Fatigue versus activity-dependent fatigability in patients with central or peripheral motor impairments

Neurorehabilitation and Neural Repair

Volumn 22, Issue 2, 2008, Pages 105-110

  Dobkin, Bruce H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fatigue; Motor control; Muscle weakness; Neuropathy; Spinal cord injury; Spinal stenosis; Stroke

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; BRAIN FUNCTION; CLINICAL EXAMINATION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; FATIGUE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MOTOR DYSFUNCTION; MULTIPLE SCLEROSIS; MUSCLE TRAINING; MUSCLE WEAKNESS; MYASTHENIA GRAVIS; NONHUMAN; OCCUPATIONAL THERAPY; PHYSIOTHERAPY; REVIEW; SPINAL CORD INJURY; STROKE; VERTEBRAL CANAL STENOSIS;

EXERCISE THERAPY; EXERCISE TOLERANCE; FATIGUE SYNDROME, CHRONIC; HUMANS; MUSCLE FATIGUE; MUSCLE WEAKNESS; MUSCLE, SKELETAL; NERVOUS SYSTEM DISEASES; NEUROLOGIC EXAMINATION; NEUROMUSCULAR DISEASES;

EID: 39649089349     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968308315046     Document Type: Review

References (33)

1. de Groot M., Phillips S., Eskes G. Fatigue associated with stroke and other neurologic conditions: implications for stroke rehabilitation. Arch Phys Med Rehabil. 2003 ; 84: 1714-1720.
2. Mead G., Lynch J., Greig C., Young A., Lewis S., Sharpe M. Evaluation of fatigue scales in stroke patients. Stroke. 2007 ; 38: 2090-2095.
3. Kos D., Kerckhofs E., Nagels G., D'hooghe M, Ilsbroukx S. Origin of fatigue in multiple sclerosis: review. Neurorehabil Neural Repair. 2008 ; 22: 91-100.
4. Edwards DF, Hahn MG, Baum CM, Perlmutter MS, Sheedy C., Dromerick AW Screening patients with stroke for rehabilitation needs: validation of the post-stroke rehabilitation guidelines. Neurorehabil Neural Repair. 2006 ; 20: 42-48.
5. Sogaard K., Gandevia SC, Todd G., Petersen NT, Taylor JL The effect of sustained low-intensity contractions on supraspinal fatigue in human elbow flexor muscles. J Physiol. 2006 ; 573: 511-523.
6. Maluf KS, Enoka RM Task failure during fatiguing contractions performed by humans. J Appl Physiol. 2005 ; 99: 389-396.
7. Dobkin BH Underappreciated statin-induced myopathic weakness causes disability. Neurorehabil Neural Repair. 2005 ; 19: 259-263.
8. Gandevia SC Spinal and supraspinal factors in human muscle fatigue. Physiol Rev. 2001 ; 81: 1725-1789.
9. Miller RG Fatigue and therapeutic exercise. J Neurol Sci. 2006 ; 242 (1-2). 37-41.
10. Tartaglia M., Narayanan S., Francis S., et al. The relationship between diffuse axonal damage and fatigue in multiple sclerosis. Arch Neurol. 2004 ; 61: 201-207.
11. Gandevia SC, Taylor JL Supraspinal fatigue: the effects of caffeine on human muscle performance. J Appl Physiol. 2006 ; 100: 1749-1750.
12. Schillings ML, Stegeman DF, Zwarts MJ Determining central activation failure and peripheral fatigue in the course of sustained maximal voluntary contractions: a model-based approach. J Appl Physiol. 2005 ; 98: 2292-2297.
13. Schwid S., Thornton C., Pandya S. Quantitative assessment of motor fatigue and strength in MS. Neurology. 1999 ; 53: 743-750.
14. de Bode S., Mathern GW, Bookheimer S., Dobkin B. Locomotor training remodels fMRI sensorimotor cortical activations in children after cerebral hemispherectomy. Neurorehabil Neural Repair. 2007 ; 21: 497-508.
15. Ward NS, Newton JM, Swayne OB, et al. Motor system activation after subcortical stroke depends on corticospinal system integrity. Brain. 2006 ; 129 (Pt 3). 809-819.
