References (40)
  • 3
    • 0035495969 scopus 로고    scopus 로고
    • Prognostic factors in breast cancer: Current and new predictors of metastasis
    • DF Hayes C Isaacs V Stearns 2001 Prognostic factors in breast cancer: current and new predictors of metastasis J Mammary Gland Biol Neoplasia 6 375 392
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , pp. 375-392
    • Hayes, D.F.1    Isaacs, C.2    Stearns, V.3
  • 4
    • 0032412988 scopus 로고    scopus 로고
    • Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful?
    • DF Hayes B Trock AL Harris 1998 Assessing the clinical impact of prognostic factors: when is "statistically significant" clinically useful? Breast Cancer Res Treat 52 305 319
    • (1998) Breast Cancer Res Treat , vol.52 , pp. 305-319
    • Hayes, D.F.1    Trock, B.2    Harris, A.L.3
  • 6
    • 0034001315 scopus 로고    scopus 로고
    • Do we need prognostic factors in nodal-negative breast cancer?
    • Hayes 2000 Do we need prognostic factors in nodal-negative breast cancer? Arbiter Eur J Cancer 36 302 306
    • (2000) Arbiter Eur J Cancer , vol.36 , pp. 302-306
    • Hayes1
  • 7
    • 0032835343 scopus 로고    scopus 로고
    • A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype
    • KL van Golen S Davies ZF Wu Y Wang CD Bucana H Root S Chandrasekharappa M Strawderman SP Ethier SD Merajver 1999 A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype Clin Cancer Res 5 2511 2519
    • (1999) Clin Cancer Res , vol.5 , pp. 2511-2519
    • Van Golen, K.L.1    Davies, S.2    Wu, Z.F.3    Wang, Y.4    Bucana, C.D.5    Root, H.6    Chandrasekharappa, S.7    Strawderman, M.8    Ethier, S.P.9    Merajver, S.D.10
  • 8
    • 0034518232 scopus 로고    scopus 로고
    • RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells
    • KL van Golen ZF Wu XT Qiao L Bao SD Merajver 2000 RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells Neoplasia 2 418 425
    • (2000) Neoplasia , vol.2 , pp. 418-425
    • Van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3    Bao, L.4    Merajver, S.D.5
  • 9
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • KL van Golen ZF Wu XT Qiao LW Bao SD Merajver 2000 RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype Cancer Res 60 5832 5838
    • (2000) Cancer Res , vol.60 , pp. 5832-5838
    • Van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3    Bao, L.W.4    Merajver, S.D.5
  • 10
    • 0036168355 scopus 로고    scopus 로고
    • Characterization of RhoC expression in benign and malignant breast disease:a potential new marker for small breast carcinomas with metastatic ability
    • CG Kleer KL van Golen Y Zhang ZF Wu MA Rubin SD Merajver 2002 Characterization of RhoC expression in benign and malignant breast disease:a potential new marker for small breast carcinomas with metastatic ability Am J Pathol 160 579 584
    • (2002) Am J Pathol , vol.160 , pp. 579-584
    • Kleer, C.G.1    Van Golen, K.L.2    Zhang, Y.3    Wu, Z.F.4    Rubin, M.A.5    Merajver, S.D.6
  • 13
    • 0027404657 scopus 로고
    • Method for grading breast cancer
    • EW Elston IO Ellis 1993 Method for grading breast cancer J Clin Pathol 46 189 190
    • (1993) J Clin Pathol , vol.46 , pp. 189-190
    • Elston, E.W.1    Ellis, I.O.2
  • 14
    • 0034847476 scopus 로고    scopus 로고
    • Relational database structure to manage high-density tissue microarray data and images for pathology studies focusing on clinical outcome: The prostate specialized program of research excellence model
    • S Manley NR Mucci AM De Marzo MA Rubin 2001 Relational database structure to manage high-density tissue microarray data and images for pathology studies focusing on clinical outcome: the prostate specialized program of research excellence model Am J Pathol 159 837 843
    • (2001) Am J Pathol , vol.159 , pp. 837-843
    • Manley, S.1    Mucci, N.R.2    De Marzo, A.M.3    Rubin, M.A.4
  • 15
    • 0037846472 scopus 로고    scopus 로고
    • Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer
    • DR Rhodes MG Sanda AP Otte AM Chinnaiyan MA Rubin 2003 Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer J Natl Cancer Inst 95 661 668
    • (2003) J Natl Cancer Inst , vol.95 , pp. 661-668
    • Rhodes, D.R.1    Sanda, M.G.2    Otte, A.P.3    Chinnaiyan, A.M.4    Rubin, M.A.5
  • 16
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • CD Nobes A Hall 1995 Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 53 62
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 17
    • 0034729916 scopus 로고    scopus 로고
