Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs

Journal of Applied Physiology

Volumn 104, Issue 2, 2008, Pages 354-362

  Miyahara, Takashige ^a,b   Hamanaka, Kazutoshi ^a,b   Weber, David S ^a   Anghelescu, Mircea ^a,b   Frost, James R ^a,b   King, Judy A ^b   Parker, James C ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Capillary permeability; Cyclooxygenase; Cytochrome P 450; Leukotrienes; Lipoxygenase; Ventilator induced lung injury

Indexed keywords

17 OCTADECYNOIC ACID; ARACHIDONIC ACID; ARACHIDONYL TRIFLUOROMETHYL KETONE; CYTOCHROME P450 INHIBITOR; CYTOPLASM PROTEIN; IBUPROFEN; LIPOXYGENASE INHIBITOR; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE INHIBITOR; ARACHIDONIC ACID DERIVATIVE; ARACHIDONYLTRIFLUOROMETHANE; CYTOSOLIC PHOSPHOLIPASE A2; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ISOLATED LUNG; LUNG BLOOD VESSEL; LUNG INFLATION; LUNG INJURY; LUNG PRESSURE; LUNG VENTILATION; MALE; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VENTILATOR; ANIMAL; ARTIFICIAL VENTILATION; C57BL MOUSE; CAPILLARY PERMEABILITY; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IN VITRO STUDY; LUNG; LUNG CIRCULATION; LUNG DISEASE; LUNG LAVAGE; METABOLISM; MICROCIRCULATION; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE; VASCULARIZATION;

ANIMALS; ARACHIDONIC ACID; ARACHIDONIC ACIDS; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARY PERMEABILITY; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; ENZYME INHIBITORS; IBUPROFEN; LIPOXYGENASE INHIBITORS; LUNG; LUNG DISEASES; MALE; MICE; MICE, INBRED C57BL; MICROCIRCULATION; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHORYLATION; PULMONARY CIRCULATION; RESPIRATION, ARTIFICIAL; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE;

EID: 38949206901     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00959.2006     Document Type: Article

References (47)

