Differential lung mechanics are genetically determined in inbred murine strains

Journal of Applied Physiology

Volumn 86, Issue 6, 1999, Pages 1764-1769

  Tankersley, Clarke G ^a   Rabold, Richard ^a   Mitzner, Wayne ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

A J; BXH recombinant inbred strains; C3H HeJ; C57BL 6J; Control of breathing

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BREATHING MECHANICS; CHROMOSOME 3; GENE LOCATION; GENETIC VARIABILITY; LUNG VOLUME; MOUSE; NONHUMAN; PHENOTYPE; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; RESPIRATION CONTROL; STRAIN DIFFERENCE;

EID: 0033060932     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1999.86.6.1764     Document Type: Article

References (28)

1. Agostoni, E., E. D'Angelo, and M. Piulini. Breathing pattern in men during inspiratory elastic loads. Respir. Physiol. 34: 279-393, 1978.
2. Agostoni, E., F. F. Thimm, and W. O. Fenn. Comparative features of the mechanics of breathing. J. Appl. Physiol. 679-683, 1959.
3. Axen, K., S. S. Haas, F. Haas, D. Gaudino, and A. Haas. Ventilatory adjustments during sustained mechanical loading in conscious humans. J. Appl. Physiol. 55: 1211-1218, 1983.
4. Bachofen, H., and J. Hildebrandt. Area analysis of pressure-volume hysteresis in mammalian lung. J. Appl. Physiol. 30: 493-497, 1971.
5. Bachofen, H., S. Schüren, M. Urbinelli, and E. R. Weibel. Relations among alveolar surface tension, surface area, volume, and recoil pressure. J. Appl. Physiol. 62: 1878-1887, 1987.
6. Bennett, F. M., and S. M. Tenney. Comparative mechanics of mammalian respiratory system. Respir. Physiol. 49: 131-140, 1982.
7. Clements, J. A. Dependence of pressure-volume characteristics of lungs on intrinsic surface-active material (Abstract). Am. J. Physiol. 187: 592, 1956.
8. Crosfill, M. L., and J. G. Widdicombe. Physical characteristics of the chest and lungs and the work of breathing in different mammalian species. J. Physiol. (Lond.) 158: 1-14, 1961.
9. DeSanctis, G. T., M. Merchant, D. R. Beier, R. D. Dredge, J. K. Grobholz, T. R. Martin, E. S. Lander, and J. M. Drazen. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat. Genet. 11: 150-154, 1995.
10. Ewart, S. L., W. Mitzner, D. A. DiSilvestre, D. A. Meyers, and R. C. Levitt. Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6. Am. J. Respir. Cell Mol. Biol. 14: 487-495, 1995.
11. Frazer, D. G., and K. C. Weber. Trapped air in ventilated excised rat lungs. J. Appl. Physiol. 40: 915-922, 1976.
12. Fredberg, J. J., and D. Stamenovic. On the imperfect elasticity of lung tissue. J. Appl. Physiol. 67: 2408-2419, 1989.
13. Freedman, S., and S. A. Weinstein. Effects of external elastic and threshold loading on breathing in man. J. Appl. Physiol. 20: 469-472, 1965.
14. Greska, L. P. Evidence for a genetic basis to the functional total lung capacity of Andean highlanders. Hum. Biol. 68: 119-129, 1996.
15. Leith, D. E. Comparative mammalian respiratory mechanics. Physiologist 19: 485-510, 1976.
16. Levitt, R. C., and W. Mitzner. Autosomal recessive inheritance of airway hyperreactivity to 5-hydroxytryptamine. J. Appl. Physiol. 67: 1125-1132, 1989.
17. Levitt, R. C., W. Mitzner, and S. R. Kleeberger. A genetic approach to the study of lung physiology: understanding biological variability in airway responsiveness. Am. J. Physiol. 258 (Lung Cell. Mol. Physiol. 2): L157-L164, 1990.
18. Mitzner, W., J. W. C. Johnson, R. Scott, W. T. London, and A. E. Palmer. Effect of betamethasone on pressure-volume relationship of fetal rhesus monkey lung. J. Appl. Physiol. 47: 377-382, 1979.
19. Mitzner, W., and S. Permutt. Effect of ventilation on the surface properties of the lung. Prog. Respir. Res. 15: 194-206, 1981.
20. Moore, K. J., M. A. D'Amore-Bruno, T. R. Korfhagen, S. W. Glasser, J. A. Whitsett, N. A. Jenkins, and N. G. Copeland. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992.
21. O'Donnell, D. E., R. Sanii, and M. Younes. External mechanical loading in conscious humans: role of upper airway mechanoreceptors. J. Appl. Physiol. 65: 541-548, 1988.
22. Pope, H., R. Holloway, and E. J. M. Campbell. The effects of elastic and resistive loading of inspiration on the breathing of conscious man. Respir. Physiol. 4: 363-372, 1968.
23. Puddy, A., and M. Younes. Effect of slowly increasing elastic load on breathing in conscious humans. J. Appl. Physiol. 70: 1277-1283, 1991.
24. Tankersley, C. G., D. A. DiSilvestre, A. E. Jedlicka, H. M. Wilkins, and L. Zhang. Differential inspiratory timing is genetically linked to mouse chromosome 3. J. Appl. Physiol. 85: 360-365, 1998.
25. Tankersley, C. G., R. S. Fitzgerald, and S. R. Kleeberger. Differential control of ventilation among inbred strains of mice. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R1371-R1377, 1994.
26. Tankersley, C. G., R. S. Fitzgerald, R. C. Levitt, W. A. Mitzner, S. L. Ewart, and S. R. Kleeberger. Genetic control of differential baseline breathing pattern. J. Appl. Physiol. 82: 874-881, 1997.
27. Taylor, B. A. Recombinant inbred strains. In: Genetic Variants and Strains of the Laboratory Mouse (2nd ed.), edited by M. Lyon and A. G. Searle. New York: Oxford Univ. Press, 1989, p. 773-779.
28. Wynder, K. S., J. L. Sechler, C. D. Boyd, and H. C. Passmore. Use of intron polymorphism to localize the tropoelastin gene to mouse chromosome 5 in a region of linkage conservation with human chromosome 7. Genomics 23: 125-131, 1994.