    • Rho GT Pases molecular switches that control the organization and dynamics of the actin cytoskeleton
    • A Hall CD Nobes 2000 Rho GT Pases molecular switches that control the organization and dynamics of the actin cytoskeleton Philos Trans R Soc Lond B Biol Sci 355 965 970
    • (2000) Philos Trans R Soc Lond B Biol Sci , vol.355 , pp. 965-970
    • Hall, A.1    Nobes, C.D.2
  • 18
    • 0029789678 scopus 로고    scopus 로고
    • The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
    • T Leung XQ Chen E Manser L Lim 1996 The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton Mol Cell Biol 16 5313 5327
    • (1996) Mol Cell Biol , vol.16 , pp. 5313-5327
    • Leung, T.1    Chen, X.Q.2    Manser, E.3    Lim, L.4
  • 20
    • 0242509224 scopus 로고    scopus 로고
    • ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix
    • MA Wozniak R Desai PA Solski CJ Der PJ Keely 2003 ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix J Cell Biol 163 583 595
    • (2003) J Cell Biol , vol.163 , pp. 583-595
    • Wozniak, M.A.1    Desai, R.2    Solski, P.A.3    Der, C.J.4    Keely, P.J.5
  • 22
    • 0038679226 scopus 로고    scopus 로고
    • Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
    • A Horiuchi T Imai C Wang S Ohira Y Feng T Nikaido I Konishi 2003 Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma Lab Invest 83 861 870
    • (2003) Lab Invest , vol.83 , pp. 861-870
    • Horiuchi, A.1    Imai, T.2    Wang, C.3    Ohira, S.4    Feng, Y.5    Nikaido, T.6    Konishi, I.7
  • 23
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer
    • T Kamai T Tsujii K Arai K Takagi H Asami Y Ito H Oshima 2003 Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer Clin Cancer Res 9 2632 2641
    • (2003) Clin Cancer Res , vol.9 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3    Takagi, K.4    Asami, H.5    Ito, Y.6    Oshima, H.7
  • 28
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • EA Clark TR Golub ES Lander RO Hynes 2000 Genomic analysis of metastasis reveals an essential role for RhoC Nature 406 532 535
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 29
    • 0038795117 scopus 로고    scopus 로고
    • Gene-expression profiling in human cutaneous melanoma
    • KM Carr M Bittner JM Trent 2003 Gene-expression profiling in human cutaneous melanoma Oncogene 22 3076 3080
    • (2003) Oncogene , vol.22 , pp. 3076-3080
    • Carr, K.M.1    Bittner, M.2    Trent, J.M.3
  • 30
    • 0031970317 scopus 로고    scopus 로고
    • Membrane association and targeting of prenylated Ras-like GTPases
    • MC Seabra 1998 Membrane association and targeting of prenylated Ras-like GTPases Cell Signal 10 167 172
    • (1998) Cell Signal , vol.10 , pp. 167-172
    • Seabra, M.C.1
  • 33
    • 0034630098 scopus 로고    scopus 로고
    • Recent advances in the study of prenylated proteins
    • M Sinensky 2000 Recent advances in the study of prenylated proteins Biochim Biophys Acta 1484 93 106
    • (2000) Biochim Biophys Acta , vol.1484 , pp. 93-106
    • Sinensky, M.1
  • 34
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Pt2
    • AL Bishop A Hall 2000 Rho GTPases and their effector proteins Biochem J 348 Pt2 241 255
    • (2000) Biochem J , vol.348 , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 37
    • 0028318136 scopus 로고
    • Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton
    • GC Prendergast JP Davide SJ deSolms EA Giuliani SL Graham JB Gibbs A Oliff NE Kohl 1994 Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton Mol Cell Biol 14 4193 4202
    • (1994) Mol Cell Biol , vol.14 , pp. 4193-4202
    • Prendergast, G.C.1    Davide, J.P.2    Desolms, S.J.3    Giuliani, E.A.4    Graham, S.L.5    Gibbs, J.B.6    Oliff, A.7    Kohl, N.E.8
  • 38
    • 0030916369 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB
    • PF Lebowitz PJ Casey GC Prendergast JA Thissen 1997 Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB J Biol Chem 272 15591 15594
    • (1997) J Biol Chem , vol.272 , pp. 15591-15594
    • Lebowitz, P.F.1    Casey, P.J.2    Prendergast, G.C.3    Thissen, J.A.4
  • 39
    • 0036599583 scopus 로고    scopus 로고
    • Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor
    • KL van Golen L Bao MM DiVito Z Wu GC Prendergast SD Merajver 2002 Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor Mol Cancer Ther 1 575 583
    • (2002) Mol Cancer Ther , vol.1 , pp. 575-583
    • Van Golen, K.L.1    Bao, L.2    Divito, M.M.3    Wu, Z.4    Prendergast, G.C.5    Merajver, S.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.