-
1
-
-
0023200595
-
The incidence of multifocal cerebral gliomas: A histologic study of large hemisphere sections
-
Barnard RO, Geddes JF. The incidence of multifocal cerebral gliomas: a histologic study of large hemisphere sections. Cancer. 1987;60:1519-1531.
-
(1987)
Cancer
, vol.60
, pp. 1519-1531
-
-
Barnard, R.O.1
Geddes, J.F.2
-
2
-
-
0025877114
-
The cause of death in patients with glioblastoma is multifactorial: Clinical factors and autopsy findings in 117 cases of supratentorial glioblastoma in adults
-
Silbergeld DL, Rostomily RC, Alvord EC Jr. The cause of death in patients with glioblastoma is multifactorial: clinical factors and autopsy findings in 117 cases of supratentorial glioblastoma in adults. J Neurooncol. 1991;10:179-185.
-
(1991)
J Neurooncol
, vol.10
, pp. 179-185
-
-
Silbergeld, D.L.1
Rostomily, R.C.2
Alvord Jr., E.C.3
-
3
-
-
0024376302
-
Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma
-
Wallner KE, Galicich JH, Krol G, et al. Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma. Int J Radiat Oncol Biol Phys. 1989;16:1405-1409.
-
(1989)
Int J Radiat Oncol Biol Phys
, vol.16
, pp. 1405-1409
-
-
Wallner, K.E.1
Galicich, J.H.2
Krol, G.3
-
5
-
-
0038179723
-
Cost of migration: Invasion of malignant gliomas and implications for treatment
-
Giese A, Bjerkvig R, Berens ME, et al. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol. 2003;21:1624-1636.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1624-1636
-
-
Giese, A.1
Bjerkvig, R.2
Berens, M.E.3
-
6
-
-
0032814773
-
Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses
-
Ikeda K, Ichikawa T, Wakimoto H, et al. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nat Med. 1999;5:881-887.
-
(1999)
Nat Med
, vol.5
, pp. 881-887
-
-
Ikeda, K.1
Ichikawa, T.2
Wakimoto, H.3
-
7
-
-
0033997183
-
Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication- conditional herpes simplex virus mutant
-
Ikeda K, Wakimoto H, Ichikawa T, et al. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication- conditional herpes simplex virus mutant. J Virol. 2000;74:4765-4775.
-
(2000)
J Virol
, vol.74
, pp. 4765-4775
-
-
Ikeda, K.1
Wakimoto, H.2
Ichikawa, T.3
-
8
-
-
0029818276
-
Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment
-
Kramm CM, Rainov NG, Sena-Esteves M, et al. Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment. Hum Gene Ther. 1996;7:1989-1994.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1989-1994
-
-
Kramm, C.M.1
Rainov, N.G.2
Sena-Esteves, M.3
-
9
-
-
0030065355
-
Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors
-
Kramm CM, Rainov NG, Sena-Esteves M, et al. Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors. Hum Gene Ther. 1996;7:291-300.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 291-300
-
-
Kramm, C.M.1
Rainov, N.G.2
Sena-Esteves, M.3
-
10
-
-
17644407319
-
Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain
-
Liu R, Martuza RL, Rabkin SD. Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain. Gene Ther. 2005;12:647-654.
-
(2005)
Gene Ther
, vol.12
, pp. 647-654
-
-
Liu, R.1
Martuza, R.L.2
Rabkin, S.D.3
-
11
-
-
1842486876
-
Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
-
Furumoto K, Soares L, Engleman EG, et al. Induction of potent antitumor immunity by in situ targeting of intratumoral DCs. J Clin Invest. 2004;113:774-783.
