Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 39, 2006, Pages 14513-14518

  Hohla, Florian ^a,d   Schally, Andrew V ^a,b,c   Szepeshazi, Karoly ^a,b   Varga, Jozsef L ^a   Buchholz, Stefan ^a   Köster, Frank ^a   Heinrich, Elmar ^a   Halmos, Gabor ^a,c   Rick, Ferenc G ^a   Kannadka, Chandrika ^a   Datz, Christian ^d   Kanashiro, Celia A ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Chemotherapeutic substance; Cyclooxygenase 2; K Ras; Non small cell lung cancer; pAkt

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; DOCETAXEL; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING FACTOR RECEPTOR; HORMONE ANTAGONIST; JV 1 92; K RAS PROTEIN; MESSENGER RNA; MZ J 7 138; PROTEIN; PROTEIN KINASE B; SOMATOMEDIN C; SPLICE VARIANT 1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; DRUG TREATMENT FAILURE; FEMALE; HUMAN; HUMAN CELL; LUNG CARCINOMA; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; TUMOR VOLUME; TUMOR XENOGRAFT;

ALTERNATIVE SPLICING; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BODY WEIGHT; CARCINOMA, NON-SMALL-CELL LUNG; CELL PROLIFERATION; CYCLOOXYGENASE 2; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH HORMONE-RELEASING HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, NUDE; ORGAN SIZE; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS P21(RAS); RADIOIMMUNOASSAY; RECEPTORS, NEUROPEPTIDE; RECEPTORS, PITUITARY HORMONE-REGULATING HORMONE; RNA, MESSENGER; TAXOIDS; TRANSPLANTATION, HETEROLOGOUS;

MUS MUSCULUS;

EID: 33749252356     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0605309103     Document Type: Article

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