A novel phosphodiesterase type 4 inhibitor, HT-0712, enhances rehabilitation-dependent motor recovery and cortical reorganization after focal cortical ischemia

Neurorehabilitation and Neural Repair

Volumn 21, Issue 6, 2007, Pages 486-496

  MacDonald, Erin ^a   Van Der Lee, Heidi ^a   Pocock, David ^a   Cole, Christy ^a   Thomas, Nagheme ^a,c   VandenBerg, Penny M ^a   Bourtchouladze, Rusiko ^b   Kleim, Jeffrey A ^a,c,d  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

^b Helicon Therapeutics Inc   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cerebral ischemia; Cortical plasticity; Motor recovery; Phosphodiesterase type 4 inhibitor; Rehabilitation

Indexed keywords

CYCLIC AMP; HT 0712; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN ISCHEMIA; BRAIN MAPPING; COGNITION; CONTROLLED STUDY; DRUG MECHANISM; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NONHUMAN; RAT;

ANIMALS; BRAIN ISCHEMIA; BRAIN MAPPING; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; FORELIMB; MALE; MOTOR CORTEX; MOTOR NEURONS; NEURONAL PLASTICITY; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION;

EID: 35348906041     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968307305521     Document Type: Article

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