-
(2004)
J Clin Invest
, vol.113
, pp. 774-783
-
-
Furumoto, K.1
Soares, L.2
Engleman, E.G.3
-
12
-
-
17144417748
-
Dendritic cells as therapeutic vaccines against cancer
-
Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol. 2005;5:296-306.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 296-306
-
-
Banchereau, J.1
Palucka, A.K.2
-
13
-
-
10344240632
-
Dendritic cells and immune responses in the central nervous system
-
Lowenstein PR. Dendritic cells and immune responses in the central nervous system. Trends Immunol. 2002;23:70.
-
(2002)
Trends Immunol
, vol.23
, pp. 70
-
-
Lowenstein, P.R.1
-
14
-
-
0041562478
-
MART-1 adenovirus-transduced dendritic cell immunization in a murine model of metastatic central nervous system tumor
-
Broder H, Anderson A, Kremen TJ, et al. MART-1 adenovirus-transduced dendritic cell immunization in a murine model of metastatic central nervous system tumor. J Neurooncol. 2003;64:21-30.
-
(2003)
J Neurooncol
, vol.64
, pp. 21-30
-
-
Broder, H.1
Anderson, A.2
Kremen, T.J.3
-
15
-
-
0033007570
-
Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens
-
Liau LM, Black KL, Prins RM, et al. Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens. J Neurosurg. 1999;90:1115-1124.
-
(1999)
J Neurosurg
, vol.90
, pp. 1115-1124
-
-
Liau, L.M.1
Black, K.L.2
Prins, R.M.3
-
16
-
-
23044479028
-
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
-
Liau LM, Prins RM, Kiertscher SM, et al. Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res. 2005;11:5515-5525.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5515-5525
-
-
Liau, L.M.1
Prins, R.M.2
Kiertscher, S.M.3
-
17
-
-
0142057729
-
Dendritic cell-based glioma immunotherapy (review)
-
Yamanaka R, Yajima N, Abe T, et al. Dendritic cell-based glioma immunotherapy (review). Int J Oncol. 2003;23:5-15.
-
(2003)
Int J Oncol
, vol.23
, pp. 5-15
-
-
Yamanaka, R.1
Yajima, N.2
Abe, T.3
-
18
-
-
3142692559
-
Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma
-
Yu JS, Liu G, Ying H, et al. Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma. Cancer Res. 2004;64:4973-4979.
-
(2004)
Cancer Res
, vol.64
, pp. 4973-4979
-
-
Yu, J.S.1
Liu, G.2
Ying, H.3
-
19
-
-
33644836881
-
FMS-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain
-
Curtin JF, King GD, Barcia C, et al. FMS-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J Immunol. 2006;176:3566-3577
-
(2006)
J Immunol
, vol.176
, pp. 3566-3577
-
-
Curtin, J.F.1
King, G.D.2
Barcia, C.3
-
20
-
-
0029661945
-
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified
-
Maraskovsky E, Brasel K, Teepe M, et al. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J Exp Med. 1996;184:1953-1962.
-
(1996)
J Exp Med
, vol.184
, pp. 1953-1962
-
-
Maraskovsky, E.1
Brasel, K.2
Teepe, M.3
-
21
-
-
0031214007
-
FLT3 ligand induces the generation of functionally active dendritic cells in mice
-
Shurin MR, Pandharipande PP, Zorina TD, et al. FLT3 ligand induces the generation of functionally active dendritic cells in mice. Cell Immunol. 1997;179:174-184.
-
(1997)
Cell Immunol
, vol.179
, pp. 174-184
-
-
Shurin, M.R.1
Pandharipande, P.P.2
Zorina, T.D.3
-
22
-
-
0032530754
-
Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: Implications for anti-cancer and anti-viral therapy
-
Shaw SG, Maung AA, Steptoe RJ, et al. Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: implications for anti-cancer and anti-viral therapy. J Immunol. 1998;161:2817-2824.
-
(1998)
J Immunol
, vol.161
, pp. 2817-2824
-
-
Shaw, S.G.1
Maung, A.A.2
Steptoe, R.J.3
-
23
-
-
0036137957
-
Antitumor effects of Flt3 ligand in transplanted murine tumor models
-
Averbook BJ, Schuh JL, Papay R, et al. Antitumor effects of Flt3 ligand in transplanted murine tumor models. J Immunother. 2002;25:27-35.