16. Dettmers C., Lemon R., Stephan K., Fink G., Frackowiak R. Cerebral activation during the exertion of sustained static force in man. NeuroReport. 1996 ; 7: 2103-2110.
17. Liu JZ, Lewandowski B., Karakasis C., et al. Shifting of activation center in the brain during muscle fatigue: an explanation of minimal central fatigue ? Neuroimage. 2007 ; 35: 299-307.
18. Shibuya K., Kuboyama N. Human motor cortex oxygenation during exhaustive pinching task. Brain Res. 2007 ; 1156: 120-124.
19. Peltier SJ, Laconte SM, Niyazov DM, et al. Reductions in inter-hemispheric motor cortex functional connectivity after muscle fatigue. Brain Res. 2005 ; 1057 (1-2). 10-16.
20. Wittenberg G., Bastings E., Fowlkes A., Morgan T., Good D., Pons T. Dynamic course of intracortical TMS paired-pulse responses during recovery of motor function after stroke. Neurorehabil Neural Repair. 2007 ; 21: 568-573.
21. Dobkin BH Rehabilitation and functional neuroimaging dose-response trajectories for clinical trials. Neurorehabil Neural Repair. 2005 ; 19: 276-282.
22. Dobkin BH Confounders in rehabilitation trials of task-oriented training: lessons from the designs of the EXCITE and SCILT multicenter trials. Neurorehabil Neural Repair. 2007 ; 21: 3-13.
23. Dong Y., Winstein CJ, Albistegui-Dubois R., Dobkin BH Evolution of fMRI activation in perilesional primary motor cortex and cerebellum with rehabilitation training-related motor gains after stroke: a pilot study. Neurorehabil Neural Repair. 2007 ; 21 :PMID:17369516.
24. Dobkin B., Apple D., Barbeau H., et al. Methods for a randomized trial of weight-supported treadmill training versus conventional training for walking during inpatient rehabilitation after incomplete traumatic spinal cord injury. Neurorehabil Neural Repair. 2003 ; 17: 153-167.
25. Dobkin B., Barbeau H., Deforge D., et al. The evolution of walking-related outcomes over the first 12 weeks of rehabilitation for incomplete traumatic spinal cord injury: the multicenter randomized Spinal Cord Injury Locomotor Trial. Neurorehabil Neural Repair. 2007 ; 21: 25-35.
26. Dobkin BH, Apple D., Barbeau H., et al. Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI. Neurology. 2006 ; 66: 484-493.
27. Winstein C., Miller J., Blanton S., et al. Methods for a multi-site randomized trial to investigate the effect of constraint-induced movement therapy in improving upper extremity function among adults recovering from a cerebrovascular stroke. Neurorehabil Neural Repair. 2003 ; 17: 137-152.
28. Wolf SL, Winstein CJ, Miller JP, et al. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA. 2006 ; 296: 2095-2104.
29. Wolf SL, Thompson PA, Morris DM, et al. The EXCITE Trial: attributes of the Wolf Motor Function Test in patients with sub-acute stroke. Neurorehabil Neural Repair. 2005 ; 19: 194-205.
30. Dobkin B. Rehabilitation after stroke. N Engl J Med. 2005 ; 352: 1677-1684.
31. Ziemann U., Meintzschel F., Korchounov A., Ilic TV Pharmacological modulation of plasticity in the human motor cortex. Neurorehabil Neural Repair. 2006 ; 20: 243-251.
32. Barbay S., Zoubina EV, Dancause N., et al. A single injection of d-amphetamine facilitates improvements in motor training following a focal cortical infarct in squirrel monkeys. Neurorehabil Neural Repair. 2006 ; 20: 455-458.
33. MacDonald E., Van der Lee H., Pocock D., Cole C., Thomas N., Kleim J. A novel phosphodiesterase type 4 inhibitor HT-0712, enhances rehabilitation- dependent motor recovery and cortical reorganization after focal cortical ischemia. Neurorehabil Neural Repair. 2007 ; 21: 486-496.