Endocrine and antineoplastic actions of growth hormone-releasing hormone antagonists

Current Medicinal Chemistry

Volumn 15, Issue 4, 2008, Pages 314-321

  Kovács, Magdolna ^a   Schally, Andrew V ^b,c   Varga, József L ^b,c   Zarándi, Márta ^b,c,d  

^a UNIVERSITY OF PÉCS   (Hungary)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Antagonistic analogs; Anti cancer; Cell proliferation; Growth hormone (GH); Inhibition; Insulin like growth factor (IGF); Oncogene; Tumor growth

Indexed keywords

1 NAPHTHYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE 29 AGMATINE]GROWTH HORMONE RELEASING HORMONE(1-29); ACETYL[1 TYROSINE DEXTRO 2 ARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; ADENOVIRUS VECTOR; BOMBESIN; CYCLIC AMP; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING FACTOR ANTAGONIST; GROWTH HORMONE RELEASING FACTOR DERIVATIVE; GROWTH HORMONE RELEASING FACTOR RECEPTOR; HORMONE ANTAGONIST; ISOBUTYRYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINEL 29 AGMATINE]GROWTH HORMONE RELEASING HORMONE(1-29); JV 1 36; JV 1 38; JV 1 62; JV 1 63; JV 1 65; JV 7 72; JV V 74; LIPOPEPTIDE; MITOGENIC AGENT; MZ 4 243; MZ 4 71; MZ 5 156; MZ 6 55; MZ J 7 74; PEPTIDE DERIVATIVE; PEPTIDE HORMONE ANTAGONIST; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE 29 AGMATINE]GROWTH HORMONE RELEASING HORMONE(1-29); PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 8 CITRULLININE 9 ARGININE 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 (4 AMIDINOPHENYLALANINE) 10 METHYLTYROSINE 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 ARGININE 10 (4 AMIDINOPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 ARGININE 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 CITRULLININE 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 HOMOARGININE 10 (4 AMIDINOPHENYLALANINE) 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PHENYLACETYL[1 TYROSINE DEXTRO 2 ARGININE 6 (4 CHLOROPHENYLALANINE) 9 HOMOARGININE 10 METHYLTYROSINE 15 (2 AMINOBUTYRIC ACID) 27 NORLEUCINE DEXTRO 28 ARGININE 29 HOMOARGININE]GROWTH HORMONE RELEASING HORMONE(1-29)AMIDE; PROTEIN DERIVATIVE; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACROMEGALY; ANTINEOPLASTIC ACTIVITY; AUTOCRINE EFFECT; CANCER INHIBITION; CANCER THERAPY; CELL PROLIFERATION; DRUG DESIGN; DRUG MECHANISM; DRUG MEGADOSE; DRUG STRUCTURE; ENDOCRINE DISEASE; GENE OVEREXPRESSION; HORMONE INHIBITION; HUMAN; HYPOPHYSIS TUMOR; LOW DRUG DOSE; NONHUMAN; REVIEW; TRANSGENIC MOUSE; TUMOR CELL; TUMOR CELL LINE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; ENDOCRINE GLANDS; GROWTH HORMONE-RELEASING HORMONE; HUMANS;

EID: 39449110906     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708783497355     Document Type: Review

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