-
(2002)
J Immunother
, vol.25
, pp. 27-35
-
-
Averbook, B.J.1
Schuh, J.L.2
Papay, R.3
-
24
-
-
14444284333
-
Antitumor activity and immunotherapeutic properties of Flt3-ligand in a murine breast cancer model
-
Chen K, Braun S, Lyman S, et al. Antitumor activity and immunotherapeutic properties of Flt3-ligand in a murine breast cancer model. Cancer Res. 1997;57:3511-3516.
-
(1997)
Cancer Res
, vol.57
, pp. 3511-3516
-
-
Chen, K.1
Braun, S.2
Lyman, S.3
-
25
-
-
0034073233
-
Antileukemic activity of Flt3 ligand in murine leukemia
-
Wang A, Braun SE, Sonpavde G, et al. Antileukemic activity of Flt3 ligand in murine leukemia. Cancer Res. 2000;60:1895-1900.
-
(2000)
Cancer Res
, vol.60
, pp. 1895-1900
-
-
Wang, A.1
Braun, S.E.2
Sonpavde, G.3
-
26
-
-
0033179610
-
Synergistic action of FMS-like tyrosine kinase 3 ligand and CD40 ligand in the induction of dendritic cells and generation of antitumor immunity in vivo
-
Borges L, Miller RE, Jones J, et al. Synergistic action of FMS-like tyrosine kinase 3 ligand and CD40 ligand in the induction of dendritic cells and generation of antitumor immunity in vivo. J Immunol. 1999;163:1289-1297.
-
(1999)
J Immunol
, vol.163
, pp. 1289-1297
-
-
Borges, L.1
Miller, R.E.2
Jones, J.3
-
27
-
-
0030952766
-
Flt3 ligand induces tumor regression and antitumor immune responses in vivo
-
Lynch DH, Andreasen A, Maraskovsky E, et al. Flt3 ligand induces tumor regression and antitumor immune responses in vivo. Nat Med. 1997;3:625-631.
-
(1997)
Nat Med
, vol.3
, pp. 625-631
-
-
Lynch, D.H.1
Andreasen, A.2
Maraskovsky, E.3
-
28
-
-
0032403456
-
FLT3-ligand administration inhibits liver metastases: Role of NK cells
-
Peron JM, Esche C, Subbotin VM, et al. FLT3-ligand administration inhibits liver metastases: role of NK cells. J Immunol. 1998;161:6164-6170.
-
(1998)
J Immunol
, vol.161
, pp. 6164-6170
-
-
Peron, J.M.1
Esche, C.2
Subbotin, V.M.3
-
29
-
-
10344265483
-
Inflammatory and anti-glioma effects of an adenovirus expressing human soluble FMS-like tyrosine kinase 3 ligand (hsFlt3L): Treatment with hsFlt3L inhibits intracranial glioma progression
-
Ali S, Curtin JF, Zirger JM, et al. Inflammatory and anti-glioma effects of an adenovirus expressing human soluble FMS-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Mol Ther. 2004;10:1071-1084.
-
(2004)
Mol Ther
, vol.10
, pp. 1071-1084
-
-
Ali, S.1
Curtin, J.F.2
Zirger, J.M.3
-
30
-
-
23844482747
-
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model
-
Ali S, King GD, Curtin JF, et al. Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Res. 2005;65:7194-7204.
-
(2005)
Cancer Res
, vol.65
, pp. 7194-7204
-
-
Ali, S.1
King, G.D.2
Curtin, J.F.3
-
31
-
-
33747068747
-
Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells
-
Candolfi M, Curtin JF, Xiong WD, et al. Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells. Mol Ther. 2006;14:371-381.
