Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials

Nature Medicine

Volumn 5, Issue 11, 1999, Pages 1256-1263

  Dewey, R A ^d   Morrissey, G ^a   Cowsill, C M ^a   Stone, D ^a   Bolognani, F ^a   Dodd, N J F ^a   Southgate, T D ^a   Klatzmann, D ^b   Lassmann, H ^c   Castro, M G ^a   Lowenstein P R ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITY OF VIENNA   (Austria)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; GANCICLOVIR; THYMIDINE KINASE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DEMYELINATION; ENCEPHALITIS; GENE THERAPY; GLIOMA; HERPES SIMPLEX VIRUS; HISTOPATHOLOGY; IMMUNOREACTIVITY; INFLAMMATORY INFILTRATE; ISOGRAFT; MACROPHAGE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; T LYMPHOCYTE; TRANSGENE; TUMOR CELL DESTRUCTION;

ADENOVIRIDAE; ANIMALS; ASTROCYTES; BASE SEQUENCE; BRAIN NEOPLASMS; CLINICAL TRIALS; DNA PRIMERS; ENCEPHALITIS; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; GLIOMA; HERPESVIRUS 1, HUMAN; HUMANS; LYMPHOCYTES; MACROPHAGE ACTIVATION; MICROGLIA; MYELIN SHEATH; RATS; THYMIDINE KINASE; TRANSGENES; TUMOR CELLS, CULTURED;

EID: 0032741719     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/15207     Document Type: Article

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