1. Alvarez DF, King JA, Weber D, Addison E, Liedtke W, Townsley MI. Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circ Res 99: 988-995, 2006.
2. Alvarez DF, Gjerde EA, Townsley MI. Role of EETs in regulation of endothelial permeability in rat lung. Am J Physiol Lung Cell Mol Physiol 286: L445-L451, 2004.
3. 2 inhibition in vitro. J Biol Chem 269: 19081-19087, 1994.
4. Azuma N, Duzgun SA, Ikeda M, Kito H, Akasaka N, Sasajima T, Sumpio BE. Endothelial cell response to different mechanical forces. J Vasc Surg 32: 789-794, 2000.
5. Bhattacharya J. Interpreting the lung microvascular filtration coefficient. Am J Physiol Lung Cell Mol Physiol 293: L9-L10, 2007.
6. Bogatcheva NV, Sergeeva MG, Dudek SM, Verin AD. Arachidonic acid cascade in endothelial pathobiology. Microvasc Res 69: 107-127, 2005.
7. Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and respiratory distress syndrome. N Engl J Med 342: 1301-1308, 2000.
8. Caironi P, Ichinose F, Liu R, Jones RC, Bloch KD, Zapol WM. 5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury. Am J Respir Crit Care Med 172: 334-343, 2005.
9. Curry FE. Mechanics and thermodynamics of transcapillary exchange. In: Handbook of Physiology. The Cardiovascular System. Microcirculation. Bethesda, MD: Am. Physiol. Soc., 1984, sect. 2, vol. IV, pt. 1, chapt. 8, p. 309-374.
10. Falk S, Goggel R, Heydasch U, Brasch F, Muller KM, Wendel A, Uhlig S. Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation. Am J Respir Crit Care Med 160: 1734-1742, 1999.
11. Frank JA, Matthay MA. Leukotrienes in acute lung injury: a potential therapeutic target? Am J Respir Crit Care Med 172: 261-262, 2005.
12. Gama de Abreau M, Wilmink B, Hubler M, Koch T. Vaporized perfluorohexane attenuates ventilator-induced lung injury in isolated, perfused rabbit lungs. Anesthesiology 102: 597-605, 2005.
13. 2, E-prostanoid 3-receptors, and potassium channels. Am J Respir Crit Care Med 166: 657-662, 2001.
14. Goggel R, Uhlig S. The inositol trisphosphate pathway mediates platelet-activating factor-induced pulmonary oedema. Eur Respir J 25: 849-857, 2005.
15. Hamanaka K, Jian MY, Weber DS, Alvarez DF, Townsley MI, Al Mehdi AB, King JA, Liedtke W, Parker JC. TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. Am J Physiol Lung Cell Mol Physiol 293: L923-L932, 2007.
16. Hino Si Tanji C, Nakayama KI, Kikuchi A. Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination. Mol Cell Biol 25: 9063-9072, 2005.
17. Hybertson BM, Bursten SL, Leff JA, Lee YM, Jepson EK, Dewitt CR, Zagorski J, Cho HG, Repine JE. Lisofylline prevents leak, but not neutrophil accumulation, in lungs of rats given IL-1 intratracheally. J Appl Physiol 82: 226-232, 1997.
18. 2 gene in inbred mouse strains. J Biol Chem 270: 22378-22385, 1995.
19. Kuebler WM, Kuhnle GE, Goetz AE. Leukocyte margination in alveolar capillaries: interrelationship with functional capillary geometry and microhemodynamics. J Vasc Res 36: 282-288, 1999.
20. 2. J Biol Chem 272: 16709-16712, 1997.
21. 4 in pulmonary edema fluid of patients with the adult respiratory distress syndrome. J Clin Immunol 4: 479-483, 1984.
22. McLean PG, Aston D, Sarkar D, Ahluwalia A. Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia/reperfusion injury: involvement of lipoxygenase products, VR1 receptors, and C-fibers. Circ Res 90: 465-472, 2002.
23. 2. J Biochem (Tokyo) 131: 285-292, 2002.
24. 2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 284: L720-L726, 2003.
25. 2. Nat Immunol 1: 42-46, 2000.
26. 2 and platelet-activating factor acetylhydrolase in patients with acute respiratory distress syndrome. Crit Care Med 33: 772-779, 2005.
27. 2+ mobilization to mechanical stretch in endothelial cells. Am J Physiol Cell Physiol 264: C1037-C1044, 1993.
28. Nilius B, Droogmans G. Ion channels and their functional role in vascular endothelium. Physiol Rev 81: 1415-1459, 2001.
29. Park GY, Christman JW. Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases. Am J Physiol Lung Cell Mol Physiol 290: L797-L805, 2006.
30. Parker JC, Gillespie MN, Taylor AE, Martin SL. Capillary filtration coefficient, vascular resistance, and compliance in isolated mouse lungs. J Appl Physiol 87: 1421-1427, 1999.
31. Parker JC, Ivey C, Tucker A. Gadolinium prevents high airway pressure-induced permeability increases in isolated rat lungs. J Appl Physiol 84: 1113-1118, 1998.
32. Parker JC, Ivey CL, Tucker A. Phosphotyrosine phosphatase and tyrosine inhibition modulate airway pressure-induced lung injury. J Appl Physiol 85: 1753-1761, 1998.
33. Parker JC, Townsley MI. Evaluation of lung injury in rats and mice. Am J Physiol Lung Cell Mol Physiol 286: L231-L246, 2004.
34. Parker JC, Yoshikawa S. Vascular segmental permeabilities at high peak inflation pressure in isolated rat lungs. Am J Physiol Lung Cell Mol Physiol 283: L1203-L1209, 2002.
35. 2) and MAP kinase in human endothelial cells. Biochem Biophys Res Commun 218: 500-504, 1996.
36. Ricard JD, Dreyfuss D, Saumon G. Production of inflammatory cytokines in ventilator-induced lung injury: a reappraisal. Am J Respir Crit Care Med 163: 1176-1180, 2001.
37. 4 activates alveolar epithelial Na,K-ATPase and increases alveolar fluid clearance. Am J Respir Crit Care Med 169: 407-412, 2004.
38. Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD. OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol 2: 695-702, 2000.
39. Tankersley CG, Rabold R, Mitzner W. Differential lung mechanics are genetically determined in inbred murine strains. J Appl Physiol 86: 1764-1769, 1999.
40. Taylor AE, Parker JC. The interstitial spaces and lymph flow. In: Handbook of Physiology. The Respiratory System. Circulation and Nonrespiratory Function. Bethesda, MD: Am. Physiol. Soc., 1985, sect. 3, vol. I, chapt. 4, p. 167-320.
41. Von Bethmann AN, Brasch F, Nusing R, Vogt K, Volk HD, Muller KM, Wendel A, Uhlig S. Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med 157: 263-272, 1998.
42. Wang MH, Brand-Schieber E, Zand BA, Nguyen X, Falck JR, Balu N, Schwartzman ML. Cytochrome P-450-derived arachidonic acid metabolism in the rat kidney: characterization of selective inhibitors. J Pharmacol Exp Ther 284: 966-973, 1998.
43. Watanabe H. Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem 277: 13569-13577, 2002.
44. Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T, Nilius B. Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature 424: 434-438, 2003.
45. Yoshikawa S, King JA, Lausch RN, Penton AM, Eyal FG, Parker JC. Acute ventilator-induced vascular permeability and cytokine responses in isolated and in situ mouse lungs. J Appl Physiol 97: 2190-2199, 2004.
46. 2 activity modulate acute ventilator-induced lung injury in mice. J Appl Physiol 98: 1264-1271, 2005.
47. 2 activation in arachidonic acid metabolism in human eosinophils. J Immunol 167: 461-468, 2001.