-
(2006)
Mol Ther
, vol.14
, pp. 371-381
-
-
Candolfi, M.1
Curtin, J.F.2
Xiong, W.D.3
-
32
-
-
0034860482
-
Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU
-
Maleniak TC, Darling JL, Lowenstein PR, et al. Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU. Cancer Gene Ther. 2001;8:589-598.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 589-598
-
-
Maleniak, T.C.1
Darling, J.L.2
Lowenstein, P.R.3
-
33
-
-
35449004503
-
Intracranial glioblastoma models in preclinical neuro-oncology: Neuropathological characterization and tumor progression
-
Candolfi M, Curtin JF, Nichols WS, et al. Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. J Neurooncol. 2007; 85:133-48.
-
(2007)
J Neurooncol
, vol.85
, pp. 133-148
-
-
Candolfi, M.1
Curtin, J.F.2
Nichols, W.S.3
-
34
-
-
39149143149
-
-
Southgate T, Kingston P, Castro MG. Gene transfer into neural cells in vivo using adenoviral vectors. In: Gerfen CR, McKay R, Rogawski MA, Sibley DR, Skolnick P, eds. Current Protocols in Neuroscience. New York: John Wiley; 2000:4.23.1-4.23.40.
-
Southgate T, Kingston P, Castro MG. Gene transfer into neural cells in vivo using adenoviral vectors. In: Gerfen CR, McKay R, Rogawski MA, Sibley DR, Skolnick P, eds. Current Protocols in Neuroscience. New York: John Wiley; 2000:4.23.1-4.23.40.
-
-
-
-
35
-
-
0032741719
-
Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials
-
Dewey RA, Morrissey G, Cowsill CM, et al. Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials. Nat Med. 1999;5:1256-1263.
-
(1999)
Nat Med
, vol.5
, pp. 1256-1263
-
-
Dewey, R.A.1
Morrissey, G.2
Cowsill, C.M.3
-
36
-
-
0034691208
-
Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases
-
Thomas CE, Schiedner G, Kochanek S, et al. Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic diseases. Proc Natl Acad Sci USA. 2000;97:7482-7487
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7482-7487
-
-
Thomas, C.E.1
Schiedner, G.2
Kochanek, S.3
-
37
-
-
0346872991
-
Improved system for helper-dependent adenoviral vector production
-
Palmer D, Ng P. Improved system for helper-dependent adenoviral vector production. Mol Ther. 2003;8:846-852.
-
(2003)
Mol Ther
, vol.8
, pp. 846-852
-
-
Palmer, D.1
Ng, P.2
-
38
-
-
0029981799
-
Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks
-
Dion LD, Fang J, Garver RI Jr. Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks. J Virol Methods. 1996;56:99-107
-
(1996)
J Virol Methods
, vol.56
, pp. 99-107
-
-
Dion, L.D.1
Fang, J.2
Garver Jr., R.I.3
-
39
-
-
0028466386
-
Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus
-
Cotten M, Baker A, Saltik M, et al. Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus. Gene Ther. 1994;1:239-246.
-
(1994)
Gene Ther
, vol.1
, pp. 239-246
-
-
Cotten, M.1
Baker, A.2
Saltik, M.3
-
40
-
-
0014329310
-
The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12
-
Maizel JV Jr, White DO, Scharff MD. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology. 1968;36:115-125.
-
(1968)
Virology
, vol.36
, pp. 115-125
-
-
Maizel Jr, J.V.1
White, D.O.2
Scharff, M.D.3
-
41
-
-
33646921996
-
Quantification of high-capacity helper-dependent adenoviral vector genomes in vitro and in vivo, using quantitative TaqMan real-time polymerase chain reaction
-
Puntel M, Curtin JF, Zirger JM, et al. Quantification of high-capacity helper-dependent adenoviral vector genomes in vitro and in vivo, using quantitative TaqMan real-time polymerase chain reaction. Hum Gene Ther. 2006;17:531-544.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 531-544
-
-
Puntel, M.1
Curtin, J.F.2
Zirger, J.M.3
-
42
-
-
0036370360
-
High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain
-
Lowenstein PR, Thomas CE, Umana P, et al. High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain. Methods Enzymol. 2002;346:292-311.
