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Volumn 42, Issue 13, 1999, Pages 2351-2357

Pharmacophore development for corticotropin-releasing hormone: New insights into inhibitor activity

Author keywords

[No Author keywords available]

Indexed keywords

ANTALARMIN; BETA ENDORPHIN; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR DERIVATIVE; CORTICOTROPIN RELEASING FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 0033168446     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9900117     Document Type: Article
Times cited : (38)

References (25)
  • 1
    • 0019782980 scopus 로고
    • Characterization of a 41-residue ovine hypothalic peptide that stimulates secretion of corticotropin and β-endorphin
    • Vale, W.; Spiess, C.; Rivier, C. Characterization of a 41-Residue Ovine Hypothalic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin. Science 1981, 213, 1394-1397.
    • (1981) Science , vol.213 , pp. 1394-1397
    • Vale, W.1    Spiess, C.2    Rivier, C.3
  • 3
    • 0029079579 scopus 로고
    • A placental clock controlling the length of human pregnancy
    • McClean, M.; Bisits, A.; Davies, J.; Lowry, P.; Smith, R. A Placental Clock Controlling the Length of Human Pregnancy. Nature Med. 1995, 1, 460-463.
    • (1995) Nature Med. , vol.1 , pp. 460-463
    • McClean, M.1    Bisits, A.2    Davies, J.3    Lowry, P.4    Smith, R.5
  • 8
    • 0344293656 scopus 로고
    • Corticotropin releasing hormone and parturition: Plasma and amniotic fluid levels and placental binding sites
    • Petraglia, F.; Giardino, L.; Coukos, G.; Calza, L.; Vale, W.; Genazzani, A. R. Corticotropin Releasing Hormone and Parturition: Plasma and Amniotic Fluid Levels and Placental Binding Sites. Obstet. Gynecol. 1990, 349, 423-426.
    • (1990) Obstet. Gynecol. , vol.349 , pp. 423-426
    • Petraglia, F.1    Giardino, L.2    Coukos, G.3    Calza, L.4    Vale, W.5    Genazzani, A.R.6
  • 11
    • 0027489208 scopus 로고
    • Expression cloning of a human corticotropin-releasing-factor receptor
    • Chen, R.; Lewis, K. A.; Perrin, M. H.; Vale, W. Expression Cloning of a Human Corticotropin-Releasing-Factor Receptor. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 8967-8971.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 8967-8971
    • Chen, R.1    Lewis, K.A.2    Perrin, M.H.3    Vale, W.4
  • 12
    • 0030838450 scopus 로고    scopus 로고
    • Expression of genes encoding corticotropin-releasing factor (CRF), type 1 CRF receptor, and CRF-binding protein and localization of the gene products in the human ovary
    • Asakura, H.; Zwain, I. H.; Yen, S. S. C. Expression of Genes Encoding Corticotropin-Releasing Factor (CRF), Type 1 CRF Receptor, and CRF-Binding Protein and Localization of the Gene Products in the Human Ovary. J. Clin. Endocrinol. Metab. 1997, 82 (8), 2720-2725.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.8 , pp. 2720-2725
    • Asakura, H.1    Zwain, I.H.2    Yen, S.S.C.3
  • 13
    • 0032480914 scopus 로고    scopus 로고
    • Constrained corticotropin-releasing factor (CRF) agonists and antagonists with i-(i+3) Glu-Xaa-DXbb-Lys bridges
    • Koerber, S. C.; Gulyas, J.; Lahrichi, S. L.; Corrigan, A.; Craig, A. C.; Rivier, C.; Vale, W.; Rivier, J. Constrained Corticotropin-Releasing Factor (CRF) Agonists and Antagonists with i-(i+3) Glu-Xaa-DXbb-Lys Bridges. J. Med. Chem. 1998, 41, 5002-5011.
    • (1998) J. Med. Chem. , vol.41 , pp. 5002-5011
    • Koerber, S.C.1    Gulyas, J.2    Lahrichi, S.L.3    Corrigan, A.4    Craig, A.C.5    Rivier, C.6    Vale, W.7    Rivier, J.8
  • 18
    • 0344768045 scopus 로고    scopus 로고
    • A corticotropin-releasing hormone type 1 receptor antagonist delays parturition in sheep
    • 1 antagonist antalarmin was administered as a 1:1 polyethoxylated castor oil/ethanol solution; see: Chan, E. C.; Falconer, J.; Madsen, G.; Rice, K. C.; Webster, E. L.; Chrousos, G. P.; Smith, R. A Corticotropin-Releasing Hormone Type 1 Receptor Antagonist Delays Parturition in Sheep. Endocrinology 1998, 139 (7), 3357-3360.
    • (1998) Endocrinology , vol.139 , Issue.7 , pp. 3357-3360
    • Chan, E.C.1    Falconer, J.2    Madsen, G.3    Rice, K.C.4    Webster, E.L.5    Chrousos, G.P.6    Smith, R.7
  • 21
    • 0344725657 scopus 로고    scopus 로고
    • Reference 18, Supporting Information
    • Reference 18, Supporting Information.
  • 22
    • 25544474045 scopus 로고    scopus 로고
    • Molecular Simulations, Inc., Burlington, MA
    • Catalyst v3.0; Molecular Simulations, Inc., Burlington, MA.
    • Catalyst v3.0
  • 23
    • 0005123846 scopus 로고
    • Automated chemical hypothesis generation and database searching with catalyst
    • Sprague, P. W. Automated Chemical Hypothesis Generation and Database Searching with Catalyst. Perspect. Drug Discovery Des. 1995, 3, 1-20.
    • (1995) Perspect. Drug Discovery Des. , vol.3 , pp. 1-20
    • Sprague, P.W.1
  • 24
    • 0031442297 scopus 로고    scopus 로고
    • Identification of novel farnesyl protein transferase inhibitors using three-dimensioanl database searching methods
    • Kaminski, J. J.; Rane, D. F.; Snow, M. E.; Weber, L.; Rothofsky, M. L.; Anderson, S. D.; Lin, S. L. Identification of Novel Farnesyl Protein Transferase Inhibitors Using Three-Dimensioanl Database Searching Methods. J. Med. Chem. 1997, 40, 4103-4112.
    • (1997) J. Med. Chem. , vol.40 , pp. 4103-4112
    • Kaminski, J.J.1    Rane, D.F.2    Snow, M.E.3    Weber, L.4    Rothofsky, M.L.5    Anderson, S.D.6    Lin, S.L.7
  • 25
    • 0344293652 scopus 로고    scopus 로고
    • note
    • The calculated fit function within the Catalyst program is a weighted value based on the number of features generated for each pharmacophore. Essentially, the higher the value the better the fit. Since our three hypotheses all contain five features, direct comparisons can be made.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.