Capillary filtration coefficient, vascular resistance, and compliance in isolated mouse lungs

Journal of Applied Physiology

Volumn 87, Issue 4, 1999, Pages 1421-1427

  Parker, James C ^a,b   Gillespie, Mark N ^b   Taylor, Aubrey E ^a   Martin, Sherri L ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Capillary filtration coefficient; Mechanical stress failure; Pulmonary edema; Transgenic mice; Vasoconstriction

Indexed keywords

BOVINE SERUM ALBUMIN; PHENYLEPHRINE;

ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL COMPLIANCE; BLOOD VESSEL FUNCTION; BLOOD VESSEL INJURY; CAPILLARY PERMEABILITY; CONTROLLED STUDY; LUNG BLOOD VESSEL; LUNG EDEMA; LUNG PERFUSION; MALE; MECHANICAL STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 0032843156     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1999.87.4.1421     Document Type: Article

References (17)

1. Brower, R. G., J. T. Sylvester, and S. Permutt. Flow-volume characteristics in the pulmonary circulation. J. Appl. Physiol. 69: 1746-1753, 1990.
2. Caruthers, S. D., and T. R. Harris. Effects of pulmonary blood flow on the fractal nature of flow heterogeneity in sheep lungs. J. Appl. Physiol. 77: 1474-1479, 1994.
3. Fujimoto, K., J. C. Parker, and S. G. Kayes. Activated eosinophils increase vascular permeability and resistance in isolated perfused rat lungs. Am. Rev. Respir. Dis. 142: 1414-1421, 1990.
4. Hernandez, L. A., K. J. Peevy, A. A. Moise, and J. C. Parker. Chest wall restriction limits high airway pressure-induced lung injury in young rabbits. J. Appl. Physiol. 66: 2364-2368, 1989.
5. Mathieu-Costello, O., D. C. Willford, Z. Fu, R. M. Garden, and J. B. West. Pulmonary capillaries are more resistant to stress failure in dogs than in rabbits. J. Appl. Physiol. 79: 908-917, 1995.
6. Parker, J. C., L. A. Hernandez, and K. Peevy. Mechanisms of ventilator induced injury. Crit. Care Med. 21: 131-143, 1993.
7. Parker, J. C., C. Ivey, and A. Tucker. Gadolinium prevents high airway pressure-induced permeability increases in isolated rat lungs. J. Appl. Physiol. 84: 1113-1118, 1998.
8. Parker, J. C., and C. L. Ivey. Isoproterenol attenuates high vascular pressure-induced permeability increases in isolated rat lungs. J. Appl. Physiol. 83: 1962-1967, 1998.
9. Parker, J. C., R. Prasad, R. A. Allison, W. V. Wojchiechowski, and S. L. Martin. Capillary filtration coefficients using laser densitometry and gravimetry in isolated dog lungs. J. Appl. Physiol. 74: 1981-1987, 1993.
10. Parker, J. C., M. I. Townsley, B. Rippe, A. E. Taylor, and J. Thigpen. Increased microvascular permeability in dog lungs due to high peak airway pressures. J. Appl. Physiol. 57: 1809-1816, 1984.
11. Rippe, B., J. C. Parker, M. I. Townsley, N. A. Mortillaro, and A. E. Taylor. Segmental vascular resistances and compliances in dog lung. J. Appl. Physiol. 62: 1206-1215, 1987.
12. Seibert, A. F., W. J. Thompson, A. E. Taylor, W. H. Wilborn, and J. W. Barnard. Reversal of increased microvascular permeability associated with ischemia reperfusion: role of cAMP. J. Appl. Physiol. 72: 389-395, 1992.
13. Steudel, W., F. Ichinose, P. L. Huang, W. E. Hurford, R. C. Jones, J. A. Bevan, M. C. Fishman, and W. M. Zapol. Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ. Res. 81: 34-41, 1997.
14. Taylor, A. E., and J. C. Parker. Pulmonary interstitial spaces and lymphatics. In: Handbook of Physiology. The Respiratory System. Circulation and Nonrespiratory Function. Bethesda, MD: Am. Physiol. Soc., 1985, sect. 3, vol. I, chapt. 4, p. 167-230.
15. Taylor, A. E., K. Rehder, R. E. Hyatt, and J. C. Parker. Clinical Respiratory Physiology. Philadelphia, PA: Saunders, 1989.
16. Von Bethmann, A. N., F. Brasch, R. Nusing, K. Vogt, H. D. Volk, K.-M. Muller, A. Wendel, and S. Uhlig. Hyperventilation induces release of cytokines from perfused mouse lung. Am. J. Respir. Crit. Care Med. 157: 263-272, 1998.
17. Yoshikawa, S., S. G. Kayes, and J. C. Parker. Eosinophils increase lung microvascular permeability via the peroxidase-hydrogen peroxide-halide system. Bronchoconstriction and vasoconstriction are unaffected by eosinophil peroxidase inhibition. Am. Rev. Respir. Dis. 147: 914-920, 1993.