-
(2002)
Methods Enzymol
, vol.346
, pp. 292-311
-
-
Lowenstein, P.R.1
Thomas, C.E.2
Umana, P.3
-
43
-
-
0035005627
-
Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination
-
Umana P, Gerdes CA, Stone D, et al. Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination. Nat Biotechnol. 2001;19:582-585.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 582-585
-
-
Umana, P.1
Gerdes, C.A.2
Stone, D.3
-
44
-
-
33846190210
-
Adenoviral-mediated gene transfer into the canine brain in vivo
-
Candolfi M, Kroeger KM, Pluhar GE, et al. Adenoviral-mediated gene transfer into the canine brain in vivo. Neurosurgery. 2007;60:167-178.
-
(2007)
Neurosurgery
, vol.60
, pp. 167-178
-
-
Candolfi, M.1
Kroeger, K.M.2
Pluhar, G.E.3
-
45
-
-
34547445754
-
Optimization of adenoviral vector mediated expression in the canine brain in vivo, and in canine glioma cells in vitro
-
Candolfi M, Pluhar GE, Kroeger KM, et al. Optimization of adenoviral vector mediated expression in the canine brain in vivo, and in canine glioma cells in vitro. Neuro-oncology. 2007;9:245-58.
-
(2007)
Neuro-oncology
, vol.9
, pp. 245-258
-
-
Candolfi, M.1
Pluhar, G.E.2
Kroeger, K.M.3
-
46
-
-
4644330301
-
FDA perspective on the use of the adenovirus reference material
-
Simek S, Byrnes A, Bauer S. FDA perspective on the use of the adenovirus reference material. Bioprocessing. 2002;31:40-42.
-
(2002)
Bioprocessing
, vol.31
, pp. 40-42
-
-
Simek, S.1
Byrnes, A.2
Bauer, S.3
-
47
-
-
0742307422
-
Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates
-
Brunetti-Pierri N, Palmer DJ, Beaudet AL, et al. Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates. Hum Gene Ther. 2004;15:35-46.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 35-46
-
-
Brunetti-Pierri, N.1
Palmer, D.J.2
Beaudet, A.L.3
-
48
-
-
0033541522
-
Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo
-
Muruve DA, Barnes MJ, Stillman IE, et al. Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo. Hum Gene Ther. 1999;10:965-976.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 965-976
-
-
Muruve, D.A.1
Barnes, M.J.2
Stillman, I.E.3
-
49
-
-
2442638935
-
Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo
-
Muruve DA, Cotter MJ, Zaiss AK, et al. Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo. J Virol. 2004;78:5966-5972.
-
(2004)
J Virol
, vol.78
, pp. 5966-5972
-
-
Muruve, D.A.1
Cotter, M.J.2
Zaiss, A.K.3
-
50
-
-
17844393413
-
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors
-
Schnell MA, Zhang Y, Tazelaar J, et al. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Mol Ther. 2001;3:708-722.
-
(2001)
Mol Ther
, vol.3
, pp. 708-722
-
-
Schnell, M.A.1
Zhang, Y.2
Tazelaar, J.3
-
51
-
-
0034986416
-
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
-
Zhang Y, Chirmule N, Gao GP, et al. Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol Ther. 2001;3:697-707
-
(2001)
Mol Ther
, vol.3
, pp. 697-707
-
-
Zhang, Y.1
Chirmule, N.2
Gao, G.P.3
-
52
-
-
8744294799
-
Effect of vimentin on reactive gliosis: In vitro and in vivo analysis
-
Lin J, Cai W. Effect of vimentin on reactive gliosis: in vitro and in vivo analysis. J Neurotrauma. 2004;21:1671-1682.
