-
1
-
-
3543078012
-
HIV and SIV CTL escape: Implications for vaccine design
-
Goulder PJ and Watkins DI: HIV and SIV CTL escape: Implications for vaccine design. Nat Rev Immunol 2004;4:630-640.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 630-640
-
-
Goulder, P.J.1
Watkins, D.I.2
-
2
-
-
0035198096
-
Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: Relationship to viral load in untreated HIV infection
-
Betts MR, Ambrozak DR, Douek DC, et al.: Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: Relationship to viral load in untreated HIV infection. J Virol 2001;75:11983-11991.
-
(2001)
J Virol
, vol.75
, pp. 11983-11991
-
-
Betts, M.R.1
Ambrozak, D.R.2
Douek, D.C.3
-
3
-
-
0037302428
-
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific Tcell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
-
Addo MM, Yu XG, Rathod A, et al.: Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific Tcell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol 2003;77:2081-2092.
-
(2003)
J Virol
, vol.77
, pp. 2081-2092
-
-
Addo, M.M.1
Yu, X.G.2
Rathod, A.3
-
4
-
-
0034684666
-
Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children
-
Goulder PJ, Tang Y, Brander C, et al.: Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children. J Exp Med 2000;192:1819-1832.
-
(2000)
J Exp Med
, vol.192
, pp. 1819-1832
-
-
Goulder, P.J.1
Tang, Y.2
Brander, C.3
-
5
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
-
Betts MR, Nason MC, West SM, et al.: HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 2006;107:4781-4789.
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
-
6
-
-
0034600786
-
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
-
Appay V, Nixon DF, Donahoe SM, et al.: HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med 2000;192:63-75.
-
(2000)
J Exp Med
, vol.192
, pp. 63-75
-
-
Appay, V.1
Nixon, D.F.2
Donahoe, S.M.3
-
7
-
-
0033771293
-
A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon
-
Goepfert PA, Bansal A, Edwards BH, et al.: A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon. J Virol 2000;74:10249-10255.
-
(2000)
J Virol
, vol.74
, pp. 10249-10255
-
-
Goepfert, P.A.1
Bansal, A.2
Edwards, B.H.3
-
8
-
-
0035077083
-
High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: Evidence for impaired CTL effector function
-
Kostense S, Ogg GS, Manting EH, et al.: High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: Evidence for impaired CTL effector function. Eur J Immunol 2001;31:677-686.
-
(2001)
Eur J Immunol
, vol.31
, pp. 677-686
-
-
Kostense, S.1
Ogg, G.S.2
Manting, E.H.3
-
9
-
-
0034330698
-
Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection
-
Shankar P, Russo M, Harnisch B, Patterson M, Skolnik P, and Lieberman J: Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection. Blood 2000;96:3094-3101.
-
(2000)
Blood
, vol.96
, pp. 3094-3101
-
-
Shankar, P.1
Russo, M.2
Harnisch, B.3
Patterson, M.4
Skolnik, P.5
Lieberman, J.6
-
10
-
-
0035282444
-
Skewed maturation of memory HIV-specific CD8 T lymphocytes
-
Champagne P, Ogg GS, King AS, et al.: Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001;410:106-111.
-
(2001)
Nature
, vol.410
, pp. 106-111
-
-
Champagne, P.1
Ogg, G.S.2
King, A.S.3
-
11
-
-
0027985211
-
Presence of multiple genetic subtypes of human immunodeficiency virus type 1 proviruses in Uganda
-
Bruce C, Clegg JC, Featherstone A, et al.: Presence of multiple genetic subtypes of human immunodeficiency virus type 1 proviruses in Uganda. AIDS Res Hum Retroviruses 1994;10:1543-1550.
-
(1994)
AIDS Res Hum Retroviruses
, vol.10
, pp. 1543-1550
-
-
Bruce, C.1
Clegg, J.C.2
Featherstone, A.3
-
12
-
-
0037131204
-
Detection of HIV-1 subtypes, recombinants, and dual infections in east Africa by a multi-region hybridization assay
-
Hoelscher M, Dowling WE, Sanders-Buell E, et al.: Detection of HIV-1 subtypes, recombinants, and dual infections in east Africa by a multi-region hybridization assay. AIDS 2002;16:2055-2064.
