5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury

American Journal of Respiratory and Critical Care Medicine

Volumn 172, Issue 3, 2005, Pages 334-343

  Caironi, Pietro ^a   Ichinose, Fumito ^a   Liu, Rong ^a   Jones, Rosemary C ^a   Bloch, Kenneth D ^a   Zapol, Warren M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Hypoxic pulmonary vasoconstriction; Leukotrienes; Ventilator induced lung injury

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; VERLUKAST;

5 LIPOXYGENASE DEFICIENCY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BIOSYNTHESIS; BLOOD VESSEL PERMEABILITY; BREATHING MECHANICS; CONTROLLED STUDY; ENZYME DEFICIENCY; HYPOXEMIA; LUNG BLOOD FLOW; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; MOUSE; MOUSE STRAIN; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; RESPIRATORY FAILURE; STRAIN DIFFERENCE; SURVIVAL RATE; VENTILATOR;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; LEUKOTRIENES; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; PULMONARY CIRCULATION; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY INSUFFICIENCY; VASOCONSTRICTION; VENTILATORS, MECHANICAL;

EID: 22644432128     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200501-034OC     Document Type: Article

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