-
(2004)
J Neurotrauma
, vol.21
, pp. 1671-1682
-
-
Lin, J.1
Cai, W.2
-
53
-
-
0033519334
-
Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin
-
Pekny M, Johansson CB, Eliasson C, et al. Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin. J Cell Biol. 1999;145:503-514.
-
(1999)
J Cell Biol
, vol.145
, pp. 503-514
-
-
Pekny, M.1
Johansson, C.B.2
Eliasson, C.3
-
54
-
-
2542512476
-
Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration
-
Wilhelmsson U, Li L, Pekna M, et al. Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration. J Neurosci. 2004;24:5016-5021.
-
(2004)
J Neurosci
, vol.24
, pp. 5016-5021
-
-
Wilhelmsson, U.1
Li, L.2
Pekna, M.3
-
55
-
-
7044235842
-
AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: A randomised, controlled study
-
Immonen A, Vapalahti M, Tyynela K, et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther. 2004;10:967-972.
-
(2004)
Mol Ther
, vol.10
, pp. 967-972
-
-
Immonen, A.1
Vapalahti, M.2
Tyynela, K.3
-
56
-
-
0034840181
-
Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells
-
Kikuchi T, Akasaki Y, Irie M, et al. Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells. Cancer Immunol Immunother. 2001;50:337-344.
-
(2001)
Cancer Immunol Immunother
, vol.50
, pp. 337-344
-
-
Kikuchi, T.1
Akasaki, Y.2
Irie, M.3
-
57
-
-
0034694011
-
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
Rainov NG. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther. 2000;11:2389-2401.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 2389-2401
-
-
Rainov, N.G.1
-
58
-
-
20344372430
-
Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma: Results of a clinical phase I/II trial
-
Yamanaka R, Homma J, Yajima N, et al. Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma: results of a clinical phase I/II trial. Clin Cancer Res. 2005;11:4160-4167
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4160-4167
-
-
Yamanaka, R.1
Homma, J.2
Yajima, N.3
-
59
-
-
33749003484
-
Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors
-
El Andaloussi A, Sonabend AM, Han Y, et al. Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors. Glia. 2006;54:526-535.
-
(2006)
Glia
, vol.54
, pp. 526-535
-
-
El Andaloussi, A.1
Sonabend, A.M.2
Han, Y.3
-
60
-
-
33845885624
-
Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells
-
Fecci PE, Sweeney AE, Grossi PM, et al. Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. Clin Cancer Res. 2006;12:4294-4305.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4294-4305
-
-
Fecci, P.E.1
Sweeney, A.E.2
Grossi, P.M.3
-
61
-
-
0033957941
-
Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma
-
Heimberger AB, Crotty LE, Archer GE, et al. Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma. J Neuroimmunol. 2000;103:16-25.
-
(2000)
J Neuroimmunol
, vol.103
, pp. 16-25
-
-
Heimberger, A.B.1
Crotty, L.E.2
Archer, G.E.3
-
62
-
-
13444292787
-
Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas
-
Jiang H, Gomez-Manzano C, Alemany R, et al. Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas. Neoplasia. 2005;7:48-56.
-
(2005)
Neoplasia
, vol.7
, pp. 48-56
-
-
Jiang, H.1
Gomez-Manzano, C.2
Alemany, R.3
-
63
-
-
29244442698
-
Cyclophosphamide allows for in vivo dose reduction of a potent oncolytic virus
-
Kambara H, Saeki Y, Chiocca EA. Cyclophosphamide allows for in vivo dose reduction of a potent oncolytic virus. Cancer Res. 2005;65:11255-11258.
-
(2005)
Cancer Res
, vol.65
, pp. 11255-11258
-
-
Kambara, H.1
Saeki, Y.2
Chiocca, E.A.3
-
64
-
-
23444439371
-
Delivery of dendritic cells engineered to secrete IFN-alpha into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: Dependence on apoptotic pathways
-
Kuwashima N, Nishimura F, Eguchi J, et al. Delivery of dendritic cells engineered to secrete IFN-alpha into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: dependence on apoptotic pathways. J Immunol. 2005;175:2730-2740.