-
(2002)
AIDS
, vol.16
, pp. 2055-2064
-
-
Hoelscher, M.1
Dowling, W.E.2
Sanders-Buell, E.3
-
13
-
-
13344278708
-
The emergeing genetic diversity of HIV. The importance of global surveillance for diagnostics, research and prevention
-
Hu DJ, Dondero TJ, Rayfield MA, et al.: The emergeing genetic diversity of HIV. The importance of global surveillance for diagnostics, research and prevention. JAMA 1996;275:210-216.
-
(1996)
JAMA
, vol.275
, pp. 210-216
-
-
Hu, D.J.1
Dondero, T.J.2
Rayfield, M.A.3
-
14
-
-
0035895662
-
Relationship between HIV-1 Env subtypes A and D and disease progression in a rural Ugandan cohort
-
Kaleebu P, Ross A, Morgan D, et al.: Relationship between HIV-1 Env subtypes A and D and disease progression in a rural Ugandan cohort. AIDS 2001;15:293-299.
-
(2001)
AIDS
, vol.15
, pp. 293-299
-
-
Kaleebu, P.1
Ross, A.2
Morgan, D.3
-
15
-
-
0036569329
-
Effect of human immunodeficiency virus (HIV) type 1 envelope subtypes A and D on disease progression in a large cohort of HIV-1-positive persons in Uganda
-
Kaleebu P, French N, Mahe C, et al.: Effect of human immunodeficiency virus (HIV) type 1 envelope subtypes A and D on disease progression in a large cohort of HIV-1-positive persons in Uganda. J Infect Dis 2002;185:1244-1250.
-
(2002)
J Infect Dis
, vol.185
, pp. 1244-1250
-
-
Kaleebu, P.1
French, N.2
Mahe, C.3
-
16
-
-
2342464173
-
High prevalence of antiretroviral resistance in treated Ugandans infected with non-subtype B human immunodeficiency virus type 1
-
Richard N, Juntilla M, Abraha A, et al.: High prevalence of antiretroviral resistance in treated Ugandans infected with non-subtype B human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 2004;20:355-364.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 355-364
-
-
Richard, N.1
Juntilla, M.2
Abraha, A.3
-
17
-
-
33644840404
-
Different rates of disease progression of HIV type 1 infection in Tanzania based on infecting subtype
-
Vasan A, Renjifo B, Hertzmark E, et al.: Different rates of disease progression of HIV type 1 infection in Tanzania based on infecting subtype. Clin Infect Dis 2006;42:843-852.
-
(2006)
Clin Infect Dis
, vol.42
, pp. 843-852
-
-
Vasan, A.1
Renjifo, B.2
Hertzmark, E.3
-
18
-
-
34047207715
-
HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads
-
Baeten JM, Chohan B, Lavreys L, et al.: HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads. J Infect Dis 2007;195:1177-1180.
-
(2007)
J Infect Dis
, vol.195
, pp. 1177-1180
-
-
Baeten, J.M.1
Chohan, B.2
Lavreys, L.3
-
19
-
-
15444363618
-
Depletion of regulatory T cells in HIV infection is associated with immune activation
-
Eggena MP, Barugahare B, Jones N, et al.: Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005;174:4407-4414.
-
(2005)
J Immunol
, vol.174
, pp. 4407-4414
-
-
Eggena, M.P.1
Barugahare, B.2
Jones, N.3
-
20
-
-
13944252473
-
T cell activation in HIV-seropositive Ugandans: Differential associations with viral load, CD4+ T cell depletion, and coinfection
-
Eggena MP, Barugahare B, Okello M, et al.: T cell activation in HIV-seropositive Ugandans: Differential associations with viral load, CD4+ T cell depletion, and coinfection. J Infect Dis 2005;191:694-701.
-
(2005)
J Infect Dis
, vol.191
, pp. 694-701
-
-
Eggena, M.P.1
Barugahare, B.2
Okello, M.3
-
21
-
-
33846205655
-
Presence of distinct subsets of cytolytic CD8+ T cells in chronic HIV infection
-
Jones N, Eggena M, Baker C, et al.: Presence of distinct subsets of cytolytic CD8+ T cells in chronic HIV infection. AIDS Res Hum Retroviruses 2006;22:1007-1013.
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 1007-1013
-
-
Jones, N.1
Eggena, M.2
Baker, C.3
-
22
-
-
20144372216
-
Human immunodeficiency virus-specific responses in adult Ugandans: Patterns of cross-clade recognition
-
Barugahare B, Baker C, K'Aluoch O, et al.: Human immunodeficiency virus-specific responses in adult Ugandans: Patterns of cross-clade recognition. J Virol 2005;79:4132-4139.
