Lipoxygenase reaction mechanism: Demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover

Biochemistry

Volumn 35, Issue 39, 1996, Pages 12882-12892

  Glickman, Michael H ^a,b   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; LINOLEIC ACID; LIPOXYGENASE; OXYGEN; TRITIUM OXIDE;

ARTICLE; COVALENT BOND; ENZYME BINDING; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; ISOTOPE LABELING; LIPID PEROXIDATION; MICHAELIS MENTEN KINETICS; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REACTION ANALYSIS; SOYBEAN; SPECTROPHOTOMETRY; STEADY STATE;

CATALYSIS; DEUTERIUM; FREE RADICALS; HYDROGEN; KINETICS; LINOLEIC ACID; LINOLEIC ACIDS; LIPID PEROXIDES; LIPOXYGENASE; MODELS, CHEMICAL; OXYGEN; PROTEIN BINDING; SOYBEANS;

GLYCINE MAX; TRITIUM;

EID: 0029843150     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960985q     Document Type: Article

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