-
(2005)
J Immunol
, vol.175
, pp. 2730-2740
-
-
Kuwashima, N.1
Nishimura, F.2
Eguchi, J.3
-
65
-
-
0020606340
-
Breast carcinoma: Pattern of metastasis at autopsy
-
Lee YT. Breast carcinoma: pattern of metastasis at autopsy. J Surg Oncol. 1983;23:175-180.
-
(1983)
J Surg Oncol
, vol.23
, pp. 175-180
-
-
Lee, Y.T.1
-
66
-
-
0018112252
-
Intracranial metastases from systemic cancer
-
Posner JB, Chernik NL. Intracranial metastases from systemic cancer. Adv Neurol. 1978;19:579-592.
-
(1978)
Adv Neurol
, vol.19
, pp. 579-592
-
-
Posner, J.B.1
Chernik, N.L.2
-
67
-
-
0024271627
-
Brain metastases in adenocarcinoma of the lung: Frequency, risk groups, and prognosis
-
Sorensen JB, Hansen HH, Hansen M, et al. Brain metastases in adenocarcinoma of the lung: frequency, risk groups, and prognosis. J Clin Oncol. 1988;6:1474-1480.
-
(1988)
J Clin Oncol
, vol.6
, pp. 1474-1480
-
-
Sorensen, J.B.1
Hansen, H.H.2
Hansen, M.3
-
68
-
-
0038069255
-
Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma
-
Yang WQ, Senger D, Muzik H, et al. Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma. Cancer Res. 2003;63:3162-3172.
-
(2003)
Cancer Res
, vol.63
, pp. 3162-3172
-
-
Yang, W.Q.1
Senger, D.2
Muzik, H.3
-
69
-
-
0028881916
-
Adenovirus-mediated gene therapy in an experimental model of breast cancer metastatic to the brain
-
Colak A, Goodman JC, Chen SH, et al. Adenovirus-mediated gene therapy in an experimental model of breast cancer metastatic to the brain. Hum Gene Ther. 1995;6:1317-1322.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1317-1322
-
-
Colak, A.1
Goodman, J.C.2
Chen, S.H.3
-
70
-
-
10144229106
-
Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene
-
Vincent AJ, Esandi MD, van Someren G, et al. Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene. J Neurosurg. 1996;85:648-654.
-
(1996)
J Neurosurg
, vol.85
, pp. 648-654
-
-
Vincent, A.J.1
Esandi, M.D.2
van Someren, G.3
-
71
-
-
7244253093
-
Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer
-
Yang WQ, Senger DL, Lun XQ, et al. Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer. Gene Ther. 2004;11:1579-1589.
-
(2004)
Gene Ther
, vol.11
, pp. 1579-1589
-
-
Yang, W.Q.1
Senger, D.L.2
Lun, X.Q.3
-
72
-
-
0032505773
-
Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1
-
Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Hum Gene Ther. 1998;9:2177-2185.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2177-2185
-
-
Toda, M.1
Rabkin, S.D.2
Martuza, R.L.3
-
73
-
-
0025804166
-
Intra-thecal treatment of leptomeningeal lymphoma with immunotoxin
-
Urch CE, George AJ, Stevenson GT, et al. Intra-thecal treatment of leptomeningeal lymphoma with immunotoxin. Int J Cancer. 1991;47:909-915.
-
(1991)
Int J Cancer
, vol.47
, pp. 909-915
-
-
Urch, C.E.1
George, A.J.2
Stevenson, G.T.3
-
74
-
-
0036167471
-
In situ cancer vaccination with a replication-conditional HSV for the treatment of liver metastasis of colon cancer
-
Endo T, Toda M, Watanabe M, et al. In situ cancer vaccination with a replication-conditional HSV for the treatment of liver metastasis of colon cancer. Cancer Gene Ther. 2002;9:142-148.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 142-148
-
-
Endo, T.1
Toda, M.2
Watanabe, M.3
-
75
-
-
0034980707
-
Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters
-
Nakano K, Todo T, Chijiiwa K, et al. Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters. Mol Ther. 2001;3:431-437.