-
(2005)
J Virol
, vol.79
, pp. 4132-4139
-
-
Barugahare, B.1
Baker, C.2
K'Aluoch, O.3
-
23
-
-
0025905925
-
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
-
Peters PJ, Borst J, Oorschot V, et al.: Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med 1991;173:1099-1109.
-
(1991)
J Exp Med
, vol.173
, pp. 1099-1109
-
-
Peters, P.J.1
Borst, J.2
Oorschot, V.3
-
24
-
-
0036595397
-
Cytotoxic T lymphocytes: All roads lead to death
-
Barry M and Bleackley RC: Cytotoxic T lymphocytes: All roads lead to death. Nat Rev Immunol 2002;2:401-409.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 401-409
-
-
Barry, M.1
Bleackley, R.C.2
-
25
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
Betts MR, Brenchley JM, Price DA, et al.: Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003;281:65-78.
-
(2003)
J Immunol Methods
, vol.281
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
-
26
-
-
2442500442
-
The functional profile of primary human antiviral CD8 T cell effector activity is dictated by cognate peptide concentration
-
Betts MR, Price DA, Brenchley JM, et al.: The functional profile of primary human antiviral CD8 T cell effector activity is dictated by cognate peptide concentration. J Immunol 2004;172:6407-6417.
-
(2004)
J Immunol
, vol.172
, pp. 6407-6417
-
-
Betts, M.R.1
Price, D.A.2
Brenchley, J.M.3
-
27
-
-
34249711903
-
PD-1 upregulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors, but not in long-term non-progressors
-
Zhang JY, Zhang Z, Wang X, et al.: PD-1 upregulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors, but not in long-term non-progressors. Blood 2007;109:4671-4678.
-
(2007)
Blood
, vol.109
, pp. 4671-4678
-
-
Zhang, J.Y.1
Zhang, Z.2
Wang, X.3
-
28
-
-
33749009709
-
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
-
Trautmann L, Janbazian L, Chomont N, et al.: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 2006;12:1198-1202.
-
(2006)
Nat Med
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
-
29
-
-
0037225837
-
Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection
-
Novitsky V, Gilbert P, Peter T, et al.: Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection. J Virol 2003;77:882-890.
-
(2003)
J Virol
, vol.77
, pp. 882-890
-
-
Novitsky, V.1
Gilbert, P.2
Peter, T.3
-
30
-
-
10744226946
-
Consistent cytotoxic-Tlymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities
-
Frahm N, Korber BT, Adams CM, et al.: Consistent cytotoxic-Tlymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol 2004;78:2187-2200.
-
(2004)
J Virol
, vol.78
, pp. 2187-2200
-
-
Frahm, N.1
Korber, B.T.2
Adams, C.M.3
-
31
-
-
0036171258
-
Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma
-
Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, and Goepfert PA: Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J Virol 2002;76:2298-2305.
-
(2002)
J Virol
, vol.76
, pp. 2298-2305
-
-
Edwards, B.H.1
Bansal, A.2
Sabbaj, S.3
Bakari, J.4
Mulligan, M.J.5
Goepfert, P.A.6
-
32
-
-
0034661671
-
Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors
-
Gea-Banacloche JC, Migueles SA, Martino L, et al.: Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors. J Immunol 2000;165:1082-1092.
-
(2000)
J Immunol
, vol.165
, pp. 1082-1092
-
-
Gea-Banacloche, J.C.1
Migueles, S.A.2
Martino, L.3
-
33
-
-
0033791350
-
Cellular immunity to HIV-1 clades: Relevance to HIV-1 vaccine trials in Uganda
-
Cao H, Mani I, Vincent R, et al.: Cellular immunity to HIV-1 clades: Relevance to HIV-1 vaccine trials in Uganda. J Infect Dis 2000;182:1350-1356.
-
(2000)
J Infect Dis
, vol.182
, pp. 1350-1356
-
-
Cao, H.1
Mani, I.2
Vincent, R.3
-
34
-
-
0037374385
-
Evaluation of antigen-specific responses using in vitro enriched T cells
-
Jones N, Agrawal D, Elrefaei M, et al.: Evaluation of antigen-specific responses using in vitro enriched T cells. J Immunol Methods 2003;274:139-147.
-
(2003)
J Immunol Methods
, vol.274
, pp. 139-147
-
-
Jones, N.1
Agrawal, D.2
Elrefaei, M.3
|