-
(2001)
Mol Ther
, vol.3
, pp. 431-437
-
-
Nakano, K.1
Todo, T.2
Chijiiwa, K.3
-
76
-
-
0034294865
-
Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor
-
Toda M, Martuza RL, Rabkin SD. Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor. Mol Ther. 2000;2:324-329.
-
(2000)
Mol Ther
, vol.2
, pp. 324-329
-
-
Toda, M.1
Martuza, R.L.2
Rabkin, S.D.3
-
77
-
-
0033540654
-
Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity
-
Toda M, Rabkin SD, Kojima H, et al. Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Hum Gene Ther. 1999;10:385-393.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 385-393
-
-
Toda, M.1
Rabkin, S.D.2
Kojima, H.3
-
78
-
-
0025372313
-
A new rat brain tumor model: Glioma disseminated via the cerebral spinal fluid pathways
-
Rewers AB, Redgate ES, Deutsch M, et al. A new rat brain tumor model: glioma disseminated via the cerebral spinal fluid pathways. J Neurooncol. 1990;8:213-219.
-
(1990)
J Neurooncol
, vol.8
, pp. 213-219
-
-
Rewers, A.B.1
Redgate, E.S.2
Deutsch, M.3
-
79
-
-
0031179187
-
An HSVtk-mediated local and distant antitumor bystander effect in tumors of head and neck origin in athymic mice
-
Bi W, Kim YG, Feliciano ES, et al. An HSVtk-mediated local and distant antitumor bystander effect in tumors of head and neck origin in athymic mice. Cancer Gene Ther. 1997;4:246-252.
-
(1997)
Cancer Gene Ther
, vol.4
, pp. 246-252
-
-
Bi, W.1
Kim, Y.G.2
Feliciano, E.S.3
-
80
-
-
0029843909
-
Suicide gene therapy for plasma cell tumors
-
Dilber MS, Abedi MR, Bjorkstrand B, et al. Suicide gene therapy for plasma cell tumors. Blood. 1996;88:2192-2200.
-
(1996)
Blood
, vol.88
, pp. 2192-2200
-
-
Dilber, M.S.1
Abedi, M.R.2
Bjorkstrand, B.3
-
81
-
-
0027973509
-
Adenovirus-mediated gene therapy of experimental gliomas
-
Perez-Cruet MJ, Trask TW, Chen SH, et al. Adenovirus-mediated gene therapy of experimental gliomas. J Neurosci Res. 1994;39:506-511.
-
(1994)
J Neurosci Res
, vol.39
, pp. 506-511
-
-
Perez-Cruet, M.J.1
Trask, T.W.2
Chen, S.H.3
-
82
-
-
0030917683
-
Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression
-
Vile RG, Castleden S, Marshall J, et al. Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression. Int J Cancer. 1997;71:267-274.
-
(1997)
Int J Cancer
, vol.71
, pp. 267-274
-
-
Vile, R.G.1
Castleden, S.2
Marshall, J.3
-
83
-
-
0030000923
-
HSV-tk gene therapy in head and neck squamous cell carcinoma. Enhancement by the local and distant bystander effect
-
Wilson KM, Stambrook PJ, Bi WL, et al. HSV-tk gene therapy in head and neck squamous cell carcinoma. Enhancement by the local and distant bystander effect. Arch Otolaryngol Head Neck Surg. 1996;122:746-749.
-
(1996)
Arch Otolaryngol Head Neck Surg
, vol.122
, pp. 746-749
-
-
Wilson, K.M.1
Stambrook, P.J.2
Bi, W.L.3
|